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특발성 혈소판감소성 자반병과 쇼그렌씨 증후군이 동반된 원발성 담즙성 간경변증 1예
우태욱,김병호,심재준,김윤화,조경삼 대한내과학회 2004 대한내과학회지 Vol.66 No.1
저자들은 특발성 혈소판감소성 자반병을 가진 환자에서 전형적인 일차성 원발성 담즙성 간경변증의 양상이 나타나 혈청검사, 자가면역항체, 간조직 검사 등을 통해 특발성 혈소판감소성 자반병과 쇼그렌 증후군이 동반된 원발성 담즙성 간경변증 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다. Primary biliary cirrhosis (PBC) is rare in Korea. Although its pathogenesis is not fully understood, immunologic dysregulation is suspected because it is frequently associated with other immunologic disorders. A few cases of primary biliary cirrhosis associated with idiopathic thrombocytopenic purpura (ITP) has previously been reported. However, PBC associated with ITP and Sjo¨gren's syndrome simultaenously has not been reported yet. We experienced a 72-year-old woman had been finally diagnosed as PBC, ITP and Sjo¨gren's syndrome. To the best of our knowledge, this is the first case in the world. We report this case with review of related literature.
R.F. Magnetron Sputtering을 이용한 리튬이차전지 정극용 ${LiMn_2}{O_4}$의 제조 및 특성
우태욱,손영국 한국세라믹학회 2000 한국세라믹학회지 Vol.37 No.6
LiMn2O4 thin fiolm cathodes for Li-ion secondary battery were fabricated by r.f. magnetron sputtering technique. As-deposited films were amorphous. A spinel structure could not be obtained LiMn2O4 films by in-situ thermal annealing. After post thermal annealing over $700^{\circ}C$ in oxygen atmosphere, LiMn2O4 films prepared above 100 W r.f. power could be crystallized into a spinel structure. The electrochemical property of the LiMn2O4 film cathodes was tested in a Li/1 M LiClO4 in PC/LiMn2O4 cell. From cyclic voltammetry at scan rate of 2mV/sec of 2.5~4.5V, LiMn2O4 electrode prepared by post annealing at 75$0^{\circ}C$ showed good initial capacity. LiMn2O4 electrode prepared by post annealing at 80$0^{\circ}C$ showed the best crycling performance.
Sn-3.0Ag-0.5Cu 솔더재료의 피로 균열진전에 관한 연구
우태욱(Tae Wuk Woo),김광수(Kwang Soo Kim),Masao Sakane,Kaoru Kobayashi 대한기계학회 2008 대한기계학회 춘추학술대회 Vol.2008 No.11
This study investigates crack propagation behavior of Sn-3.0Ag-0.5Cu solder under pull-push loading conditions. Fatigue Crack Growth (FCG) tests were conducted on Center Cracked Plate (CCP) specimens in fast-fast (pp) strain waveform. The fast-slow (pc), slow-fast (cp) and slow-slow (cc) strain waveforms were also used to study the effect of strain rates. The crack propagation rates for the four strain waveforms were correlated with J-integral range and a scatter band of factor 4 was found. The crack growth rates for the pc waveform was highest, followed by cp, cc and then pp waveforms.
Sn-3.0Ag-0.5Cu 솔더재료의 크립-피로 균열진전에 대한 연구
우태욱(Tae Wuk Woo),Masao Sakane,Kaoru Kobayashi,박현철(Hyun Chul Park) 대한기계학회 2009 대한기계학회 춘추학술대회 Vol.2009 No.11
This study investigates crack growth behavior of Sn-3.0Ag-0.5Cu lead-free solder under creep-fatigue conditions. Crack growth tests were conducted using center-cracked-plate specimens in slow-fast (cp), fastslow (pc) and slow-slow (cc) strain waveforms with nominal strain control. The crack growth rates for the three strain waveforms were correlated with the creep J-integral range.
