에너지 소모 상한을 고려한 병렬기계 스케줄링

민성호,김현정 한국경영과학회 2022 한국경영과학회 학술대회논문집 Vol.2022 No.6

에너지 소모 상한을 고려한 병렬기계 스케줄링

민성호,김현정 대한산업공학회 2022 대한산업공학회 춘계학술대회논문집 Vol.2022 No.6

Alcohol Dependence, Mortality, and Chronic Health Conditions in a Rural Population in Korea

민성호,Samuel Noh,Jongho Shin,안정숙,Tae Hui Kim 대한의학회 2008 Journal of Korean medical science Vol.23 No.1

To determine the effects of excessive drinking and alcohol dependency on mortality and chronic health problems in a rural community in South Korea, this study represents a nested case-control study. In 1998, we conducted the Alcohol Dependence Survey (ADS), a population survey of a village in Korea. To measure the effects of alcohol on chronic health conditions and mortality over time, in 2004, we identified 290 adults from the ADS sample (N=1,058) for follow-up. Of those selected, 145 were adults who had alcohol problems, either alcohol dependence as assessed in the ADS by the Severity of Alcohol Dependence Questionnaire (N=59), or excessive drinking without dependency (N=86). Further 145 nondrinkers were identified, matching those with alcohol problems in age and sex. We revisited the village in 2004 and completed personal interviews with them. In multivariate logistic regressions, the rates of mortality and morbidity of chronic health conditions were three times greater for alcohol dependents compared with the rate for nondrinkers. Importantly, however, excessive drinking without dependency was not associated with the rates of either mortality or morbidity. Future investigations would benefit by attending more specifically to measures for alcohol dependence as well as measures for alcohol consumption.

왜, 자살시도자 사례관리인가?

민성호 한국정신건강사회복지학회 2015 한국정신건강사회복지학회 학술발표논문집 Vol.2015 No.10

니코틴성 아세틸콜린 수용체에 미치는 알코올의 영향

민성호,공인덕,차승규,신정호 대한정신약물학회 2006 대한정신약물학회지 Vol.17 No.1

Objective: It has been well known that alcohol can modulate several ligand-gated ion channel and voltage-gated ion channels. But the roles of alcohol in the autonomic neurons still remain unclear. In this study, thus we characterized the neuronal acetylcholine receptor(nnAChRs) and investigated the modulation of nnAChRs by ethanol(EtOH). Methods: We used whole-cells which were acutely dissociated male rat major pelvic ganglion(MPG) neurons, and used gramicidin perforated patch clamp techniques Results: MPG neurons can be classified on the basis of the response of the soma membrane to depolarizing current pulses; either tonic or phasic neurons. Sympathetic neurons expressing T-type Ca2+ channels showed tonic firing pattern, while parasympathetic neurons lacking T-type Ca2+ channels phasic firing to depolarizing current pulses. When hyperpolarizing currents were injected, sympathetic neurons produced post-anodal rebound spikes, while parasympathetic neurons were silent. Under current clamp mode, Acetylcholine(ACh) evoked significant membrane depolarization and produced subsequently marked membrane hyperporization. Under whole-cell mode, application of ACh-induced inward currents held at holding potentials below 0 mV and reversal potential was close to 0 mV, an equilibrium potential of non-selective cation channel. The ACh-activated current was blocked by methyllycaconitine(MLA; 10 μM), hexamethonium(100 μM) and α-bungarotoxin(α-BuTx; 100 nM), nAChRs antagonists. EtOH(40 mM) potentiated ACh-induced depolarization and hyperpolarization. EtOH also increased both α-BuTx-sensitive and -insensitive ACh-activated currents. Futhermore, EtOH potentiated 5-HT-activated current but had a little effect on GABA-activated current. Conclusions: These results suggest that EtOH modulates nnAChRs and 5-HT receptors in MPG neurons. 목 적:니코틴성 아세틸콜린(acetylcholine;ACh) 수용체의 특성과 알코올이 수용체에 미치는 영향을 알아보았다. 방 법:흰쥐 주 골반 신경절(MPG) 신경세포에서 막전압 및 막전류 고정법을 이용하였다. 결 과:MPG 신경세포들은 T-형 Ca2+ 전류의 존재 유무, 지속적인 탈분극 자극에 대한 활동전압 형성의 적응정도, 장시간의 과분극 자극 후의 anode break firing 현상의 발현유무에 따라, 교감신경세포군과 부교감신경세포군으로 나누어져 있다. ACh에 의한 MPG 신경세포의 막전압은 초기의 일시적인 탈분극과 뒤이은 지속적인 과분극의 bipha sic한 변화를 나타냈으며, 막전위는 ACh의 농도에 의존적이었다. ACh에 의해 활성화된 전류는 니코틴성 ACh 수용체 차단제에 의해 억제되었다. ACh과 에탄올을 MPG 신경세포에 동시에 투여하면, ACh을 단독으로 투여했을 때보다 탈분극이 증가되었고, 탈분극 후의 과분극도 증가되었다. MPG 신경세포에 ACh과 에탄올을 동시에 가하였을 경우 ACh에 의한 내향성 전류가 증가되었다. MPG 신경세포에서 에탄올은 GABA 전류에 영향을 미치지 못하였으나, 5-HT에 의한 내향성 전류는 증가시켰다.

