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- 저자 : 강상민(Kang Sang Min) (검색결과 11 건)
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2개 대비 1개의 난할기 선발배아 이식에 따른 임상 결과
강상민,이상원,정학준,채수진,윤산현,임진호,이성구,Kang, Sang-Min,Lee, Sang-Won,Jeong, Hak-Jun,Chae, Soo-Jin,Yoon, San-Hyun,Lim, Jin-Ho,Lee, Seong-Goo 대한생식의학회 2010 Clinical and Experimental Reproductive Medicine Vol.37 No.4
목적: 시험관아기 시술에서 3일째의 배아들 가운데 우수한 배아를 선발하여 1개의 배아를 이식 (elective single embryo transfer, eSET)한 주기와 2개의 배아를 이식 (elective double embryo transfer, eDET)한 주기의 임상적 결과들을 비교, 분석하고자 하였다. 연구방법: 본 연구는 2008년 1월부터 2009년 4월까지 대구마리아에서 첫 번째나 두 번째 In vitro fertilization-embryo transfer (IVF-ET)를 시행한 36세 미만인 환자들 가운데 hCG를 투여한 당일 자궁내막의 두께가 8 mm 이상이고 정상적인 수정란이 3개 이상이면서 적어도 1개의 우수한 배아를 지닌 환자들을 대상으로 실시하였다. eSET는 167주기에서 실시하였고 eDET는 163주기에서 실시하였다. 결과: eSET군의 임상적 임신율, 진행 임신율 및 출산율 (각각 53.3%, 47.3% 및 44.9%)은 eDET군의 것들 (각각 60.7%, 54.6% 및 50.9%)보다 통계적으로 유의한 차이가 없었다. 그러나 착상률은 eSET군이 eDET군보다 통계적으로 유의하게 높았고 (각각 53.9%와 40.2%, p<0.001), 쌍태아의 임신율은 eSET군이 eDET군보다 유의하게 낮게 나타났다 (각각 1.1%와 32.3%, p<0.001). 또한, 잉여배아들을 유리화하여 보관하게 된 환자의 비율은 eDET군보다 eSET군에서 유의하게 높았을 뿐만 아니라 (각각 68.7%와 89.2%, p<0.001), 환자당 보관된 잉여배아의 수도 eSET군에서 eDET군에 비하여 유의하게 높게 나타났다 (각각 $3.2{\pm}2.6$과 $2.1{\pm}2.4$,p<0.001).결론: 채취당 임신율을 높이고 다태아의 임신에서 기인한 합병증 등을 줄이기 위해서는 내원한 첫 번째나 두 번째 IVF-ET 환자들 가운데 36세 미만이고 HCG를 투여한 당일 자궁내막의 두께가 8 mm이상이며 3일째에 우수한 배아가 하나만 있더라도 eDET보다 eSET를 실시함이 바람직하다고 생각된다. Objective: This study was performed to compare the clinical outcome of elective single embryo transfer (eSET) performed at the cleavage stage to that of elective double embryo transfer (eDET). Methods: Of the women less than 36 years old who visited Daegu Maria from January 2008 to April 2009, the only women (n=330) with more than 8 mm of endometrial thickness and at least one good quality embryo, who were treated with GnRH agonist long protocol, were included in this study. After information about complications that can arise by multiple embryo transfer, either eSET or eDET was conducted by their request (167 and 163, respectively).Results: The implantation rate of eSET group was significantly higher than that of eDET group (53.9% vs. 40.2%, p<0.01). The twin pregnancy rate of eSET group was significantly lower than that of eDET group (1.1% vs. 32.3%, p<0.001). However, there were no significant differences between two groups in the clinical pregnancy (53.3% vs. 60.7%, p=0.172), ongoing pregnancy (47.3% vs. 54.6%, p=0.185) and live birth rates (44.9% vs. 50.9%, p=0.275). The number of the surplus embryos which developed to the blastocyst stage and cryopreserved at that stage was significantly higher in eSET group than that of eDET group ($3.2{\pm}2.6$ vs. $2.1{\pm}2.4$, p<0.001). Conclusion: These results suggest that eSET should reduce significantly the multiple baby pregnancy without decreasing the whole pregnancy rate in women with less than 36 years old.
