SD Rats를 이용 1-hexene의 흡입독성 연구

김현영,임철홍,정용현,이권섭,이성배,이준연,한정희,전윤석,이용묵 한국환경독성학회 2001 환경독성보건학회지 Vol.16 No.4

The purpose of this study was to investigate the acute (4 hours) and repeated-dose (6 hours a day, 5 days a week, 4 weeks) toxic effects of I -hexene on Sprague- Dawley (SD) rats which were treated by inhalation. The results were as follows; I. The median lethal concentration (LC_(50)) was estimated 52,694 ppm (confidence limit 95%; 49,494~55,447 ppm) in acute inhalation. Abnormal clinical signs related to the l-Hexene were not observed with the acute inhalation dose. Gross findings of necropsy revealed on evidence of specific toxicity related to the 1-hexene, II. By repeated inhalation exposure the body weight of male were more or less reduced by the dose of 2,500 ppm and 5,000 ppm compared with control group. However there were no significant variation hematology and blood biochemistry for the exposed rats compared with the control rats. Abnormal clinical signs and gross findings of necropsy related to the 1-hexene were not shown. In conclusion when we exposed I-hexene to SD rats for 4 weeks, 5 days per week, 6 hours per day, the Lowest observed effect level (LOEL) was over 2,500 ppm and Non observed effect level (NOEL) was below 500 ppm.

크롬(Ⅵ)의 체내 흡수와 소실속도에 관한 연구

김현영,이성배,임철홍,이권섭,정용현,이종성,한정희,전윤석,황호순,이용묵 한국산업위생학회 2003 한국산업보건학회지 Vol.13 No.1

The CrO3 mostly used in plating. metal surface disposal, leather, cosmetic manufacturing, as an experiment material by repeatedly inhaling and exposure the male S.D. rats at a 0.00, 0.2., 0.50, 1.25 mg/㎡ concentration(particle size: 0.5-0.5 aerosol)6hours a day, 5day a week in 13weeks comparing with 2weeks, 8weeks of recovery group about the noxiousness of the experiment animal and the reduce scale of the CrO3 in the internal organ especially in blook and respiratory organ with the period of convalescent and clearance. The experiment results which we received are as follows. 1. In blood the RBC, HGB and HCT experiment, rats with 0.20, 0.50 mg/㎡ concentration showed that there were some decreases but not dependent. The kidneys absolute weight compared with control group was reduced intentionally(p〈0.05) and the lungs absolute weight compared with control group showed intentional increase(p〉0.05). 2. After the exposure of the experiment material, the whole blook, l\blood plasma and red blood cell in blood by (x): the period of convalescent, per (y); the decreasing of Cr concentration, was y=66.51 e -0.057x, y=67.2 e-0.101x, y=70.01 e-0.030 in 0.50 mg/㎡ exposure concentration by calculating the clearance coefficient of correlation, and the half life (day)was estimated 12.0, 6086, 23.0 each. 3, After the exposure of the experiment material, the experiment animals lung, liver and kidneys by(x); the period of convalescent, per (y); the decreasing of Cr conentration, was y=1808 e-0.00493x, y=12.02e-0.0297x, y=67.61 e-0.0292x in 0.50mg/㎡ exposure concentration by calculating the clearance coefficient of correlation, and the half life(day)was estimated 140.6, 23.3, 23.7, each, and including lung, liver with all of the experiment internal organs, the Cr clearance decreased as the exposure concentration increased.

