일측 질 폐쇄와 동측 신장무발생을 동반한 완전중격자궁에서 발생한 자궁질혈종

차선희(Sun Hee Cha),이현행(Hyun Haing Lee),김현철(Hyun Chul Kim),이미화(Mee Hwa Lee),김숙경(Suk Kyung Kim) 대한산부인과학회 2000 Obstetrics & Gynecology Science Vol.43 No.1

We report a case of a 13-year-old girl who was noted to have combined malformation of complete septate uterus, obstructed hemivagina and ipsilateral renal agenesis with complaints of dysmenorrhea. Hematometrocolpos was developed in the result of retained menstrual blood since menarche. This rare congenital anomaly is supposed to be derived from disorders of mesonephric and M llerian developement in embryogenesis of female genitouinary tract. An accurate preoperative diagnosis of this syndrome is critical because of the difference in therapeutic strategy and prognosis. Simple and definite treatment of the condition is excision of the obstructed vaginal septum with prompt exit of retained blood. We present here a interesting case of M llerian anomaly in attempt to alert gynecologist to the possible occurrence of such a malformation with a brief review of concerned literatures.

직교식 스테레오 비젼 시스템에서의 3차원 좌표 변환

윤희주 ( Hee-joo Yoon ),차선희 ( Sun-hee Cha ),차의영 ( Eui-young Cha ) 한국정보처리학회 2005 한국정보처리학회 학술대회논문집 Vol.12 No.1

본 시스템은 어항 속의 물고기 움직임을 추적하기 위해 직교식 스테레오 비젼 시스템(Othogonal Stereo Vision System)으로부터 동시에 독립된 영상을 획득하고 획득된 영상을 처리하여 좌표를 얻어내고 3차원 좌표로 생성해내는 시스템이다. 제안하는 방법은 크게 두 대의 카메라로부터 동시에 영상을 획득하는 방법과 획득된 영상에 대한 처리 및 물체 위치 검출, 그리고 3차원 좌표 생성으로 구성된다. Frame Grabber를 사용하여 초당 8-Frame의 두 개의 영상(정면영상, 상면영상)을 획득하며, 실시간으로 갱신하는 배경영상과의 차영상을 통하여 이동객체를 추출하고, Labeling을 이용하여 Clustering한 후, Cluster의 중심좌표를 검출한다. 검출된 각각의 좌표를 직선방정식을 이용하여 3차원 좌표보정을 수행하여 이동객체의 좌표를 생성한다.

기왕제왕절개반흔에 발생한 자궁외 임신의 Methotrexate 국소주입에 의한 치료 1례

이상희(Sang Hee Lee),김지혜(Jee Hye Kim),차선희(Sun Hee Cha) 대한산부인과학회 1999 Obstetrics & Gynecology Science Vol.42 No.8

Myometrial pregnancy developing in an previous cesarean section scar is the rarest of all ectopic pregnancy and provavly one of the most dangerous because of the risk of rupture and hemorrhage. For a young patient wanting to maintain her fertility, an earlier diagnosis and more conservative treatment are highly desirable. We present a case of an ectopic pregnancy embedded in the myometrium of a previous cesarean section scar in which the patient preserved her fertility through more noninvasive method, transvaginal ultrasound-guided Methotrexate injection.

연계점에서의 복소전력을 이용한 단독운전 판단기법

姜龍澈(Yong-Cheol Kang),車善熙(Sun-Hee Cha),張成一(Sung-Il Jang),姜海權(Hae-Gweon Kang),金容均(Yong-Gyun Kim),朴君哲(Goon-Cherl Park) 대한전기학회 2008 전기학회논문지 Vol.57 No.12

A large scale embedded generator or a micro-grid is usually interconnected to the grid through the dedicated line. Immediately after the removal of the grid supply, it must be disconnected and remain disconnected until the normal grid supplies are restored. This paper proposes an islanding detection algorithm based on complex power at the intertie. Complex power at the intertie delivered to the grid has a value depending on power flow during normal operation. When loss of mains occurs, complex power at the intertie moves to a value depending on the parameters of the dedicated line. The performance of the proposed algorithm was investigated under various operating and fault conditions. The proposed algorithm can detect an islanding operation even if no power is exchanged prior to loss of mains and discriminate the fault condition from islanding.

