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      • 상엽수확고(桑葉收穫高) 측정(測定)에 관(關)한 연구(硏究) -각형질(各形質) 가중치(加重値)(Weight)에 의(依)한 수량(收量)의 측정(測定)-

        한경수 ( K. S. Han ),장권열 ( K. Y Chang ),안정준 ( J. J. Ahn ) 한국잠사학회 1969 한국잠사곤충학회지 Vol.9 No.-

        상엽의 수확고를 측정하기 위하여 상엽의 수량과 높음 상관관계가 있는 형질 중 상전에서 쉽게 측정할 수 있는 기조장(X1), 기조직경(X2), 엽수(X3), 엽면적(X4)의 4개 형질을 측정하여 이들 형질의 수량에 영향하는 가중치를 다중회분방정식에 의하여 산출하여 수량을 측정할 수 있도록 여러 가지 식을 유도하였다. 1. 기조장(X1)과 기조직경(X2)을 측정하여 수량을 측정하기 위하여는 개량서반에 있어서는 y1v1=-1.15760+0.068X1+165.756X2(g) 일지뢰에 있어서는 y1v2=-221.500+1.768X1+38.152X2(g) 노상에 있어서는 y1v2=-253.826-0.116X1+289.507X(g) 수원상 4호에 있어서는 y1v4=-157.559+1.063X1+106.088X2(g)의 식에 의해서 기조장(X1)과 기조직경(X2)의 측정치를 대입하면 수량을 견적할 수 있다. 2. 기조장(X1), 기조직경(X2), 엽수(X3)의 3개 형질을 측정하여 수량을 견적하는 데는 각품종별로 각각 y2v1=-118.478-0.665X1+184.445X2+2.346X3 y2v2=217.432+2.062X3+35.668X2-1.058X3 y2v3=-206.249-0.739X1+268.08X2+2.770X3 y2v4=-153.383+0.009X1+2.024X2+0.171X3의 식에 의하여 수량을 견적할 수 있다. 3. 기조장(X1), 기조직경(X2), 엽수(X3), 엽면적(X4)의 4개 형질을 측정하고 수량을 견적하기 위하여는 각품종별로 각각 y11v1=82.567-1.283X1+15.501X2+0.640X3+3.511X4 y11v2=136.411+0.311X1+1.921X2-0.217X3+0.214X4 y11v3=150.2Z7-0.139X1+11.788X2+0.143X3+0.381X4 y11v4=160.850+0.323X1+66.076X2-0.794X3+2.614X4 등의 식에 의하여 수량을 견적할 수 있다. Various formulae for estimation of leaf production in mulberry trees were investigated and obtained. Four varieties of mulberry trees were used as the materials, and four characters, namely branch length (X, 1), branch diameter (X, 2), leaf number per branch (X, 3), and leaf area per branch (X, 4), were studies. The formulae to eatimate the leaf yield of mulberry trees are as follows: 1. Y1v1=-115.760+0.068X1+165.756X2 Y1v2=-221.500+1.768X1+38.152X2 Y1v8=-253.826-0.116X1+289.507X2 Y1v4=-157.559+1.063X1+106.088X2 where Y1v1, Y1v2, Y1v3, Y1v4, are showed the estimated yield of the each variety, namely Gaeryang souban, Ilchirye, Nosang, and Suwon Sang No. 4, respectively. X2 and X2 denote the measured values of branch length and branch diameter, respectively. 2. Y2v1=-118.478-0.665X1+184.445X2+2.346X3 Y2v2=-217.432+2.062X1+35.668X2-1.058X3 Y2v3=-206.249-0.739X1+268.08X2+2.770X3 Y2v4=-153.383+0.009X1+2.024X2+0.171X3 where Y2v1, Y2v2, Y2v3, Y7v4, are the estimated yield of the each variety, namely Gaeryang. Souban, Ilchirye, Nosang, and Suwon Sang No. 4, respectively. X1, X2, X3, denote the measured values of each character, branch length, branch diameter and leaf number per branch, respectively. 3. Y11v1=82.567-1.283X1+15.501X2+0.640X3+3.511X4 Y11v2=136.411+0.311X1+1.921X2-0.217X3+0.214X4 Y113v=150.227-0.139X1+11.788X2+0.143X3+0.381X4 Y11v4=-160.850+0.323X1+66.076X2-0.794X3+2.614X4 where Y11v1, Y11v2, Y11v3, Y11v4, are the estimated yield values of four varieties, and X1, X2, X3, X4 denote the measured values of four characters, namely branch length, branch diameter, leaf number per branch and leaf area per branch, respectively. The estimation method of mulberry leaf yield by measurement of some characters, branch length, branch diameter, leaf number per branch and leaf area per branch, could be the better method to determine the leaf yield of mulberry trees without destroying the leaves and without weighting the leaves of mulberry trees than the other methods.

