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Yingmei Wang,Shiqian Zhang,Lihui Wei,Zhongqiu Lin,Xinyu Wang,Jianliu Wang,Keqin Hua,Manhua Cu,Jiandong Wang,Shixuan Wang,Wen Di,Yudong Wang,Ruifang An,Mingrong Xi,Ruixia Guo,Qi Zhou,Xing Xie,Fengxia X 대한부인종양학회 2020 Journal of Gynecologic Oncology Vol.31 No.4
The outbreak of coronavirus disease 2019 (COVID-19) caused by the severe acute respiratorysyndrome coronavirus 2 has rapidly spread globally. Cancer patients are at a higher risk ofbeing infected with the coronavirus and are more likely to develop severe complications, ascompared to the general population. The increasing spread of COVID-19 presents challengesfor the clinical care of patients with gynecological malignancies. Concerted efforts should beput into managing gynecological malignancies in an orderly manner by strictly implementingthe measures that are specifically developed for controlling the spread of COVID-19. We havedrafted Recommendations on Management of Gynecological Malignancies during the COVID-19 Pandemicbased on our experience on controlling COVID-19 pandemic in China. We recommendthat patients with gynecological malignancies should be managed in hierarchical andindividualized manners in combination with local conditions related to COVID-19. Medicalcare decision should be balanced between controlling COVID-19 pandemic spread and timelydiagnosis and treatment for gynecologic oncology patients.
Spectral Analysis of the Moving System with Multi-object Based on V-system
Ruixia Song,Chenghua Li,Xiaochun Wang,Yena Wang,Yanqing Xu,Dongxu Qi (사)한국CDE학회 2013 한국CAD/CAM학회 국제학술발표 논문집 Vol.2010 No.8
Based on an orthogonal function system over triangular domain, V-system, decomposing orthogonally a moving system with multiple moving objects into V-series, motion state of this moving system at different moment can be expressed in the frequency domain. To make full use of the advantage of the V-system, the capability to precisely express a 3D object group, each moving object is represented by a triangular mesh model, and then the energy curve data for the moving system is calculated by determining the coefficients of the V-series. The energy curve can be applied to the state analysis of the moving system. The relationship of energy curves of a moving system with different triangular mesh resolutions is analyzed. The experiment results show that there exist no strong dependence between energy curve and the resolution of 3D model, so when performing spectral analysis for a moving system, we can choose the model with low resolution, so that the computation can be reduced and the analysis efficiency can be improved. Finally, the mathematic relationship between energy of a moving system and some related variables is obtained by processing a large number of experimental data using the linear regression method. The characteristic of this study is reflected in the whole expression of a 3D model group, and the objects in the group are in motion.
( Ruixia Liu ),( Yinglong Wang ),( Minglei Shu ),( Huiqi Zhao ),( Changfang Chen ) 한국인터넷정보학회 2018 KSII Transactions on Internet and Information Syst Vol.12 No.11
The coexisting wireless body area networks (WBAN) is a very challenging issue because of strong inter-networks interference, which seriously affects energy consumption and spectrum utilization ratio. In this paper, we study a power control strategy with nearest neighbor nodes distribution for coexistingWBAN based on stochastic geometry. Using homogeneous Poisson point processes (PPP) model, the relationship between the transmission power and the networks distribution is analytically derived to reduce interference to other devices. The goal of this paper is to increase the transmission success probability and throughput through power control strategy. In addition, we evaluate the area spectral efficiency simultaneously active WBAN in the same channel. Finally, extensive simulations are conducted to evaluate the power control algorithm.
