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약물의 in vitro 투과 실험을 위한 사람의 비강점막상피세포 단층막의 일차배양
유진욱,김유선,이민기,노환중,이치호,김대덕 한국약제학회 2002 Journal of Pharmaceutical Investigation Vol.32 No.1
The primary culture of human nasal epithelial cell monolayer was performed on a Transwell. The effect of various factors on the tight junction formation was observed in order to develop an in vitro experimental system for nasal transport studies. Human nasal epithelial cells, collected from human normal inferior turbinates, were plated onto diverse inserts. After 4 days, media of the apical surface was removed for air-liquid interface (ALI) culture. Morphological characteristics was observed by transmission electron microscopy (TEM). A polyester membrane of 0.4 μm pore size was determined as the most effective insert based on the change in the transepithelial electric resistance (TEER) value as well as the ^14C-mannitol transport study. The ALI method was effective in developing the tight junction as observed in the further increase in the TEER value and reduction in the permeability coefficient (P_app) of ^14C-mannitol transport. Results of the transport study of a model drug, budesonide, showed that the primary culture system developed in this study could be further developed and applied for in vitro nasal transport studies.
화장품 유통경로에 따른 소비자 쇼핑성향, 정보원, 점포이미지에 관한 연구
선정희,유태순 한국의류학회 2004 한국의류학회지 Vol.28 No.5
The present study attempts to identify the differences in consumer information source, shopping orientation, and store image in the purchase of cosmetics in adult women at the age of 20 or more according to the distributions channels: department stores, specialty stores, discount stores and direct mails. From October 3 to 13, a survey was conducted to 1,200 adult women who visited each channel and who would understand the purpose of this study and complete the questionnaire. 300 sheets were distributed to each of the channels under investigation, and a total of 1,116 questionaaires were used in the final analysis. Using the statistical package, SPSS WIN 10.0, factor analysis, ANOVA, and Duncan's post-hoc test were carried out. The result are as follows: 1. There was a difference in the demographical characteristics of the consumers according to the distribution channels for cosmetics. 2. There was a difference in the shopping orientations of the consumers according to the distribution channels for cosmetics. 3. There was a difference in the information sources of the consumers according to the distribution channels for cosmetics. 4. There was a difference in the store images perceived by the consumers according to the distribution channels for cosmetics.
전류 비유 모델에 의한 초등학생의 전류 개념 변화 분석
유병길,강인석,김병철,남만희,박선희,소하연,윤희정,이영아,이하룡,전병문,정승호 부산교육대학교 과학교육연구소 2000 科學敎育硏究 Vol.25 No.-
There exists a major impediment to learning electricity which may illuminate why direct presentation of scientists' ideas is too aggressive a strategy. This impediment lies in thinking that electricity is used up and in envisaging the light bulb as a consumer. This view is based on a powerful idea which summarises much of our experience; it declares that 'things get used up', 'you cannot get something for nothing', and 'intuitive thinking'. To replace this view with scientific view, we made the analogy model. It is suggested that the analogy model is more effective in teaching electricity circuits than conventional teaching method.
고령토로부터 알루미나 추출에 관한 연구(Ⅱ) : 질산에 의한 추출
유대선,이희수,김정한 연세대학교 산업기술연구소 1990 논문집 Vol.22 No.2
The preparation conditions of alumina powder extracted from domestic San-Cheong Kaolin by nitric acid were investigated. The experimental conditions which have an effect on the yield of alumina were as follows ; the calcination temperature and time, the acid concentration, the reaction temperature and time, pH of the extracted solution, and particle size of the raw material. The aggolomeration of pseudo-boehmite precipitated by NH₄OH at pH 8 was controlled by various drying methods. α-Al₂O₃powder prepared by heating of the dried powder for 1 hour at 1200℃. Under the optimum condition, the yield and purity of α-Al₂O₃powder were 73.6 percent and 95.5 percent, respectively. The alumina particles prepared by the freeze drying method revealed narrower size distribution and less agglomerate than others. And impurities of the raw material which have an effect on the extraction of alumina were Kyanite and Anorthite.
