여가활동으로 스포츠 참여와 생활만족도

洪盛杓,權英桓 忠南大學校體育科學硏究所 1993 體育科學硏究誌 Vol.11 No.1

The purpose of this study was to analyze the degree of Life Satisfaction according to the sport participation as a Leisure activity and to find out the Casual relationship of Life Satisfaction in 390 of women who are taking part in Aerobics dance. Swimming and Bowling. The extent of leisure satisfaction and Devotion Experience Life Satisfaction were investigated also through questionnaire in Women Participating in the Leisure of Liberal, Audience or Spectator, and Rest type. The results were as fallows: 1. The degree of Leisure Satisfaction, Devotion Experience and Life Satisfaction in the Participants in sports as a Leisure active were significantly higher than those of Non-Participants in sports. 2. The Higher group in Leisure Satisfaction and Devotion Experience showed the high degree of Life Satisfaction also. 3. The were no significant differences among Leisure Satisfaction Devotion Experience and Life Satisfaction was by event of sports. The result showed that Participation in sports as a Leisure activity can elevate the degree of Life Satisfaction by enlarging the degree of Leisure Satisfaction land Devotion Experience.

항정신병약물 사용 중인 정신분열병 환자에서 올란자판으로의 교체 방법에 관한 연구(II) : Comparison of Safety 안전성 비교

안용민,권용실,권준수,민성호,박두병,양문정,소형석,송종호,신윤식,우행원,유범희,이홍석,정한용,한창환,김용식 大韓神經精神醫學會 2002 신경정신의학 Vol.41 No.5

연구목적: 이 다기관 공동임상연구는 사용 중인 항정신병약물을 ’직접 교체 방법’또는 ’시작-감량 교체 방법’중 한 가지 방법으로 올란자핀으로 교체한 후, 안정성 측면에서 두 교체 방법 간의 비교와 교체후의 변화를 관찰하기 위한 것이다. 방법: 국내 13개 병원의 입원 및 외래에 내원한 환자들 중 ICD-10 지단기준으로 정신분열병에 해당되며, 임상적으로 항정신병약물 교체가 필요한 환자를 대상으로 하였다. 두 가지 교체 방법 중 한 가지를 무작위로 피험자에 적용하였으며, ’직접 교체 방법’에 배정된 경우에는 사용중인 항정신병약물을 일시에 중단하고 10㎎의 올란자핀을 바로 투여하였고, ’시작-감량 교체 방법’에 배정된 경우는 10㎎의 올란자핀 투여하고 2주에 걸쳐서 기존 약물을 감량하여 중단하였다. 올란자핀 사용기간은 총 6주이며, 용량은 5∼20㎎ 범위로 제한하였다. 한정성 평가를 위해서 체중, 생명징후, 자발적인 이상반응 복, 실험실 검사 그리고 Simpson-Angus Scale(SAS), Barnes akathisia rating scale(BARS), Abnormal involuntary movement scale(AIMS). Liverpool University neuroleptic side effect rating scale(LUNSERS)등을 이용하였다. 결과: 총 103명의 정신분열병 환자를 대상으로 하였다. 사용한 올란자핀의 용량, 벤조디아제핀의 병용률, 탈락률과 탈락 사유, 자발적인 이상반응 보고, 생명징후, 실험실 검사 그리고 대부분의 부작용 척도 상에서 임상적으로 의미 있는 차이를 두 교체 방법간에 발견하지 못하였다. 다만 AIMS의 감소는 ’직접 교체 방법’군에서 보다 적었고, 항콜린제의 병용률은 ’시작-감량 교체 방법’군에서 보다 많았다. 기저 상태에서 전체 피험자의 SAS와 BARS 점수는 각각 3.5점과 1.8점이었으며 70% 이상의 피험자가 고프로락틴 혈증을 보였다. 올란자핀으로 교체한 후, SAS, BARS, AIMS 점수의 유의한 감소가 있었으며 고프로락틴 혈증을 보인 피험자 분율도 약 30%이하로 감소하였다. 그러나 교체 방법과 상관없이 올란자핀 교체 후 유의한 체중 증가가 있었다. 결론: 이 연구를 통해 교체 방법에 관계없이 비교적 안전하고 용이하게 올란자핀으로 교체 할 수 있음을 알 수 있었다. 그리고 기존 항정신병약물을 올란자핀으로 교체함으로써 일부 부작용들을 줄일 수 있음을 간접적으로 관찰할 수 있었다. 하지만 이 연구는 여러 제한점과 문제점을 지니고 있기 때문에 보다 체계적인 연구를 통해 검정이 필요하리라 생각된다. Objectives: This multicenter clinical trial involving 13 hospital sites compared the safely of switching to olanzapine between ’direct switching method’ and ’start-tapering switching method’. Method: This study included both inpatients and outpatients who fulfilled the criteria for schizophrenia as defined in the ICD-10, and were in need to be appropriate for switching antipsychotics. Subjects were randomly assigned to one of the two switching methods. For ’direct switching method’group, previous antipsychotics were abruptly discontinued and 10㎎ of olanzapine was administered, and previous antipsychotics was gradually tapered for 2 weeks. Olanzapine was used for 6 weeks and the dose was adjusted within the range of 5-20㎎. The safety of switching to olanzapine was measured with vital sings including body weight, adverse events reported spontaneously, laboratory tests, and various scales such as Simpson-Angus Scale(SAS), Barnes Akathisia Rating Scale(BARS). Abnormal Involuntary Movement Scale(AIMS), and Liverpool University Neuroleptic Side Effect Rating Scale(LUNSERS). Results: 103 patients were switched to olanzapine in this study. The comparison between two switching methods did not show any significant difference in the dosage of olanzapine used, the concomitant use of benzodiazepine, the rate and reasons of drop-out, the adverse events, vital signs, laboratory tests, and most scales for measuring side-effects. However, the decrease in AIMS scores was significantly lower in ’direct switching method’ group, and the concomitant use of anticholinergics was comparatively greater in ’start-tapering switching method’ group. At baseline, SAS and BARS scores were 3.5 and 1.8 points respectively, and more than 70% of the subjects showed hyperprolactinemia. After switching to olanzapine, SAS, BARS, and AIMS scores were significantly decreased and the proportion of the patients with hyperprolactinemia was also decreased to less than 30%. However significant weight gain after the treatment of olanzapine was observed regardless of switching method. Conclusion: This study may suggest that switching to olanzapine can be done with relatively high safety regardless of switching methods and olanzapine can significantly decrease some side-effects induced by other antipsychotics.