KF114와 KB108 원료가공업의 연기증 Nicotine 및 Tar 함량의 변화

이철희,임흥빈,신주식,석영선 충북대학교 연초연구소 2004 煙草硏究 Vol.19 No.-

궐련담배 연기 중 Tar와 Nicotine 함량은 대부분의 국가에서 담배 포갑지에 표시하도록 규정하고 있으며 우리나라에서도 2003년부터 시행하고 있다. 그리하여 궐련담배 제품의 설정목표에 따라 엽배합의 방안을 강구하고자 우리나라에서 생산하고 있는 황색종과 버어리종의 주 품종인 KF114와 KB108의 원료 가공엽을 김천원료공장과 남원료공장에서 착엽위치 및 등급별로 채취하여 연기 중 Nicotine, Tar 및 CO 함량을 조사하였으며, 그 결과를 요약하면 다음과 같다. 1. 원료엽 중 니코틴 함량은 황색종 KF114에 비하여 버어리종 KB108이 높고, 본엽과 상엽에서는 등급이 낮을수록 함량이 높고, 중엽과 하엽에서는 등급이 낮을수록 함량이 낮았다. 2. 황색종 KF114는 궐련담배 1개비 당 중량이 본엽, 중엽, 상엽, 하엽 순으로 무거웠고, 엽위별 등급간에는 등급이 높을수록 무거웠다. 연소시간과 흡연회수는 본엽, 상엽, 중엽, 하엽 순으로 길고 많았다. 3. 버어리종 KB108은 궐련담배 1개비 당 중량이 상엽, 본엽, 중엽, 하엽 순으로 무거웠고, 엽위별 등급간에는 등급이 높을수록 무거웠다. 연소시간은 상엽, 본엽, 중엽, 하엽 순으로 길었으며, 중엽과 하엽에서는 등급이 높을수록 본엽과 상엽에서는 등급이 낮을수록 길었다.4. 황색종 KF114 원료 가공엽의 연기 중 니코틴과 타르 함량은 본엽에서는 등급이 낮을수록 높고, 중엽과 하엽에서는 등급이 높을수록 높은 값을 나타냈다. CO 함량은 본엽, 중엽, 상엽, 하엽순으로 많았고, 등급간 차이는 니코틴과 타르 함량에 대한 등급간 차이보다 적었다. 5. 버어리종 KB108 원료 가공엽의 연기 중 니코틴과 타르 함량은 상엽과 본엽에서는 등급이 낮을수록 높고, 중엽과 하엽에서는 등급이 높을수록 높은 값을 나타냈다. CO의 함량은 상엽, 본엽, 중엽, 하엽 순으로 높았고, 엽위 별 등급간에 차이가 없었다. 6. 잎담배 종류 및 가공엽의 등급에 따라 nicotine/tar 및 Co/tar 비율에 차이가 있는 것을 알 수 있으며, 엽위가 낮을수록 비율도 감소하였다. 7. 버어리종 KB108는 흡연회수, 니코틴, 타르및 CO가 각각 정의 상관관계가 인정되었으나, 황색종 KF114에서는 CO와 니코틴, CO와 타르 간에는 상관관계가 없었다. In most countries, nicotine and tar contents of cigarette smoke should be represented on the cigarette pack by law. It has been carrying out in Korea from 2003. In order to control those contents, It was tested the contents of tar, nicotine, carbon monoxide (CO) of smoke components and puff number for blending two major varieties produced in Korea, KF114, a flue-cured, and KB108, a burley. The processed leaf tobacco were taken from Kim-cheon and Ock-cheon leaf tobacco processing factory. The results were summarized as followed ; 1. Nicotine contents of processed leaf tobacco were higher in KB108, a burley, than in KF114, a flue-cured. Nicotine contents of leaf and tips were higher in low-grade leaves than in high-grade leaves, but those of cutters and lugs were lower in low-grade leaves than in high-grade leaves. 2. The weight per cigarette of KF114 was heavier in the order of leaf, cutters, tips and lugs, and was heavier in high-grade leaves than in low-grade leaves. Combustion time was longer and puff number was more in the order of leaf, tips, cutters and lugs. 3. The weight per cigarette of KB108 was heavier in the order of tips, leaf, cutters and lugs, and was heavier in high-grade leaves than in low-grade leaves. Combustion time was longer in the order of tips, leaf, cutters and lugs. The time of cutters and lugs was longer in high-grade leaves than in low-grade leaves, but those of leaf and tips was longer in low-grade leaves than in high-grade leaves. 4. Nicotine and tar contents of the smoke from the processed leaf tobacco of KF114 were higher in low-grade leaf than in high-grade leaf and cutters and lugs were higher in high-grade than in low-grade. CO contents were higher in the order of leaf, cutters, tips and lugs. The difference of CO contents between different grades was lower than that of nicotine and tar contents. 5. In nicotine and tar contents of the smoke from the processed leaf tobacco of KB108, leaf and tips were higher in low-grade than in high-grade and cutters and lugs were higher in high-grade than in low-grade. CO contents were higher in the order of tips, leaf, cutters and lugs. There was no significant difference of CO contents between different grades of the stalk position. 6. Nicotine/Tar and CO/Tar ratios showed significant difference according to tobacco variety and grade of processed leaf tobacco. The ratios were reduced in lower stalk position. 7. There were positive correlations between puff number, nicotine, tar and CO contents in KB108, but there were no correlations between CO and nicotine, or CO and tar in KF114.