      • 1987년 한국에서 발생한 렙토스피라병의 혈청역학적 조사

        이증훈,박영수,이우곤,김석용,정선식,우준희,박성광,박경희,송영욱,김선영,기정일,최두혁,강성귀,김주완,최강원,김우열,최명식,최인학,장우현,윤성열 대한감염학회 1988 감염 Vol.20 No.3

        Human leptospirosis was an unfamiliar disease in Korea until 1984 that outbreak of leptospirosis occurred among farmers and soldiers after field works for harvesting rice. During that time, Lee and Jo confirmed the first Korean cases of leptospirosis by serological test, isolation of causative agent and autopy findings. Afterward several outbreaks occurred also during autumn especially after flood in every years and some characterisitcs of leptospirosis in Korea such as clinical manifestations, serotypes and seroepidemiological features has been revealed by many investigators. Because of the major mode of transmission between rodents and human is by direct contact with leptospiral urine of rodents or contaminated soil by the urine, leptospirosis in Korea has been primarily a disease of person in occupations heavily exposed to contaminated soil or infected urine such as farmer, army and etc. Therefore it seems that leptospirosis is one of the main communicable diseases to be controlled urgently in Korea, for an agricultural people account for almost half of total Korean people. For clarifying the seroepidemiological patterns of human leptospirosis in Korea by sex, month region and main reacting serovars of L. interrogans among acute febrile disease occurred in 1987, 1,773 patient's sers with acute febrile episodes were tested by microagglutination test using 19 representative strains of leptospiral serogroup as antigen. All of those sera were collected from 10 collaborative clinics located in Kyunggi, Kangwon, Chungbuk, Chungnam, Chonbuk, Chonnam province and Seoul. The results wee summerized as follows. 1) Among 1,773 sera of patients with acute febrile episodes, 219 (12.4%) were seropositive to L. interrogans, 487(27.5%) to R. tsutsugamushi, 241(13.6%) to R.typhi and 160(90.0%) to Hantaan virus. 2) Among seropositives to L.interrogans, the male outnumbered the female, 65% and 35%. 3) For age distribution, 26.9% of seropositives to L.interrogans were fifties, 19.6% were forties, 9.1% were sixties, 5.9% were thirties and 4.1% were twenties. 4) Eighty three percent of seropositives had occurred between September and October in 1987 with a peak in September. 5) Main leptospiral serovars reactive to patient's sera were Icterohaemorrhagiae(54.3%), Canicola(31.0%), CH-48(13.2%), Tarassovi(0.9%)and Cynopteri(0.5%). 6) For regional distribution, 65.8% of seropositives to L.interrogans were residents from Chonbuk, 12.3% were Chonnam, 7.3% were Chungnam, 5.5% were Kyunggi and 1.4% were Kangwon.

      • Modeling and simulation of HTS cables for scattering parameter analysis

        Bang, S.S.,Lee, G.S.,Kwon, G.Y.,Lee, Y.H.,Chang, S.J.,Lee, C.K.,Sohn, S.,Park, K.,Shin, Y.J. North-Holland 2016 Physica. C, Superconductivity Vol.530 No.-

        <P>Most of modeling and simulation of high temperature superconducting (HTS) cables are inadequate for high frequency analysis since focus of the simulation's frequency is fundamental frequency of the power grid, which does not reflect transient characteristic. However, high frequency analysis is essential process to research the HTS cables transient for protection and diagnosis of the HTS cables. Thus, this paper proposes a new approach for modeling and simulation of HTS cables to derive the scattering parameter (S-parameter), an effective high frequency analysis, for transient wave propagation characteristics in high frequency range. The parameters sweeping method is used to validate the simulation results to the measured data given by a network analyzer (NA). This paper also presents the effects of the cable-to-NA connector in order to minimize the error between the simulated and the measured data under ambient and superconductive conditions. Based on the proposed modeling and simulation technique, S-parameters of long-distance HTS cables can be accurately derived in wide range of frequency. The results of proposed modeling and simulation can yield the characteristics of the HTS cables and will contribute to analyze the HTS cables. (C) 2016 Elsevier B.V. All rights reserved.</P>

