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      • KCI등재

        한국인 사체에서의 정상 종골의 실측: 예비보고

        김정한,곽희철,김전교,정양환,Kim, Jung-Han,Gwak, Heui-Chul,Kim, Jeon-Gyo,Jung, Yang Hwan 대한족부족관절학회 2014 대한족부족관절학회지 Vol.18 No.1

        Purpose: The purpose of this report is to evaluate the measured values of normal Korean calcaneus by conduct of a cadaveric study. Materials and Methods: A total of 42 calcanei were obtained from Korean cadavers. A digital goniometer was used for measurement of B$\ddot{o}$hler's angle, Gissane angle, posterior facet articular inclination angle, and Fowler-Philip angle of calcaneus. A vernier caliper was used for measurement of the maximal antero-posterior length, maximal transverse width, and maximal height of calcaneus. Results: The average B$\ddot{o}$hler's angle, Gissane angle, posterior facet articular inclination angle, and Fowler-Philip angle was $32.3^{\circ}{\pm}5.0^{\circ}$, $114.4^{\circ}{\pm}8.2^{\circ}$, $61.2^{\circ}{\pm}4.4^{\circ}$, and $60.3^{\circ}{\pm}7.6^{\circ}$. The average maximal antero-posterior length, maximal transverse width, and maximal height of calcaneus was $74.2{\pm}3.0mm$, $43.0{\pm}4.0mm$, and $42.5{\pm}3.0mm$. Conclusion: The measured values of normal Korean calcaneus were lower than the values reported in the international literature. Therefore, development of appropriate instruments reflecting the anatomical characteristics of Koreans will be needed.

      • KCI등재

        Isoguanosine과 Berberine 1 : 1 혼합물의 항암효과

        김정한,이상준,한영복,문정조,김종배,Kim, Jung-Han,Lee, Sang-Jun,Han, Young-Bok,Moon, Jung-Jo,Kim, Jong-Bae 대한약학회 1994 약학회지 Vol.38 No.2

        Isoguanosine and berberine 1:1 mixture[l:[1(mole:mole)] has been prepared and evaluated by measuring antitumor effects against various tumor cell lines in culture and in mice. We reported that the synergistic effect of isoguanosine and berberine mixture has been revealed compared with each of isoguanosine and berberine increased by $3{\sim}8$ times than that of each components in various tumor cell lines in vitro. The most effective dose of isoguanosine and berberine mixture was 60 mg/kg/day in mice bearing S-180 solid tumor, the %(1-T/C) values were 70%. Against the P-388 leukemia, isoguanosine-berberine mixture was the most effective at the dose of 60 mg/kg/day, the %T/C values were 163%.

      • KCI등재

        족근골 유합의 발생 빈도: 단일 기관 자기공명영상 분석

        김정한,곽희철,이창락,김영준,김전교,이선주,이정한,박준호,Kim, Jung-Han,Gwak, Heui-Chul,Lee, Chang-Rak,Kim, Young-Jun,Kim, Jeon-Gyo,Lee, Sun-Joo,Lee, Jeong-Han,Park, Jun-Ho 대한족부족관절학회 2016 대한족부족관절학회지 Vol.20 No.3

        Purpose: Tarsal coalition results from defects during the developmental stage and produes ankle pain and limitations in the range of motions. Its incidence has been reported to be 1%, but there has not been any reports with respect to Koreans. Therefore, we evaluated the prevalence of tarsal coalition in Koreans. Materials and Methods: Between 2005 and 2014, we analyzed a total of 733 cases of foot and ankle magnetic resonance imaging (MRI) in our hospital. There were 391 men and 342 women. All MRI readings were read by a radiologist in our hospital. We classified the coalitions in accordance with the histological and anatomical characteristics, and calculated the prevalence in each group. Moreover, we tried to determine the prevalence of tarsal coalitions in accordance with sex, age, and proportion of the symptomatic tarsal coalitions. Results: There were a total of 11 MRIs of tarsal coalition - 9 talocalcaneal coalitions, 1 calcaneocuboidal coalition, and 1 calcaneonavicular coalition. Nine tarsal coalitions were observed in men and 2 in women. Conclusion: Through this study, we found that the prevalence of tarsal coalition, including the asymptomatic patients, is similar to the previously known prevalence (1%). By getting more MRIs of the foot and ankle, we could better represent the prevalence of tarsal coalitions in Koreans.