Methylenetetrahydrofolate Reductase(MTHFR) 유전자다형과 자연 유산아 발생의 관련성에 관한 연구

전익범,지승일,신승주,차선희,최동희,임동진,박상희,이수만,이상화,고정재,김남근,Jeon, Nick-Beom,Ji, Seung Il,Shin, Seung Joo,Cha, Sun Hee,Choi, Dong Hee,Yim, Dong Jin,Park, Sang Hee,Lee, Suman,Lee, Sang Hwa,Ko, Jung Jae,Kim, Nam Keun 대한생식의학회 2006 Clinical and Experimental Reproductive Medicine Vol.33 No.1

목 적: 본 연구는 methylenetetrahydrofolate reductase (MTHFR C677T와 A1298C) 유전자 돌연변이형이 자연유산아 발생의 원인 유전자로 작용하는지에 대해 알아보고자 시도하였다. 연구방법: 95명의 자연유산아 조직과 대조군으로 100명의 정상 소아의 혈액 그리고 449명의 정상 성인의 혈액을 채취하여 DNA를 분리하여 사용하였다. 유전자형은 분리된 DNA를 이용하여 중합효소 연쇄반응과 제한효소 절편다형 분석방법으로 결정하였다. 결 과: 자연유산아 그룹은 소아대조군에서 보다 MTHFR 677CC 형 (p=0.014)은 높게, 677CT형 (p=0.063)은 낮게 나타났다. 성인대조군과의 비교에서도 MTHFR 677CT 형의 빈도는 현저히 낮게 나타났다 (p=0.032). 그리고 MTHFR 677CC/1298AC 조합형 유전자의 경우 소아대조군 (p=0.034)과의 비교에서는 현저히 높은 빈도를 나타냈으나, 성인대조군 (p=0.063)과의 비교에서는 높은 경향성은 있었으나 통계학적으로 유의한 차이는 없었다. 결 론: MTHFR 677CC와 MTHFR 677CC/1298AC 유전자형은 자연유산아 발생의 위험인자일 가능성이 높으며, 지속적인 연구가 요구된다. Objectives : This study was performed to understand the influence of the methylenetetrahydrofolate reductase (MTHFR C677T and A1298C) genotypes on the spontaneously aborted embryos. Methods : DNA was extracted from tissue samples of 95 spontaneously aborted embryos and 100 samples of normal children randomly and 449 samples of normal adults were selected as the controls. MTHFR genotypes were determined by a polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) assay. Results : The aborted embryo group had higher frequency of MTHFR 677CC type (p=0.014) and lower 677CT type (p=0.063) than the controlled child group. The frequency of MTHFR 677CT type was drastically lower than that of controlled adult group (p=0.032). In the MTHFR C677T/A1298C combination, 677CC/1298AC genotype of the aborted embryo was significantly higher (p=0.034) than that of controlled child group, but it was not statistically significant in controlled adult group (p=0.063). Conclusion : MTHFR 677CC and MTHFR 677CC/1298AC genotypes may represent genetic markers for the risk of spontaneously aborted embryos at least in Koreans.

복강경하 난관복원수술 후 임신율에 관한 임상연구

이위현(Wee Hyun Lee),차선희(Sun Hee Cha),이미화(Mee Hwa Lee) 대한산부인과학회 1999 Obstetrics & Gynecology Science Vol.42 No.3

