Rolling Ball Viscometer에 依한 乳牛의 準臨床型 乳房炎의 感染率에 關한 調査硏究

朴玉潤,曺熙澤 진주산업대학교 1984 論文集 Vol.22 No.-

This study was conducted to find out the infection rate of subclinical type and suspected positive of mastitis of dairy cows using Rolling Ball viscometer. The tested fore milk samples were collected from 1604 teats of 404 Holstein which their somatic cell number had more than 250,000 per mililiter, and these cows were selected from 241 farms located in Kyung­nam province for months from March 1984 to October 1984. The comatic cell number were measured by the viscometer, and the relation between the number of somatic cells of the sample and the cause factors of mastitis were examed, and the results obtained were as follows. 1. The sample which its somatic cell number has less than 250,000 denoted as negative infection was 26.9%, between 250,000 and 490,000 denoted as suspected positive infection was 28.6% and more than 500,000 denoted as positive infection was 24.5%. 2. In the case of the infection rate, 53.5% was infected among 404 cows and 26.0% was infected among 1606 teats. 3. In the test of suspected positive infection and subclinical type according to farm scale, the small scale farm(raising 1 to 10 cows per farm) has 54.7%, the medium scale farm(11 to 20 cows) has 43.5%, the large scale farm(21 to 30 cows) has 50%., and more than 31 cows per farm showed negative infection rate. The less scale farm showed the hiher the % of suspected positive infection. 4. In the case of suspected positive and subclinical type rate according to milking methods, it was 53.8% by milker and 28.6% by hand. 5. In the case of suspected positive and subclinical type rate according to disinfection by soaking the treats into the anticeptic solution after milking, the disinfected cows have 40.5% and nondisinfected cows have 64.8%. 6. In the case of suspected positive and subclinical type rate accoring to the type of administraters, It was 48.1% by ranchman and 89.7% by herd man. 7. In the case of suspected positive and subclinical type rate according to the number of years for raising the cows(personel experiences), It was 44.0% in the case of one year's experience, 45.1% in 2 to 3 years, 58.6% in 4 to 5 years and 69.1% in the case of more than 6 years of experience As the feeding experience increased the infection rate of subclinical type of mastitis was decreased.

소의 創傷性 第二胃炎 發生例에 關한 考察 : 一般 臨床症狀 및 炳理解剖學的 所見에 關하여 an observation of general clinical aspects and pathological anatomy

朴玉潤,李乙熙 진주산업대학교 1977 論文集 Vol.15 No.-

晋州農專에서 飼養中인 holstein種 (♀ 4才, 2産牛)이 1976年 4月 21日 分娩後 3日만에 急激한 食慾減退 乳量減少 症狀이 나타남으로 治療하였으나 豫後不良하여 切迫屠殺後에 實驗用으로 病理解剖를 한 結果를 要約하면 다음과 같다. 1. 第二胃內에서 金屬性異物 7種 27個를 發見하였다. 2. 그中 主原因은 尖銳한 鐵系(15番線 길이 9㎝)가 第二胃 粘膜을 貫通進行하여 脾頭表面에 達하여 있었다. 3. 脾臟實質은 化膿性 또는 壤死性病變과 肝實質의 腫脹 및 小葉의 化膿性病變으로 黃色部位가 限界鮮明하였다. 4. 腹腔內에는 混濁한 渗出液이 貯溜한 것으로 보아 汎發性 腹膜炎이 倂發한 것으로 認定되었다. A holstein cow that was 4 years old and 2nd delivery was suffered from the sudden anorexia and the decrease of the amount of milk at the feeding stable of Jinju Agir. & Forestry Junior Technical College after 3 days of parturition, on April 21, 1976. It was cured, but the condition of this disease was very bad prognosis. Therefore it had been killed to investigate the symptom of pathological anatomy. The results obtained were as follows. 1. It was found 27 piece and 7 kinds of material foreign bodies in the reticulum. 2. The sharp steel wire(No. 14 wire, Length 9 ㎝) of these material foreign bodies was perforated the reticulm and reached to the surface of the spleen. 3. The spleen tissue had the degeneration of the supperation and the necrosis, and the part of the liver tissue was changed to the yellow portion cleary bybecause of the swelling of liver tissue and the supperative change. 4. It had been found that the diffuse peritonitis was complicated by the accumulation of cludy exudatin in the abdoman.

