데빅병 치료에 사용한 Interferon β-1b의 부작용 1예

김정미,조은경,조정선,최용석,한영수,한정호,김두응,최진영 건국대학교 의과학연구소 2004 건국의과학학술지 Vol.14 No.-

A 63 year-old woman who had diagnosis of multiple sclerosis complaining left hemiparesis and fluctuating decreased visual acuity in her right eye and abnormal findings in pattern shift visual evoked potentials(PSVEPs) and on T2 weighted MR scanning. We treated her subcutaneously with 250μg interferon (3-lb(ITFß -lb) every other day. There were detected pancytopenia, skin rash, and abnormal liver function test seven days after the therapy. In spite of reducing the dose of interferon injection, abnormal laboratory findings were not returned to normal. Dose adjustment of interferon-I3 for body weight or race, may be helpful to reduce the side effects.

흔치않은 대상포진 치험 2예 : 비전형적 부위와 다른 부위로 재발한 예 Unusal Dermatome and Recurs Other Dermatome

김정미,조은경,조정선,최용석,한영수,한정호,김두응,최진영 건국대학교 의과학연구소 2004 건국의과학학술지 Vol.14 No.-

Herpes zoster is well known as an acute, self-limited disease of unilateral sensory dermatome caused by varicella-zoster virus and characterized by grouped vesicular skin eruption and pain over several dermatomes as well as single. This virus usually affects the thoracic dermatome and there are a few reports that this virus involves lower lumbar or sacral area, and recurrent cases. We experienced 2 cases that zoster virus involved L4 or S2 dermatome and left typical skin lesions, of which one was a recurrent case involving different dermatome at an interval of 8 years and the other was a rare case involving sacral dermatome.

폐결핵의 조기진단에 있어서 이중중합효소연쇄반응법의 유용성

조성란,최영진,김용훈,이철세,김영창,김휘준 순천향의학연구소 1998 Journal of Soonchunhyang Medical Science Vol.4 No.2

Background: Pulmonary tuberculosis is a great public health problem in Korea. Early detection of Mycobacterium tuberculosis (M. tuberculosis) in clinical samples becomes more and more important in the control of tuberculosis. Recently, molecular methods have been applied to early detection of M. tuberculosis. Methods: To elucidate the effectiveness of nested polymerase chain reaction (PCR) in early diagnosis of pulmonary tuberculosis, we peformed Acid-fast bacilli (AFB) stain, AFB culture, and nested PCR on 84 sputa. Results: 8 (9.5%) specimens were positive by AFB stain, 17 (20.2%) by AFB culture, and 15 (17.9%) by nested PCR. Using AFB culture as standard method, the sensitivity of AFB stain and nested PCR was 47.1% and 82.4%, respectively. The specificity of AFB stain and nested PCR was 100% and 98.5%, respectively. Conclusions: Nested PCR was more sensitive than AFB stain and had shorter processing time(24-48hrs) than AFB culture. So it may be effective to use nested PCR in order to detect M. tuberculosis when AFB smear Is negative.

근관장 측정시 구내 디지털 방사선 시스템인 Digora System의 정확도에 관한 연구

한상욱,홍찬의,조용범 大韓齒科保存學會 1997 Restorative Dentistry & Endodontics Vol.22 No.1

뿜칠시공에 의한 단면복구재의 시공성 및 공학적 특성에 관한 실험적 연구

조봉석,김영선,장재봉,김용로,김경덕,김무한 대한건축학회 2004 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.24 No.1

These days, serious concerns of reinforced concrete have been raised recently over steel-bar corrosion, cracking, the deterioration of durability and structural stress resistance and so on, all due to the effects of exterior factors. Such being the case, in domestic, various repair materials and method systems to keep up with these reinforced concrete deteriorated due to salt damage, carbonation, chemical decay et. developed and applied. However, on-site quality control of various repair materials and method systems isn't achieved desirably because it is depend completely on a men of experience' opinions above all else regardless of various on - site environments. In this background, mock up test with due regard to real on-site environments was performed to secure fundamental data for establishment of desirable on-site quality control. Mock up test using repair mortar analyzed from angles of construction methods, mechanical spraying pressures, W 1M. Construction methods were designed manpower method and spraying method, spraying pressures were designed 32, 42, 52 psi, W/M were designed 14.4, 15.4, 16.4 %. And compressive strength, Chloride ion diffusion coefficient, bond strength, SEM of mock up test specimens were evaluated. In conclusion, we confirmed excellency of mechanical spraying pressures, fined extremely excellency of condition of spraying pressure 42 ps, W/M 14.4% within this study. therefore the results of this study will be useful to provide fundamental data for establishment of desirable on-site quality control.

强靭鑄鐵의 熔接性에 關한 硏究

曺東震,韓俊澤,劉憲一,朴龍鎭,金錫胤,慶在浩 弘益大學校 1974 弘大論叢 Vol.6 No.-

The matrix of ductile cast iron are welded by pre-heating it at 300℃ in the room temperature. Through the mechanical, non-desbructive testing and analysis of the composition. the possibility if arc welding of ductile cast iron are studied as follows; 1. L electrode is the best among them in weldability, impact value and machinability. The next is LB electrode followed by S electrode. C electrode is last. However, the tensile strength showed in the following order: LB, S, L, C. 2. LB, S, L, C, all are available for the welding of cast iron. 3. The above experiment showed that L and LB are good in general. In addition LB is low in price, we therefore prospect that it will be widely used as the electrode for cast iron.