      • RF Interference Analysis for KOMPSAT-II Spacecraft

        Lim, S.B.,Kim, D.Y.,Chang, Y.K. 통신위성우주산업연구회 2001 Joint Conference on Satellite Communications Vol.2001 No.-

        In general, LEO satellite uses S-band communication link for the whole satellite management, whereas the satellite payload frequently implements X-band and/or Ku-band transmitter for payload data transmission. The transmission system should have out-band rejection filter (protection circuit) to prevent any interference with the satellite receiver, so that the receiver can be normally operated. It is usually implemented in the transmitter itself but the vendor of a transmitter could not take it into account whole out of band frequency because a variety of individual satellites utilize different RF communication systems. The KOMPSAT-II, which is an earth observation satellite, is being developed by Korea Aerospace Research Institute and Korean industries. It has S-band communication system for the bus and X-band transmission system for payload data. In addition, L-band GPS Receiver is being incorporated to achieve the KOMPSAT-II mission goal. Unfortunately, the KOMPSAT-2 payload system does not have external out-band rejection~ filter nor transmitter for S-band and L-band protection. The transmitter only has band rejection filter for TDRSS. In addition, it has high gain directional antenna whose directional beam has to pass over the S-band antenna. In this paper, the analysis method is described to calculate the interference effects of the S-band spurious noise power on X-band transmitting system to S-band receiver. The S-band antenna is positioned very closely to the X-band Antenna by I .2m. We will also introduce general simple RF interference analysis method applicable to a traditional system, including advantage and disadvantages. The X-band transmitting system is often required to add the specified filter to suppress the S-band spurious signal for the safety of the receiver performance. The analysis result shows that the performance of S-band receiver is satisfied with no implementation of the specified filter.

      • 충청지역에서 발생한 쭈쭈가무시병의 임상상, 원인균의 혈청형 및 혈청역학적 연구

        김선영,김윤성,박장규,윤태영,강재승,송인숙,최명식,최인학,차창룡,이우곤,박종우,이증훈,장우현,유영해,윤광혁,송계용 대한감염학회 1989 감염 Vol.21 No.2

        From September to december 1987, eighty-six cases of tsutsugamushi disease were diagnosed by indirect immunofluorecent test or by isolating the causative agent in Chungcheung area. Their clinical features and patterns of antibody response to R. tsutsugamushi were analyzed. For the indenfication of prevalent antigenic types of R. tsutsugamushi in Chungcheung area, twenty-seven strains isolated were tested by indirect immunofluorescent test. To assess the extent of exposure to R.tsutsugamushi of a general population in Korea, the prevalence of antibody was investigated in 6,572 sera obtained from the residents of Chungcheung area by indirect immunofluorescent test. The female patients slightly outnumbered the male patients. More cases (68%) were older than 40 years of age. The epidemic peaked in October. The mean incubation period estimated was about 8 days. The major clinical features were fever and chill, headache, rash, eschar, and lymphadenopathy. Increased serm transaminase was the most singificant laboratory findings. Abnormalities in the chest roentgenography were often observed. The antibody titer rose rapidly 5 days after the onset, reached its peak at 20 days (1:640), and then declined agradually until 7 months(1:20). The seroype of 23 out of the 27 isolates wase found to be karp, one was Gilliam, and 3 isolates could not be classified by using polyclonal mouse hyperimmune sera. The prevalence of antibody to R.tsutsugamushi in the residents of Chungcheung area was 4.8%. The prevalence of antibody was higher in the female than in the male. The prevalence was higher in the residents of age above 40 years than below 40 years, and was the lowest in the children less than 10 years of age. Of the 318 positive sera from normal residents, only 2 sera showed the titers higher than 1:80.

