Mechanics of a variable damping self-centering brace: Seismic performance and failure modes

Xing-Si Xie,Long-He Xu,Zhong-Xian Li 국제구조공학회 2019 Steel and Composite Structures, An International J Vol.31 No.2

The force-deformation behavior, strain distribution and failure modes of a variable damping self-centering brace (VD–SCB) are theoretically analyzed, experimentally studied, and numerically simulated to guide its design. The working principle of the brace is explained by describing the working stages and the key feature points of the hysteretic curve. A large-scale brace specimen was tested under different sinusoidal excitations to analyze the recentering capability and energy dissipation. Results demonstrate that the VD–SCB exhibits a full quasi-flag-shaped hysteretic response, high ultimate bearing capacity, low activation force and residual deformation, and excellent recentering and energy dissipation capabilities. Calculation equations of the strain distribution in different parts of the brace are proposed and are compared with the experimental data and simulated results. The developments of two failure modes are compared. Under normal circumstances, the brace fails due to the yielding of the spring blocking plates, which are easily replaced to restore the normal operating conditions of the brace. A brief description of the design procedure of the brace is proposed for application.

Multi-objective optimization design of a centrifugal impeller by positioning splitters using GMDH, NSGA-Ⅲ and entropy weight-TOPSIS

Xing Xie,Zhenlin Li,Baoshan Zhu,Hong Wang,Wenwu Zhang 대한기계학회 2021 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.35 No.5

A centrifugal impeller with splitters was designed by three-dimensional (3D) inverse design method, and its efficiency, velocity non-uniformity at impeller exit and maximum equivalent stress of blades were optimized by providing the suitable blade stacking angle, work ratio and circumferential location of the splitter. First, 80 samples were generated by optimal Latin hypercube technique and the corresponding impellers were designed by 3D inverse design. Using computational fluid dynamics (CFD) and fluid structure interaction (FSI), the optimization objectives were obtained. Then, the group method of data handling (GMDH) artificial neural networks was established to link the design parameters and objectives by the specific formulas. The reference-point-based non-dominated sorting genetic algorithm (NSGA-Ⅲ) was applied to search the Pareto front. Finally, the preferred impeller was selected by adopting entropy weight and the method of technique for order preference by similarity to an ideal solution (TOPSIS). The results showed that the splitter of the preferred impeller had a circumferential location of 0.58, blade stacking angle of 28° and work ratio of 0.48. The nonuniformity at impeller exit and maximum equivalent stress of blades of preferred impeller obtained by NSGA-Ⅲ were decreased, while the efficiency was improved.

ZNF435, a Novel Human SCAN-containing Zinc Finger Protein, Inhibits AP-1-mediated Transcriptional Activation

Xing Gu,Mei Zheng,Xiangwei Fei,Zhenxing Yang,Fan Li,Chaoneng Ji,Yi Xie,Yumin Mao 한국분자세포생물학회 2007 Molecules and cells Vol.23 No.3

A Density Functional Study of Furofuran Polymers as Potential Materials for Polymer Solar Cells

Xie, Xiao-Hua,Shen, Wei,He, Rong-Xing,Li, Ming Korean Chemical Society 2013 Bulletin of the Korean Chemical Society Vol.34 No.10

The structural, electronic, and optical properties of poly(3-hexylthiophene) (P3HT) have been comprehensively studied by density functional theory (DFT) to rationalize the experimentally observed properties. Rather, we employed periodic boundary conditions (PBC) method to simulate the polymer block, and calculated effective charge mass from the band structure calculation for describing charge transport properties. The simulated results of P3HT are consistent with the experimental results in band gaps, absorption spectra, and effective charge mass. Based on the same calculated methods as P3HT, a series of polymers have been designed on the basis of the two types of building blocks, furofurans and furofurans substituted with cyano (CN) groups, to investigate suitable polymers toward polymer solar cell (PSC) materials. The calculated results reveal that the polymers substituted with CN groups have good structural stability, low-lying FMO energy levels, wide absorption spectra, and smaller effective masses, which are due to their good rigidity and conjugation in comparison with P3HT. Besides, the insertion of CN groups improves the performance of PSC. Synthetically, the designed polymers PFF1 and PFF2 are the champion candidates toward PSC relative to P3HT.

