단일병원에서 관찰한 최근 10년간의 소아 우발사고에 관한 연구 : 이물흡인을 중심으로

김철민,송준영,김자형,김기수,홍수종 대한소아과학회 2002 小兒科 Vol.45 No.9

하루 콩단백질 25g 섭취를 위한 메뉴작성 및 영양성분 분석

한재숙,김정애,서봉순,이연정,서향순,조연숙,한경필,이신정,오옥희,우경자,조은자,구성자,김수진,李承彦,南出隆久 동아시아식생활학회 2002 동아시아식생활학회지 Vol.12 No.2

The purpose of this study was to develop menus for daily intake of 25g soybean protein and to analyse nutrients of these foods. Analytical values were compared to the theoretical one using the food composition table and recommended dietary allowances for Koreans (7th revision). The results are as follows. 1. Soybean curd residue stew, Soybean curd, Kimchi saute, and hard boiled soybean and lotus root were selected for the menu for January, of which the content of soy bean protein(SBP) was 33.1g, soybean stew, soybean curd and soybean sprout saute, and Italian deep fried soybean curd were for February, of which the content of SBP was 35.0g. The content of SBP in soybean paste soup with soybean curd, fried soybean curd and fried soybean curd roll, the menu for March, was 24.9g. That of April were soybean curd gratin with soymilk, soybean curd and ham with garlic dressing and the content of SBP was 26.3g. That of May were soybean porridge, soybean flour cake with honey (Dasik), soybean sprout soup and the content of SBP was 26.7g. That of June were soymilk, pan-fried soybean curd, steamed soybean curd with chicken and the content of SBP was 28.4g. That of July were noodle with soymilk, mapatofu, soybean curd salad and the content of SBP was 24.7g. That of August were soybean sprout with mustard dressing, Tossed green pepper with raw soybean flour, Tofu and Kimchi stew, soybean curd steak and the content of SBP was 26.2g. That of September were Chinese cabbage soup with raw soybean flour, sweet and sour tofu and the content of SBP was 23.2g. That of Oct. were Fermented soybean stew, soybean pan cake and the content of SBP was 24.3g. That of November were not-pressed soybean curd casserole, pan-fried mashed soybean curd with egg, stir frying deep-fried soybean curd with vegetables and the content of SBP was 22.4g. That of December were soybean curd and mushroom casserole, fried soybean curd and vegetables, hard boiled soybean curd and the content of SBP was 28.9g. 2. The ratio of the analytical value over theoretical value (A/B%) of one serving in kcal, carbohydrate, protein, fat, ash and dietary fiber were 57.7~107.7%, 42.9~131.9%, 79.2~118.3%, 54.5~100%, 40.7~80.8% and 42.1~113.2%, respectively. 3. The ratio of A/B% of one serving in Ca, K, Na, P and Fe were 44.1~93.6%, 59.0~153.1%, 53.1~117.7% 64.6%~138.8 and 33.8~77.3%, respectively. That in Fe was the lowest among minerals. 4. The ratio of analytical value over Korean R.D.A(A/C%) in Ca was relatively higher (22.0~85.9%) than that in kcal(18~63%). 5. The ratio of A/C% in Fe was 25.1~64.3% and lower than that in Ca and protein in general.

Urapidil, Labetalol의 투여가 기관내 삽관시 심혈관계에 미치는 영향

신용섭,윤석화,손수창,이원형,이정은,황원재,김만수,김영주,김혜자,최세진 충남대학교 의과대학 지역사회의학연구소 1994 충남의대잡지 Vol.21 No.2

We have examined the comparative efficacy of small doses of intravenous urapidil and labetalol in blunting hemodynamic response to endotracheal intubation and surgical incision in 30 patients without cardiovascular diseases. After intravenous urapidil 0.2 mg/kg or labetalol 0.2 mg/kg anesthesia was induced with thiopental 5mg/kg. Endotracheal intubation was facilitated by vecuronium 0.15 mg/kg with priming principle and anesthesia was maintained with enflurane and nitrous oxide in oxygen. Systolic, diastolic and mean arterial pressure and heart rate were measured before administration of the drugs, 5 minute after administration, just prior to endotracheal intubation and 1, 3, 5, 10 minute after intubatin. Also the peak blood pressures and heart rate within 10 minutes after surgical incision were measured. Endotracheal intubation and surgical stimulation were associated with significant increases in blood pressures and heart rate in both urapidil and labetalol group. Comparison of the changes in systolic, diastolic, and mean artrial pressures and heart rate between urapidil and labetalol group showed no significant difference except peak systolic pressure after surgical incision. It is concluded that the pressor response to endotracheal intubation and surgical stimulation are not influenced significantly by urapidil 0.2 mg/kg or labetalol 0.2 mg/kg. However, urapidil and labetalol preloading may be similarly effective in the blunting of the increases in blood pressures with larger doses of the durgs during anesthetic induction.