근관내 여러 조건에서의 ROOT ZX 전자근관장 측정기의 정확성에 관한 연구

조용범,홍한표,홍찬의 단국대학교 치의학연구소 1994 논문집 Vol.6 No.1

The technique of electronic working length determination has gained considerable popularity among both endodontists and general dentist. Recently, the Root ZX(J.Morita Corp., Tokyo, Japan) has been developed with unique electronic features that are claimed to maintain the instrument's accuracy regardless of canal condition. The purpose of this study is to compare the accuracy of the Root ZX with estimates of actual canal length, in vitro model and in vivo under the various condition. 1. The experiment in vitro model 50 extracted, single-rooted and single-canaled, teeth with mature apices were selected. The extirpated teeth were placed in a saline-soaked Oasis, and measured with Root ZX according to manufacturer's instruction in the dried canal and saline-irrigated canal. The teeth were then removed from the model and the actual canal length was measured. The values of canal length in each conditions were used for evaluating the results. 2. In vivo study 15 teeth which destined for extraction were selected. Once access was gained, the canals were irrigated using 5.25% sodium hypochlorite and were not dried prior to insertion of the measurement file. Once the Root ZX indicated the C-D junction, self-curing resin was injected into the canal. The tooth was extracted and ground with a bur and Soflex disk. This was done until the terminus of the file and the root was revealed. The distance from the end of the file to the foramen(major diameter) was measure, and evaluated. The results were as follows: 1. In vitro study(A/B : difference between A and B) 1). The mean values of acutal length/dried canal length and actual length/saline irrigated canal length were 0.528㎜, and 0.525㎜ respectively. There is no significant difference between the means of acutal length/dried canal length and actual length/saline irrigated canal length. 2). Root ZX could locate the C-D junction at the point of 0.5㎜ inside of major foramen, in both dried canal and saline-irrigated canal. 2. In vivo study 1). Root ZX could locate the the C-D junction at the point of 0.5㎜ coronal to the major foramen in presence of 5.25% NaOCl. 2). Root Zx located a point that was perceived to be the apical constriction. The majority of file tip experimented were within the canal, not extended beyond the major foramen.

근관내 여러 조건에서의 ROOT ZX 전자근관장 측정기의 정확성에 관한 연구

조용범,홍한표,홍찬의 단국대학교 치의학연구소 1994 단국대치의학연구소논문집 Vol.6 No.1

뇌종양의 악성도 판정을 위한 분열기 세포측정에 관한 연구

한용표,변진수,허철,홍순기,김헌주,조미연,정순희,김호근 대한신경외과학회 1992 Journal of Korean neurosurgical society Vol.21 No.11

Tissue markers of cellular proliferation have been utilized as prognostic indicators in tumors of the central nervous system. Nucleolar organizer regions represent transcriptionally active sites of ribosomal deoxyribonucleic acid and can be identified by a simple argyrophilic technique. The authors describe a standardized approach to the assessment of these argyrophilic nucleolar organizer regions(AgNORs) in 25 astrocytomas(including 6 glioblastomas), 6 oligodendrogliomas and 1 xanthochromic astrocytoma, which were also estimated in association with 2-year survival post-operatively. Appropriate sections were silver stained and AgNORs were counted in 1000 cells. In cases of astrocytoma, the mean AgNORs/cell count of group survived more than 2 years after operation was significantly different from that survived less than 2 years : 1.93±1.13 vs. ≥ 4.79±3.90. And the mean AgNORs/cell count was 1.53±0.32 in low grade astrocytoma. 2.03±0.59 in grade Ⅲ astrocytoma, and ≥6.64±3.77 in grade Ⅳ astrocytoma. Among the patients with the same grade astrocytoma, the mean AgNORs/cell count was lower in the cases of long survival rather than short survival. The assessment of AgNORs can be easily performed by any surgical pathology laboratory without specialized equipment. It may be used as a valuable and independent prognosticator of biological behavior in cases of astrocytoma.

복합열화환경하에서의 중성화 및 염화물이온 확산특성이 철근부식에 미치는 영향에 관한 실험적 연구

조봉석,장재봉,김재환,김용로,권영진,김무한 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.2

It is recognized that reinforcement corrosion is the main distress behind the present concern regarding concrete durability. In this study, to confirm corrosion of reinforced concrete due to permeability of carbonation and chloride ion affected by thickness of cover, kinds of surface coating, measured electric potential, ratio of corrosion area, weight reduction, corrosion velocity of steel bar under environment of complex deterioration. The results showed that an increase in age also decreases Carbonation velocity coefficients and increases Chloride ion diffusion coefficients. As well, an increase in age also increases corrosion of reinforcement due to permeability of carbonation and chloride ion. Corrosion of reinforcement by thickness of cover is superior to 10mm thick than 20mm thick. It showed that an increase in thickness of cover prevent steel bar from deteriorating due to permeability of carbonation and chloride ion. The results of this study showed that corrosion velocity was affected by thickness of cover, kinds of surface coating. data on the development of corrosion velocity made with none, organic B, organic A, inorganic B. and inorganic A is shown.