참깨 育種을 위한 量的形質의 遺傳에 關한 硏究 : 참깨의 遺傳力 및 諸形質間의 相關에 關하여 Estimation of Heritability and Interrelationships of Some Characters in Sesame

李喆浩,文永培 진주산업대학교 1985 論文集 Vol.23 No.-

참깨의 育種計劃을 위해 참깨 82品種의 集團에서 8가지 形質에 대한 遺傳力 및 遺傳相關을 推定하므로서 量的形質의 效率的選拔과 形質間의 遺傳的 相互關係에 대한 有用한 情報를 얻기 위하여 本硏究를 修行하였으며 그 結果를 要約하면 다음과 같다. 1. 8個形質에서 開花日數, 生育日數 및 着삭部位長의 遺傳이 가장 높고 莖直徑과 節間長의 遺傳力은 가장 낮았다. 2. 가장 높은 遺傳相關을 보인 形質들은 이삭부위장과 草長間에, 生育日數와 草長間等에서 認定되었으며 遺傳相關의 값이 表現型相關 값보다 一般的으로 높았다. 3. 이삭부위장, 莖直徑 및 開花期間은 收量과 높은 正의 相關을 보였고 開花日數만은 높은 負의 相關을 보였으며 生育日數와 草長은 數量과 가장 낮은 遺傳相關을 보였다. 4. 遺傳力과 遺傳相關係數를 同時에 考慮할적에 開花日數와 이삭부위장이 收量의 主要構成形質로 보이며 增收를 위한 效率的인 選拔은 早期에 開花日에 到達하며 이삭부위장이 긴 系統을 選拔하므로서 可能하리라고 생각된다. This studies were worked out to obtain useful information on the effective selection and the genetic relationship of quantitative characters for the planning of sesame breeding by estimating the heritabilities and the genotypic correlations among 8 agronomic characters in the population of 82 sesame varieties. The results obtained are summarized as follows; 1. Heritability of days to flowering, days to maturity and length of stem with capsule were the highest, those of stem diameter and internode length were the lowest in 8 quantitative characters.(Table 3). 2. The highest positive correlations were shown between length of stem with capsule and plant height, and between days to maturity and stem diameter etc, genotypic correlations were slightly higher than the corresponding phenotypic correlations.(Table 5). 3. Length of stem with capsule, stem diamter and durations of flowering gave positive and highly significant correlation, but days to flowering gave negative correlations as the same level, days to maturity and plant height showed non-significant correlations with yield and with one another at genotypic correlation coefficients. (Table 5). 4. Taking the values of geritability and genotypic correlation into consideration, days to flowering and length of stem with capsule are important yield-contributing characters, these results suggest that effective selection for seed yield can be made by selection for lines possessing the characters to reach early flowering time and take long stem with capsule.