N/A Objective: Our purpose was to evaluate the pregnancy outcome and the advantages of laparoscopic tubal reanastomosis. Method; During 16 months, January 1996 to April 1997, thirty-two patient had underwent laparoscopic tubal reanastomosis in Pudang CHA General Hospital. The mean age of the patients was 36.1+-4.3 years(mean+-SD; range 26 to 47 years). Result: The intrauterine pregnancy rate of laparoscopic tubal reanastomosis was 72.4%(21/29). Data comparing laparoscopic procedure retrospectively to tubal reversal by laparotomy was also evaluated. The mean interval from operation to pregnancy was similar in the two groups (p=0.9). The operation time was sigoificantly longer for laparoscopy (215.3+-35.5 minutes) than for laparotomy(159.7+-52.3 minutes). Nevertheless, the intensity of postoperative pain was lower (p<0.05) in patient who underwent laparoscopy than in patient who underwent laparotomy. Also, the mean hospital stay (3.6+-2.3 days for laparoscopy, 6.1+-0.5 days for laparotomy) was shortened(p<0.05) after laparoscopy compared with laparotomy. Conclusion: Laparoscopic tubal reanastomosis may offer the benefits of lower postoperative pain and shorten recovery time in comparison with laparotomy. Therefore, considering the high pregnancy rate in minimal follow up period of 6 month, laparoscopic tubal reanastomosis could be an alternative procedure to microsurgical laparotomy in patients requesting reversal of sterilization.

청소년기에 발생하여 하부 생식기 폐색과 양측 난관 농양을 초래한 심한 소음순 유착

김미경 ( Mi Kyoung Kim ),김수현 ( Soo Hyun Kim ),차선희 ( Sun Hee Cha ),이미화 ( Mee Hwa Lee ) 대한산부인과학회 2009 Obstetrics & Gynecology Science Vol.52 No.10

Labial adhesions are extremely rare in adolescent and adult populations, because the etiology of this entity commonly relates to chronic vulvar inflammation or irritation, and is basically associated with low estrogen status. Although a few cases reported urinary retention resulting from severe labial adhesions, there is no report of labial adhesion that precipitates upper genital tract infection in prepubertal and postpubertal females. We present a rare case of severe labial adhesion and consequential lower genital tract obstruction that allegedly causing bilateral pyosalpinx in a 14-year-old adolescent girl who decisively denied sexual experience. The patient was successfully treated with surgical lysis of adhesion and administration of antibiotics.

조기난소부전과 관련된 자가면역질환에 대한 연구

남윤성 ( Yoon Sung Nam ),김남근 ( Nam Keun Kim ),이은혜 ( Eun Hye Lee ),차선희 ( Sun Hee Cha ),이정노 ( Jung No Lee ) 대한폐경학회 2001 대한폐경학회지 Vol.7 No.1

N/A Objectives : To report the autoimmune diseases associated with premature ovarian failure. Materials and Methods : For 55 patients of premature ovarian failure, the test for lupus anticoagulant, anticardiolipin antibody, antithyroglobulin antibody, antimicrosomal antibody, antinuclear antibody, rhematoid factor, calcium, phosphorus, vitamin B12, cortisol, glucose, and CBC were performed. Results : The ranged from 25 to 36 years and follicle stimulating hormone rose to the level between 42.1 - 93.7 ㎖U/mL. The incidence of autoimmune antibodies was 25%. The most common autoantibody was antithyroid antibodies(12 cases), and there were 3 cases if antinuclear antibody, 1 case of anticardiolipin antibody. Of 12 cases of positive antithyroid antibodies, there were 4 cases of positive antithyroglobulin antibody, 2 cases of antimicrosomal antibody, and the other 6 cases were found to have both antibodies. The function of thyroid gland was usually normal despite of positive antithyroid antibodies. There were 2 cases of Hashimoto`s thyroiditis, 1 case of mumps oophoritis, myasthenia gravis, antiphospholipid syndrome, respectively. Conclusions : Premature ovarian failure is associated with other autoimmune diseases in many cases. So the workup of autoantibodies should be included in the diagnosis and follow up of patient with premature ovarian failure.

