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Paraquat 처리에 의한 Bacillus megaterium의 Superoxide dismutase 활성저해
최경호,김춘숙,유지선 대구효성가톨릭대학교 1993 연구논문집 Vol.46 No.1
The effect of paraquat (1, 1'-dimethyl-4,4'-dipyridilium dichloride) treatment on activity of microbial superoxide dismutase(SOD), a key enzyme which protects the organism from toxicity of oxygen, was investigated. Exponentially growing cells of Bαcillus megaterium(ATCC 1987) were treated with 1.OmM paraquat by cultivation in the concomitant presence of the paraquat. Paraquat-treated culture showed a linear decrease in turbidity, cellular weight and vidable cell counts while those of control culture showed a linear increase until nine hours of cultivation. After nine hours of cultivation, turbidity(0.68), dry cell weight(1.19mg/ml) and viable cell counts(5.0×19?cells/ml) of the treated culture reached to approximately 62%, 83% and 4% of those of initial, respectively. Paraquat-treated culture(in vivo) showed a SOD activity of 0.68unit/ml and a specific activity of 1.79unit/mg protein after nine hours of cultivation. These values were equel to 22% and 44% of the control culture, respectively. When enzymes were liberated from sonic-disruptured cells(in vitro) by orderly using of sodium phosphate buffer, buffered lysoyme and triton X-100, paraguat-treated culture showed an increased activity of the engyme, while control culture did not show any significant increase of the enzyme activity. Activities of SOD drastically decreased as increasing the paraquat concentration in the crude enzyme lysate, although protein content was not significantly varied. The lysate dissolved 1.0mM paraquat showed a specific activity of SOD decreased to 45% of control lysate. It was noticed that the decreasing rate was approximately similar to that of the lysate prepared from paraquat-treated cells.
장형윤,이선구,김경란,이수영,박진영,김은주,강지인,이은,안석균 大韓神經精神醫學會 2009 신경정신의학 Vol.48 No.1
Objectives We studied the psychometric properties of a Korean version of the Ambiguous Intentions Hostility Questionnaire (K-AIHQ), which measures hostile social-cognitive biases for use in the research on paranoia. Methods The translation and back-translation of the AIHQ with concern for the cultural differences were done according to the standard procedure. A sample of 83 healthy volunteers completed the K-AIHQ. Results The scores of the K-AIHQ were comparable to the results of the original studies. The Paranoia Scale was correlated with the K-AIHQ, but Magical Ideation and Perceptual Aberration scales were not correlated with the K-AIHQ. The interrater reliabilities of the items in each situation were in the acceptable range. Conclusion The KAIHQ seems to be a reliable and valid test to measure the hostile social Cognitive biases of patients with paranoia.
내시경역행성담췌관조영술 후 발생한 종격동기종, 피하공기증, 긴장성 기흉 1예
조용건,이현승,권균홍,김자영,김봉진,김지연,배용목,박선자 고신대학교의과대학 2008 고신대학교 의과대학 학술지 Vol.23 No.4
However, Endoscopic retrograde cholangiopancreatography (ERCP) is still helpful procedure for the diagonosis of the pancreatobiliary disease and treatment through endoscopic sphinterectomy (EST) is relatively safe, these have possiblity of complications such as hemorrhage, infection, panceatitis, and perforation. ERCP related perforation was rarely reported in 0.3 to 1.1% of previous study, but most serious complication. A report of Pneumomediastinum, Tension Pneumothorax complicating perforation after ERCP and EST is very uncommon. In our hospital, we experienced case of pneumomediastinum, subcutaneous emphysema, and tension pneumothorax after ERCP and EST, and the patient (a 58 years old female with suspicious common bile duct stone) was treated successfully with conservative treatment.
이준식,박성한,홍현진,안광순,김지연,배용목,이은영,박선자 고신대학교의과대학 2007 고신대학교 의과대학 학술지 Vol.22 No.2
Juvenile polyp, also known as a retention polyp because they contain mucin cysts, is a relatively common hamartomatous lesion in chlidhood. It occurs in 1-2% of children and young adults; however it is uncommon in adulthood. Juvenile polyp is rare in the first year of life and is thus presumed to be acquired and not congenital. It is pedunculated, 2-3 cm in size, red-tan in colour, smooth and always shows fluid filled cystic spaces on cut surface. Histologically, Juvenile polyps are hamartomatous with distended, mucus-filled glands, often with cystic dilatation and edematous lamina propria containing abundant vasculature. The most common manifestation is rectal bleeding produced by auto-amputation of the polyp. Juvenile polyp has been considered not to be at increased risk of developing carcinoma. However, atypical epithelium is observed in some lesions, especially in larger polyps, which may give rise to adenoma and subsequent malignant transformation. Therefore the diagnosis of solitary juvenile polyp should not be made only with colonoscopy and biopsy, but should be totally resected endoscopically for pathologic evaluation. About 90% of the lesions are solitary and localized within 20cm from anal verge. In Korea, there are some reports of juvenile polyps located in the rectosigmoid colon. We report one case of juvenile polyp in adolescent that presented as a hematochezia & abdominal pain, which is located at right colon.