복숭아 光合成能力의 時基別 變動과 品種間 差異

李喆浩,文永培,金正洙 진주산업대학교 농업기술연구소 1991 農業技術硏究所報 Vol.4 No.-

복숭아 矮性台木 利用에 의한 樹形의 矮性化는 近年의 일이며 低樹高栽培의 實用化 趨勢에 副應하여 矮性台木으로서 有望視되는 Prunus Persica(壽星桃)로서 接首品種은 8年生된 白鳳과 白桃를 供試하여 6月15日, 7月15日, 8月15日과 9月15日에 걸쳐서 地上 3.5m, 2m, 50cm높이에 着生된 主枝의 側枝新梢를 採取하여 잎의 光合成 能力을 分析한 結果는 다음과 같다. 1. 白鳳의 部位別 新梢의 光合成 速度는 上部>中部>下部의 順으로 빠르게 進行되었고 照度가 增加할수록 光合成 速度도 빨라지는 傾向이였다. 2. 白桃의 部位別 新梢의 光合成 速度는 6月과 9月은 上部가, 7月은 下部가, 8月은 中間 部位가 각각 높았다. 3. 복숭아의 光合成 能力은 6月부터 8月까지는 점점 增加되다가 9月부터 떨어지며, 7월과 8월은 白鳳이, 8月과 9月은 白桃가 光合成 能力이 더 큰 것으로 나타났다. There is a growing tendency of dwarfing fruit trees. So in this study the 8-year-old peach varieties, "Baekbong" and "Baekdo", engrafted on Prunus persica, which is promising for dwarf stock, were tried as experimental materials. The shoot sampling was done on June 15, July 15, August 15, and September 15. And the parts or smpling were 3.5m, 2m and 50cm above earth surface, respectively. The shoots were sampled from the outer parts of main branches, and the photosynthetic ability of the shoot leaves was analyzed as follows: 1. The photosynthetic rate of Backbong's shoots was highest at the top main branches; second highest at the middle ; and lowest at the lower main branches. As the light intensity increased, the photosynthetic rate became higher. 2. The Photosynthetic rate was highest at the top main branches in June and September ; in July, it was highest at the lower part ; and in August, it was highest at the middle part. 3. The photosynthetic ability of peaches increased gradually from June till August, but it decreased after September. In July and August, the photosynthetic ability of Baekbong was higher ; in August and September, that of Baekdo was higher than that of Baekbong.

S.D. Rats를 이용 1, 1-Dichloro-1-fluoroethane의 아민성 흡입독성 연구

김현영,이성배,임철홍,김철우,점용현,한정희,전윤석,최수영,강대봉,이용묵 한국환경독성학회 2002 환경독성보건학회지 Vol.17 No.1

There were no specific effects for test materials on Sprague-Dawley (S.D.) rats in clinical symptoms, amounts of food intakes, weight changes, laboratory findings, and pathology after whole body l, l-Dichloro-1 -fluoroethane (used as coolant, metal cleaner and solvents) exposure(0, 1,500, 3,000, and 6,000 ppm) for 13 weeks (6 hour/day, 5 days/week). However, the loss of capillary vessels in eyeball (pupil) was observed in a female rat among 6,000 ppm group. Though there was a tendency for MCHC (Mean Corpuscular Hemoglobin Concentration) in rat to be decreased (p<0.05), it was not regarded as abnormal because the values were within normal limits. In asthma-stimulation related evaluations, there was also a tendency for inflammatory cell counts in bronchoalveolar lavages to be increased. But it had no statistical significance, and also no dependency on sex and the exposed concentration. Based on this result, the non observed effect level (NOEL) induced by 1, 1-Dichloro-l -fluoroethene inhalation was evaluated in groups with 3,000 ppm below (S .D. Rats, 13 weeks). Finally, it was concluded that the short term exposal of 1, 1-Dichloro-l-fluoroethane is not considered as a asthma stimulant by inhalation despite of some study limitations such as test animals use and short-term exposure .