히스테리시스 특성을 고려한 전압 변성기 오차 개선 방법

강용철(Yong-Cheol Kang),이병은(Byung-Eun Lee),박종민(Jong-Min Park),차선희(Sun-Hee Cha),장성일(Sung-Il Jang),김용균(Yong-Guen Kim) 대한전기학회 2006 대한전기학회 학술대회 논문집 Vol.2006 No.7

Voltage Transformer is used to transform high voltage into low voltage to input signal of protection relay. Most of the Voltage Transformers use the iron core which maximizes the flux linkage. The ratio of the Voltage Transformer depends on the transformer turns ratio. The current which flows in the Voltage Transformer has non-linear characteristic caused by hysteresis of the iron core, it causes a voltage loss in the winding impedances which makes measurement errors. This paper describes an error compensation method considering hysteresis characteristic. The proposed compensation method improves error by calculating the primary current from the exciting current of the hysteresis loop in the Voltage Transformer, compensating the voltage loss.

시험관아기로 임신된 쌍태아 중 일측 태아에서 위양성 Acetylcholinesterase를 보인 임신 1례

은미나 ( Mi Na Eun ),김현쳘 ( Hyeon Chul Kim ),신승주 ( Seoung Ju Shin ),차선희 ( Sun Hee Cha ),김낙근 ( Nack Keun Kim ),김지연 ( Ji Yoeun Kim ),정상근 ( Sang Geun Jung ),강석호 ( Suk Ho Kang ),김수진 ( Su Jin Kim ),정은호 ( Eun H 대한주산의학회 2003 Perinatology Vol.14 No.3

임신 중반기 여성에서 개방성 신경관 결손증의 선별검사로서 모체 혈청내 알파태아단백이 이용되고 있다. 모체 혈청 AFP의 증가는 임신 주수의 과소추정이나 신경관 결손증 외에도 태아의 선천성 신증, 식도나 장폐쇄와같은 소화기 질환, 복부결손등의 선천성 기형과 연관이 있으며 이외에도 저체중 출생아, 양수감소증, 태아 사망 및 염색체이상등의 경우에서도 증가하게 된다. 이 경우 초음파 검사를 통해 제태 연령을 재측정하거나 기형 여부, 다태 임신, 태아사망 등을 감별해야 한다. 신경관 결손증이 의심되거나 초음파가 비진단적인 경우, 양수천자를 실시하여 양수내 AFP를 검사하게 되는데, 이 역시 증가한 경우에는 AFP 증가의 위양성의 가능성을 배재하기 위해 Acetylcholinesterase를 측정하는 것이 도움이 된다. AChE 검사는 신경관 결손증을 진단하는데 98% 이상의 검출율을 보이고 있으며 위양성율은 0.14% 정도로 보고 되고 있는데 태아나 모체의 혈액이 감염된 경우 위양성율이 증가된다. 본원에서는 난자 세포질내 정자 주입술(ICSI) 및 접합자 난관내 이식술(ZIFT)을 통해 임신 된 쌍태임신에서 양수검사를 시행하여 일측 태아에서 AFP가 증가하였으며 AChE 또한 양성 소견 보여표적 초음파를 시행하였고, 이상 소견이 보이지 않아 유전상담과 반복 초음파 시행하면서 만삭까지 임신을 유지시켜제왕절개로 정상의 쌍태아를 분만한 예를 경험하였기에 간단한 문헌 고찰과 함께 보고하는 바이다. Maternal serum alpha-fetoprotein(MSAFP) has been a world wide screening test for open neural the tube defect. But elevation of MSAFP is related to not only neural tube defect, but also incorrect gestational age, congenital anomalies such as congenital nephrosis, esophageal & intestinal obstruction, low birth weight, oligohydroamnios, fetal death and chromosomal anomalies. If MSAFP is elevated, gestational age, congenital anomalies such as neural tube defect, multiple pregnancy and fetal death must be evaluated by ultrasound. When the ultrasound is nondiagnostic, amniotic fluid AFP(AFAFP) levels are measured and if AFAFP is elevated, presence or absence of aetylchoineststarase(AChE) is determined to rule out the false positive of amniotic AFP. Amniotic AChE test yielded detection rate of open spina bifida of 99%, 98% for anecephaly and a false-positive rate of 0.34%. We report a case with elevated AFAFP and positive amniotic AChE result in one fetus of the twin pregnancy conceived by ICSI and ZIFT, but in which targeted ultrasound findings were normal, maintained the pregnancy to term and normal twin was delivered by elective cesarean section.