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인간 포배기 배아의 초자화 동결에 관한 연구: II. 초자화 동결이 포배기 배아의 착상 및 임신에 미치는 영향
김수희,이상원,이주희,강상민,오희정,이승민,이성구,윤혜균,윤산현,박세필,송해범,임진호,Kim, Su-Hee,Lee, Sang-Won,Lee, Ju-Hee,Kang, Sang-Min,Oh, Hee-Jeong,Lee, Seoung-Min,Lee, Seong-Goo,Yoon, Hye-Gyun,Yoon, San-Hyun,Park, Se-Pill,Song, Hai- 대한생식의학회 2000 Clinical and Experimental Reproductive Medicine Vol.27 No.1
Objective: This study was conducted to investigate the effect of vitrification on the implantation and the pregnancy of human blastocysts. Method: The transfer of the frozen-thawed blastocysts by the slow freezing or vitrification was performed between January 1998 and July 1999. The zygotes derives from IVF were cocultured with cumulus cells in YS medium containing 20% hFF for 5days. Two or three of the best balstocysts produced on day 5 were transferred into the uterus, and then supernumerary blastocysts were randomly divided into two groups. One was frozen by slow freezing and the other was frozen by vitrification method. The slow freezing procedure was performed in two steps (5% glycerol and 9% glycerol + 0.2 M sucrose for 10 min, respectively) using programmed freezer ($-2^{\circ}C$/min to $-7^{\circ}C$, manual seeding at $-7^{\circ}C$, $-0.3^{\circ}C$/min to $-38^{\circ}C$ and plunged into $LN_{2}$). The blastocysts frozen by slow freezing were thawed at $36^{\circ}C$ then removed glycerol in 7 steps. The vitrification procedure was performed in three steps (10% glycerol for 5 min, 10% glycerol + 20% ethylene glycol for 5 min, 25% glycerol + 25% ethylene glycol and directly $LN_{2}$ within 1 min). The blastocysts frozen by vitrification were thawed at $20^{\circ}C$ water then removed cryoprotectant in 3 steps. In each group, thawed blastocysts were cocultured with cumulus cells in YS medium containing 20% hFF for 18h and transferred into the uterus. The implantation rate was evaluated per transferred blastocysts and the pregnancy rate was evaluated per transfers. Results: The survival rate of vitrified group (74.5%) was higher than slow freezing group (68.0%), but not significant. When 98 thawed blastocysts of vitrification were transferred in 40 cycles, 19 pregnancies (clinical pregnancy rate; 47.5%) were established. One miscarriage occurred in the eighth week of pregnancy (ongoing pregnancy rate; 45.0%). 7 pregnancies were ongoing, 11 pregnancies went to term, and 16 healthy infants were born. The Implantation rate was 31.6%. These results were higher than those obtained by the slow freezing (clinical pregnancy rate; 40.3%, ongoing pregnancy rate; 32.5% and implantation rate; 25.3%), but not significant. Conclusion: Vitrification is a simple, quick and economical method when compared to slow freezing. It will be chosen as a good method of human embryo freezing in IVF-ET programs.
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정대율(Dae-Yul Jeong),강상민(Sang-Min Kang) 한국인터넷전자상거래학회 2004 인터넷전자상거래연구 Vol.4 No.2
Many e-Learning companies are incorporated for the last five years, but most of them are failed or merged by the other company. The main reasons are the absence of competitive strategies and recognition of critical success factors. There are many researches on the critical success factors of Information System OS) and Electronic Commerce(EC). We derived 51 e-Learning success factors from the previous IS and EC researches. We classified the success factors into five dimensions, ① contents management, ② learner management, ③ business strategy. ④organizational support and ability. ⑤ learning management system(LMS). We surveyed the perceived importance of the success factors from the managers of South Korea e-Learning companies. The paper proposed 14 success factors by the exploratory factor analysis. Each dimension has two or three factors which was interpreted by the grouped items definition. The rank of the factors was calculated, as result. system performance and convenience factor was ranked first, and<br/> contents differentiation was next. Finally. we suggested the strategic implications of the highly ranked factors for the e-Learning operation firms.
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자동차 정비공에서 발생한 수부 소지구 부위의 외상후 동정맥혈관종
남광우(Kwang Woo Nam),강상민(Sang Min Kang),신성진(Sung Jin Shin),서규범(Kyu Bum Seo) 대한정형외과학회 2013 대한정형외과학회지 Vol.48 No.2
동정맥혈관종은 주로 사지와 두피에서 발생하며, 여성과 아이들에게서 흔하게 보고되고 있다. 그러나 외상후 동정맥혈관종에 대한 보고는 매우 드물며, 신경학적 증상이 동반된 수부 소지구 부위에 발생한 외상후 동정맥혈관종에 대해서는 보고된 바가 없다. 이에 저자들은 반복적인 외상후 수부 소지구 부위에서 동정맥혈관종이 발생한 52세 남자 환자에서 수술적 제거술을 시행하고 좋은 결과를 얻었기에 문헌고찰과 함께 보고하고자 한다. Arteriovenous hemangiomas are found mainly in the limbs and scalp, and are common in women and children. However, there have been very limited reports concerning posttraumatic arteriovenous hemangioma, and none was reported in the medical literature regarding posttraumatic arteriovenous hemangioma of hypothenar eminence causing neurologic symptoms. We report a case of arteriovenous hemangioma of hypothenar eminence after recurrent trauma that was successfully treated by an excision of the mass and vein graft.
