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과실이 크고 품질이 우수한 조생종 배 ‘금촌조생’ 육성
조광식(Kwang-Sik Cho1),손동수(Dong-Soo Son),강삼석(Sam-Seok Kang),김명수(Myung-Su Kim),홍경희(Kyung-Hui Hong),윤석규(Seok-Kyu Yun),조강희(Gang-Hui Cho),조현모(Hyeon-Mo Cho) 한국원예학회 2004 원예과학기술지 Vol.22 No.1
‘금촌조생’ 품종은 농촌진흥청 원예연구소 나주배연구소에서 1971년 ‘금촌추’의 품질을 개선하기 위해 당도가 높고 육질이 유연한 ‘단배’를 교배하여 1982년 1차 선발되었고, 1997년부터 5년 간 지역적응시험을 거쳐 2001년 최종 선발 및 품종보호출원 되었다. 수세는 비교적 강하고, 수자는 반개장성이다. 꽃가루가 풍부하며, 주요 재배품종과 교배친화성을 보인다. 또한 흑반병에 대하여 강한 포장저항성을 나타내었다. 숙기는 재배중인 ‘원황’ 품종보다 약 5일 정도 늦은 9월 3일로 추석에 출하하기 알맞은 품종이다. 과형은 ‘금촌추’와 같은 도원추형이고, 과피색은 황갈색이다. 과중은 593g이고, 당도는 13.2Bx이다. 육질은 유연하며 과즙이 풍부하고, 석세포가 없어 식미가 매우 우수하다. 그러나 과육선숙형 품종으로 원예적 수확기에도 과피에 녹색이 남지만, 완숙과가 되면 황갈색으로 착색된다. 상온저장 기간은 20일 정도로 다른 조생종에 비해 저장력은 좋은 편이다. ‘Geumchonjosaeng’ pear cultivar (Pyrus pyrifolia var. culta Nakai) originated from the cross between ‘Imamuraaki’ and ‘Danbae’ to improve the fruit quality of ‘Imamuraaki’ cultivar in 1971 at Naju Pear Research Institute of National Horticultural Research Institute (NHRI), Rural Development Administration (RDA). It was preliminarily selected in 1982 and named in 2001. The tree habit shows vigorous growth and upright spreading. It carries abundant pollen grains and shows cross compatibility with leading cultivars. Also it shows high resistance to black leaf spot (Alternaria kikuchiana) in the field condition. Optimum harvest time is around Sep. 3, which is 5 days later than that of ‘Wonwhang’, and it could satisfy consumer’s demand for high quality pear fruit in “Chuseok”. The obovate fruit shape resembles maternal parent, ‘Imamuraaki’ and skin color is green yellowish brown at normal harvesting time and gradually turned to yellowish brown at full ripennig state. Fruit weighs about 593 g, and the soluble solid content is 13.5 ˚Bx. The flesh is very soft and juicy and, rendering good eating quality. Shelf life is about 20 days under the ambient temperature, and it is a relatively long period as compare with other early season cultivars.
고속의 GaAs SRAM 을 위한 새로운 센스 앰프의 설계 연구
조희철,김선옥,이웅호,윤진섭,이진구 동국대학교 산업기술대학원 1993 산업기술논문집 Vol.1 No.-
A new sense amplifier is designed in order to realize high-speed GaAs SRAM's. The Schematics are similar to "a source coupled differential amplifier" execept that two analyzed using basic FET current equations. The transconductance of the new sense amplifier is approximately 3.5 times larger than that of the conventional sense amplifier. Output high voltage is reduced to about 0.64V, therefore, the time which reached V_(max) are reduced also. The simulation results show that the access time of 0.9ns and the power dissipation of 12.2mW are achieved in GaAs 16bit SRAM's.
α1,3-Gal Knock out Pigs Increases N-Glycolylneuraminic Acids
Jong-Yi Park,Mi-Ryung Park,Hong-Thuy Bui,Deug-Nam Kwon,Min-Hui Kang,Mihye Oh,Jae-Woong Han,Ssang-Goo Cho1,Chankyu Park,Hosup Shim,Hye-Min Kim,Man-Jong Kang,Jin-Ki Park,Jeong-Woong Lee,Kyung-Kwang Lee 한국동물번식학회 2012 Reproductive & Developmental Biology(Supplement) Vol.36 No.2s
In this study, we examined whether Hanganutziu-Deicher (H-D) antigens are important as an immunogenic non-a1,3-galactose (Gal) epitope in pigs with a disrupted a1,3- galactosyltransferase gene. The targeting efficiency of the AO blood genotype was achieved (2.2%) in pig fibroblast cells. A total of 1800 somatic cell nuclear transfer (SCNT) embryos were transferred to 10 recipients. One recipient developed to term and naturally delivered two piglets. The a1,3-galactosyltransferase activity in lung, liver, spleen, and testis of heterozygote a1,3-galactosyltransferase gene knockout (GalT-KO) pigs was significantly decreased, whereas brain and heart showed very low decreasing levels of a1,3- galactosyltransferase activity when compared to those of control. Enzyme-linked lectinosorbent assay showed that the heterozygote GalT-KO pig had more sialyla2,6- and sialyla2,3- linked glycan than the control. Furthermore, the heart, liver, and kidney of the heterozygote GalT-KO pig had a higher N-glycolylneuraminic acid (Neu5Gc) content than the control, whereas the lung of the heterozygote GalT-KO pig had Neu5Gc content similar to the control. Collectively, the data strongly indicated that Neu5Gc is a more critical xenoantigen to overcoming the next acute immune rejection in pig to human xenotransplantation.