닭의 乾燥 筋胃粘膜 粉末 投與가 家兎의 發育效果에 미치는 實驗的 硏究

朴玉潤,李乙熙 진주산업대학교 1979 論文集 Vol.17 No.-

This experiment was conducted to determine the effect of Fowl gizzard mucouse membrane dry powder treatment on growth of rabbits. 20 heads male and 20 heads female of New zealnd white were allotted for 4 treatments according to the levels of Fowl gizzard mucouse menbrane dry powder in their ration such as 0.2g, 0.4g and 0.6g per ㎏ of body weight, respectively. During the period of 60 days from October 15, 1979 to December 13, 1979 an experiment had been carried out at Jinju Agricultural and Forestry Junier Technical Collage to compare body weight gain, the number of erythrocytes and concentation of hemoglobin. The results obtained were summerized as follows: 1. The body wieght gain of male and female at 0.2g of level was superior to the other, and statistical difference was found.(p<0.05) 2. The dressed carcase percentage of male and female was 49.8∼50.5% and 47.1∼50.9%. 3. The viscera fat weight ratio of male and female was 0.21∼1.75% and 0.64∼1.02%. 4. The heart weight ratio of male and female was 0.33% at 0.2g level, but other plots was 0.17∼0.24%. 5. The liver weight ratio of male and female was 2.19∼2.99% and 2.77∼3.50%. 6. The kidney weight ratio of female was 0.3% at 0.4g level, But other lots was 4.48∼0.49 and female was 0.41∼0.42 at control and 0.2g levels, and 0.48∼0.49% at 0.4g level and 0.6g level, respectively. 7. The spleen weight ratio of male and female was 0.03∼0.04% and 0.04∼0.06%. 8. The number of erythrocytes and concentration of hemoglobin increased at treatment groups compare with control.

반복치료로 호전된 호산구성 폐렴 유사 폐흡충증 1예

박세진,김희규,김봉준,이천우,옥철호,정만홍 고신대학교 의과대학 2010 고신대학교 의과대학 학술지 Vol.25 No.2

우리나라에서 인기 있는 게장등의 섭취로2) 성인뿐만 아니라 소아에서도 지속적으로 보고되고 있는 폐흡충증은 다양한 임상양상을 보일 수 있다. 저자들은 방사선 소견상 만성 호산구성 폐렴과 유사하였고, 반복적인 치료로 호전된 폐흡충증 1예를 경험하였기에 보고하는 바이다. Paragonimiasis mostly occurs by ingestion of raw or undercooked freshwater crabs or crayfish. Recently, re-emergence of paragonimiasis is reported because of ingestion of raw food such as freshwater fish and Gejang (marinated raw crabs). As the radiological features as well as the laboratory findings are similar to those of chronic eosinophilic pneumonia, the diagnosis of pulmonary paragonimiasis is often difficult and delayed. A 43 year-old female was visited our hospital for migrating and new developing consolidative lung lesions and peripheral blood eosinophilia. The eosinophil profile of leukocyte was 32% (absolute count 2,690 /mm3). Histologic finding was organizing pneumonia pattern with severe infiltration of eosinophils. Parasite specific antibody IgG forParagonimus westermani was positive (titer:0.61, normal range<0.20). After treatment with praziquantel (75mg/Kg once a day for 2days), the chest x-ray was clearly resolved. Follow-up study showed right pleural effusion, newly developed focal infiltration, and several nodules. After retreatment, we couldn't find any recurrent evidence.

家兎의 血液像에 關한 硏究 : 第Ⅱ報 뉴질랜드 화이트 雌兎의 血液像 Ⅱ. The normal blood count of female New Zealand White

李乙熙,朴玉潤 진주산업대학교 1979 論文集 Vol.17 No.-

This experiment was carrid out determine the normal blood picture of rabbits, which were raised at the farm in jinju Agricultural and Forestry Junier Technical Collage. The experimental rabbits was 4-heads of female New Zealand White. The results obtained were sumarized as fallows. 1. The number of erythrocytes was 4.607×10 exp (6)/㎣. 2. Total leucocyte enumeration was 13.862×10 exp (6)/㎣. 3. Concentration of hemoglobin was 66.25 percent. 4. The value of hematocrit was 36.5 percent. 5. Differential cell count was Neutrophle 45.75%, Lymphocyte 48.0%, Monocyte 2.5%, Eosinophile 2% and Basophile 1.75%.