      • KCI등재

        Carbon nanotube-based biosensor for detection of matrix metallopeptidase-9 and S-100B

        Lee, H.S.,Oh, J.S.,Chang, Y.W.,Park, Y.J.,Shin, J.S.,Yoo, K.H. 한국물리학회 2009 Current Applied Physics Vol.9 No.4_SUP

        We fabricated carbon nanotube (CNT)-based biosensor with field effect transistor structure for detection of matrix metallopeptidase-9 (MMP-9) and S-100B. To minimize contact effects, the metal electrodes were passivated with SiO<SUB>x</SUB> film, and anti-MMP-9 and S-100B antibody were immobilized on the CNT surface using a chemical linker. When MMP-9 or S-100B antigen was added to bind anti-MMP-9 or S-100B antibody, the decrease in electrical conductance was observed. We have also investigated the dependence of MMP-9 and S-100B concentration on the conductance change. A linear relationship was found between the conductance and the concentration in semi-logarithm scale.

      • Temperature and air pollution affected tree ring δ<sup>13</sup>C and water-use efficiency of pine and oak trees under rising CO<sub>2</sub> in a humid temperate forest

        Kwak, J.H.,Lim, S.S.,Lee, K.S.,Viet, H.D.,Matsushima, M.,Lee, K.H.,Jung, K.,Kim, H.Y.,Lee, S.M.,Chang, S.X.,Choi, W.J. Elsevier 2016 Chemical geology Vol.420 No.-

        <P>To better predict forest productivity under rising atmospheric CO2 concentration ([CO2]), it is critical to understand how intrinsic water-use efficiency (WUEi) and its relationship with tree growth are affected by the concomitant changes in environmental conditions such as precipitation, temperature, and air pollution that either enhance or undermine any potential CO2 fertilization effect. We investigated changes in delta C-13 and WUEi in annual rings and basal area increment (BAI) of Pinus densiflora (from 1968 to 2007) and Quercus variabilis (from 1970 to 2007) trees in relation to precipitation, temperature, and air pollution in a humid temperate forest. The WUEi of P. densiflora increased by 39.9%, whereas that of Q. variabilis did not change over time in the study period. The WUEi was not affected by precipitation for both species but increased (P < 0.001) with temperature for P. densiflora and with SO2 emissions for both species. Multiple regression models suggested that the effect of [CO2] on tree growth was much higher than temperature; however, for the period (1998 to 2007) when SO2 emissions data were available, SO2 emission was the driver of changes in BAI and WUEi, and temperature effects became stronger than [CO2]. Overall, BAI and WUEi were positively (P < 0.001) correlated for P. densiflora, but not for Q. variabilis. We conclude that temperature and air pollution rather than precipitation were key determinants of WUEi at the study site and that the two species had contrasting responses to environmental changes. (C) 2015 Elsevier B.V. All rights reserved.</P>

      • 한국 농촌거주 정상인의 Leptospira Interrogans에 대한 항체보유율 현황

        최강원,최성배,국윤호,장우현,우준희,박경희,강재승,차창룡,김양수,김석용,윤종구,김익상,이우곤,최명식,송영욱 대한감염학회 1988 감염 Vol.20 No.3

        It has been well known that leptospiroisis is a one of the prevailing acute febrile diseases in Korea. In order to find out the incidence of past infection of L. interrogans among normal population, a total of 1,171 sera obtained from rural residents and tested by microscopic agglutination test. All of normal resident's sera were collected during July in 1987, just before epidemic season, at Keochang county(248 sera), at Wanju county(145 sera), at Wonseoung county(255 sera), at Cholwon county(411 sera) and at Kongju county(112 sera). Seropositive rate against L. interrogans among rural residents was 12.0% and ranged from 2.7% in Kongju county to 18.5% in Cholwon county. There was a higher seropositive rate in males and the majority of seropositives occurred in the age group over 30 yesrs. Icterohaemorrhagiae was a most commonly reacting serotype of L. interrogans and followed by CH-48 and Canicola. The sera reacted with Cynopteri, Ballum, Australis, and Pyrogenes were present also.