Clinical Experience of Rigid Bronchoscopy in Single Center
Kim, Hyun-Jin,Kim, Sei-Won,Lee, Hye-Yeon,Kang, Hyeon-Hui,Kang, Ji-Young,Kim, Ju-Sang,Kim, Myung-Sook,Kim, Seung-Soo,Kim, Jin-Woo,Yun, Hyeong-Gyu,Kim, Chi-Hong,Kim, Kwan-Hyoung,Moon, Hwa-Sik,Cho, Kwang The Korean Academy of Tuberculosis and Respiratory 2012 Tuberculosis and Respiratory Diseases Vol.72 No.6
Background: The aim of this study was to analyze clinical situations requiring rigid bronchoscopy and evaluate usefulness of rigid bronchoscopic intervention in benign or malignant airway disorders. Methods: We retrospectively reviewed 29 patients who underwent rigid bronchoscopy from November 2007 to February 2011 at St. Paul's Hospital, The Catholic University of Korea School of Medicine. Results: Of the 29 patients, the most frequent underlying etiology was benign stenosis of trachea (n=20). Of those 20 patients, 16 had post-intubation tracheal stenosis (PITS), 2 had tracheal stenosis due to inhalation burn (IBTS) and other 2 had obstructive fibrinous tracheal pseudomembrane (OFTP). Other etiologies were airway malignancy (n=6), endobronchial stenosis due to tuberculosis (n=2), and foreign body (n=1). For treatment, silicone stent insertion was done in 16 cases of PITS and IBTS and mechanical removal was performed in 2 cases of OFTP. In 6 cases of malignant airway obstruction mechanical debulking was performed and silicone stents were inserted additionally in 2 cases. Balloon dilatation and electrocautery were used in 2 cases of endobronchial stenosis due to tuberculosis. In all cases of stent, airway obstructive symptom improved immediately. Granulation tissue formation was the most common complication. Conclusion: Tracheal stenosis was most common indication and silicone stenting was most common procedure of rigid bronchoscopy in our center. Rigid bronchoscopic procedures, at least tracheal silicone stenting, should be included in pulmonary medicine fellowship programs because it is a very effective and indispensable method to relieve critical airway obstruction which needs training to learn.
( Jin Ah Kim ),( Chang Wook Kim ),( Ji Young Kim ),( Yun Hui Kim ),( Mi Ju Cheon ),( Hee Yeon Kim ),( Jung Myung Kim ),( Yoo Dong Won ),( Se Hyun Cho ),( Jong Young Choi ),( Seung Kew Yoon ),( Nam Ik 대한간학회 2017 춘·추계 학술대회 (KASL) Vol.2017 No.1
Aims: Immune regulatory molecules such as forkhead box P3 (FoxP3), programmed death-1 (PD-1) and cytotoxic T-lymphocyte-associated protein-4 (CTLA-4) on T cell are associated with antiviral effector T cell dysfunction, which influences on T cell exhaustion and persistent viral infection in patients with chronic hepatitis C (CHC) and chronic hepatitis B (CHB). These FoxP3, PD-1 and CTLA-4 are known to up-regulated in CHC and CHB but, there is few report about the phenotypic changes of these molecules during direct-acting antiviral (DAA) therapy, especially, Daclatasvir and asunaprevir (DCV+ASV) in genotype 1b CHC. We investigated the expression of FoxP3, PD-1 and CTLA-4 during 6 months DCV+ASV treatment in 19 patients with genotype 1b CHC. Methods: Nineteen patients with genotype 1b CHC under DCV+ASV treatment were enrolled for detection of intrinsic inhibitory molecules of T cell signals (PD-1, CTLA4) and extrinsic inhibitory molecule, FoxP3. Peripheral blood mononuclear cells (PBMC) were isolated from these subjects before treatment (T0), 1 month (T1), 3 month (T3), 6 month (T6) and 9 month (T9) during DCV+ASV treatment. The expressions of FoxP3, PD-1, CTLA-4, CD8, CD4 on T cells were monitored by flow cytometry. Results: T cells from patients with CHC before DCV+ASV treatment (T0) showed increased expression of FoxP3, PD-1 and CTLA-4 compared to healthy control. However, T cells from patients with CHC under DCV+ASV treatment showed decreased expression of PD1 and CTLA-4 at T6 compared to T0 significantly. Interestingly, the expression of Foxp3 was sustained at T6 through T0. Conclusions: In CHC, PD-1 and CTLA-4 as inhibitory T cell molecules were down-regulated during 6 months DCV+ASV therapy but, FoxP3 as regulatory T cell marker was sustained during DCV+ASV therapy. This phenomenon could be one of background mechanisms of post-DAA syndrome such as HCC development or reactivation of HBV coinfection after DAA therapy.
