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충남대학교 학술림 산책로 훼손실태 및 관리방안에 관한 연구
이준우,김명준,최윤호,전용준,오도교,김민호,이소연,이경형 충남대학교 농업과학연구소 2004 농업과학연구 Vol.31 No.2
This study concentrates an the trail of the CNU(Chungnam National University) forest. The amount of use and the pattern of damage are considered, as well as the extent of environmental damage. Finally, some managerial strategies are proposed in connection with sustainable maintenance. The trail of the university forest is composed of three sections; one is the neighborhood park and the Institute of Information Technology/Communications, the second is the Institute of Information Technology/Communications and the Dormitory, and the third section is the Dormitory and the Foreign prof's Apt. The total length of the trail is 2.6km. The daily amount of use is 1,269 visitors per day. The amount of using increased three times the amount of that in 1998. This study shows the pattern of damage of the trail in the order of root-exposure, widening, rock-exposure, deepening and the divergence in the frequency of occurrence of all these factors. Environmental damage is also graded thus: grade 3 is 27.4m, grade 4 is 0.8m, grade 5 is 1.5m, and grade 6 is 0.2m. Accordingly, some managerial strategies were proposed in connection with the sustainable trail maintenance.
도립 진자 시스템의 안정화를 위한 퍼지 제어기의 실현에 관한 연구
최우진,이준탁,소명옥 동아대학교 공과대학부설 생산기술연구소 1996 生産技術硏究所硏究論文集 Vol.1 No.-
In this paper, a hierarchical fuzzy controller for stabilization of the inverted pendulum system is proposed. The facility of this hierarchical fuzzy controller which has a swing-up control mode and a stabilization one, moves a pendulum in an initial natural stable equilibrium point and a cart in an arbitrary position, to an unstable equilibrium point and to a center of rail. Specially, the virtual equilibrium point(Φ_VEq) which describes functionally considers the interactive dynamics between a position of cart and a angle of inverted pendulum is introduced. And comparing with the conventional optimal controller, the proposed hierarchical fuzzy inference structure made substainally the inverted pendulum system robust and stable.
사막화방지(沙漠化防止) 및 방사기술개발(防沙技術開發)에 관한 연구(硏究)(II) - 중국(中國)의 경관(景觀)-생태(生態) 방호림조성기술(防護林造成技術) 및 효과분석(效果分析) -
우보명,이경준,전기성,김경훈,최형태,이승현,이병권,김소연,이상호,전정일,Woo, Bo-Myeong,Lee, Kyung-Joon,Jeon, Gi-Seong,Kim, Kyung-Hoon,Choi, Hyung-Tae,Lee, Seung-Hyun,Lee, Byung-Kwon,Kim, So-Yeon,Lee, Sang-Ho,Jeon, Jeong-Ill 한국환경복원기술학회 2000 한국환경복원기술학회지 Vol.3 No.3
The shelterbelts are very important to conserve and protect the sandy land, vegetation coverage, farmland, livestock and human life in the desertified land. The shelterbelts are constructed by the several row-plantings of high-adaptable species in the desertified land. The shelterbelts have various kind of type, and there are shelterbelts for conservation of farmland in dry the region, the protective shelterbelts (windbreaks for blowing-sand, artificial sanddune fixation by revegetation, and construction of farmland shelterbelts to protect farmland and pasture from wind erosion, etc.) in the semi-dry steppe, shelterbelts around the villages and oasis for sanddune fixation, shelterbelts for protection of railroads, and so on. The shelterbelts consist of main she1terbelts and minor shelterbelts. The main shelterbelts were constructed by being perpendicular to main wind direction, and the minor shelterbelts were constructed by being perpendicular to the main shelterbelts. Generally, the width of shelterbelts is 8~20m, and the number of row-planting is 4~10. The grid sizes of shelterbelts networks are $400{\times}400m$, $300{\times}500m$, $100{\times}200m$, and so on, and there are ventilation type and closing type in the type of shelterbelt. The width, number of row-planting, grid size and type of shelterbelt are selected by the local characteristics. The effects of shelterbelts are mainly the climate improvement and mitigation, such as prevention of occurrence of strong wind, cold wind and blowing-sand. And, the other effects of shelterbelts are effect of reforestation, increase of agricultural productions, establishment of greenbelts and green forests, construction of landscape-eco shelterbelts, improvement of life environment of local villages, supply of fuel wood and agricultural wood, land amelioration, effect of revegetation and restoration of desertified land, and so on. The kinds of the tree species mainly used for the construction of shelterbelts have differences between regions, but main species are Populus euphratica, Populus simonii, Populus bolleana, Populus tomentosa, Salix flavida, Salix mongolica, Tamarix chinensis, Hedysarum scoparium, and so on.