      • KCI등재

        시퀀셜 로테이션 분배기 구조를 이용한 X-band 마이크로스트립 4×4 광대역 원형 편파 배열 안테나

        김정한,김중관,김용진,이홍민,Kim, Jung-Han,Kim, Joong-Kwan,Kim, Yong-Jin,Lee, Hong-Min 한국전자파학회 2007 한국전자파학회논문지 Vol.18 No.2

        본 논문은 X-band에서 동작하는 마이크로스트립 원형 편파 $4{\times}4$ 배열 안테나의 설계와 제작에 대해 다룬다. 단일 안테나는 정사각형 패치를 사용하고 비대칭 십자 개구 결합 급전 구조를 사용하여 RHCP(Right Handed Crcularly Polarization)로 동작하도록 하였다. 기존의 배열 안테나의 소자간의 간격을 0.8 ${\lambda}_0$에서 0.45 ${\lambda}_0$로 간격을 줄여 실장 면적을 감소시켰다. 급전 선로는 시퀀셜 로테이션 분배기로 $2{\times}2$ 배열 안테나를 설계하여 양호한 이득과 축비 대역폭을 나타내었다 ${\lambda}/4$ Transformer와 T-junction 전력 분배기로 $4{\times}4$ 배열 안테나로 확장하였다. 시뮬레이션으로 확인한 결과 최대 방사 이득은 15.09 dBi로 나타났으며, 축비 대역폭은 3 dB 기준 $9.05{\sim}10.4$ GHz(13.5%)의 양호한 특성을 보였다. 제작된 $4{\times}4$배열 안테나는 10 GHz에서 측정 결과 임피던스 대역폭($VSWR{\leq}2$)은 $8.45{\sim}11.84$ GHz(33.9%)로 나타났으며, 최대방사 이득은 11.10 dBi를 얻었다. 또한 측정된 축비 대역폭은 $9.42{\sim}10.47$ GHz(10.5%)를 얻었다. In this paper, the circularly polarized $4{\times}4$ array antenna is proposed for the X-band. A single antenna consists of square patch and unequal cross-aperture coupled feeding. The RHCP(Right Handed Circularly Polarization) is generated by unequal cross-aperture coupled feeding. By reducing space among elements of way antenna from 0.8 ${\lambda}_0$ to 0.45 ${\lambda}_0$, the mounting area of array antenna is miniaturized. The $2{\times}2$ array antenna is designed using sequential rotation feeding network. The good level of gain, axial ratio, and impedance bandwidth are achieved. The $4{\times}4$ array antenna is extended by ${\lambda}/4$ transformer and T-junction power divider. The simulated maximum radiation gain is 15.09 dBi at 10 GHz. The simulated 3 dB Axial Ratio bandwidth is from 9.05 to 10.4 GHz(13.5%). Also the measured impedance bandwidth($VSWR{\leq}2$) of manufactured $4{\times}4$ array antenna is from 8.45 to 11.84 GHz(33.9%). The measured maximum radiation gain is 11.10 dBi at 10 GHz. The measured 3 dB Axial Ratio bandwidth is from 9.42 to 10.47 GHz(10.5%).

      • KCI등재

        종골의 사체 실측 결과와 방사선학적 측정 결과의 비교

        김정한,곽희철,이창락,정동우,노상명,Kim, Jung-Han,Gwak, Heui-Chul,Lee, Chang-Rack,Jeong, Dong-Woo,Roh, Sang-Myung 대한족부족관절학회 2015 대한족부족관절학회지 Vol.1 No.2

        Purpose: We wanted to compare the results between cadaveric and radiological measurements of calcaneus. Materials and Methods: Sixty three calcaneus of 33 cadavers donated between December 2012 and December 2014 were actually measured. Computed tomography (CT) images of 244 calcaneus in 122 patients of the same age group with cadavers were radiologically measured. Maximum length, maximum width, maximum height, $B{\ddot{o}}hler$ angle, Gissane angle, Fowler-Phillip angle, and tala-articular angle were measured. Results: In cadaveric measurement, the mean maximal height, length, and width were $41.8{\pm}3.3mm$, $73.3{\pm}3.4mm$, and $40.7{\pm}2.2mm$, respectively. In radiological measurement, the mean maximal height, length, and width were $38.5{\pm}4.3mm$, $74.0{\pm}5.7mm$, and $44.7{\pm}1.4mm$, respectively. In cadaveric measurement, the mean $B\ddot{o}hler$ angle, Gissane angle, Fowler-Phillip angle, and tala-articular angle were $32.1^{\circ}{\pm}6.2^{\circ}$, $110.8^{\circ}{\pm}8.1^{\circ}$, $55.8^{\circ}{\pm}6.8^{\circ}$, and $59.7^{\circ}{\pm}4.6^{\circ}$, respectively. In radiological measurement the mean $B{\ddot{o}}hler$ angle, Gissane angle, Fowler-Phillip angle, and tala-articular angle were $32.6^{\circ}{\pm}3.8^{\circ}$, $113.7^{\circ}{\pm}5.7^{\circ}$, $62.2^{\circ}{\pm}3.9^{\circ}$, and $61.6^{\circ}{\pm}6.3^{\circ}$, respectively. The mean maximal height was significantly higher in the cadaveric measurement group (p<0.001) and the mean maximal length and width were significantly higher in the radiologic measurement group (p<0.001, p<0.001). The mean Gissane angle, Fowler-Philip angle, and $B{\ddot{o}}hler$ angle were significantly higher in the CT group (p=0.001, p<0.001, p=0.016, respectively). There was no significant difference in the mean tala-articular angle (p=0.352). Conclusion: Significant differences in length parameters were observed between the cadaveric measurement group and the radiologic measurement group. However, no significant differences in angular measurements were observed between the two groups. The authors carefully conclude that radiological measurement values may be different from actual values in the calcaneus.

