<tex> $ \phi $</tex> photoproduction on the proton at <tex> $ E_{\gamma }=1.5\hbox{--}2.9\;\mathrm{GeV}$</tex>

Mizutani, K.,Niiyama, M.,Nakano, T.,Yosoi, M.,Nozawa, Y.,Ahn, D. S.,Ahn, J. K.,Chang, W. C.,Chen, J. Y.,Daté,, S.,Gohn, W.,Hamano, H.,Hashimoto, T.,Hicks, K.,Hiraiwa, T.,Hotta, T.,Hwang, S. H.,I American Physical Society 2017 Physical Review C Vol.96 No.6

<P>Differential cross sections at t = t(min) and decay asymmetries for the gamma p -> phi p reaction have been measured using linearly polarized photons in the range 1.5 to 2.9 GeV. These cross sections were used to determine the Pomeron strength factor. The cross sections and decay asymmetries are consistently described by the t-channel Pomeron and pseudoscalar exchange model in the E-gamma region above 2.37 GeV. In the lower energy region, an excess over the model prediction is observed in the energy dependence of the differential cross sections at t = t(min). This observation suggests that additional processes or interference effects between Pomeron exchange and other processes appear near the threshold region.</P>

Photoproduction of <tex> $ \Uplambda $</tex> and <tex> $ \Upsigma ^{0}$</tex> hyperons off protons with linearly polarized photons at <tex> $ E_{\gamma }=1.5\hbox{--}3.0$</tex> GeV

Shiu, S. H.,Kohri, H.,Chang, W. C.,Ahn, D. S.,Ahn, J. K.,Chen, J. Y.,Daté,, S.,Ejiri, H.,Fujimura, H.,Fujiwara, M.,Fukui, S.,Gohn, W.,Hicks, K.,Hotta, T.,Hwang, S. H.,Imai, K.,Ishikawa, T.,Joo, American Physical Society 2018 Physical Review C Vol.97 No.1

<P>We report the measurement of the gamma p -> K+Lambda and gamma p -> K+Sigma(0) reactions at SPring-8. The differential cross sections and photon-beam asymmetries are measured at forward K+ production angles using linearly polarized tagged-photon beams in the range of E-gamma = 1.5-3.0 GeV. With increasing photon energy, the cross sections for both gamma p -> K+Lambda and gamma p -> K+Sigma(0) reactions decrease slowly. Distinct narrow structures in the production cross section have not been found at E gamma = 1.5-3.0 GeV. The forward peaking in the angular distributions of cross sections, a characteristic feature of t-channel exchange, is observed for the production of Lambda in the whole observed energy range. A lack of similar feature for Sigma(0) production reflects a less dominant role of t-channel contribution in this channel. The photon-beam asymmetries remain positive for both reactions, suggesting the dominance of K* exchange in the t channel. These asymmetries increase gradually with the photon energy, and have a maximum value of +0.6 for both reactions. Comparison with theoretical predictions based on the Regge trajectory in the t channel and the contributions of nucleon resonances indicates the major role of t-channel contributions as well as non-negligible effects of nucleon resonances in accounting for the reaction mechanism of hyperon photoproduction in this photon energy regime.</P>

A Molecular Dynamics Study on the Liquid - Amorphous - Crystalline Transition in a Lennard - Jonesian FCC System : 1. Bulk Crystal

Chang, H . K .,Kim, S . G .,Cheong, B .,Kim, W . M .,Chung, M .,Lee, T . S .,Lee, J . K . 대한금속재료학회(대한금속학회) 1998 METALS AND MATERIALS International Vol.4 No.6

Constant-pressure molecular dynamics simulations are carried out to study the liquid-amorphous-crystalline transition behavior in a model system composed of 500 Leonard-Jones particles under three-dimensional periodic boundary conditions. The critical quenching rate (CQR) for amorphization, i.e., the minimum rate above which no crystallization occurs on quenching, is found to be about 5.52 × 10^(12) K/s for a one-component, unary system. For lower quenching rates, the amorphous phase transforms to a crystalline phase with 0.30.5 of the melting point as the transition temperature. A binary system with a misfit in atomic size shows a smaller CQR, while a system with a higher bond strength for solute atoms requires a greater CQR. A crystallizakion behavior of an amorphous phase on repeating is also studied. Its crystallization temperature depends on the history: the higher the quenching rate for amorphization, the higher the crystallization temperature.