내시경으로 확진된 위선암의 VATER 팽대부 림프선 전이 1 예
김영호,김경호,김남훈,김규식,김진범,김배영,이영록,추무엽,황교승,곽재영,이명기,조연회,이주택 대한내과학회 1997 대한내과학회지 Vol.53 No.4
Cancer of the stomach is responsible for approximately 650,000 deaths globally each year and is probably second only to lung cancer worldwide as an overall cause of cancer-related mortality. Similar to the situation with most adenocarcinomas of the gastointestinal tract, carcinomas of the stomach can spread by local extension to adjacent normal structures and can develop lymphatic, peritoneal, and distant metastases. The tumor cells, can also permeate diffusely into the lymphatic plexus of the bowel, more often at the level of the upper duodenum hut sometimes down into the distal ileum and the large bowel. We report a case of lymphatic metastasis of gastric adenocarcinoma to the ampulla of Vater with review of the literature.
Quality Evaluation on Use of Camellia Oil as an Alternative Method in Dried Seaweed Preparation
Kim, Jae Kyeom,Park, Hui Gyu,Kim, Cho Rong,Lim, Ho-Jeong,Cho, Kye Man,Choi, Jine Shang,Shin, Dong-Hoon,Shin, Eui-Cheol The Korean Society of Food Science and Nutrition 2014 Preventive Nutrition and Food Science Vol.19 No.3
The fatty acid and volatile compound compositions of camellia oil were analyzed in this study. The impacts of the replacement of conventional vegetable oil with camellia oil on the sensory attributes of dried seaweed were also determined. C18:1 (83.59%), followed by C16:0 and C18:2, were the most abundant fatty acids in camellia oil. A total of 11 and 32 volatile compounds were identified in camellia oil and sesame oil, respectively. In the preference test, the camellia oil samples received a higher, although insignificant, liking rating in overall acceptability of appearance. Overall, there were no differences between the sensory attributes of camellia oil and sesame oil. This finding, combined with the unique fatty acid composition, thermal stability, and health benefits of camellia oil indicate that further study into the use of camellia oil in foods is warranted.
김휘준 ( Kyung-sup Kim ),박길섭 ( Hui-joon Kim ),서영학 ( Kil-seop Park ),김경섭 ( Yeong-hak Seo ) 한국정보처리학회 2017 한국정보처리학회 학술대회논문집 Vol.24 No.2
본 논문은 이미지 탐지 모델인 Faster R-CNN 을 통해 영유아가 존재하는 어린이 집, 공원, 놀이터, 거실 등의 2D 이미지를 읽어 영유아에게 위험이 되는 요소를 인식해 위험상황을 감지하는 시스템을 구현하였다. 실생활에서 쉽게 구할 수 있는 데이터를 바탕으로 탐지 모델을 구현 했으며 현재 머신 러닝 분야가 음성인식과 행위데이터를 기반으로 상용화 되어있는 반면 본 모델은 이미지를 데이터로 한 탐지 모델이 다양한 서비스 분야에서 활용 될 수 있음을 보여준다.
( Hui Jung Kim ),( Kang Suk Ko ),( Sang Bae Park ),( Hyeong Il Kim ),( Yang Tong Cho ),( Woong Ji Kim ),( Byung Jun Jeon ),( Hye Min Yu ),( Min Ju Song ),( Yun Kyung Hong ),( Wan Hee Yoo ) 전북대학교 의과학연구소 2007 全北醫大論文集 Vol.31 No.2
Vascular thrombosis in the venous or arterial system is quite common in systemic lupus erythematosus(SLE), especially in patients who have active disease with vasculitis and antiphospholipid antibodies(aPL). These thrombotic events usually developed on deep veins of the lower extremities and very rarely occur on the upper extremities. The upper extremity deep vein thrombosis(UEDVT) is a relatively rare disease, constituting about 2% of all cases of deep venous thrombosis, and usually occurs axially and subclavian vein. Here, we report an unusual case of brachial and basilica vein thrombosis in a 34-yr-old woman with SLE after taking oral contraceptives for 3months before the onset of upper-extremity deep vein thrombosis(UEDVT). Venous Doppler ultrasonography and CT images showed thrombosis and thrombophlebeitis of the brachial and basilica vein of the left arm. Thrombophilia work-up including IgM and IgG anticardiolipin antibodies, lupus anticoagulant were negative. Protein C, Protein S, and antithrombin 3 levels were within normal range. The patient was started anticoagulation therapy and oral contraceptives were discontinued. After that, she was asymptomatic and she had been treated with aspirin 100mg/day.