이태희,이연아,우태욱,고관표,박철영,우정택,김성운,김진우,김영설 대한내분비학회 2003 Endocrinology and metabolism Vol.18 No.1
A functioning paraganglioma is a rare catecholamine-producing tumor that arises from the extra-adrenal chromaffin tissue. Recently we experienced a case in which a 42 year-old male patient with a functioning extra-adrenal paraganglioma mimicked an acute coronary syndrome. A functioning extra-adrenal paraganglioma was diagnosed by means of a biochemical study and a radiological imaging study. After stabilizing his blood pressure, using alpha adrenergic blocker, we successfully removed a 6×6cm sized paraganglioma from between the aorta and the IVC in the retroperitoneal space(J Kor Soc Endocrinol 18:94~99, 2003). 카테콜아민을 분비하는 기능성 부신경절종은 드문 질환이며 급성 관동맥증후군으로 발현한 경우는 더욱 드물다. 이에 저자들은 혈압 변동이 심한 급성 관상동맥증후군 환자에서 기능성 부신경절종을 진단하여 성공적으로 치료한 1예를 경험했기에 문헌 고찰과 함께 보고하는 바이다.
백서 신장 조직내 Na^+-K^+ ATPase에 대한 Furosemide의 간접적 억제 기전
백행운,윤경식,우태욱,김재욱,이재범,백형환,조용호 慶熙大學校 大學院 1994 高凰論集 Vol.15 No.-
It is presented that the subcellular localization and distribution of the specific activity of Na^+-K^+ ATPase in whole homogenate, the soluble fraction and mitochondrial fraction of the renal tissues in normal adult rat isolated by differential centrifugal method were studied. The effect of furosemide compound on their enzymatic activity was evaluated by the Fiske SubbaRaw method. The specific activity of Na^+-K^+ ATPase of rat renal tissues was found to be about 92.2 umol/g protein/hr. The specific activity of microsomal fraction of rat renal tissue is showed approximately 1.5-fold higher than the value in the other fraction. The effect of furosemide was found to decrease proportionally the specific activity of Na^+-K^+ ATPase in rat renal tissue as the increment of the concentration of furosemide to luM in the microsomal fraction. The effect of the other diuretics is showed the same inhibition pattern. When the incubation time is increased from 15min to 60min in the same drug treated Na^+-K^+ ATPase, specific activity of Na^+-K^+ ATPase is increase but the inhibition rate of the enzyme is decreased. In view of the above finding, it is clear that the furosemide, well known as diuretic agent, selectively inhibits the activity of the microsomal Na^+-K^+ ATPase in accordance with dose-dependent effect. The mechanism of action appears to be due to indirect inhibition. Indirect inhibition means that the transport protein of cellularion in membrane is inhibited by the furosemide and so indirectly activity of Na^+-K^+ ATPase is inhibited by that. Consequently, the effect of the furosemide on the rat renal tissue Na^+-K^+ ATPase is non-specific inhibition by indirect inhibition of transport protein.
크레메진의 투석도입 지연효과에 따른 진행성 신부전증환자의 비용감소분 추계
조우현,이선미,김형종,이호영,우태욱,강혜영,Cho, Woo-Hyun,Lee, Sun-Mi,Kim, Hyung-Jong,Lee, Ho-Yong,Woo, Tae-Wook,Kang, Hye-Young 대한예방의학회 2006 예방의학회지 Vol.39 No.2
Objectives : We wanted to evaluate the economic value of a pharmaceutical product, Kremezin, for treating patients with chronic renal failure (CRF) by estimating the amount of cost savings due to its effect for delaying the initiation of dialysis treatments. Methods : We defined a conventional treatment for CRF accompanied by Kremezin therapy as 'the treatment group' and only conventional treatment as 'the alternative group.' The types of costs included were direct medical and nonmedical costs and costs of productivity loss. The information on the effect of Kremezin was obtained from the results of earlier clinical studies. Cost information was derived from the administrative data for 20 hemodialysis and 20 peritoneal dialysis patients from one tertiary care hospital, and also from the administrative data of 10 hemodialysis patients from one free-standing dialysis center. Per-capita cost savings resulting from Kremezin therapy were separately estimated for the cases with delay for the onset of hemodialysis and the cases with immediate performance of peritoneal dialysis. By computing the weighted average for the cases of hemodialysis and peritoneal dialysis, the expected per-capita cost savings of a patient with CRF was obtained. Using a discount rate of 5%, future cost savings were converted to the present value. Results : The present value of cumulative cost savings per patient with CRF from the societal perspective would be $18,555,000{\sim}29,410,000$ Won or $72,104,000{\sim}112,523,000$ Won if Kremezin delays the initiation of dialysis by 1 or 4 years. Conclusions : The estimated amount of cost savings resulting from treating CRF patients with Kremezin confirms that its effect for delaying the onset of dialysis treatments has a considerable economic value.