PHV年齡에서 본 體格 ·體力의 發育 ·發達 速度曲線에 관한 연구

朴哲浩,朴贊熙,朴俊東,朴相甲,辛尙根 東亞大學校附設스포츠科學硏究所 1992 스포츠科學硏究論文集 Vol.10 No.-

The purpose of this study was to examine the timing and sequence of growth and development velocity curves of some physique and physical fitness aligned on age at peak height velocity. The study design, the subjects, and the method used in cross-sectional investigation reported by Ministry of Physical Education and Youth of Korea(1989). According to the reported by Ministry of Physical Education and Youth, the subjects participated in goverment study were 7 through 50 over years of age who belonged to typical primary, junior and senior high school, college and adult, and about 550 males and 550 females in each age. Thus, the total sample size were 6,316 males and 6,316 females. Grand total was 12,632. For physique measured, 2 body linearity items ; body height and sitting height, 5 body bulk items ; body weight, chest girth and 3 site skinfold thickness items were selected. For physical fitness measured, 8 items such as grip strength, sit-ups, 10m shuttle run, standing long jump, 50m dash, long distance run, eyeclosed foot balance and trunk flexion were selected. Measurements were actually worked out in April through July, 1989. The mean and the standard deviation were computed for each itesm, each age, and each sex, respectively. The growth and development velocity magnitudes of some physique and physical fitness in this study were calculated by personal computer. The conclusion obtained as follows. 1. Ages at PHV occurred earlier about 3years than males on the average. 2. Maximal annual increments (PV) in body weight, chest girth and sitting height appeared to coincide with PHV in males, but, to about 1 and 2 years after PHV in females. 3. Two occurrence of peak velocity gained in the chest girth for males and 3 site skinfold for females. In contrast, peak velocity of triceps skinfold was not appeared in males. 4. Peak velocities of grip strength and trunk flexion occurred about 1 to 2 years after PHV in both sexes. Peak velocities of 50m dash and long distance run occurred about 1 to 2 years after PHV in males. 5. Peak velocities of sit-ups, standing long jump and eyeclosed foot balance occurred about 1 to 2 years before PHV in both sexes, respectively. 6. Peak velocity of 10m shuttle run was not occurred in both sexes, peak velocity of 50m dash was not occurred in females. 7. Generally, peak velocities of physique and physical fitness occurred earlier about 1 to 3 years in females than in males.

당뇨병환자에서 뇨증 Fibronectin농도의 증가에 관한 연구

한승범,조준승,손건영,서성문,박근용,조성래,박규영,박정모,이인규,여준기 啓明大學校 醫科大學 1994 계명의대학술지 Vol.13 No.4

Plasma fibronectin is an α₂-glyoprotein, which is produced by vascular endothelial cells. Raised level of plasma fibronectin has been observed in diabetic patients particularly in the presence of microvascular complications. However, no available data exist about urine level of this glycoprotein in diabetic patients. We measured urine fibronectin level by ELISA methods in 54 diabetic patients who have microvascular comlications or not. The following results were obtained. 1) Urine fibronectin level(㎍/g creatinine) in diabetic group(1740.0±678.0) is increased compaired with those in normal control group(471.0±59.0). but this results were not significantly different among two groups(P>0.05). 2) Urine fibronectin level(㎍/g creatinine) was significantly increased in patients with nephropathy (6188.0±3144.0) compared with those in normal control group(471.0±59.0) and patients without nephropathy(645.0±251.0)(P<0.001). 3) There were a significant correlation between BUN, creatinine, creatinine clearance, 24hr urine total protein and urine fibronectin level in diabetic patients. Our data suggest that urine fibronectin excretion level might be used as a sensitive guide for diabectic nephropathy.

섬유판에서 음향방출원의 위치표정

박익근,김용권,윤종학,노승남,서성원 한국공작기계학회 2003 한국공작기계학회 추계학술대회논문집 Vol.2003 No.-

음향방출 신호를 이용하여 목재 섬유판(fiberboards)의 위치표정의 유용성 유무를 실험적으로 검증하였다. 위치표정의 정확도를 향상하기 위해 신호처리 방법중의 하나인 웨이블릿 변환 디노이징 기법을 활용하여 저주파수인 대칭모드(굽힘파)를 활용하고, 고주파수인 비대칭 모드(팽창파)룰 제거하여 신호를 재구성함으로써 섬유판의 위치표정시 문턱값 통과방법을 사용할 때 발생하는 도달시간차를 최소화 할 수 있음을 확인하였다. 디노이징 기법을 활용한 섬유판의 위치 표정과 굽힘강도에 대한 사상총수를 기초로 하여 목재 구조물 및 문화재의 건전성을 평가 할 수 있을 것으로 기대된다.