갈륨합금과 아말감의 전기화학적 부식거동 비교

고영무,최한철,강성남,강희영,이승윤 대한치과기재학회 1998 대한치과재료학회지 Vol.25 No.3

A gallium based alloy(GA) that was developed as a substitute for dental amalgam was investigated for electrochemical corrosion behavior in 4 kinds of electrolytes(1% lactic acid, 0.05% HCI, Modified Fusayama's artificial saliva, and 0.9% NaCl). The related corroded microstructure were examined and microanalyses were conducted using ICPES. Polarization tests were conducted by scanning from -1,500㎷ to 1,000㎷(vs.SCE) at 75㎷/min. The obtained results were as follows: 1. GA showed wide passivation area next to SYB in artificial saliva, suggesting good stability. 2. The amounts of Sn, Cu released from GA were similiar to those of CAV, and decreased in the order of KAT, SYB. 3. All of specimens were observed pits at the area of pores in electrolytes containing chloride ions, and forming much corrosion products in 1% lactic acid and artificial saliva after corrosion test. 4. From the surface analyses of XRD, GA showed much corosion products containing gallium at the surface after corrosion test. In conclusion, the corrosion resistance of GA was lower than that of SYB and similiar to that of CAV and KAT.

손짚고 뒤돌기의 動作分析

申榮吉,李基哲 慶北大學校 師範大學 體育學硏究會 1986 體育學會誌 Vol.14 No.-

The purpose of this paper is presenting helpful materials for direction and advancing skills by analysing motions of back handspring of the gymnasts who represent the province. After photographing back handspring motions of four college gymnasts who took part in the 64th National Athletic Meeting in the series of three-step running pace, round off, back handspring, tucked backward somersault with a movie camera (37 frame/sec), I could get the locus of motions. I compared the motions with ideal motions presented by specialist and get the following conclusion. 1. At the first landing, I found that they landed in a motion leaning forward by about 70°. I think this defect can be corrected through strong snap down practice in round off. 2. At the first landing, they erected their heads in 163°∼197°, and arms came down by 15° from the horizon when landing. I think this is a disadvantage to them in getting speed when the body is bent backward with arm-swing, and this defect can be corrected through the practice of landing with arms attached to ears. 3. At the phase from the first landing to the take-off, when bending the body backward, the head bent backward before swinging the arms. I think this is a disadvantage to them in getting sufficient speed when bending the body backward, and this defect can be corrected through the practice in which arms is attached to the arms intentionally in swinging arms backward. 4. At the phase from the first landing to the take-off, they swung their arms without relaxing the wrist. I think this is a disadvantage to them in bending the body speedily. 5. At the phase from take-off to hand touch, the legs were spread out during the inflight motion. I think this results from the gymnasts' habit of reducing the time which is used in tumbling by shorting their bodies, and this phenomenon happens among trained gymnasts unconsciously, reflectively and frequently. 6. In hand touch, the shoulder line was not cut, which is necessary so that the arms might be vertical against the land. I think this results from not getting sufficient speed in bending the body backward. 7. After the hand touch, the shoulder went forward and legs snaped down a little after the apex. I think this phenomenon happens because the hand off is delayed and the gymnast can't snap down the leg strong.

CdSe ; Cu 광전도 cell 제작

신영진,정태수,신현길,김택성,정철훈,이훈,신영신 경북대학교 센서기술연구소 1992 센서技術學術大會論文集 Vol.3 No.1

오·폐수 처리시설용 다공질 석재 개발

신영수,이윤수,연규석,김철영 강원대학교 부설 석재복합신소재 제품연구센터 1999 석재연 논문집 Vol.4 No.-

이 연구는 오·폐수에 함유된 유기물을 제거하기 위하여 일반 시멘트 콘크리트에 비해 우수한 역학적 성질을 갖는 폴리머를 이용한 현무암 다공질 석재를 개발하고, 이에 대한 물리. 역학적 특성 및 정화성능을 실험적으로 구명한 것이다. 그 결과 다공질 소재이나 강도가 높고 적당한 단위체적중량을 갖기 때문에 설치 후 안정성을 확보할 수 있고, 정화성능은 나일론 여재에 비해 떨어지지 않으므로, 현장 설치 및 시공방법에 대한 연구가 이루어질 경우 실용화가 가능할 것으로 판단된다. The objectives of this study were to develop porous media for sewage treatment facility using basalt and to explore the possibility of replacing wall structures of sewage treatment plants improve the efficiency of sewage treatment. It was shown that the porous media developed by using basalt was not as efficient as existing media. However, it is expected that the polymer porous media can be economically applied to existing waste treatment plants and help improve sewage treatment efficiency.