Inhibition of glutathione metabolism attenuates esophageal cancer progression
Liang Peng,Ruixia Linghu,Demeng Chen,Jing Yang,Xiaoxue Kou,Xiang-Zhen Wang,Yi Hu,Yi-Zhou Jiang,Junlan Yang 생화학분자생물학회 2017 Experimental and molecular medicine Vol.49 No.-
Esophageal squamous cell carcinoma (ESCC) is a deadly malignancy with regard to mortality and prognosis, and the 5-year survival rate for all patients diagnosed with ESCC remains poor. A better understanding of the biological mechanisms of ESCC tumorigenesis and progression is of great importance to improve treatment of this disease. In this study, we demonstrated that the glutathione metabolism pathway is highly enriched in ESCC cells compared with normal esophageal epithelial cells in an in vivo mouse model. In addition, treatment with L-buthionine-sulfoximine (BSO) to deplete glutathione decreased the ESCC tumor burden in mice, thus demonstrating the critical role of glutathione metabolism in ESCC progression. BSO treatment also led to decreased cell proliferation and activation of cell apoptosis in ESCC. Finally, BSO treatment blocked NF-kB pathway activation in ESCC. Our study reveals a new pathway that regulates ESCC progression and suggests that inhibition of glutathione metabolism may be a potential strategy for ESCC treatment
Multiwavelets over a Triangular Domain
Jian Li,Ruixia Song,Xiaochun Wang,Dongxu Qi (사)한국CDE학회 2010 한국CAD/CAM학회 국제학술발표 논문집 Vol.2010 No.8
Employing barycentric coordinates, this paper propose a kind of orthogonal muliwavelet over a triangular domain, called V-system. The V-system consists of not only smooth functions but also functions with discontinuities. Finitely terms of the V-system can exactly represent the geometric objects which can be expressed by a piecewise polynomials. Since barycentric coordinates are a fundamental tool for dealing with the case of triangles, and the expressions of the basic functions of the V-system in baycentric coordinates have short support, orthogonality, symmetry and vanishing moments, so the system is more concise and convenient to be used to realize orthogonal decomposition for the complex geometry models in CAGD. Especially, the geometry model composed of several separate parts can be exactly reconstructed, which can’t be realized by other continuous wavelets. The orthogonal decomposition provides theoretic fundament for feature extraction and further classification and shape retrieval. Experiment results show that this method is feasible and easy to use, and it worth being extended.
Degradation Characteristics and Metabolic Pathway of 17β-estradiol (E2) by Rhodococcus sp. DS201
Qingmiao Yu,Ping Wang,Dongbo Liu,Ruixia Gao,Huanhuan Shao,Hongyan Zhao,Zhe Ma,Dan Wang,Hongliang Huo 한국생물공학회 2016 Biotechnology and Bioprocess Engineering Vol.21 No.6
In this study an E2-degrading bacterium was isolated from the activated sludge of a municipal treatment plant that treats the waste from a contraceptive medicineprocessing factory in Beijing, China. Using the observed morphological and physiological features of the bacterium and 16S rRNA sequence analysis, this bacterial strain was identified as Rhodococcus sp. DS201. Using single-factor experiments and orthogonal tests, it was demonstrated that, when strain DS210 bacteria were inoculated into MM medium at an initial concentration of 1 mg/L with an initial pH of 7 and an inoculum amount of 1%, complete degradation of E2 by this strain was achieved within 3 days at 30oC. After strain DS201 had degraded the E2, several E2 metabolites were detected in the culture extracts using high-performance liquid chromatography (HPLC); they were then further identified using HPLC with tandem mass spectrometry (LC-MS/MS). Mass spectrum analysis of the E2 degradation identified the following products: pent- 4-enoic acid; 2-ethyl-3-hydroxy-6-methylcyclohexane-1- carboxylic acid; 3-(7a-methyl-1,5-dioxooctahydro-1H-inden- 4-yl) propanoic acid; and 5-hydroxy-4-(3-hydroxypropyl)- 7a-methyloctahydro-1H-inden-1-one. These products have not previously been reported as parts of a mechanism for microbial E2 degradation and were suspected to be new metabolite products. Therefore, the E2 degradation pathway by strain DS201 is proposed herein.
Yan Xian-Tao,Zhang Ziqi,Wang Yubao,Zhang Wenmiao,Zhang Longfei,Liu Yang,Chen Dawei,Wang Wenqiong,Ma Wenlong,Qian Jian-Ya,Gu Ruixia 한국응용생명화학회 2023 Applied Biological Chemistry (Appl Biol Chem) Vol.66 No.-
The ability of natural plants to treat chronic diseases is closely related to their antioxidant function. Lactic acid bacteria (LAB) fermentation is an effective way to improve the nutritional value, biological activity and flavor of food. This study investigated the pH, titratable acidity, total polysaccharide, total flavone, total saponin, total polyphenol, and antioxidant activity of the FH06 beverage before and after probiotic fermentation. Results: After fermentation, FH06 had lower contents of total polysaccharides, total flavonoids, total saponins and total polyphenols but higher titratable acidity. The antioxidant activity was tested by total antioxidant capacity (FRAP method) and DPPH· scavenging ability. The FRAP value significantly increased after fermentation (P < 0.05), and the maximum increase was observed for Lactobacillus fermentum grx08 at 25.87%. For DPPH· scavenging ability, the value of all fermentations decreased, and L. fermentum grx08 had the smallest reduction at 2.21% (P < 0.05). The results of GC–MS and sensory analysis showed that fermentation eliminated bad flavors, such as grass, cassia and bitterness, and highlighted the fruit aroma and soft sour taste. Conclusion: The FRAP value and sensory flavor of FH06 fermentation by L. fermentum grx08 were significantly improved, indicating its great potential as a functional food with both strong antioxidant activity and good flavor.