아로마 요법이 뇌졸중환자의 자율신경계와 스트레스에 대한 신체 저항도에 미치는 효과
신유선,조영숙,정유진 대한기초간호자연과학회 2004 Journal of korean biological nursing science Vol.6 No.2
Purpose : The purpose of this study is to determine effects of aromatherapy on the activity and balance of autonomic nervous system and on physical resistance to stress. Methods : This research is a primitive experimental design which attempts to analyze aromatherapy EKG monitoring on real-time basis. Lavender & Chamomile, each 30 drops, were blended with 100ml Sweet Almond oil. Subjects was laid relaxed, and had insides of his wrists and ankles attached with electrodes for EKG. Right after applied with essential oil onto his philtrum and parotid, started on EKG monitoring. Results : The activities of parasympathetic and sympathetic nerve were changed as time elapsed, with significant differences(p=.000). In multiple comparison, the value was significantly different (p<.05).The balance of autonomic nerve was changed, becoming close to the normal level in accord with applicable international standards(1.5)(p=.011). In multiple comparison, the value showed a significant difference(p<.05). Physical resistance to stress increased with the passage of time, but not statistically significant. Conclusions : This suggests that aromatherapy can be used as a nursing intervention which aims at alleviating symptoms related to the imbalance of autonomic nerve system such as headache, hot flashes, irregular heartbeat, nervousness, depression and anxiety.
윤선심,김영준,유재중,이호근,김영현,임한수,박두순 순천향대학교 부설 산업기술연구소 2002 순천향 산업기술연구소논문집 Vol.8 No.1
There has been a sizable growth in the use of rich media over the World Wide Web(WWW) as more individuals and institutions realize rich-media's potential in a broad range of applications, including electronic commerce, education and training, news, etc. Internet and WWW technologies provide the information of the web. Libraries are systems that carry out interactions among information and knowledge seekers. Library become more and more important for the provision of data. Total information system for books management exist in many forms. We present total information system for books management which is applied to several different sources, e.g., administrator security login, statistics about the present state of lending, printing management, and convenient GUI(Graphic User Interface) environment.
시각 커뮤니케이션으로서의 패션 일러스트레이션에 관한 연구 : 은유와 환유를 중심으로 Based on Metaphor and Metonymy
최정화,유영선 한국의류산업학회 2003 한국의류산업학회지 Vol.5 No.2
The purpose of this study is to analyze the expression and possibility of metaphor and metonymy as a visual communication means in the history of fashion illustration. The findings of this study were as follows : The 20th century ago, fashion illustration has shown a metaphor and metonymy in caricature and image drawing. From the 1900 to 1929, it has shown a metonymy in omission, figure's one part and metaphor in significant elements, colors, image dissection, parody, etc. From the 1930 to 1959, it has shown a metaphor in figure's substitution by surrealism and metonymy in simplification. From the 1960 the 1979, it has shown a metaphor in illusion and collage. Since 1980, it has shown a metaphor in figure's transformation, distortion, combination of different kinds by postmodernism.
유건우,이선희,임수정,박형진,김태신,송은식,송근호 忠南大學校 獸醫科大學 附設 動物醫科學硏究所 2009 動物醫科學硏究誌 Vol.16 No.1
A 6 years old Schunauzer dog (7.2kg, intact female) with history of hematuria for two days was referred to the Veterinary Medical Teaching Hospital of Chungnam National University. Complete blood cell count showed no significant abnormalities and serum chemistry profile showed increased phosphate profile. On urinanalysis, there was evidence of bacterial infection. On ultrasonographic evaluation, irregular renal contour and increased echogenecity, pelvic and uretral dilation, and thickening of urinary bladder wall were observed. Based on these finding, the dog was diagnosed as pyelonephritis. The dog was treated with antibiotics based on antimicrobial susceptibility test results, then successfully resolved after 8 weeks of treatment.
RP-HPLC에서 α-Hydroxy Carboxylic Acid류의 머무름거동에 관한 연구
문선영,김정수,유은아 성신여자대학교기초과학연구소 1996 基礎科學硏究誌 Vol.15 No.-
This study is an investigation of the effect of organic modifier volume in mobile phase, temperature and pH on the retention behavior in RP-HPLC. The retention data, capacity factors(k') of ten α-hydroxy acids were measured in the mobile phase with various compostion of methanol-phosphate buffer solution(v/v) at the same time that pH value was adjusted to 2.4, 4.4 and 6.4 respectively, and regulated the temperature from 10°C to 50°C with using c18 column. As expected, the decrease in retention time was mostly obtained as higher pH values than pKa values of solutes. That is explained by the increasing concentration of the ionized species when pH increase, but some of them did not coincide with that tendency. The effect of temperature on retention was investigated by the linerity of van't Hoff plot (R〉0.900), on the whole, at a lower volume fraction of organic modifier. And hydrophobicity index, log kw' obtained with experimental and the theoretical method showed an excellent correlation. Maximum retention time of these solutes is Mostly no more than double that of dead time, therefore another hydrophobicity index φ0 values were determined and discussed in several solute system.