식품내 미생물 동정을 위한 DGGE와 TGGE의 응용

박성희,김근성 중앙대학교 유전공학연구소 2003 遺傳工學硏究論集 Vol.16 No.1

분자생물학적 기법중 미생물군의 분석에 유용하게 이용되고 있는 DGGE(denaturing gradient gel electrophoresis)와 TGGE(tempertature gradient gel electrophoresis)의 기술에 대한 원리와 식품의 발효과정 중 변화되는 미생물 동정 사례를 고찰하였다. 이 기법들은 PCR 산물을 염기서열 분석 이전에 미생물군의 유전자 fingerprinting을 통하여 분석함으로서 배양에 의존하는 기존의 미생물학적 방법들 보다 빠르면서도 높은 감도를 통하여 효율적으로 분석할 수 있다. 그러므로 DGGE/TGGE 기술은 식품내에 존재하는 분리 될 수 있는 다양한 세균 균주의 동정에 이용될 수 있는 최근에 개발된 분자생물학적 기법이다. We describe the theoretical and practical aspects of DGGE(denaturing gradient gel electrophoresis) and TGGE(tempertature gradient gel electrophoresis) and their applications to the analysis of food microbial communities. DGGE or TGGE is routinely used to compare levels of diversity of microbial communities and to monitor population dynamics. Genetic fingerprinting techniques including DGGE or TGGE of PCR-amplified DNA fragments are more sensitive, rapid and effective than phenotypic techniques including traditional laboratory cultivation. Therefore, PCR-DGGE or TGGE techniques will be more frequently chosen as a new tool to differentiate diverse foodborne bacterial strains from each other.

Mitomycin-C 적용시간에 따른 누낭비강연결술의 수술결과

박근성,임진호,민병무,최시환,김창식,김용백 충남대학교 의학연구소 2001 충남의대잡지 Vol.28 No.2

To determine the usefulness of application of Mitomycin-C (MMC) and effectiveness of different concentration of MMC in external DCR. A total of 100 eyes of 87 patients diagnosed with primary acquired nasolacrimal duct obstruction were assigned randomly to either a MMC group or control group. The surgical procedures in both groups were same. In MMC group, a piece of neurosurgical cottonoid soaked with 0.4 mg/ml MMC was applied to the osteotomy site and then was removed after 5 and 10 minutes differently. Nasoendoscopic examination was performed at 1 month, 3 months, and 6 months after surgery for all patients. The causes of epiphora as trauma (20 cases), failed DCR (1 case), sinus surgery (2 cases), unknown (77 cases). The overall anatomical success rate of the procedure was 88% and functional success rate was 79%. Obstruction site was related to anatomical surgical results. Anatomical surgical outcome at lower lacrimal sac level group of patients showed a statistically significant success rate, but functional surgical outcome showed no significant difference between the two groups. The anatomical success rate was 87.7% and the functional success rate was 84.2% in MMC group. The anatomical success rate was 88.3% and the functional success rate was 74.4% in control group. Application of MMC and it's application time were not related to surgical results.

서울대학교 교육연구동 LCA분석 사례 연구

박태근,범성우 목원대학교 건축도시연구센터 2003 建築·都市環境硏究 Vol.11 No.-

It has taken a growing interest about environmental problems such as global warming and water pollution for the last century. Because of intensified environmental problems, it would be going on the research about environmental preservation and harmful factor reduction. Also, it makes ISO to show the quantitative data about LCA analysis. The research of LCA method in the domestic construction industry has advanced stealing from a national point of view. In this study, it would be possible to confirm the feasibility of a plan by LCA analysis. Moreover, the result of life cycle cost which deliberate the influence cost of environment in the steps of material production, construction, maintenance, and disposal has made to be 74,819,560,776 won in a plan and 78,979,469,602won in alternative. That is, it would analysis for a plan to reduce 4,159,908,826 won for alternative.