      • KCI등재

        다중기기 취약도곡선의 지진상관계수 조합 절차

        김정한,김시영,최인길,Kim, Jung Han,Kim, Si Young,Choi, In-Kil 한국지진공학회 2020 한국지진공학회논문집 Vol.24 No.3

        For the important safety system, two or more units of identical equipment or redundant components with similar function were installed to prevent abnormal failure. If the failure probability of such equipment is independent, this redundancy could increase the system safety remarkably. However, if the failure of each component is highly correlated by installing in a structure or experiencing an earthquake event, the expected redundancy effect will decrease. Therefore, the seismic correlation of the equipment should be evaluated quantitatively for the seismic probabilistic safety assessment. The correlation effect can be explained in the procedure of constructing fragility curves. In this study, several methodologies to quantify the seismic correlation in the failure probability calculation for multiple components were reviewed and two possible ways considering the realistic situation were selected. Simple examples were tested to check the applicability of these methods. The conversion method between these two methods was suggested to render the evaluation using the advantages of each method possible.

      • SCOPUSKCI등재
      • KCI등재후보

        갑상선 수질암 환자에서 칼시토닌 정상화와 관련된 예후인자

        김정한,김상욱,남석진,서정민,양정현,Jeong-Han Kim,M.D.,Sang-wook Kim,M.D.,Seok-Jin Nam,M.D.,Jeong-meen Seo,M.D. and Jung-Hyun Yang,M.D. 대한갑상선-내분비외과학회 2003 The Koreran journal of Endocrine Surgery Vol.3 No.2

        Purpose: Medullary thyroid carcinoma (MTC) is an uncommon thyroid tumor. Calcitonin (CT) is a very specific marker of this cancer and has a major place in the postoperative follow-up. The aim of this study was to evaluate the outcome of surgical treatment for MTC and to identify the prognostic factors for the normalization of CT after surgery. Methods: Retrospective analysis of 29 patients with MTC from 1994 to 2002 in Samsung Medical Center was carried out. Results: 22 female and 7 male were identified and their mean age was 46.9 years. Mean follow-up was 42.7 months. 5 patients had MEN2a; all had pheochromocytoma and 2 among them had hyperplasia of parathyroid gland. The majority of patients (86.2%) presented with a palpable neck mass and 23 patients were diagnosed with MTC preoperatively. Total thyroidectomy with or without neck dissection was performed in all patients. Cervical lymph node involvement was detected in 34.5% of these patients. Basal CT levels were found to be normal in 15 patients (51.7%) postoperatively. 1 distant metastasis, 6 loco-regional metastases and 1 death were observed during follow-up period. Overall survival rate was 94.7% and disease-free survival rate was 62.9% at 5 years. Univariate analysis showed that extra-thyroidal invasion and involvement of lymph node were significant prognostic factors for normalization of CT after surgery. Conclusion: Considering the high recurrence rate in the thyroid bed and cervical lymph node, more extensive and thorough neck dissection is needed for the treatment of MTC. (Korean J Endocrine Surg 2003;3:121-126)

      • KCI등재후보

        부신 질환에 대한 외과적 치료의 최근 경향

        김정한,Jung-Han Kim,M.D. 대한갑상선-내분비외과학회 2011 The Koreran journal of Endocrine Surgery Vol.11 No.4

        Laparoscopic adrenalectomy (LA) has become the standard for the management of benign adrenal tumors since Gagner reported a successful surgery in 1992. Conventional open adrenalectomies have been replaced by LA because of significant advantages such as reduced wound pain and hospital stays, decreased transfusion requirements, and postoperative complications. In addition to the development of laparoscopic surgery, robot-assisted adrenalectomies are gaining popularity worldwide. The robotic system offers several advantages: it magnifies a surgeon's view with 3D optics, offers excellent resolution and depth perception, and the robotic wrists offer 7 degrees of freedom, allowing for precise movements. Another new technique of laparoscopic adrenal surgery is single-port surgery, which is an effort to reduce the number of trocars and their related wound complications. Although this is technically more difficult compared to conventional laparoscopic surgeries, patients are satisfied with a single-site scar and reduced pain. In this paper, the recent development of new techniques in adrenal surgery are introduced and their specific advantages and disadvantages are discussed. Also, this article reviews the clinical results of a partial adrenalectomy for small benign adrenal tumors and adrenalectomies for single adrenal metastasis from extra-adrenal malignancy. (Korean J Endocrine Surg 2011;11:229-233)

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