Myeong, J.,Ko, J.,Hong, C.,Yang, D.,Lee, K.P.,Jeon, J.h.,So, I. Academic Press 2016 Biochemical and biophysical research communication Vol.474 No.3
Transient receptor potential canonical (TRPC) family contains a non-selective cation channel, and four TRPC subunits form a functional tetrameric channel. TRPC4/5 channels form not only the homotetrameric channel but also a heterotetrameric channel with TRPC1. We investigated the interaction domain required for TRPC¼ or TRPC1/5 heteromultimeric channels using FRET and the patch-clamp technique. TRPC1 only localized at the plasma membrane (PM) when it was coexpressed with TRPC4 or TRPC5. The TRPC¼ or TRPC1/5 heteromultimeric showed the typical outward rectifying I/V curve. When TRPC1 and TRPC4 form a heteromeric channel, the N-terminal coiled-coil domain (CCD) and C-terminal 725-745 region of TRPC1 interact with the N-terminal CCD and C-terminal 700-728 region of TRPC4. However, when TRPC1 and TRPC5 form a heteromeric channel, the N-terminal CCD and C-terminal 673-725 region of TRPC1 interact with the N-terminal CCD and C-terminal 707-735 region of TRPC5. In conclusion, the N-terminal CCD of TRPC channels is essential for the heteromultimeric structure of TRPC channels, whereas specific C-terminal regions are required for unique heteromerization between subgroups of TRPC channels.
Lee, Jae-Myeong,Lee, Joo Won,Jeong, Tae Seok,Bang, Eun Sook,Kim, So Hee American Society for Microbiology 2018 Antimicrobial Agents and Chemotherapy Vol.62 No.10
<P>Meropenem is an ultrabroad-spectrum antibiotic of the carbapenem family. In brain-dead organ donors, administration of standard meropenem dosages does not reach therapeutic levels. Our objectives were to determine the plasma concentration of meropenem after the administration of standard meropenem dose and to estimate an improved dosage regimen for these patients. One gram of meropenem was administered as a 1-h infusion every 8 h for 1 to 3 days, and blood samples were collected. The plasma concentration of meropenem was measured and subjected to pharmacokinetic analysis. Simcyp simulation was performed to predict the optimum plasma levels and dosage based on the patients' individual pharmacokinetic parameters. The maximum plasma concentration of meropenem was 3.29 mu g/ml, which was lower than four times the MIC of 8 mu g/ml. Although the mean creatinine clearance of patients was moderately low (67.5 ml/min), the apparent volume of distribution at steady state (V-ss) and time-averaged total body clearance (CL) of meropenem were markedly elevated (4.97 liters/kg and 2.06 liters/h/kg, respectively), owing to massive fluid loading to decrease the high sodium levels and to treat shock or dehydration. The simulation revealed that dose and infusion time of meropenem should be increased based on patients' V-ss and CL, and a loading dose is recommended to reach rapidly the target concentration. In conclusion, a standard meropenem regimen is insufficient to achieve optimal drug levels in brain-dead patients, and an increase in dose and extended or continuous infusion with intravenous bolus administration of a loading dose are recommended for these patients.</P>
So Joon Myeong,Park Ji Ho,Kim Jin Gyeong,Park Il Rae,Ha Eun Yeong,Chung Seung Min,Moon Jun Sung,Park Chul Hyun,Yun Woo-Sung,Kim Tae-Gon,Kim Woong,Yoon Ji Sung,Won Kyu Chang,Lee Hyoung Woo 대한의학회 2023 Journal of Korean medical science Vol.38 No.21
We assessed the risk factors for major amputation of diabetic foot ulcers (DFUs) in patients with diabetic kidney disease (DKD) stages 3b–5. For DFU assessment, in addition to DFU location and presence of infection, ischemia, and neuropathy, vascular calcification was assessed using the medial arterial calcification (MAC) score. Of 210 patients, 26 (12.4%) underwent major amputations. Only the location and extension of DFU, represented by Texas grade differed between the minor and major amputation groups. However, after adjusting for covariates, ulcer location of mid- or hindfoot (vs. forefoot, odds ratio [OR] = 3.27), Texas grades 2 or 3 (vs. grade 0, OR = 5.78), and severe MAC (vs. no MAC, OR = 4.46) was an independent risk factor for major amputation (all P < 0.05). The current use of antiplatelets was a possible protective factor for major amputations (OR = 0.37, P = 0.055). In conclusion, DFU with severe MAC is associated with major amputation in patients with DKD.
이금영,소준노,장선일,윤명자 한국유전학회 1987 Genes & Genomics Vol.9 No.2
A karyological analysis was carried out on different Korean species of the family Gobiidae (10 genera, 3 subfamies). The preparations were made according to the flame drying method, and the karyotypes were analyzed by conventional Giemsa staining. Diploid chromosome number ranged between 40 and 50 (Acantho-gobius hasta, 44; A. sp., 42; A, lactipes, 40; A. flavimanus, 44; Acentro-gobius pflaumi, 50; Rhinogobius brunneus, 44; Chasmichthys dolichognathus, 44; C. gulosus, 44; Chaenogobius annularis, 44; C. castaneus, 42; C. mororanus, 42; Mugilogobius abei, 46; Favonigobius gymnauchen, 48; Odontobutis platycephala, 44; Tridentiger obscures, 44; T, sp., 44), and arm number was in the range of 40-96. Some detected chromosomal characteristics permitted establishing some karyotypic relationships among the different species investigated.