Maillard 反應에 關한 硏究 : Ⅴ. 反應溫度 및 時間이 skim milk의 Maillard reaction에 미치는 영향 Ⅴ. Effects of reaction temperature and time on the Maillard reaction by heating skim milk

李乙熙,朴玉潤,徐珠銖,高鏡畢 진주산업대학교 농업기술연구소 1993 農業技術硏究所報 Vol.6 No.-

The color intersities of melanoidins and the contents of HMF in skim milk by heat treatment. The contents of HMF in skim milk were detected in all heat-treated skim milk by colormetrical method and HPLC method. The color intensities of melanoidins showed significant dependence on reaction temperature and time. The contents of HMF in skim milk were detected in all heat treated skim milk by colormetrical method. While they were not detected by HPLC method when skim milk was heated at the temperature 70℃ for 30, 50 and 70 minutes. It showed significant dependence of reaction temperature and time.

Rat H-Y 抗體가 생쥐 수정란의 발달단계에 따른 체외배양에 미치는 영향

鄭場龍,朴喜成,朴玉潤 진주산업대학교 농업기술연구소 1993 農業技術硏究所報 Vol.6 No.-

本 硏究는 免疫學的 방법에 의하여 性을 調節할 수 있는 방법을 개발하고자 近郊系統의 Wistar흰쥐의 수컷비장을 摘出하여 均質化시킨 다음 상충액을 취하여 同種의 암컷 腹膣內에 接種함으로서 H-Y抗原에 대한 H-Y 抗 血淸을 제조하였으며, 제조된 H-Y抗 血淸과 함유한 培養液에 ICR系統의 생쥐로부터 각 발달단계별로 채란한 수정란을 NaHCO3-BMOC-3 배양액에 H-Y항 혈청과 보체를 첨가하여 CO_2 incubator에서 24∼30시간 배양을 실시하였다. 본 연구에서 얻은 결과는 다음과 같다. H-Y 抗體의 形成은 rat 10마리중 8마리에서 抗體가 형성되어 80%의 形成率을 보였으며, 427개의 수정란을 H-Y 抗體를 處理하여 이중 182개(43%)가 파괴 되었다. H-Y 抗血淸 및 補體의 存在下에서 培養된 2-, 4-, 8-, 16-세포기, 상실배 및 胞胚期 수정란의 파괴율은 각각 0.0, 42.9, 54.1, 47.0, 48.1 및 47.5%로서 2-세포기와 4-세포기 以上間에는 유의적 (P<0.05)인 差異가 있었으나, 4-세포기 이상과 胞胚期 受精卵間에는 H-Y 항체가 미치는 영향은 유의적(P<0.05)인 차이가 없었다. This experiment was carried out to develop a new technique of identifying XX or XY-bearing mouse embryos by immunological method. H-Y antiserum prepared in inbred Wistar female rats by repeated immunization with spleen cells from males of the same strain. The reactivity of H-Y antibody was confirmed by culturing mouse embryos in the medium containing H-Y antiserum and complement obtained from the guinea pig. The optimal condition for the activity of H-Y antibody was also investigated by culturing embryos under the concentration or affected H-Y antibody and in vitro culture rate. The bilological test with the 8- or 16-cell stge embryos showed H-Y antibody was formed in all female rats immunized with spleen cell, but it was formed only in 80% female rats immunized with the antigen. When the embryos were in vitro cultured in the medium of H-Y antiserum and complement the lysis rate of 2-, 4-, 8-, 16-, morula and blastocyst was 0.0, 42.9, 54.1, 47.0, and 47.5% respectively, but significantly(P<0.05) low than that of 2-cell stage.

