접합면의 차이에 따른 두개골 외판의 생존

박성근,송중원,한기환,강진성,박관규 大韓成形外科學會 1991 Archives of Plastic Surgery Vol.18 No.3

Onlay graft of the calvarial bone has been popularized in craniofacial surgery because absorption of the calvarial bone is less than that of the endochondral bone. But the problems with using the calvarial bone are its rigidity and difficulty in setting a precise apposition. When the outer tables of the calvarial bone are used for augmentation and reconstruction of the convex zygoma, forehead, or chin, it is better to place the cancellous surface over the convex recipient bone to get a precise apposition. Whereas, it is better to place the cortical surface over the concave nose or orbital cavity to achieve a good apposition. Therfore, our study was designed to determine the differences of bone absorption and regeneration between cancellous and cortial bone contact to facial bone, and between preserved periosteum and detached periosteum in autograft of calvarial bone in dog models. Outer tables of the calvarial bone were placed in subperiosteal pockets of the upper and lower maxilla in four different ways : Group I ; The cancellous surface was placed in contact with the bare recipient bone, and the cortical surface attached with periosteum was accordingly contacted with the elevated periosteum of the recipient bone. Group Ⅱ ; The corical surface attached with periosteum was placed in contact with the bare recipient bone and the cancellous surface was contacted with the elevated periosteum of the recipient bone, Group Ⅲ ; The arrangenent was similar to Group Ⅰ except that the periosteum of the graft was deprived. Group Ⅳ ; The arrangement was similar to Group Ⅱ except that the periosteum of the graft was deprived. Volume measurements using a caliper technique and histological study were made 20 weeks postoperatively. The volume of maintenance is as follows ; Group Ⅰ, 84.2% ; Group Ⅱ, 77.6% ; Group Ⅲ, 77.0%, and Group Ⅳ, 69.5%. The histolgical contribution of living bone was assessed by a modified point counting technique : Group Ⅰ, 86.6%, Group Ⅱ, 83.8% ; Group Ⅲ, 79.6% and Group Ⅳ, 77.6%. Greater volume maintenance and histological contribution of living bone were found when cancelllous surface rather that the cortical were placed in contact with the recipient bone and the grafts from their periosteum were preserved. We concluded that in order to expect better survival of a grafted bone, the cancellous surface of the graft should contact with the recipient bone and that the periosteum of the graft should be preserved.

23년간 서울 지역 초˙중˙고등학생의 비만 추이

박영신,이동환,최중명,강윤주,김종희 대한소아과학회 2004 小兒科 Vol.47 No.3

Pocine Adenovirus-3의 E1B Region의 鹽基序列 分析

朴鍾賢,宋載永,李重馥,玄芳勳,安東濬,車相昊,裵用泰,姜永源,Reddy, P S,全茂炯,安壽煥 충남대학교 생물공학연구소 1999 생물공학연구지 Vol.7 No.-

돼지 아데노바이러스(PAV-3). 6618주의 EIB region이 包含되어 있는 map unit 4.0에서 9.7까지의 유전자에 대한 1,984 bp의 염기서열을 決定하였으며, 이 結果를 알려진 여러 아데노바이러스 유전자와 비교하여 다음과 같은 결과를 얻었다. 1. PAV-3의 EIB유전자는 10개의 ORF로 구성되어 있으며, 그 중 아데노바이러스의 단백질과 유사성이 있는 것은 ORF1, ORF2 및 ORF3이었다. ORF1은 Ad41의 19kd 와 BAV-2에서의 EIB ORF2에서의 아미노산의 一致率은 각각 32%와 31%이었다. 2. ORF2는 Ad2 55kd protein과 tupaia adenovirus 44kd protein가 각각 34%로 아미노산 一致率이 가장 높았으며, Ad41의 52kd protein. BAV-3의 EIB ORF3에서도 33%의 一致率을 보였다. 3. ORF1은 61-666 uncleotide (606 bp), ORF 2에서는 429-1,850 uncleotide (1,422 bp)의 부위로 각각 202, 474 a.a로 構成되었으며, 예상되는 분자량은 20 kd와 52 kd이었다. 4. ORF3는 hexon-associated pIX유전자로 추정되며 내부에 1개의 polyadenylation signal(ATAAA)이 1938-1942 uncleotide에 위치하였으며, 이 부위는 TATA box (1937-1942 uncleotide)와 중복되어 존재하였다. Porcine adenovirus type 3 (PAV-3) does not cause severe infection in pigs. Adenovirus has been suggestive of live vaccine vector carrying foreign gene. One of insertion regions is delayed early (EIB) region. However, EIB region of PAV-3 has not been molecularly characterized to date. Nucleotide sequence of EIB of PAV-3 was determined. The EIB region was composed of 1,984 bp and located between 4.0 and 9.7 map units. Three potential open reading frames(ORFs) with low level of homology to other adenoviruses and a polyadenylation signal were identified in the rightward direction of genome. The nucleotide and the predicted amino acid sequences of EIB were compared to those of human and animal adenoviruses. One of the three potential ORFs. ORF1 encoded a polypeptide homologous to bovine adenovirus type 2(BAV-2) ORF2 and human adenovirus type 41(Ad41) 19 kd protein. ORF2 encoded a polypeptide homologous to human adenovirus type 2(Ad2) 55 kd protein, bovine adenovirus type 3(BAV-3) ORF3 and porcine adenovirus type 4(PAV-4) ORF2. The predicted protein of ORF1 had homology to those of Ad41 and BAV-2 with 32 and 31% respectively, whereas the deduced protein of ORF2 had homology to those of Ad2. BAV-3 and PAV-4 with 34, 33 and 29%, respectively.

