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보기, 보양, 온리약의 전처치가 glutamate current에 미치는 영향
김창주,김연정,김현배,김이화,이충열,Kim, Chang-Ju,Kim, Youn-Jung,Kim, Hyun-Bae,Kim, Ee-Hwa,Lee, Choong-Yeol 대한동의생리학회 1999 동의생리학회지 Vol.14 No.2
The effects of Bogi, Boyang and Onri herbs on glutamte receptor, and the regulatory mechanism of cAMP-protein kinase on the ion currents activated by Bogi, Boyang and Onri herbs using nystatin-perforated patch clamp were investigated and the following results were obtained. Ginseng radix and Astragali radix, Cervi cornu and Boshniakiae herba, and Aconiti tuber and Zingiberis rhizoma were chosen as Bogi, Boyang and Onri herbs respectively. 1. The ion currents activated by $10^{-5}M$ of glycine were used as controls. The magnitudes of the ion currents by the above named herbs were as follows; Cervi cornu>Astragali radix>Aconiti tuber>Zingiberis rhizoma>Ginseng radix>Boshniakiae herba. 2. The magnitudes of the ion currents by $10^{-5}M$ of glutamate pre-treated with 0.01 mg/ml of Bogi, Boyang and Onri herbs were sharply decreased. 3. The activity of ion channels activated by Bogi herbs pre-treated with $10^{-7}M$ of staurosporin, an inhibitor of protein kinase, for thirty seconds was observed as the experiment proceeded. Staurosporin brought about dephosphorylation of ion channels. Hence, while the activity of ion channels activated by Ginseng radix was decreased, the activity of ion channels activated by Astragali radix was increased, as time went by. 4. The activity of ion channels activated by Boyang herbs pre-treated with $10^{-7}M$ of staurosporin, an inhibitor of protein kinase and an dephosphorylating agent of ion channels, for thirty seconds was investigated. While the activity of ion channels activated by Cervi cornu was increased, the activity of ion channels activated by Boshniakiae herba was initially increased then sharply decreased. 5, The activity of ion channels activated by Onri herbs pre-treated with $10^{-7}M$ of staurosporin, an inhibitor of protein kinase and an dephosphorylating agent of ion channels, for thirty seconds was investigated. While the activity of ion channels activated by Aconiti tuber was increased, that of ion channels activated by Zingiberis rhizomal sharply declined.
김창주,Kim, Chang-Ju 한국기계연구원 1986 기계연구원소보 Vol.16 No.-
엔지니어링 데이터로서 금속재료의 저주기 피로특성 규명은 중요한 의미를 가지며 이에 관한 연구는 1950년대 초부터 본격적으로 시작되었다고 볼 수 있다. 저주기 피로과정은 응력 반복수가 1-20,000회 정도에서 파괴가 일어나는 현상을 주 대상으로 하며 이의 이론적 설명을 위하여 Coffin 1) 과 Manson 2) 의 정리를 요약하여 인용하고자 한다.
Perennial ryegrass 의 파종비율을 달리한 혼파 목초지에 있어서 목초생장 및 식생구성비율의 계절적 변화
김창주,김동암 ( Chang Ju Kim,Dong Am Kim ) 한국축산학회 1977 한국축산학회지 Vol.19 No.3
This experiment was carried out to investigate seasonal variations in the plant growth and botanical composition of the mixture swards of orchardgrass/perennial ryegrass/Ladino clover sown at different seeding rates of perennial ryegrass. Five kinds of seeds mixture of orchardgrass 20 ㎏/㏊ Ladino clover 3 ㎏/㏊ added with 0 ㎏/㏊ (P-0), 5 ㎏/㏊(P-5), 10 ㎏/㏊(P-10), 20 ㎏/㏊(P-20) and 30 ㎏/㏊(P-30) of perennial ryegrass were sown in the experimental field of Kangwon National University on the 24th of April in 1972. The experimental mixture swards were cut once a month from June to October in the First harvest year (1972) and from April to October in the second harvest year (1973). The results obtained were summarized as follows: 1. Establishment ratio of orchardgrass and Ladino clover showed a tendency to drop as the seeding rate of perennial ryegrass rises. Orchardgrass and Ladino clover seemed to be oppressed already one month after the sowing by perennial ryegrass which was vigorous in early stage growth. 2. All the plants of the mixture shards had an inclination to show shorter plant length in spring and autumn, yet longer in summer. Perennial ryegrass showed comparatively little variation in the plant length throughout the growing period, while orchardgrass and Ladino clover marked large variation. 3. In the first harvest year, until the early summer the botanical composition ratio of perennial ryegrass marked 14.1% in P-5, 27.2% in P-10, 47.3% in P-20 and 63.7% in P-30 but after the midsummer the ratio dropped remarkably to 7.4%, 17.7%, 28.7% and 44.1% respectively. 4. Perennial ryegrass revealed poor summering and wintering record; it mostly disappeared after the midsummer of the second harvest year. 5. In the first harvest year, as seasons progressed from spring to autumn the ratio of perennial ryegrass in the botanical composition had a tendency to decrease in the plots sown under 10 ㎏/㏊ of perennial ryegrass but the ratio tended to increase in the plots sown more than 20 ㎏/㏊ of perennial ryegrass while the ratio of Ladino clover rised in every plots. 6. In the second harvest year, all through the growing seasons orchardgrass and Ladino clover maintained their botanical composition ration relatively equal except for the temporary dropping in orchardgrass` ratio in May and June and temporary rising in Ladino clover`s ratio in the same months. 7. Until the early summer of the second harvest year the botanical composition ratio inclined to drop in orchardgrass and Ladino clover and to rise in perennial ryegrass in proportion to increase in seeding rate of perennial ryegrass, but after that time difference of the botanical composition derived from the different seeding rates of perennial ryegrass was not noticed among the plots.