韓國人의 風疹 바이러스 血球凝集抑制抗體調査

Patwory, K.M.,金慶浩,徐俊錫,張起峰,鄭泰和 대한감염학회 1972 감염 Vol.4 No.1

The Hemagglutination-Inhibition (H-I) antibodies against rubella virus among Korean in 1972 were studied. The H-I antibody possess rate and antibody titers by age group and by area were analyzed. The data in Table's 1,2 and 3 summarize the results of H-I testing of 160 serum specimens. Age group 16~20 and 31~40 gives somewhat higher positiveness than the other age group. The age group 1 year has the lowest positivity. This interaction may be also significant due to a certain extent of different type of titers with titer 1 : 10 producing the highest number of positiveness and specifically with the age group of 11~15 and 21~30. The rural and urban areas people do not seem to have differences in terms of their titer positiveness and same is true in their interaction with age titer revealing on insignificant test. Therefore, in summary we conclude 1. The titers differ significantly in producing positiveness. Titer 1 :10 has the highest of producing such with very little of 1 : 320 and 1 : 640. 2. In general the age groups differ in terms of positiveness by titer but the degree of positiveness do not differ amongst tested population over 16 year of age groups very significantly. Therefore, the effect of titers beyond this age group population would be of similar magnitude. 3. The interaction between titer and age group seem to have a very strong impact on "positiveness" revealing the fact that individual aged will always bear significant variation in positiveness. 4. No significant variation in terms of positivencess could be observed amongst the rural and urban population from this experimental observation and same could be said about their being rural or urban with age or titer.

Safety assessment of trans-tympanic photobiomodulation

Moon, T. H.,Lee, M. Y.,Jung, J. Y.,Ahn, J. C.,Chang, S. Y.,Chung, P. S.,Rhee, C. K.,Kim, Y. H.,Suh, M. W. Springer Science + Business Media 2016 Lasers in medical science Vol.31 No.2

<P>We evaluated functional and morphological changes after trans-tympanic laser application using several different powers of photobiomodulation (PBM). The left (L) ears of 17 rats were irradiated for 30 min daily over 14 days using a power density of 909.1 (group A, 5040 J), 1136.4 (group B, 6300 J), and 1363.6 (group C, 7560 J) mW/cm(2). The right (N) ears served as controls. The safety of PBM was determined by endoscopic findings, auditory brainstem response (ABR) thresholds, and histological images of hair cells using confocal microscopy, and light microscopic images of the external auditory canal (EAC) and tympanic membrane (TM). Endoscopic findings revealed severe inflammation in the TM of C group; no other group showed damage in the TM. No significant difference in ABR threshold was found in the PBM-treated groups (excluding the group with TM damage). Confocal microscopy showed no histological difference between the AL and AN, or BL and BN groups. However, light microscopy showed more prominent edema, inflammation, and vascular congestion in the TM of BL ears. This study found a dose-response relationship between laser power parameters and TM changes. These results will be useful for defining future allowance criteria for trans-tympanic laser therapies.</P>

Magnetic resonance tracking of multifunctional nanoparticle-labeled mouse mesenchymal stem cells in a mouse model of myocardial infarction

Lee, K.,Park, C.,Moon, H.Y.,Ahn, E.,Park, H.E.,Ihm, S.H.,Seung, K.B.,Yoon, T.J.,Chang, K.,Lee, C.,Cheong, C.,Hong, K.S. Elsevier 2009 Current Applied Physics Vol.9 No.1

Magnetic ferrite nanoparticles (MNPs) are nano-sized magnets that distort the local magnetic field and alter the T<SUB>2</SUB> and T<SUB>2</SUB><SUP>*</SUP> of the water protons in the surrounding water molecules. This property renders MNPs a favorable negative MR contrast agent for biomedical applications. Silica coating and polyethylene glycolation confers additional stability and biocompatibility to the MNPs. Organic dyes incorporated into the silica shell enable the detection of MNP fluorescence by confocal laser scanning microscopy (CLSM). Mouse mesenchymal stem cells (mMSCs) in adult bone marrow can differentiate into cardiomyocytes. The mMSCs recruited in the region of myocardial infarction can express muscle-specific markers and increase the regional wall motion. Using MRI, we tracked the fate of MNP-labeled mMSCs injected into the infarcted myocardium. The mMSCs were effectively labeled with polyethylene-glycolated MNPs, as confirmed by CLSM. The MNP-labeled mMSCs were injected around and into the infarcted myocardium of C57/BL6 mice. Using MR, we successfully tracked the MNP-labeled mMSCs in the hearts of mice at 7d after inducing myocardial infarction. The localization of MNPs in the myocardium was validated by the in vivo and ex vivo MR images.