백제 금석문(金石文) 자료의 분류와 형태적 분석

박중환 국립중앙박물관·한국고고미술연구소 2008 동원학술논문집 Vol.9 No.-

백제의 역사와 문화는 기록이 부족하여, 연구에 있어서 문헌기록 이외의 기록 자료들이 갖는 중요성이 매우 크다. 이 글은 백제의 금석문 자료들을 통하여 백제사의 전개 과정을 새로운 각도에서 바라보기 위해 백제 금석문 자료를 전체적으로 조망하는 작업을 진행하고자 하였다. 백제 금석문을 이해하기 위해서는 먼저 연구 대상이 될 수 있는 자료를 분류하고 분석하는 작업이 필요하다. 금석문에서 얻을 수 있는 가장 중요한 정보는 물론 명문의 내용이 되겠지만 유물들의 구성과 기능, 분포, 재질, 명문 기법, 외형적 특징 또한 명문 내용을 이해하는 데 간과할 수 없는 정보를 제공해줄 수 있다. 이러한 측면을 고려하여 이 글에서는 금석문의 외형적 특징들을 검토해보고자 하였다. 그 결과 명문 기법은 음각과 양각, 압인, 묵서, 상감 등 다양한 방법들이 사용되었지만 음각에 의한 방법이 가장 일반적임을 알 수 있었다. 백제 유일의 금상감 금석문 자료인 칠지도의 경우, 금사(金絲)가 구(溝)에서 탈락되지 않게 하는 보강 작업이 이뤄지지 않은 미발달된 상감 기법이 사용되었던 것으로 알려지고 있다. 이러한 상감 기술의 미숙성은 이 금석문 자료가 금상감을 이용하여 만든 가장 초기 단계의 유물임을 말해준다. Limitations follow in investigating the history and the culture of Baekje due to a lack of documents. Owing to this lack of resources, apart from written records, other documental resources such as epigraphs are immensely important. As for the marking techniques of the Baekje epigraph, various methods such as the incision, relief, stamp, calligraphy and inlay techniques were used. However, the most generally used technique would have been the incision method. Among the incision methods, there were unique calligraphic engraving techniques that may be called the square-hand printed style characters or sword-engraved inscriptions. For example, Baekje’s unique gold-inlaid epigraph, the sword with seven branches , is believed to have used the underdeveloped inlaid technique without the supplementary work in order that the gold thread would not peel off from the groove. This kind of immature inlaid technique proves that the epigraph material was an artifact that has been made with the use of a gold inlay technique at the most early stage.