외상성 뇌손상 아동의 신경정신과적 후유증 평가

민성호,방형석,왕미란,안정숙,박광수,김혜경,박기창 대한소아ㆍ청소년정신의학회 1999 소아청소년정신의학 Vol.10 No.2

음주관련 범법자 대상 알코올프로그램

민성호(Seongho Min):신정호(Jongho Shin):박새한(Sae-Han Park),안정숙(Joung-Sook Ahn) 한국중독정신의학회 2002 중독정신의학 Vol.6 No.2

In Korea, the alcohol program for alcohol related offenders started in 1997, the model of which was Attendance Centre Orders of U.K that is group-lecture centered with an emphasis on ethics and moral concepts of drinking. The aim of this study was to investigate the effect of our modified alcohol program practiced since February 2001. Our program was long-term follow-up program and emphasized group discussion, which made those offenders get motivation of abstinence and rebuild their attitude toward drinking. We worked with 8-10 offenders each term, total 50 offenders in 6 terms, for 2 hours at once and up to 20 hours for completion of the program. During the program, six scales were used to measure their behavioral change, and expiratory alcohol concentration was tested regularly. The mean age of the subjects was 41 and most of them were married and irreligious. The mean occasion of unearthed driving and other unearthed offence while alcohol intoxication was 2.5 and 1.3, separately. Seventy-six percent of them were suffered with alcohol use disorder and 29% were alcohol dependence. As completing of the program, their amount of alcohol consumed reduced from 1 bottle of Soju before to 0.46 bottle, and the frequency of drinking day lessened from 1 per 2.3 days before to 1 per 4.2 days. But their urge and craving for drinking was not changed significantly, which means the probability of relapse is so high that further long-term followup program is still necessary. From the results of our study, we suggest the alcohol program should be done under the concept of disease of alcohol drinking and treatment order system.

정신분열병 환자에서 지연성 운동장애와 양성, 음성 증후군과의 관련성

민성호,조두영,유범희 大韓神經精神醫學會 1995 신경정신의학 Vol.34 No.6

Object : The authors investigated the association between tardive dyskinesia and positive and negative syndrome in schizophrenia. Method : Eighty-two inpatients who satisfied DSM-Ⅲ-R criteria for schizophrenia and were given antipsychotic medication for more than two years were rated for positive and negative syndromes with the Postive and Negative Syndromc Scale(PANSS) as well as cognitive state with the Mini-Mental State Examination(MMSE). The subjects comprised 41 patients meeting Schooler & Kane's criteria for tardive dyskinesia and 41 age- & gender-matched control patients without tardive dyskinesia. Results : Statistically significant associations were found between tardive dyskinesia and negative syndrome, especially in female schizophrenic patients, bur there was no association between tardive dyskinesia and cognitive impairment. Patients with negative syndrome had a lower score in MMSE and a higher score in general psychopathology scale of PANSS with statistical significance than those with positive syndrome and intermediate type. Conclusion : Tardive dyskinesia was associated with negative syndrome in schizophrenia and it was suggested that there may be a sexual difference in the etiology of tardive dyskinesia and negative syndrome. Schizophrenics with negative syndrome had more severe cognitive impairment and psychopathology compared to those with positive syndrome or intermediate type, possibly due to their early onset and longer duration of illness.

수면 소리 특징과 컨볼루션 신경망을 이용한 상태 분류 모델

민성호(Seongho Min),최예신(Ye Shin Choi),김우제(Woo Jae Kim),이수안(Suan Lee) 한국정보과학회 2023 한국정보과학회 학술발표논문집 Vol.2023 No.12

일 종합병원 정신과 입원환자에서의 Propranolol 사용(I)

민성호,박진환,신정호 大韓神經精神醫學會 1992 신경정신의학 Vol.31 No.1

This report was designed to investigate the propranolol use in a psychiatric in-patients unit. All of the patients who had admitted to the department of psychiatry of Yonsei University. Wonju Christian Hospital, from Jan. 1st to Dec. 31st 1990. were included in this investigation. The propranolol was prescribed in the 107 patients (69male patients and 38 female patients) among the total 147 patients. The results were as the followings : 1) The propranolol was prescribed in 23.9% of the 447 patients. 2) The patients whose initial daily dosage of the propranolol was between 40mg and 80mg. were 77.6% of the total patients, and the average dosage was 52.1±24.4mg. 3) The daily dosage of the prescribed propranolol ranged from 20mg to 440mg. The maximal dosage was 106.6±82.2mg/ 4) Schizophrenia was the highest diagnostic group(37.4%) among all DSM-III-R diagnostic distribution in the patients with the propranolol. 5) Symptom improvement was the main reason of limited-increase pattern of administration(46.7% ). 35 patients failed to continue propranolol use. 22 patients(62.9% ) among them had stopped propranolol use because of some kind of side effects. 6) Propranolol was effective in 80.4% of the patients for the target symptoms. 7) The target symptoms for the propranolol use were aggression, anxiety, akathisia, mania. psychosis and tremor. Akathisia(39 patients. 36.4%) was the most frequent reason of propranolol administration, the next was anxiety (30 patients. 28.0%). thereafter aggression(27 patients. 25.2%). The above 3 groups account for almost target symptoms(89.7%). 8) The maximal dosage for aggression was 191.9mg in average, and significantly higher than that for anxiety(98.3mg). akathisia(61.5mg) and tremor(56.0mg). 9) With the target symptoms of the propranolol use. the pattern of propranolol administration varied by one of three modes.