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Enoxacin의 Dansyl 유도체에 의한 형광광도 분석법
이경준,염정록 중앙대학교 약학연구소 1990 약학 논총 Vol.4 No.-
A sensitive and specific method is described for the determination of a new secondary aromatic amine chemotherapeutic drug, Enoxacin. The highly fluorescent Dns-derivative of Enoxacin has been obtained by reacting ethanol solution of Enoxacin with Dns-Cl in acetone and sodium bicarbonate aqueous solution. The Dns-derivative is extracted with methylene chloride and its concentration is measured using a spectrofluorimeter in methanol solution(excitation wavelength : 415nm, emission wavelength : 535nm). The amount of Dns-Cl and 0.1M-NaHCO_3, reaction temperature, reaction time, stability of Dns-derivative and extraction solution were investigated to determine the quantitative potential of the method. Limit of detection is 0.1㎍ / ml with linear response up to 8㎍ / ml and 40㎍ / ml(as Enoxacin in methanol). The fluorescent labelled method is very stable and applicable to the determination of Enoxacin contained in pharmaceutical preparation.
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한국산과 미국산 모래밭버섯 균근균의 (菌根菌) 리기테다소나무 생장 촉진 효과 비교
이경준 한국산림과학회 1984 한국임학회 정기학술발표논문집 Vol.1984 No.-
Pinus rigida × P. taeda seedlings in a nursery was inoculated with basidiospores of Pisolithus tinctorius (Pt) either collected from Suweon, Korea or introduced from U.S.A. to compare the effectiveness of the spores from two different origins as mycorrhizal inocula. Nursery beds were fumigated with methyl bromide and lg of spores was used to inoculate 1㎡ of soil surface just before seed sowing. Seedlings inoculated with American Pt (#250 strain from Georgia, U.S.A.) were 15% taller than Korean Pt at the end of the first growing season. The seedlings from fumigation treatment only (no inoculation involved) was slightly taller (statistically unsignificant) than those with Korean Pt, but slightly smaller than those with American Pt. In a subsequent year experiment, the seedlings inoculated with American and Korean Pt after soil fumigation were 66% and 60% taller, respectively, than seedlings infected by natural fungi without soil fumigation, suggesting the dual effects of Pt and fumigation on the seedling growth. Therefore potential of Pt spores for an effective inoculum exists and selection of Pt strains which have adapted to specific local environments is needed to develop better sources of mycorrhizal inocula.
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이경준,이돈구,이원규,구창덕 ( Kyung Joon Lee,Don Koo Lee,Won Kyu Lee,Chang Duck Koo ) 한국산림과학회 1983 한국산림과학회지 Vol.59 No.1
Recently mycorrhizal research has been one of the most fast-growing research areas in modern plant science and microbiology. The application potential of mycorrhizal techniques to agriculture and forestry is enormous in view o1` the ubiquitous nature of mycorrhizae and known benefits of mycorrhizae to host plants. Unfortunately, very few scientists in Korea are currently involved in mycorrhizal research. When a team of American plant pathologists visited Korea in September 1982 to participate in the Korea-U.S.A. Joint Seminar on Forest Diseases and Insect Pests, they were surprised by the principal author`s statement that there was no single research project on mycorrhizae sponsored by Korean government or any scientific institutions. The author initiated a few years ago a research project on the ecology of tree mycorrhizae with a foreign financial support. Major areas of interest were survey of ectomycorrhizae in relation to soil fertility, taxonomic distribution of mycorrhizae among woody plants, identification of ectomycorrhizal fungi, and growth response of woody plants to artificial inoculation. In spite of the enormous application potential of mycorrhizae to agronomic plants, the subject of mycorrhizae has not been recognized by Korean agronomists, foresters or pathologists. The purpose of this review rather written in Korean is to introduce the techniques of mycorrhizal research to Korean scientists and to urge them to participate in challenging new scientific field which might bring us a remarkable increase in crop productivity and tree growth through manipulation of this unique symbiosis. In this review, following topics were discussed in the same order: introduction; brief history of mycorrhizal research; .morphology and classification of mycorthizae; distribution of mycorrhizae in plant kingdom and in soil profile; physiology of mycorrhizae (functions, mineral nutrition, mycorrhizal formation): interaction of mycorrhizae with soil-born plant pathogens mycorrhizae in nitrogen-fixing plants ; application of mycorrhizal techniques to nursery practices (isolation, culture, inoculation, and response); prospect in the future.
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이경준 한국데이터정보과학회 2023 한국데이터정보과학회지 Vol.34 No.5
In this paper, we consider the parameter for the exponentiated half logistic distribution (ExHfLg) when data are generalized type II hybrid censored (GenTy2HC) samples. The parameter for the ExHfLg is estimated by the Bayesian method. We consider conjugate priors (gamman and quasi prior) and corresponding posterior distributions are obtained. We also obtain the maximum likelihood estimator (MLE) of the parameter under the GenTy2HC samples. We compare the proposed estimators in the terms of the mean square error and bias. Finally, a real data set has been analysed for illustrative purpose.
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이경준 한국데이터정보과학회 2023 한국데이터정보과학회지 Vol.34 No.6
One limitation of the multiply hybrid censoring scheme (MulHyC) is that it cannot be applied when very few failures may occur before pre-fixed time. Therefore, generalized multiply hybrid censoring scheme (GenMulHyC) was introduced. In lifetime data analysis, it is also generally known that more than one cause or risk factor may be present at the same time. In this paper, therefore, we derive the esimators for uncertainty measure of the exponential distribution (ExpDist) based on GenMulHyC competing risks data. We compare the proposed estimators in the sense of the MSE and bias for various GenMulHyC. A real data set based on the GenMulHyC is also analyzed for illustrative purposes.
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