방사성동위원소옥소(131I)에 의한 갑상선질환의 임상적연구

정경태,이문호,이범홍,김목현,장고창,김명재,이장규 대한핵의학회 1967 핵의학 분자영상 Vol.1 No.1

$quot;서울대학교 의과대학 부속병원 방사성동위원소진료실에서 1960년 5월부터 1966년 6월까지 진료한 1,716명의 각종 갑상선 질환 환자에 대하여 131I에 의한 각종 갑상선기능검사를 실시하는 동시에 갑상선 기능항진증에 대한 131I의 치료성적을 종합검토하여 아래와 같은 결론을 얻었다. 1) 1,716예의 갑상선질환중 중독성미만성선종이 596명 (34.7%)으로 가장 많았으며 비중독성결절성선종이 412명 (24.0%), 정상기능이 278명 (16.2%), 비중독성미만성선종이 236명 (13.8%), 기능저하가 89명 (5.2%), 중독성결절성선종이 53명 (3.1%), 갑상선염이 32명 (1.9%), dyshormonogenesis가 20명 (1.2%)이었다. 2) 갑상선질환의 성별 발생빈도는 남자 218명 (12.7%), 여자 1,498명 (87.3%)로 그 비는 1:6.9이었다. 3) 연령별 발생빈도는 20∼40대가 1,365명으로 가장 많았으며 이는 전예의 79.6%이었다. 4) 각종 갑상선기능검사중 131I 갑상선섭취율, 131I 혈청내방사능, T3 시험, PB131I 전화율, BMR 등의 진단적가치를 논하고 각 검사의 정상범위에 대하여 고찰하였다. 5) 갑상선 기능항진증예 545명에 대한 131I의 완치율은 초회에 68.3%, 2회에 92.3%이었으며 1회 투여량은 6mC가 가장 많았다. 6) 131I 투여$quot; Over the past 6 years, from May 1960 to June 1966, 1,716 patients with various diseases of thyroid were examined and thyroid function tests with 131I were done. Among them, 545 patients with hyperthyroidism were treated with (131)^I. A summary of the clinical data of the (131)^I-thyroid function tests and the therapeutic results of (131)^I were presented and discussed. 1) The patients examined consisted of;596 cases (34.7%) with toxic diffuse goiter, 412 cases (24.0%) with non-toxic nodular goiter, 278 cases (16.2%) with euthyroidism, 236 cases (13.8%) with non-toxic diffuse goiter, 89 cases (5.2%) with hypothyroidism, 53 cases (3.1%) with toxic nodular goiter, 32 cases (1.9%) with thyroiditis and 20 cases (1.2%) with dyshormonogenesis. 2) There were 218 (12.7%) male patients and 1,498 (87.3%) female patients, showing a ratio of 1:6.9, female predominantly. 3) The majority of patients (79.6%) were in the 3rd through 5th decades of their lives showing the peak in the 4th decades (35.9%). 4) The diagnostic values and normal ranges of (131)^I uptake test, 48 hour serum activity, T3 red blood cell uptake and PB131I conversion ratio were discussed. 5) An attention was given to dyshormonogenesis, a qualitative hypothyroidism, due to its characteristic findings of clinical and (131)^I thyroid function tests, and its pathogenesis was briefly reviewed. 6) Among 545 patients with hyperthyroidism treated with (131)^I, 68.3% was cured after single therapeutic dose and another 24.0% was cured after second dose. 7) The complications of (131)^I therapy were discussed in some details and myxedema had developed in 3.9% of our cases. No thyroid cancer was found after (131)^I therapy.

중성자 조사 및 열처리에 따른 SA508 Cl.3강의 자기특성 변화

장기옥(K. O. Chang),김택수(T. S. Kim),심철무(C. M. Sim),지세환(S. H. Chi),김종오(C. O. Kim) 한국자기학회 1998 韓國磁氣學會誌 Vol.8 No.5

