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면접조사를 통한 초등학생의 영양교육 실태 및 실천도 조사
오유진,이영미,김정현,안홍석,김정원,박혜련,서정숙,김경원,권오란,박혜경,이은주,성현이 대한지역사회영양학회 2008 대한지역사회영양학회지 Vol.13 No.4
This study investigated the experience and practice of elementary school students on nutrition education. The data were collected from 217 male and female students attending 5-6th grade elementary schools in Seoul and Kyunggi-Do from March to June 2007, interviewing face to face by a nutrition teacher and 3 interns of a nutrition teacher. The results were as follows: 86.5% of the subjects learned about ‘Table etiquette’, ‘Reasons for eating fruits and vegetables’ (78.7%), ‘Food waste and environment’ (72.3%), ‘Healthy snacks’ (55.7%), ‘Food sanitation’ (52.3%), ‘Food culture of foreign countries’ (48.1%). Nutrition education experience was significantly different by gender. A total of 43.5% boys responded that they never learned about ‘basic food preperation’ (p < 0.01). They had learned ‘Nutrients for body’ and ‘Food waste and environment’ in school, ‘Healthy weight loss’, ‘Food culture of foreign countries’, ‘Food circulation’ on television, Most content (‘Table etiquette’, ‘Simple cooking’, ‘Food sanitati n’, ‘Eating behaviors for health’, ‘Reasons for eating fruits and vegetables’, ‘Healthy snacks’) was learned from parents. The practice after nutrition education was higher in ‘Table etiquette’ (2.14), ‘Eating fruits and vegetables’ (2.07) than others compared with education experience. The most reason of non-practice on nutrition information was ‘Troublesome’. In ‘Nutrients for body’, a boy answered ‘Difficult for practice’ 20.0%, a girl answered ‘Difficult to understand’ 32.6%, showing a significant difference between the gender groups (p < 0.001). They remembered the ‘Nutrients for body’ (49.6%), ‘Food sanitation’ (44.5%) because of ‘important content’,‘Basic food preparation’ (40.6%), ‘Food culture of foreign countries’ (36.3%) because of ‘interesting content’, ‘Healthy weight loss’ (52.0%), ‘Eating behavior for health’ (44.5%) and ‘Healthy snacks’ (33.7%) because of ‘need for my health’.
제 1형 신경섬유종증 환자에서 발생한 위장관 간질종양 1예
원경준,이준,변유미,조민근,한경택,김원,홍란,임성철,김경종,김영대,박찬국,김만우 朝鮮大學校 附設 醫學硏究所 2007 The Medical Journal of Chosun University Vol.32 No.2
Gastrointestinal stromal tumor (GIST) is the most common non-epithelial neoplasm arising in the gastrointestinal tract, but this tumor is rarely seen in association with type l neurofibromatosis (NFl) Generally, the majority of GISTs are isolated neoplasm and they are sporadically found in the stomach, but the GISTs in NFl patients are usually multiple and usually found in the small intestine. We report a case of multiple GISTs in the jejunum of a 63-year-old woman diagnosed as NFl accompanied by complication of gastrointestinal bleeding, In this case, Patient had multiple cafe-au lait spots and neurofibroma on skin and had freckling on axilla and groin, and then, we made a diagnosis of NFl. Gastrointestinal bleeding is controlled by resection of multiple GISTs. Generally, only 3-5% of all gastrointestinal bleeding comes from the small bowel. Causes of small intestinal bleeding are angiodysplasia, neoplasm, NSAIDs induced ulcer etc. but, If patients have NFl accompanied by complication of gastrointestinal bleeding, GISTs on small bowel must be considered.