Research on Human Driving Characterised Trajectory Planning and Trajectory Tracking Control Based on a Test Track

Xing Xu,Xinwei Jiang,Ju Xie,Feng Wang,Minglei Li 제어·로봇·시스템학회 2023 International Journal of Control, Automation, and Vol.21 No.4

The trajectory planning plays an important role in realizing the autonomous driving process. The trajectory that reflects the driving habits of human drivers and conforms with people’s driving intuition enables a vehicle to operate smoother and more comfortable when passing through corners, which could improve the acceptability of autonomous vehicles in the market in the future. The research of this paper focuses on planning a human driving characterised trajectory along a road based on the test track that could reflect natural driving behaviour in corners considering the sense of natural and comfortable for the occupants. Firstly, the data collected of the test track are processed and the coordinate system transformation is completed, and the human tested trajectories in the test track is extracted and analysed. Then, the human driving characterised trajectory planning is completed based on optimal control in a lane section on the test track. The trajectory tracking control algorithm based on LQR is designed, and a CarSim/Simulink co-simulation platform is established to track the optimal trajectory generated in a lane and the lane centreline trajectory to verify the superiority of the planned trajectory. The results show that compared with the centreline trajectory, the human driving characterised trajectory planned enables the autonomous vehicle operates smoother and more comfortable, and reflects the characteristic of human drivers to a large extent.

Preparation of Chitooligosaccharides from Chitosan using Crude Enzyme of Bacillus cereus D-11

( Xing Ai Gao ),( Yong Feng Zhang ),( Ro Dong Park ),( Xiao Huang ),( Xin Ying Zhao ),( Jiao Xie ),( Rong De Jin ) 한국응용생명화학회 2012 Journal of Applied Biological Chemistry (J. Appl. Vol.55 No.1

In order to enzymatically produce chitooligosaccharide using the crude enzyme preparation from Bacillus cereus D-11, we first studied the optimal reaction conditions. It was found that the optimal temperature for hydrolysis of chitosan was 55oC. The ratio of enzyme/substrate should not be lower than 0.13 U/mg in the reaction mixture. The enzyme activity was stable below 50oC. The products of enzymatic reaction were analyzed by both thin layer chromatography and high performance liquid chromatography. Under the appropriate condition, chitosan was hydrolyzed using the enzyme preparation. The resulting chitooligosaccharides were purified and separated by Dowex (H+) ion exchange chromatography. From 4 g soluble chitosan, 0.95 g (GlcN)2, 1.43 g (GlcN)3, and 1.18 g (GlcN)4 were recovered.

Low Molecular Weight Organic Acids in Brassica pekinensis Rupr. and Growing soil Influenced by Simulated Nitrate Deposition

Xie, Wen-Ming,Liu, Xing-Quan,Ko, Kwang-Yong,Lee, Kyu-Seung The Korean Society of Environmental Agriculture 2008 한국환경농학회지 Vol.27 No.3

We investigated whether carboxylate exudation of Brassica pekinensis Rupr. was affected by nitrate deposition from simulated acid rain. A gas chromatographic (GC) analysis was employed for the determination of low molecular weight organic acids (LOA) in rhizosphere soils, bulk soil, roots and leaves of Brassica pekinensis Rupr.. Rhizosphere soils were collected after 8 weeks of plant growth by first removing the bulk soil from the root system and then by mechanical move off the rhizosphere soil that adhered to the root surface with soft brush. Soil and plant materials were simultaneously extracted with the mixture of methanol and sulfuric acid (100:7, v/v). Seven organic acids, oxalic, malonic, fumaric, succinic, maleic, L-malic and citric acid were identified and quantified by GC equipped with FID. Oxalic, L-malic, and citric acids were found in both the bulk and rhizosphere soils, while most LOAs were not detected in the control treatment. On the contrary, except maleic acid, all other organic acids were detected in the leaves and roots of cabbages treated with nitrate deposition.

Clinical and Pathological Factors Related to the Prognosis of Chinese Patients with Stage Ⅰb To Ⅱb Cervical Cancer

Xie, Xiu-Zhen,Song, Kun,Cui, Baoxia,Jiang, Jie,Zhang, You-Zhong,Wang, Bo,Yang, Xing-Sheng,Kong, Bei-Hua Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.11