진행성 폐 종양 환자에서 종양 내 OK-432 주입술의 효과

정수현,김성빈,박진희,탁희상,옥철호,장태원,정만홍,천봉권 고신대학교 의과대학 2009 고신대학교 의과대학 학술지 Vol.24 No.2

Background: Intratumoral injection of OK-432 produced significant antitumor effects. There are reports that OK-432 was injected directly into tumor tissue on gastrointestinal tracts and HCC tissue, producing decrease in serum alpha-fetoprotein level. We adopted this technique for treating locally advanced lung cancer. The object of this study is to evaluate the local therapeutic efficacy, side effects of injection for treating symptomatic mass. Methods: Twenty lung cancer patients (13 males and 7 females) underwent sonography guided OK-432 injection. We analyzed relationships between response of OK-432 and response of skin test, histology and age. Pain that patients feel was evaluated by VAS (Visual Analog scale). Results: A significant decrease of tumor size was observed. The mean pre-injection diameter of the lesions was 54.7±11.3mm, PR rate were 15.0% (3/20) and minimal change (50%<tumor size decreased.) patients were 35.0% (7/20). The VAS score before injecting OK-432 into the lesion was 5±3, this was decreased to 2.5±1.5 (p=0.04). Object response was significantly correlated with skin response, adenocarcinoma, and age. Conclusion: A significant decrease of tumor size and pain was observed. So OK-432 is a valuable treatment option for patients with symptomatic lesion from advanced lung cancer who are not amenable to further therapy.

임상간호사 역할정립에 관한 연구

지성애,이은희,조경숙,서문자,강현숙,임난영,김주현,손행미,권성복,김동옥,박영숙,손영희,한혜자,이여진,성영희,박광옥,박정원,이계숙 병원간호사회 2004 임상간호연구 Vol.9 No.2

Purpose: To identify the clinical nurses' role in hospitals in Korea to provide the basic data needed for the establishment of the policy of nursing practice. Method: Four stages of multi-dimensional survey was done inductively during 2002,7 to 2003, 7. At the first, nurse role activities were sorted with the rigorous review of the related literatures and documents and simultaneously, the data were collected by Delphi methods from professional nurses and interview with patients and their families. Secondly, research seminars were done many times to validate the contents of nurses role activities and its components with analysing the first data and classified them into nurse role and it's activities. Thirdly, massive nationwide survey on the frequency and the perceived importance of the nurse role activities from the nurses, physicians, patients and their families using the questionnaire developed by the research team. At fourth stage, research seminars were held several times to analyse the data thoughtfully. Total 1,133 composing of 652 nurses, 206 physicians and 275 patients in 40 hospitals sized over 500 beds nationwide. And there was a group of panelist composing of 17 experts. Result: Nurses' Roles and Nurses' Role Activities were identified as follows : At first step, 868 Nurses' Role Activities from literature reviews, and 981 from Nurses' Role Activities with Delphi method were sorted. At second step, 30 nurses roles and 772 nurses' role activities were sorted from the analysis of the data from the first step. Finally 40 nurses roles and 770 nurses' role activities were identified through the validation process with the research team seminar. The perceived frequency on nurses' role activities of clinical nurses was significantly different upon their ages, experiences, working places, and positions. The higher the educational level, the more perceived importantly their role activities significantly. The average score of the perceived frequency was 3.17(max. : 5) and the average scores of the perceived importance of nurse' role activities were different among nurses(4.10), doctors(3.55) and patients(3.58). Conclusion: Since these results were obtained from multi-dimensional approach nationwide, and the intensive validation process of contents were scrutinized thoughtfully, this data could be used as basic information to establish the nurse policies regarding to nurse job description and planning the nurse's man power.

Atracurium 에 의한 중중근무력증 환자의 근육이완

박광원,김원옥,남순호,윤경봉,사희순 대한마취과학회 1987 Korean Journal of Anesthesiology Vol.20 No.1

Generally, myasthenic patients are believed to have enhanced sensitivity with variety to the nondepolarizing neuromuscular blockade, even though some authors do not agree with that. Recent1y, the use of the new intermediate-acting nondepolarizing relaxant atracurium has been reported in patient with myasthenia gravis. The unique mode of elimination of atra-curium, which undergoes spontaneous degradation at physiologic body temperature and pH. may offer an advantage over the previously available Bong-acting muscle relaxants. We describe a case report of the anesthetic management of mysthenic patient using atracurium because of its relatilvely rapid rate of recovery. Reduced dosage of atracurium appeared to be a reasonable choice for myasthenic patients requring surgical relaxation when clinically indicated. However, continuous monitoring of neuromuscular function is of course mandatory for the proper and safe use of atracurium.