Prevalence and antimicrobial resistance of Clostridium difficile isolated from Korean native cattle
Yu-Ran Lee(Yu-Ran Lee),Jong Wan Kim(Jong Wan Kim),Chung Hyun Kim(Chung Hyun Kim),Bun Seung Jo(Bun Seung Jo),Hyun Mi Kim(Hyun Mi Kim),ByungJae So(ByungJae So),Ha-Young Kim(Ha-Young Kim) 한국예방수의학회 2017 한국예방수의학회 학술대회자료집 Vol.2017 No.-
Observation of the Ring-Puckering Vibrational Mode in Thietane Cation
Lee, Yu Ran,Park, Chung Bin,Hwang, Jiye,Sung, Bong June,Kim, Hong Lae,Kwon, Chan Ho American Chemical Society 2017 The Journal of physical chemistry A Vol.121 No.5
<P>We have measured the high-resolution vibrational spectra of a thietane (trimethylene sulfide) cation in the gas phase by employing the vacuum ultraviolet mass analyzed threshold ionization (VUV-MATI) spectroscopic technique. Peaks in the low frequency region of the observed MATI spectrum of thietane originate from a progression of the ring-puckering vibrational mode (typical in small heterocyclic molecules), which is successfully reproduced by quantum-chemical calculations with 1D symmetric double-well potentials along the ring puckering coordinates on both the S-0 and D-0 states, the ground electronic states of neutral and cation of thietane, respectively. The values of the interconversion barrier and the ring-puckering angle on the S-0 state, the parameters used for the quantum-chemical calculations, were assumed to be 274 cm(-1) and 26 degrees. The barrier and the angle on the D-0 state, however, are found to be 48.0 cm(-1) and 18.2 degrees, respectively, where such small barrier height and puckering angle for the cation suggest that the conformation of thietane cation on the D-0 state should be more planar-than that of the thietane neutral.</P>
Occurrence and genetic diversity of <i>Blastocystis</i> in Korean cattle
Lee, Haeseung,Lee, Seung-Hun,Seo, Min-Goo,Kim, Ha-Young,Kim, Jong Wan,Lee, Yu-Ran,Kim, Jong Ho,Kwon, Oh-Deog,Kwak, Dongmi Elsevier 2018 Veterinary parasitology Vol.258 No.-
<P><B>Abstract</B></P> <P> <I>Blastocystis</I> is one of the most commonly detected intestinal protozoan parasites worldwide and has been found in humans and other animals. Therefore, many countries have actively researched this parasite. However, to our knowledge, no study of <I>Blastocystis</I> has been conducted in Korea. Therefore, we conducted a study of the current status of <I>Blastocystis</I> infection in domestic cattle, the various genotypes involved, and its zoonotic potential through a phylogenetic comparison with subtypes found in other studies. The feces of cattle were randomly collected throughout Korea; basic information, including collection date, sex, and cattle type was recorded, and DNA extraction, PCR, and phylogenetic analyses were performed. A total of 1,512 fecal samples were tested. The 101 <I>Blastocystis</I>-positive samples were obtained, yielding an approximate infection rate of 6.7%. Differences in age, cattle type, fecal type, and season were statistically significant between <I>Blastocystis</I>-positive and -negative cattle. In this study, four subtypes of <I>Blastocystis</I> (ST1, ST5, ST10, and ST14) were confirmed by phylogenetic analysis. ST1 and ST5 are potential zoonotic subtypes, therefore the possibility of zoonotic transmission cannot be ignored. Further research and clarification of the infection and transmission patterns of <I>Blastocystis</I> are warranted.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Fecal samples from Korean domestic cattle were collected for <I>Blastocystis</I> testing. </LI> <LI> Cattle age, breed, fecal type, and season influenced infection rates. </LI> <LI> Phylogenetic analysis confirmed the presence of subtypes ST1, ST5, ST10, and ST14. </LI> <LI> Zoonotic subtypes were detected, suggesting the risk of zoonotic transmission. </LI> </UL> </P>
( Yu Ran Park ),( Yong-man Kim ),( Shin Wha Lee ),( Ha Young Lee ),( Gun Eui Lee ),( Jong-eun Lee ),( Young-tak Kim ) 대한산부인과학회 2018 Obstetrics & Gynecology Science Vol.61 No.3