수술로 절제된 간내담관암의 임상적 고찰

홍성권(Seong Kweon Hong),김한준(Han Joon Kim),최동호(Dongho Choi),이경근(Kyeong Geun Lee),박훤겸(Hwon Kyum Park),백승삼(Seung Sam Paik),이광수(Kwang Soo Lee) 한국간담췌외과학회 2003 한국간담췌외과학회지 Vol.7 No.1

간내 담관 협착을 동반한 Type Ⅳ-a 담관낭

홍성권(Seong Kweon Hong) 대한외과학회 2010 Annals of Surgical Treatment and Research(ASRT) Vol.78 No.2

Choledochal cysts are rare congenital anomalies of the bile ducts. They consist of cystic dilatations of the extrahepatic biliary tree, intrahepatic radicles, or both. The standard treatment of choledochal cyst is complete excision of cyst and drainage procedure. I report a case of 48-year-old women who was diagnosed with type Ⅳ-A choledochal cyst with intrahepatic bile duct stricture and large stones in extrahepatic choledochal cyst. Sixteen years ago, she received a cholecystectomy and Reux-en Y cystojejunostomy due to choledochal cyst. Because of the intrahepatic bile duct stricture I performed a left hepatectomy, complete cyst excision and hepaticojejunostomy. I report this case with a review of the literature.

간질환 환자 혈청에서 ELISA를 이용한 angiogenin 측정의 평가

권기운,이숭환,이성희,김홍주,이창화,김병훈,백인규,박동일,박성수,이동후 대한간학회 1996 Clinical and Molecular Hepatology(대한간학회지) Vol.2 No.1

Backgroud:Liver fibrosis by the progression of the chronic processes of the liver diseases induces deforrned microcirculations of the hepatic lobules. And this eventually resolted in portal hypertension. On the other hands, angiogenic stimu4nt factors are physiologically activated in order to repair the tissue damage. Overexpression of angiogenic factors, however, can stimulate neovascularization as in a fonnation of the tumor that liberates uncontrolled overgrowing of the tumor cells. Methods: To elucidate the dynamic changes of the serum concentration of angiogenin in chronic liver diseases, this study is intended to employ an ELISA in 44 pathologically proven patients. Quantikiae_(TM) human angiogenin kit (R & D,systems Inc. Mmneapolis, MN) was used for this investigation. Results:Mean value and standard error of angiogenin concentration (ng/ml) of the sera was 238.92+ 50.95 in 5 cases of chronic persistent hepatitis, 184.47+ 12.75 in 6 cases of chronic active hepatitis, 131.36+ 10.99 in 19 cases of liver cirrhosis, and 211.03+ 19.08 in 14 cases of hepatocellular carcinoma, respectively. Serum angiogenin level in the liver cirrhosis was significantly lower than in chronic persistent hepatitis(p=0.00336), and than in chronic active hepatitis(p=0.018673). Angiogenin concentration in hepatocellular carcinomas was significantly higher than the level of the liver cirrhosis investigated(p=0.00569). Conclusions:These data support that persistent inflammatory insults in the chronic hepatitis were compensated by the elevation of angiogenin but complete fibrosis as in liver cirrhosis showed the depressed level. And emerging of the hepatocellular carcinoma is accompanied by the elevated stimuli of angiogenin for the neovascularization.