한국인 안검의 생체계측지

박동만,송중원,한기환,강진성 大韓成形外科學會 1990 Archives of Plastic Surgery Vol.17 No.5

Plastic surgeons who frequently deal with trauma and deformity of the eyelids and orbits, need have an abundant knowledge of the accurate anatomical morphology and acceptable proportion of them. The normal value of the anatomical morphology and function of the eyelid has not yet been standardized in Korea. The authors measured anthropometry of normal Korean eyelids and statistically analysed in 2,151 individuals including 1,078 male and 1,073 female. Statistical analysis of these measurements offers valuable information about the chronological growth, size, and shape of healthy Korean eyelids. The results are as follows : 1. There was no significant statistical difference between the right and left sides in all measurements. 2. The growth of the eyelid reached the adult level at about 20 years of age and then the growth can be divided into 3 patterns, the first one slowly increased, the seconded one was a stationary, and the last one slowly decreased. 3. The following statistics were recorded for males and females. The cornea-lateral canthal distance was 7.9mm and 7.3mm, the diameter of the cornea was 13.8mm and 13.6mm cornea-medial canthal distance was 7.8mm and 7.5mm the horizontal dimension of the palpebral fissure was 29.7mm and 28.4mm, the vertical dimension of the palperbral fissure was 7.9mm and 8.0mm, the slant of the palperbral fissure was 9.5 degrees an 10.6 degrees, the intercanthal distance was 36.5mm and 37.2mm, the width of the glabella was 24.4mm,. and 24.1mm, the interpupillary distance was 66.1mm and 63.9mm, the ectocanthion-superior margin of the palpebral fissure distance was 14.9mm and 14.2mm, the endocanthion-superior margin of the palpebral fissure distance was 14.9mm and 14.2mm, the height of the opened upper eyelid was 10.3mm and 10.0mm, the height of the closed upper eyelid was 18.2mm and 18.1mm, levator function by the Berke's method was 16.2mm and 15.6mm, MLD was 7.2mm and 7.1mm, and MRD1, was 2.7mm and 2.6mm respectively. 4. The vertical dimension of the palpebral fissure, slant of the palpebral fissure, and height of the double eyelid fold were greater in females than males. The intercanthal distance and width of the glabella was nearly the same in males and females and other measurements were greater in males than females. 5. A double eyelid fold was seen in about 36% of males and 50% of females. The average height of the double eyelid fold with the eye closed in 20 year old females was 5.2mm and 30 to 50 year old females was 5.5mm. The most frequent shape of the double eyelid fold was type 5. 6. The epicanthus was present in 58.1% in this series and existed in over 90% under age 10, but disappeared in about 90% of the people over 50. The most frequent shape of the epicanthus was tarsalis type.

단결정 Si(111) 위에 형성된 Ti-실리사이드에 대한 RBS 및 XRD 분석

이중환,권오준,최치규,박동수,김건호,이상환,이의완,곽호원 濟州大學校 基礎科學硏究所 1991 基礎科學硏究 Vol.4 No.1

초고진공 상태에서 p형 Si(111)기판에 Ti을 증착한 후 고진공에서 열처리하여 Ti-실리사이드를 형성시켰으며, Ti-실리사이드의 상전이 및 형성운동학은 2 MeV⁴He? 이온 후방산란과 x-선 회절방법으로 규명하였다. 형성된 TiSi₂는 결정학적으로 C49(ZrSi₂)와 C54 구조의 두 종류로 확인되었다. C49 TiSi₂상은 열처리온도가 700℃이하의 저온에서 형성되었고, 700℃ 이상의 고온에서는 C54 TiSi₂상으로 나타났다. 본 연구에서 확인된 C54 TiSi₂전이온도(??)는 700℃ 였고, TiSi₂형성온도 영역내에서 TiSi₂ 층두께(χ)와 열처리시간(t)의 관계는 저온(700℃ 이하)일 경우 ??이고, 고온(750℃ 이상)에서는 χ=ct+d 의 관계식이 만족됨을 알 수 있었다. 이것은 700℃ 이하에서 TiSi₂ 형성기구가 Si 확산에 의해 제어되며, 750℃ 이상에서는 핵형성 제어에 의하여 계면반응하는 것으로 나타났다. Titanium silicides were prepared by depositing titanium film on p-type Si(111) followed by annealing in ultra high vacuum. The growth kinetics of Ti-silicide has been studied by using ion backscattering spectrometry and x-ray diffractometry. Two crystallographic structures of Ti-silicide were identified the (ZrSi₂)structure and C54. The C49 TiSi₂ phase was formed at low annealing temperature(<700℃),and it transformed to the C54 phase over 700℃. The relation between the thickness of TiSi₂ layer(χ) and the annealing time(t) was ?? when annealing temperature was under 700℃ and χ=ct+d when that was over 750℃. The former implied that the formation of TiSi₂ was controlled by diffusion and the latter by nucleation of at the Ti/Si(111) interface.