In relation to the application of magnetic method to the evaluation of irradiation damage (embrittlement) changes in the magnetic parameters(hysteresis loop and Barkhausen noise) and Vickers microhardness due to neutron irradiation and heat treatment were measured and compared. In the case of irradiation (2.3×10^(19) n/㎠, E≥1 Mev, 288 ℃) hysteresis loop measurements show that susceptibility decreases as coercivity increases. Saturation magnetization do not show any change. Barkhausen noise amplitude and Barkhausen noise energy have decreased while Vickers microhardness has increased. For isothermally heat treated condition of irradiated specimen at 470 ℃ and 540 ℃, Barkhausen noise energy has increased while Vickers microhardness has decreased. Results of BNE and Vickers microhardness are reversed to the results on irradiated condition. All these consistent changes in magnetic parameter and Vickers microhardness measurement, which are thought to be resulted from the interaction between irradiationinduced defects and dislocation, and magnetic domain, respectively, show a possibility that magnetic measurement may be used to the evaluation of material degradation and recovery due to neutron irradiation and heat treatment, respectively, if a relevent large database in prepared.

Holstein 보증종모우 및 후보종모우의 선천성 장애 유전좌위 검색에 관한 연구

이연근,장길원,남인식,장원경,탁태영,김경남,이광전 한국동물자원과학회 2002 한국축산학회지 Vol.44 No.3

본 연구는 국내 홀스타인 젖소 보증종모우 16두와 후보종모우 93두를 이용하여 선청성 장애 유전자의 검색을 통하여 불량 유전자의 존재 유무를 판별함과 동시에 가축의 선발 및 육종, 개량시 기초자료로 제공하고자 하는데 그 목적이 있으며, 본 연구의 결과를 요약하면 아래와 같다. 공시재료(홀스타인 젖소 보증종모우 16두, 후보 종모우 93두) 109두에 대하여 DUMPS(deficiency of uridine monophophate synthase)의 검색결과 모든 개체에서 DUMPS 유전자를 보유하는 개체는 없는 것으로 판명되었다. 또한 PCR-RFLP(AvaⅠ) 방법에 의해 조기 검색이 가능하게 되었다. 한편, BLAD(bovine leukocyte adhesion deficiency) 검색결과, 보증종모우 16두에서는 검출되지 않았으나, 후보우 93두중 5두에서 BLAD 잠재성 보유개체(carrier)로 판명되었고, 혈통확인을 통하여 BLAD 유전자의 전이 경로를 추정할 수 있었으며, PCR 증폭산물에 대한 제한효소 처리시 HaeⅢ 보다는 TaqⅠ 제한효소를 사용하였을 때 더 효율적으로 판명할 수 있는 것으로 나타났다. Citrullinemia 검색결과 보증종모우 16두 및 후보종모우 93두 모두에서 잠재성 보유개체는 없는 것으로 판명되었으나 citrullinemia에 대한 폭넓고 다양한 조사 및 분석이 이루어져야 할 것으로 사료된다. 본 연구의 결과로 미루어 볼 때 가축의 유전성 질환에 대한 다양하고 폭넓은 연구가 이루어 져야 할 것으로 사료되며, 가축의 선발과 육종, 개량에 있어서 지속적이며 혈통의 철저한 관리를 통한 개량의 방향을 설정하여야 할 것으로 판명되었다. This study was performed to discriminate defective loci by detection of congenital genetic disorder, to offer basic data for selection and improvement of Korean dairy cattle using frozen semen of Holstein bulls(16 proven and 93 candidate). The results obtained were as follows ; By the detection of DUMP(deficiency of uridine monophophate synthase) for 109 Holstein bulls(16 proven and 93 candidate), DUMP carrier was not found in whole animals. Also, it was possible to early detection of DUMP carrier by using PCR-RFLP(AvaⅠ). As the results of detection for BLAD(bovine leukocyte adhesion deficiency), BLAD carrier was not found in 16 proven bulls. But 5 candidtae bulls are discriminated to BLAD carrier, and it could be predicted to transmitted pathway of inherited loci by pedigree identification. Also, when digesting PCR products using restriction enzyme, results from Taq Ⅰ restriction enzyme were more efficient than that of HaeⅢ. After detection test of citrullinaemia, it was concluded that proven and candidate bulls were not. However, wide range of research and citrullinaemia genotyping should be performed. As a result of this study, the wide and various research should be performed in genetic disease of animal. And in the selection and breeding of animal, the breeding scheme by completely and continuously management of pedigree should be established.

保健要員 敎育訓練評價에 關한 調査硏究 : 評價體系開發 Development of M. C. Q. Bank

김학기,박노예,박남영,장영섭,이용우,김기경,안상우,김태숙 국립보건연구원 1989 국립보건원보 Vol.26 No.