      • SCISCIESCOPUS

        Progress in the development of heating systems towards long pulse operation for KSTAR

        Kwak, J.G.,Bae, Y.D.,Chang, D.H.,Chang, D.S.,Hong, B.G.,Hwang, C.K.,In, S.R.,Jeong, S.H.,Jin, J.T.,Jung, K.S.,Kim, B.R.,Kim, J.,Kim, S.K.,Kim, T.S.,Lee, D.W.,Lee, K.W.,Oh, B.H.,Seo, C.S.,Seo, M.S.,Yoo International Atomic Energy Agency 2007 Nuclear fusion Vol.47 No.5

        <P>Construction of the Korea superconducting tokamak advanced research (KSTAR) tokamak is in its final phase. For the long-pulse KSTAR discharges, the ion cyclotron range of frequencies (ICRF) and neutral beam injection (NBI) heating systems are expected to play important roles through a selective heating of ions and electrons, control of the plasma pressure and current profiles, a core fuelling and beam diagnostics for the KSTAR. In addition, the ICRF system is expected to be used for possible discharge cleaning and assisting in the tokamak startup. In this paper, the recent progress in the development of the ICRF and the NBI heating systems is described. The four-strap ICRF antenna has been successfully tested for a voltage up to 41 kV for a pulse length of 300 s (to 46 kV for 20 s) in a test chamber. A prototype KSTAR NBI system has been developed. At present, the system has successfully produced a 1 MW beam power for 200 s and a 3.5 MW output beam power for 4 s.</P>

      • SCISCIESCOPUS

        Phase II study of S-1 combined with oxaliplatin as therapy for patients with metastatic biliary tract cancer: influence of the <i>CYP2A6</i> polymorphism on pharmacokinetics and clinical activity

        Kim, K-p,Jang, G,Hong, Y S,Lim, H-S,Bae, K-s,Kim, H-S,Lee, S S,Shin, J-G,Lee, J-L,Ryu, M-H,Chang, H-M,Kang, Y-K,Kim, T W Nature Publishing Group 2011 The British journal of cancer Vol.104 No.4

        <P><B>Background:</B></P><P>Advanced biliary cancer is often treated with fluoropyrimidine-based chemotherapy. In this study, we evaluated the efficacy and tolerability of a combination of S-1, an oral fluoropyrimidine prodrug, and oxaliplatin in patients with metastatic biliary cancer.</P><P><B>Methods:</B></P><P>Patients with histologically confirmed metastatic biliary cancer and no history of radiotherapy or chemotherapy were enrolled. Oxaliplatin was administered intravenously (130 mg m<SUP>−2</SUP>), followed by 14-day administration of oral S-1 (40 mg m<SUP>−2</SUP> twice daily) with a subsequent 7-day rest period every 21 days. Pharmacokinetic analysis of S-1 was performed at cycle 1. Patients were genotyped for <I>CYP2A6</I> polymorphisms (<SUP>*</SUP>1, <SUP>*</SUP>4, <SUP>*</SUP>7, <SUP>*</SUP>9 or <SUP>*</SUP>10), and pharmacokinetic and clinical parameters compared according to the <I>CYP2A6</I> genotype.</P><P><B>Results:</B></P><P>In total, 49 patients were evaluated, who received a median of four cycles. The overall response rate was 24.5%. Median progression-free and overall survival was 3.7 and 8.7 months, respectively. The most common haematological grade 3 out of 4 toxicity was neutropenia (14%), while non-hematological grade 3 out of 4 toxicities included anorexia (14%), nausea (12%), asthenia (10%), vomiting (10%), and diarrhoea (4%). Biotransformation of S-1 (AUC<SUB>0−24 h</SUB> of 5-fluorouracil/AUC<SUB>0−24 h</SUB> of tegafur) was 1.85-fold higher for the <I>*1/*1</I> group than for the other groups (90% confidence interval 1.37–2.49). Diarrhoea (<I>P</I>=0.0740), neutropenia (<I>P</I>=0.396), and clinical efficacy (response rate, <I>P</I>=0.583; PFS, <I>P</I>=0.916) were not significantly associated with <I>CYP2A6</I> genotype, despite differences in 5-FU exposure.</P><P><B>Conclusion:</B></P><P>The combination of S-1 and oxaliplatin appears to be active and well tolerated in patients with metastatic biliary cancer, and thus is feasible as a therapeutic modality. <I>CYP2A6</I> genotypes are associated with differences in the biotransformation of S-1. However, the impact of the <I>CYP2A6</I> polymorphism on variations in clinical efficacy or toxicity requires further evaluation.</P>

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