Objective Circulating cell-free tumor DNA (cfDNA) is the DNA released by apoptotic and necrotic cells of the primary tumor into the blood during the period of tumor development. The cfDNA reflects the genetic and epigenetic alterations of the original tumor. TP53 mutations are a defining feature of high-grade serous ovarian carcinoma. We optimized the methods for detecting TP53 mutations in cfDNA from blood samples. We confirmed the correlation of TP53 mutation in primary ovarian cancer tissue and it in cfDNA using digital polymerase chain reaction (dPCR). Methods We found 12 frequent mutation sites in TP53 using The Cancer Genome Atlas and Catalogue of Somatic Mutations in Cancer data and manufactured 12 primers. The mutations in tissues were evaluated in fresh-frozen tissue (FFT) and formalin-fixed paraffin-embedded tissue (FFPET). We performed a prospective analysis of serial plasma samples collected from 4 patients before debulking surgery. We extracted cfDNA and calculated its concentration in blood. dPCR was used to analyze TP53 mutations in cfDNA, and we compared TP53 mutations in ovarian cancer tissue with those in cfDNA. Results Ten primers out of 12 detected the presence of TP53 mutations in FFT, FFPET, and cfDNA. In FFT and FFPET tissue, there were no significant differences. The average cfDNA concentration was 2.12±0.59 ng/mL. We also confirmed that mutations of cfDNA and those of FFT were all in R282W site. Conclusion This study developed detection methods for TP53 mutations in cfDNA in ovarian cancer patients using dPCR. The results demonstrated that there are the same TP53 mutations in both ovarian cancer tissue and cfDNA.
Lee Yu Ran,Kwon Chan Ho 대한화학회 2022 Bulletin of the Korean Chemical Society Vol.43 No.5
The conformational structure of cyclopentanone (CP) and the photoionization dynamics of the corresponding conformer were investigated using the highresolution vacuum ultraviolet mass-analyzed threshold ionization (MATI) spectroscopic technique. To identify the conformer corresponding to the measured MATI spectrum, the potential energy surfaces associated with the twisting and carbonyl wagging motions in the S0 and D0 states were constructed at the B3LYP/cc-pVTZ level, where the twisted conformer in both states corresponded to the global minimum. Furthermore, the Franck–Condon fitting indicated that the cationic conformer had a warped twisted C1 symmetry rather than C2 symmetry. This implies that the ionization-induced ring distortion can be principally attributed to the removal of an electron from the highest occupied molecular orbital, which consists of the nonbonding orbital of the oxygen atom in the carbonyl group interacting with the σ orbitals in the ring of the twisted CP conformer.
Surface-Enhanced Raman Scattering and DFT Study of 4,4'-Biphenyldithiol on Silver Surface
Yu Ran Lee,김명수,권찬호 대한화학회 2013 Bulletin of the Korean Chemical Society Vol.34 No.2
Surfaced-enhanced Raman scattering (SERS) of 4,4'-biphenyldithiol (BPDT) has been investigated at a silver island film. Ordinary Raman (OR) spectra of neat sample in solid state and in basic solution have also been taken for comparison. The spectral feature in the SERS spectrum was similar to that for the OR spectrum in basic solution, except for the broadening of ring stretching bands indicative of the presence of surface-phenyl ring π interaction. In contrast, only absence of the C-H stretching band with very small Raman scattering crosssection seemed not pertinent in judging the definitive orientation of molecule. The observed vibrational bands in the SERS spectrum have been assigned by referring to the normal modes and wavenumbers from density functional theory (DFT) calculations of the simple model as 4,4'-biphenyldithiolates bound to two Ag atoms at the both ends. Excellent agreement between the experimental and the calculated results was achieved, which is remarkable considering the level of theory applied.