방사선 조사에 의한 흰주 난포의 퇴축과 난포세포의 방사선 감수성

김수일,한승로,조근자,허대영,이영호,조문준,김무강,김원식 충남대학교 의과대학 의학연구소 2002 충남의대잡지 Vol.29 No.1

The aim of this study were to investigate radiation-induced atresia and radiation susceptibility in the rat ovary morphologically. Female rats (Sprague Dawley strain) of 4 weeks old were irradiated with dose of 4 Gy and 8 Gy, and sacrificed at hour 6, 12, and 24 after radiation. The H & E stain, the TUNEL method (ApopTag kit) and transmission electron microscopy (TEM) were used. In light microscopic observation, the number of atresia of ovarian follicles were increased significantly at 6h after irradiation (p<0.01). There was no significant difference between 4 Gy and 8 Gy irradiated groups. In TEM observation, granulosa cells in radio-sensitive follicles were characterized by several structural features including condensation of nuclear chromatin granules, nuclear fragmentation and apoptotic body formation. An apoptotic cell is observed to have been phagocytosed by a normal granulosa cell. Granulosa cells in radio-resistant follicles were characterized by several structural features including nuclear indentation, partial condensation of chromatin granules, mitochondrial swelling, dilatation of RER cisterns, accumulation of dense irregular masses, accumulation of lipid droplets, and increased lysosomal bodies. Number of gap junctions between granulosa cells were decreased, and intercellular space were widen than that of control animals. These findings were prominent at 6h after irradiation and were diminished at 12h and 24h after irradiation. With these results, it was concluded that radiation-induced follicular cell apoptosis and ovarian follicular atresia in rat ovary increased considerably at 6h after irradiation. Further studies are needed to reveal the more extensive differences between radiosensitive and radioresistant follicular granulosa cells.

맥도날드의 진출을 통해 본 세계화와 지구지역화

김수자,송태현 이화여자대학교 이화인문과학원 2010 탈경계 인문학 Vol.3 No.3

For some years, there have been widespread and on-going discussions over the issue of globalization from various perspectives. Some take a positive view of the issue, saying that globalization, in the end, benefits all of us; others take a defensive stance against globalization, defining it as imperialist invasion. The same goes for the cultural globalization issue. Some argue that unless we make efforts to preserve our local culture, our cultures will be homogenized into one dominant global culture, and our cultural objects will become mere commodities in the global market with the trend of cultural imperialism. Others welcome globalization as benefiting cultural diversity, greatly esteeming the willingness of local cultures to embrace the larger global culture and assimilate into it. With our world globalizing, we are witnessing the phenomena of cultural homogenization as well as cultural heterogenization and cultural pluralism, all at the same time. In this context, the concept of glocality becomes very significant because glocalization, a combination of the terms "global" and "local," can serve as an alternative to globalization. Instead of local cultures becoming objects assimilated into global culture, glocalization may enable local cultures to better understand different cultures of the world. McDonald’s, a leading global brand, has become a symbol of globalization in cultural and economic contexts. McDonald’s, at the same time, represents glocalization with its regionalization efforts accommodating local cultures as it expands into many international markets. Since 1997, McDonald’s in Korea has been adapting to local Korean culture, offering a regionalized version of its menu, such as the Bulgogi Burger and the Shrimp Burger, to satisfy the palate of the Korean people. This wouldn’t have been possible without a deep understanding of Korean culture as well as of the sentiments of Koreans. As a multinational corporation, McDonald’s clearly saw the importance of keeping up with the current trends of local culture, communicating effectively inter-culturally, and implementing cultural regionalization strategically. Yet, on a closer look, we see the phenomenon of McDonald’s glocalization efforts as only superficial. In other words, McDonald’s regionalization efforts were made only for the purpose of making maximum profits in the market, without genuine interest in going local. Therefore, in research on glocality, we need to explore how two important issues of the preservation of local culture and the integration into global culture can go hand in hand and how a new paradigm of glocalized culture can be created.

중학생의 학교급식에 대한 음식기호도 : 광주,전남지역을 중심으로

김경애,김수자,정난희,전은례 한국조리과학회 2003 한국식품조리과학회지 Vol.19 No.2

A survey on meal preferences from 693 middle school students was conducted with the objective to enhance the quality of the school food service in Gwangju and the Chollanamdo area. Data were collected by questionnaires and analysed with the SAS program. The most preferred rice was cooked rice; the most unusual meal preference was laver rice; and the most-liked bread was sweet red bean jam bun. The noodle of choice was Tchajangmyon, and the most-liked rice cake was seasoned bar rice cake. The highest ranked korean soups were boiled fish paste soup, kimchi stew, and short rib soup. The most preferred fried meal included fried beef with sweet and sour sauce, and favorite side-dishes were seasoning vinegar squid and kimchi. Yogurt and strawberry were the preferred desserts. Agender difference in preferred foods was seen. The males tended to favor rice with blackish bean sauce, dumpling soup, beef bean curd soup, beef soup, short rib soup, beef bone and tripe soup, hot shredded beef soup, chopped roast chicken, pork roast, roast meat, steamed pork short-ribs, fried pork, fried ham, sausage, milk, and yogurt. Males were partial to staple foods and side dishes. The, females favored laver rice, seasoned bar rice cake, bean sprouts soup, fried squid ring, seasoned cucumber, seasoned bean sprouts, fried kimchi, fruits salad, corm salad and citrus fruits. Females tended to choose lighter meals. Meal preference according the residential area showed that, students in Gwangju had more preferences than students in the Chollanamdo area. Classified according the grades. third graders had the greatest meal preference.