전두사골 수막뇌류 및 Saethre-Chotzen증후군에 의한 안와격리증의 치험

송중원,한기환,박성근,강진성 大韓成形外科學會 1991 Archives of Plastic Surgery Vol.18 No.2

본 교실에서는 전두사골 수막뇌류에 의한 안와격리증 2례는 두개내 접근으로 수막뇌류 절제술을 실시함과 동시에 두 개외 접근으로 안와내벽 및 외벽 절골술로써 교정하였으며 Saethre-Chotzen 후군에 의한 1례는 두개골 성형술과 U형 절골술로 교정하여 비교적 만족할 만한 결과를 얻을 수 있었기에 보고하는 바이다. The authors experienced two cases of mild hypertelorism with frontoethmoidal meningoencephalocele and one with Saethre-Chotzen syndrome. The first and second cases, which had nasofrontal and nasoethmoidal meningoencephalocele respectively, were corrected by resection of the meningoencephalocele, repair of the dura, and calvarial bone graft intracranially, and combined medial and lateral orbital wall osteotomy with augmentation rhinoplasty with calvarial bone grafts extracranially. To stabilize the orbital contents medially, a split osteotomy of the lateral orbital wall and interpositional bone graft were done in order to avoid step deformity of the lateral orbital rim. The third case, Saethre-Chotzen syndrome characterized brachycephaly, hypertelorism, ptosis of the eye lid, maxillary hypoplasia, lower set frontral hair line, and partial cutaneous syndactyly was corrected by a Modified Marchac technique for remodelling the forehead and a subcranial U-osteotomy for mild hypertelorism. Maxillary hypoplasia was corrected effectively by advancement on the medial portion of the U-shaped bony segment. Augmentaton rhinoplasty with calvarial bone graft and chip bone grafts on the anterior nasal spine was done simultaneously. A large amount of nasal bone grafts in two cases were absorbed, and then augmentation rhinoplasty using silicone implant was performed after 6 months, 12 months respectively. In mild hypertelorism with associated deformity, a extranial osteotomy with augmentation rhinoplasty and correction of associated deformities can offer good aesthetic results.

거대적아구성빈혈의 임상적 고찰

곽승근,천재민,박남숙,박상은,박수진,윤환중,김삼용,조덕연 충남대학교 의학연구소 2003 충남의대잡지 Vol.30 No.2

Megaloblastic anemias are disorders caused by impaired DNA synthesis and chara-cterized by the presence of megaloblastic cells. Clinical data on these disorders in Korea are limited. The aim of this study was to analyze clinical characteristics of megaloblastic anemias caused by vitamin B12 deficiency. We identified 40 cases who were diagnosed as megaloblastic anemia from January 1993 to December 2002 in a retrospective study on the basis of chart review. We investigated the annual distribution of diagnosed patients, clinical manifestations and response to treatment. 19 cases were complicated with a previous total gastrectomy(gastrectomy group) and 21 cases had no history of surgical operation(non-gastrectomy group). The most common presenting complaint was generalized weakness. The median age at diagnosis was 7(range: 38-79) years in non-gastrectomy group. The mean pos-toperative duration was 7(range: 4-25)years in group of total gastrectomy and mean level of serum vitamin B12 was lower than 100 pg/mL in both group. Peripheral blood revealed thrombocy-topenia, macrocytic anemia and hypersegmented neutrophil in all cases. After treatment of pareliteral vitamin B12, Their clinical symptoms and hematologic findings improved except two patients who had bone marrow with lower cellularity. Cobalamin replacement after total gastrectomy is still missing. Diagnoses are made too late in a population of patients, resulting in irreversible neurological sequale, and we suggest that Pernicious anemia seems not to be very rare in Korea.

溫室保溫커튼의 材料特性에 따른 保溫效果分析

金榮福,金容換,李昇揆,金成泰,羅又禎,閔永鳳,朴重春,崔東烈 慶尙大學校 1991 論文集 Vol.30 No.2

The effects of the material properties of thermal curtains upon reduction of the greenhouse heat loss were studied. A theoretical analysis procedure with equations and computer programs was developed to estimate them by using energy balance principles. Curtain effectiveness for every three kinds pf value level of the material properties were studied and compared. The results of this study would be useful for the developent and management of greenhouse thermal curtains.

어류 성장에 있어서 식물 및 동물플랑크톤의 먹이기여도

김백호,김미연,최환석,김정중,최민규,박승택,정연태,高村典子 원광대학교 환경과학연구소 2000 環境科學硏究誌 Vol.9 No.1