일부 부인과 양성 질환자의 지방조직 및 혈청의 PCBs와 DDE 농도

박성균,이강숙,노영만,구정완,민선영,한진구,고원경,김미란,정재근,이종승,김진홍 大韓産業醫學會 2000 대한직업환경의학회지 Vol.12 No.1

목적 : 본 연구는 지방조직과 혈청의 PCBs와 DDE 농도를 측정하고, 이에 영향을 미치는 것으로 알려진 요인들과의 관련성을 평가하고자 하였다. 방법 : 유방암, 자궁내막증 등 유기염소계 화합물의 영향이 있는 것으로 알려진 호르몬 관련 질병을 제외한 부인과 환자 52명을 대상으로 지방조직과 혈청을 분석하였으며, 설문조사를 통하여 연령, 교육수준, 직업, 비만도, 흡연과 음주, 출산력, 수유력등을 조사하였다. 지방조직과 혈청의 PCBs와 DDE 농도는 가스크로마토그래피를 사용하여 측정하였다. 결과 : 지방조직의 경우, 13개 PCBs congeners 농도의 합은 중앙값이 48.29 ng/g, 기하평균값이 56.78 ng/g이었고, DDE 농도는 중앙값이 142.89ng/g, 기하평균값이 117.06 ng/g이었으며, 혈청의 경우는 PCBs congeners 농도의 합은 중앙값이 4.67 ㎍/L, 기하평균값이 4.85 ㎍/L이었고, DDE 농도는 중앙값이 1.75 ㎍/L, 기하평균값이 2.09 ㎍/L로 나타났다. 지방조직과 혈청의 DDE 농도 사이는 높은 상관성을 보였으나(r²=0.310, p=0,0002), PCBs는 상관성이 약한 것으로 나타났다(r²=0.029, p=0.2582). 영향요인을 범주화한 후 로그변환 시킨 지방조직과 혈청의 PCBs, DDE 평균의 차이를 분석한 결과, 지방조직의 DDE만이 출산자녀수(p=0.015), 초산연령 (p=0.014), 비만지수(p=0.035)와 연관성이 발견되었다 다중회귀분석의 결과 지방조직의 DDE는 출산자녀수가 적을수록, 초산연령이 늦을수록 증가하는 경향을 보였다. 결론 : 출산자녀수와 초산연령, 비만도가 지방조직의 DDE와 관련성을 보였으며, 또한 유기염소계 화합물의 장기간의 노출에 의한 영향을 평가하는데 있어서 혈청보다 지방조직이 더 유용한 생물지표임을 알 수 있었다. Objectives : This study was purposed to determine the levels of PCBs and DDE in adipose tissue and serum and to evaluate the relations with factors affecting these levels. Methods : We analyzed adipose tissues and sera from 52 gynecologic benign disease patients aged 27-78 years, except hormonal diseases such as breast cancer and endometriosis. We also surveyed age, education, occupation, body mass index (BMI), smoking, drinking, number of children, and duration of breastfeeding by questionnaires. Tissue and serum levels of PCBs and DDE were measured using gas chromatography. Results : The median and geometric mean levels of PCBs were 48.29 ng/g, 56.78 ng/g for adipose tissue and 4.67 ㎍/L, 4.85 ㎍/L for serum, and those of DDE were 142.89 ng/g, 117.06 ng/g for adipose tissue and 1.75 ㎍/L, 2.09 ㎍/L for serum, respectively. Adipose tissue and serum levels for DDE showed high correlation (r²=0.310, p=0.0002), but those of PCBs didn't (r²=0.029, p=0.2582). In analyses of the differences of the means of log transformed adipose tissue and serum PCBs and DDE levels for groups of potential covariates, only adipose tissue DDE levels were significantly associated with number of children (p=0.015), age at first birth (p=0.074) and BMI (p=0.035). In multiple regression analysis, adipose tissue DDE levels were significantly increased with decreasing number of children and increasing age at first birth. Conclusions : This study suggested that parity and adiposity were associated with levels of DDE in adipose tissue, and adipose tissue is a better biomarker than serum for evaluating the long-term exposure of organochlorines.