NAD^+유도체의 합성과 성질에 관한 연구

김수자,김광현,김진희 慶熙大學校 1990 論文集 Vol.19 No.-

N^1-position of adenine ring of NAD^+ was carboxymethylated using iodoacetic acid and after Dimroth rearrangement gave N^6-carboxymethyl-NAD^+. N^6-[(6=aminohexyl) carbamoylmethy1]NAD^+ was synthesized by condensation of N^6-carboxymethyl NAD^+ with 1,6-diaminohexane dihydrochloride in the presence of EDAC. All these analogs were active as coenzymes for YADH and LDH catalyzed reactions. Kinetic studies showed that the modification of exocyclic amino group of NAD^+ led the coenzyme binds to enzyme more favorably than unmodified coenzyme.

단일기관에서 경험한 미만성 거대 B 세포 림프종의 Rituximab 사용후 향상된 치료효과

김자경,김양수 고신대학교의과대학 2008 고신대학교 의과대학 학술지 Vol.23 No.4

Background : Diffuse large B cell lymphoma(DLBCL) is the most common type of non Hodgkin lymphoma and its prevalence is recently increasing . Rituximab combined chemotherapy is proved to be a standard treatment of DLBCL, and patients treated with Rituximab combined chemotherapy are known to have more longer survival than patients with chemotherapy alone. This study was performed retrospectively to compare the survival rates of Rituximab combined chemotherapy with those of chemotherapy only at the single institution. Patients and Methods : From Sep 2001 to Feb 2008, DLBCL patients were newly diagnosed at the department of hemato-oncology at the Kosin University Gospel Hospital and they were included in this study. The median age of all the 73 patients was 53 years old(range 23-81 years). All the patients were devided into the Rituximab-combined CHOP(cyclophosphamide, vincristine, adramycin, prednisone) group(n=35) and CHOP only(n=38). The chemotherapeutic drugs and cycles were the same in patients of both groups. We analyzed the results of complete response(CR) rate, relapse free survival(RFS), and overall survival(OS) between the two groups. We, also, compared the results of survival rate according to intenational prognostic index (IPI). Results : CR rate was higer in R-CHOP group than in CHOP group(97.1% vs 76.3%, p=0.01). Two years RFS rate was higher in R-CHOP group than in CHOP group(95.8% vs 65.5%, p=0.005). And 2 year OS rate was higher in R-CHOP group than in CHOP group(85.8% vs 65.8%, p=0.071). Conclusion : In patients with DLBCL, CR rate, and 2 year RFS and OS rates were significantly higher in R-CHOP group than in CHOP group. Long term follow-up are needed to confirm these results.

Glucocorticoid가 비장세포 임파구의 증식,Interleukin-2(IL-2) 생산 및 말초 혈액 임파구의 IL-2수용체 발현에 미치는 영향

김정목,조양자,이수영,박장환 漢陽大學校 環境科學硏究所 1992 環境科學論文集 Vol.13 No.-

Glucocorticoids are widely used as therapeutic agents in as variety of allergic and inflammatory diseases and in transplantation rejection. Although glucocorticoids are thought to influence on the immunologic reation, they are not fully known to influence on the immune cell function. In this report, we have studies effects of glucocorticoid. dexamethasone, on porliferation and production of interleukin-2(IL-2) in mouse splenic lymphocytes and on expression of IL-2 production, we isolated C57BL6 mice splenic cells and stimulated with Con-A(5㎍/ml). As the concentration of dexamethasone was increased, the proliferation and the IL-2 production of mouse splenic lymphocytes stimulated by Con-A (5㎍/ml) were decreased. And the expression of IL-2 receptors in human peripheral blood lymphocytes was also decreased in addition of dexamethasone. These findings suggest that proliferation, IL-2 production, and IL-2 receptor expression of immune cells are inhibited by glucocorticoid, dexamethasone.

개구부 보강철근의 배근방법이 고강도 철근콘크리트 깊은 보의 전단거동에 미치는 영향

김자영,김광두,양근혁,정헌수 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.2(구조계)

The purpose of this experimental study is to understand the effect of configuration of web opening reinforcement on the shear behavior of reinforced high-strength concrete deep beams with rectangular opening. The configuration including the vertical, the horizontal and the diagonal web opening reinforcements are considered as main variable. The test specimens shaped over-all depth of h 60cm, width of b 16cm and length of L 240cm were made of 8 simply supported high-strength concrete deep beams and the size of the web opening is fixed by 0.5a×0.3h. The test results show that diagonal web opening reinforcement comparing both vertical and horizontal reinforcements is the most efficient in restricting the diagonal crack width development and enhancing the shear capacity.