Silk Fibroin Membrane as Guided Bone Regeneration in Rat Calvarial Defects

Kweon, Hae-Yong,Kim, Seong-Gon,An, Jin-Hee,Shim, Hye-Won,Yang, Byoung-Eun,Kim, Jwa-Young,Jo, You-Young,Yeo, Joo-Hong,Lee, Kwang-Gill Korean Society of Sericultural Science 2010 International Journal of Industrial Entomology Vol.21 No.2

Silk fibroin membrane was prepared and examined to know the feasibility of SF membrane as guided bone regeneration. The morphology of silk membrane was flat and smooth surface. The conformation of silk fibroin was $\beta$-sheet structure. When the silk membrane was applied on the rat calvarial defect model, it showed significantly higher new bone formation than uncovered control in histomorphometric analysis. The silk membrane was covered by thin fibrotic tissue and there was not observed any inflammatory cells infiltration. In conclusion, silk fibroin membrane could be useful materials for guided bone regeneration.

Detection of Mycobacterium kansasii Using DNA-DNA Hybridization with rpoB Probe

Kweon, Tae-Dong,Bai, Sun-Joon,Choi, Chang-Shik,Hong, Seong-Karp The Korea Institute of Information and Commucation 2012 Journal of information and communication convergen Vol.10 No.2

A microtiter well plate DNA hybridization method using Mycobacterium kansasii-specific rpoB DNA probe (kanp) were evaluated for the detection of M. kansasii from culture isolates. Among the 201 isolates tested by this method, 27 strains show positive results for M. kansasii, but the other 174 isolates were negative results for M. kansasii. This result was consistent with partial rpoB sequence analysis of M. kansasii and the result of biochemical tests. The negative strains by this DNA-DNA hybridization method were identified as Mycobacterium tuberculosis (159 strains), Mycobacterium avim (5 strains), Mycobacterium intracellulare (8 strains), and Mycobacterium flavescens (2 strain) by rpoB DNA sequence analysis. Due to high sensitivity and specificity of this test result, we suggest that DNA-DNA hybridization method using rpoB DNA probes of M. kansasii could be used for the rapid and convenient detection of M. kansasii.

A New Six-rowed, Covered Barley Cultivar, "Gwangan" with High Yield

Seong Bum Baek,Soon Jong Kweon,Dong Soo Park,Jong Nae Hyun,Jong Min Ko,Duck Yong Suh,Young Koo Son,Choon Woo Lee,Hong Sik Kim,Jong Jin Hwang,Jung Hyun Nam,Si Ju Kim,Jae Seong Choi 한국육종학회 2007 한국육종학회지 Vol.39 No.1

‘Gwangan’ is a new six-rowed covered barley cultivar developed by the National Institute of Crop Science (NICS), R.D.A in 2004. This cultivar is developed from a cross between “Mirak” and ‘Milyang59’ in 1995. An F6 selection was made at Milyang in 2001 an

Unipolar resistive switching properties of amorphous Pr_0.7Ca_0.3MnO₃ films grown on a Pt/Ti/SiO₂/Si substrate

Seong, T.G.,Lee, B.S.,Choi, K.B.,Kweon, S.H.,Kim, B.Y.,Jung, K.,Moon, J.W.,Lee, K.J.,Hong, K.,Nahm, S. Elsevier 2014 Current Applied Physics Vol.14 No.4

Amorphous Pr<SUB>0.7</SUB>Ca<SUB>0.3</SUB>MnO<SUB>3</SUB> (APCMO) films were grown on a Pt/Ti/SiO<SUB>2</SUB>/Si (Pt-Si) substrate at temperatures below 500 <SUP>o</SUP>C and the Pt/APCMO/Pt-Si device showed unipolar resistive switching behavior. Conduction behavior of the low resistance state (LRS) of the Pt/APCMO/Pt-Si device followed Ohm's law, and the resistance in LRS was independent of the size of the device, indicating that the conduction behavior in LRS can be explained by the presence of the conductive filaments. On the other hand, the resistance in the high resistance state (HRS) decreased with increasing the device size, and the conduction mechanism in the HRS was explained by Schottky emission.

Basal Cell Carcinoma Arising in a Eyebrow Tattoo

( Seong Hyun Park ),( Ji Hyun Yi ),( Seung Yong Lee ),( Jin Seok Hong ),( Seok Kweon Yun ),( Han Uk Kim ),( Chull Wan Ihm ) 대한피부과학회 2006 초록집 Vol.44 No.10