Objective: The aim of this retrospective study is to analyze the clinical and pathological factors related to the prognosis of Chinese patients with stage Ib to IIb cervical cancer. Methods and Results: 13 clinical pathological factors in 255 patients with stage Ib to IIb cervical cancer undergoing radical hysterectomy and systematic lymphadenectomy were analyzed to screen for factors related to prognosis. The cumulative 5-year survival of the 255 patients was 75.7%. The result of the univariate analysis suggested that clinical stage, cell differentiation, depth of cervical stromal invasion, parametrial tissue involvement, and lymph node metastasis were prognostic factors for patients with stage Ib to IIb cervical cancer (P<0.05). Compared with cases with involvement of iliac nodes, obturator nodes, or inguinal lymph nodes, cases with metastasis to the common iliac lymph nodes had a poorer prognosis (P<0.05). Cases with involvement of four or more lymph nodes had a poorer prognosis than those with involvement of three or fewer lymph nodes (P<0.05). Using multivariate Cox proportional hazards model regression analysis, non-squamous histological type, poor differentiation, parametrial tissue involvement, and outer 1/3 stromal invasion were found to be independently related to patients poor prognosis (P<0.05). Conclusion: Non-squamous histological type, poor cell differentiation, parametrial tissue involvement, and outer 1/3 stromal invasion are the independent poor prognostic factors for patients with stage Ib to IIb cervical cancer.

Emodin-Provoked Oxidative Stress Induces Apoptosis in Human Colon Cancer HCT116 Cells through a p53-Mitochondrial Apoptotic Pathway

Xie, Mei-Juan,Ma, Yi-Hua,Miao, Lin,Wang, Yan,Wang, Hai-Zhen,Xing, Ying-Ying,Xi, Tao,Lu, Yuan-Yuan Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.13

Emodin, a natural anthraquinone isolated from the traditional Chinese medicine Radix rhizoma Rhei, can induce apoptosis in many kinds of cancer cells. This study demonstrated that emodin induces apoptosis in human colon cancer HCT116 cells by provoking oxidative stress, which subsequently triggers a p53-mitochondrial apoptotic pathway. Emodin induced mitochondrial transmembrane potential loss, increase in Bax and decrease in Bcl-2 expression and mitochondrial translocation and release of cytochrome c to cytosol in HCT116 cells. In response to emodin-treatment, ROS increased rapidly, and subsequently p53 was overexpressed. Pretreatment with the antioxidant NAC diminished apoptosis and p53 overexpression induced by emodin. Transfecting p53 siRNA also attenuated apoptosis induced by emodin, Bax expression and mitochondrial translocation being reduced compared to treatment with emodin alone. Taken together, these results indicate that ROS is a trigger of emodin-induced apoptosis in HCT116 cells, and p53 expression increases under oxidative stress, leading to Bax-mediated mitochondrial apoptosis.

The Prognostic Significance of Notch1 and Fatty Acid Binding Protein 7 (FABP7) Expression in Resected Tracheobronchial Adenoid Cystic Carcinoma: A Multicenter Retrospective Study

Mian Xie,Xiaojun Wu,Jinjun Zhang,Chaosheng He,Shenhai Wei,Junyao Huang,Xinge Fu,Yingying Gu 대한암학회 2018 Cancer Research and Treatment Vol.50 No.4

Purpose Adenoid cystic carcinoma (ACC) of the trachea and bronchus is a rare tumor. Although MYBNFIB oncogene fusion and Notch1 mutation have been identified in ACC, little is known about the expression and clinical significance of Notch1 and its target gene fatty acid binding protein 7 (FABP7) in tracheobronchial ACC. Materials and Methods Primary tracheobronchial ACC that were resected between 1998 and 2014 were identified through the pathology and oncology database from five thoracic oncology centers in China. A tissue array was constructed from the patients’ samples and the expressions of Notch1 and FABP7 were evaluated by immunohistochemistry. The association between the expression of both markers and survival was determined. Results Overexpression of Notch1 and FABP7, detected in 37.8% and 38.3% of 368 patients with tracheobronchial ACC, respectively, was an independent prognostic indicator for recurrencefree survival (RFS) by multivariable Cox proportional hazard model (p=0.032 and p=0.048, respectively). Overexpression of Notch1, but not of FABP7, predicted overall survival (OS) (p=0.018). When categorized into four groups according to coexpression of Notch1 and FABP7, patients with overexpression of both Notch1 and FABP7 belonged to the group with the shortest RFS and OS (p=0.01 and p=0.048, respectively). Conclusion Expression of Notch1 and FABP7, and coexpression of Notch1 and FABP7, is strongly associated with poor survival in resected tracheobronchial ACC. These data are consistent with the hypothesis that poor differentiation of tracheobronchial ACC correlates with the activation of Notch signaling.