마우스에서 오존수의 급여가 쥐와포자충 감염에 미치는 영향

박배근,김덕환,류시윤,김현수,조성환,전무형 충남대학교 수의과대학 동물의과학연구소 2000 動物醫科學硏究誌 Vol.8 No.-

Ozone is very effective in acute and chronic viral disease as a virucidal agent in reversing positive antibody tests and in improving the general health of the animals. The effects of ozonized water supply against Cryptosporidium muris was studied in 5-weeks-old mice. After oral inoculation of mice with 1×10^6 oocysts, ozonized water(0.5ppm) and tap water were supplied to experimental and control group, respectively. The prepatent period of both group was 8 days postinoculation(PI). The patent period of experimental group was longer(62days) than that of experimental group(57days). The number of oocysts in the feces were maxium on days 28 PI, indicating 3.54×10^6 oocysts/experimental mouse and 5.56×10^6 oocysts/ control mouse. The number of discharge oocysts during 12-33 PI was more in control group than that of experimental group. In the view of gastric gland section on days 28 PI, the number of endogenous development of C muris was smaller in experimental group than in control group. This results indicates that the autoinfected sporozoite were damaged by ozone.

완전뇌허혈후 재관류시에 국소뇌혈류, 체성감각유발전위 및 신경학적 회복에 대한 Mannitol과 Thiopental의 효과

박춘근,이상원,박영섭,최승진,허필우,정동섭,강준기,최창락 대한신경외과학회 1996 Journal of Korean neurosurgical society Vol.25 No.2

The cardiopulmonary bypass or cerebral circulation arrest is often used in the treatment of complex aneurysm or of arteriovenous malformation to decrease the risk of intraoperative aneurysm rupture. Although experimental studies have suggested that some drugs may protect the brain from ischemic injury, there are limitations in maintaining cerebral perfusion arrest without incurring neurologic deficits due to the initiation of detrimental processes including excitotoxic neuronal injury, activation of phospholipases, influx of calcium, and generation of damaging free radicals. The purpose of this study is to determine wheter mannitol or thiopental has any favorable effects on the recovery of neurologic deficits and on the regional cerebral blood flow(rCBF), somatosensory evoked potential(SEP) and electroencephalogram(EEG) in cats which underwent 15 minutes-complete global ishcemia-reperfusion. The complete global ischemia was produced in 38 cats by temporary intrathoracic occlusion of the innominate artery and the subclavian artery following ligation of bilateral mammary arteries and simultaneous induction of hypotension. The cats were allocated randomly to one of 4 treatment groups : (1) control group, 8 cats received equal volume of saline solution : (2) thiopental group, 10 cats received 45㎎/㎏ thiopental intravenously, (3) mannitol group, 10 cats received 2g/㎏ mannitol intravenously, (4) combined mannitol and thiopental group, 10 cats received equal dose of mannitol and thiopental intravenously. The drugs were administrated in a equally divided dosage before and after the ischemic episode. The results were as follos : 1) Eight animals which received saline showed the severe postischemic hypoperfusion and poor recovery of SEP and EEG, and 6 of them died within 6 hours after the ischemia. 2) Ten thiopental-treated animals also showed the severe postischemic hypoperfusion and poor recovery of SEP and EEG, and 6 of them died within 6 hours the ischemia. 3) Both mannitol-and combined treated groups showed early recovery of EEG, good recovery of SEP and EEG without the severe postischemic hypoperfusion, and 7 of 10 mannitol-treated animals and 8 of 10 combined treated animals were significantly recovered in all parameters. There were not significant differences in all parameters between the mannitol-and combined treated groups. 4) Thirty-four of 38 animals involved in this 15 minutes-ischemia resulted in the severe neurologic deficits inspite of treatment with mannitol, thiopental or both of them. These results suggest that, in cats, mannitol treatment is effective but not thiopental in preventing severe neurologic injury following complete global ischemia and the duration of complete ischemia should be far less than 15 minutes.

작업자의 작업쾌적성 향상을 위한 개선 활동의 실태에 관한 연구

박근상,엄기수,최성주 건국대학교 1997 學術誌 Vol.41 No.2

The purpose of this study is to suggest some definite ideas of increasing worker's work comfortability in industry. Namely, questionnaire survey including questions to inquire of the effective activities engineers and the company administrators adopted in relating to work comfortability was conducted. As for the number of the companies investigated was to totally five hundreds randomly selected among the whole and the various different type of industries. From the results, it can be cleared that workers are apt to think of their own personal and effluenced living life belong the most valuable and important in recent years due to the rapid development of economic conditions. And, furthermore, working area for workers is not thought to be limited only to their own workplace but should be covered the whole area even at home. The conclusion from this study shows that the appropriate countermeasures to increase comfortability of working conditions and environment should be equally important fur industrial workers together with improving work efficiency from the view point of management.