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우시오타니와타루 ( Wataru Ushiodani ),김창주 ( Chang Ju Kim ),강상민 ( Sang Min Kang ) 한국유통물류정책학회 2016 유통물류연구 Vol.3 No.2
본 연구의 목적은 전환기의 경영관리시스템(MCS)의 변화를 일본 기업의 복수 사례 분석을 통하여 고찰하는 것이다. 구체적으로 기업의 라이프 사이클에 있어서 호황기와 전환기의 변화가 기업의 MCS에 어떠한 영향을 미치는가를 검증한다. 그리고 기업이 시장환경 변화에 대처하는 MCS의 구축에 있어, 중간 관리자에게 요구되는 역할은 무엇인지 그 특징을 도한다. 연구대상은 버블경제의 붕괴이전에 창업한 기업이며, 기업 라이프사이클에 있어서 호황기와 전환기를 적어도 한번 이상을 경험 한 서로 다른 업종의 제조업 5개사를 선정했다. 본 연구에서는, 각 기업의 인터뷰 조사 내용과 함께 공개할 수 있는 범위의 2차 자료를 가공하여, 비교 분석한 연구 결과를 일반화하고 있다. 본 연구의 결과로서, 일본 기업의 MCS의 초점은 호황기와 전환기라는 기업 라이프사이클의 변화에 영향을 받으며, 특히 호황기에는 문화적요소가, 전환기에는 행동 관리적 요소가 중심적인 역할을 한다는 것이 증명되었다. 나아가 본 연구에서는, 일본 기업과 미국 기업의 MCS 특징의 차이를 확인할 수 있었다. 마지막으로, MCS를 통해 조직 목표를 달성하는데 있어서, 경영진과 종업원을 가교하는 중간 관리자의 리더십과 행동이 중요하다는 것을 확인할 수 있었다. The purpose of this study is to investigate management control systems at Japanese companies in a transition stage. Specifically, we explore how the locus of this management practice has been changed when a Japanese company faces lower performance in the decline stage, and investigate what type of leadership is required of middle-level managers in order to make such management practices feasible. We use multi-case interview methods to analyze five manufacturers which have experienced at least one decline stage of a firm`s lifecycle after experiencing a satisfactory growth stage. The results reveal that Japanese firms have changed the locus of their management control systems in order to respond to their stage of lifecycle. When Japanese companies increase performance in the growth stage, they direct, motivate, evaluate, and control their employees by focusing largely on culture-related aspects. This finding is consistent with previous research which examined American companies` management control systems. However, Japanese companies manage behavior-related aspects coupled with other aspects, including culture, which has become a major issue in particular, when these companies face lower performance in the decline stage. This finding is different from that of previous research, which revealed that American companies conduct results-oriented management control. In addition, we offer plausible evidence on how middle-level managers play a key role, linking top-level management and employees in such management practices in order to achieve firms` objectives and goals.
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이병두(Byung Doo Lee),김성용(Sung Yong Kim),윤호중(Ho Joong Youn),강상민(Sang Min Kang),서영광(Young Gwang Seo),김원(Won Kim),허승무(Seung Moo Heo) 위기관리 이론과 실천 2015 Crisisonomy Vol.11 No.12
본 연구에서는 소나무 낙엽, 굴참나무 낙엽과 소나무 낙엽 + 생엽, 생가지 등 세 가지 연소 조건에서 발생하는 유해물질의 종류와 양을 측정하였다. 측정 결과, 미세먼지의 경우 고농도로 방출되고 있어 호흡기의 건강영향에 대한 대비가 필요하다. 휘발성유기화합물에서는 벤젠 등이 일반 대기에 비해 높은 수준으로 발생하였다. 총수지산류가 영국 정부의 노출기준을 상회하는 수준으로 발생하였고, 포름알데히드 역시 단기간 기준을 초과하는 수준으로 발생하였다. 산류 중에서는 황산의 농도가 단기간 노출기준 대비 약 30% 수준까지 확인되었다. 이산화탄소의 농도는 실내 농도 수준과 비슷하고, 일산화탄소는 높게 검출되었으나 고용노동부의 노출기준 이하였다. 소나무 생엽, 생가지를 연소할 때 미세먼지와 화학물질를 포함한 다양한 유해물질들이 다른 2가지 경우보다 더 높은 농도로 발생하였다. 이러한 측정 자료들은 향후 산불 진화대원과 지역주민들의 안전 기준을 정립하는 기초 자료로 활용될 수 있다. The study measured the types and amount of hazard substances in three burning conditions: burning leaves of Pinus densiflora, leaves of Quercus variabilis Blume, and a combination of live leaves and live branches of Pinus densiflora. The result demonstrates the importance of securing the respiratory health system when a high level of fine particles was emitted. The level of emitted benzene was relatively high compared to that in atmosphere. The level of total resin acids exceeded the U.K. regulation level, with formaldehyde surpassing the recommended short-term level. Sulfuric acid was measured about 30 percent of the short-term exposure level. Carbon dioxide concentration was similar to indoor CO2 concentration, while carbon monoxide concentration was lower than the exposure level suggested by the Korean government. As for burning conditions, burning live leaves and branches of Pinus densiflora produced the highest concentration of various hazard substances including fine particles and chemicals.
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