20대 여성의 정장의류 상표군 선호도와 구매시 평가기준
권수애,장현주,한정혜,조소영,손지희,김선화,안경은 충북대학교 교육 ·생활연구소 생활과학연구센터 2002 생활과학연구논총 Vol.6 No.2
This study is to analyze the compitition structure and the brand image of the formalwear and the preferance of the brand group among the age of 20's females. The 207 samples of 20's females who live in Cheong-Ju city. The results of this study are followed as: The market competition structre appeared in positioning map have been constituted into four groups of the "Tomboy y'sb","lollol·selly·besti-belly","VOV·o.z.o.c·Joinus",EnC·i.n.v.u". The brand-trasfer of each group may easily be taken place as each compition among these groups was much feeble. By investigating the image of the formalwear brands appeared in positioning map, it may be presented that horizontality dimrnsion is "cute-ellegance image", and verticality dimension is "mannish-feminine image". Group Ⅳ such as EnC·i.n.v.u is brand which are prefered and purechaseed by the age of 20's females, whereas the preferance and puechase of brand such as VOV·o.z.o.c·Joinus.
Socioeconomic burden of sugar-sweetened beverages consumption in Korea
Jee-Seon Shim,Nam Hoon Kang,Jung Sug Lee,Ki Nam Kim,Hae Kyung Chung,Hae Rang Chung,Hung-Ju Kim,Yoon-Sook Ahn,Moon-Jeong Chang 한국영양학회 2019 Nutrition Research and Practice Vol.13 No.2
BACKGROUND/OBJECTIVES: Excessive sugar consumption may increase the risk for development of several diseases. Although average dietary sugar intake of Koreans is within the recommended level, an increasing trend has been found in all age groups. This study aimed to evaluate the population attributable fractions (PAF) to dietary sugar for disease and death in Korea, and to estimate the socioeconomic effects of a reduction in dietary sugar. MATERIALS/METHODS: The prevalence of sugar-sweetened beverages (SSB) overconsumption (≥ 20 g of sugar from beverages) was analyzed using the Korean National Health and Nutrition Examination Survey 2015. Disease-specific relative risks of excessive SSB consumption were obtained through reviewing previous studies. Using the prevalence of SSB overconsumption and each relative risk, PAFs for morbidity and mortality were calculated. Socioeconomic costs of diseases and death attributable to SSB overconsumption were estimated by using representative data on national medical expenditures, health insurance statistics, employment information, and previous reports. RESULTS: Disease-specific PAF to SSB consumption ranged from 3.11% for stroke to 9.05% for obesity and dental caries, respectively. Costs from disease caused by SSB overconsumption was estimated at 594 billion won in 2015. About 39 billion won was estimated to be from SSB consumption-related deaths, and a total of 633 billion won was predicted to have been saved through preventing SSB overconsumption. CONCLUSIONS: Sugars overconsumption causes considerable public burdens, although the cost estimates do not include any informal expenditure. Information on these socioeconomic effects helps both health professionals and policy makers to create and to implement programs for reducing sugar consumption.
Kim, Jee Seon,Kim, Taek Gyung,Kong, Won Ho,Park, Tae Gwan,Nam, Yoon Sung The Royal Society of Chemistry 2012 Chemical communications Vol.48 No.74
<P>A nanoporous membrane is coated with catechol-tethered poly(<I>N</I>-isopropylacrylamide). The thermosensitive variation of surface wettability determines the hindered diffusivity of dextran (40 kDa) through the nanopores.</P> <P>Graphic Abstract</P><P>A nanoporous membrane coated with catechol-tethered poly(<I>N</I>-isopropylacrylamide) regulates the diffusivity of macromolecules <I>via</I> thermally controlled wettability. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=c2cc32233a'> </P>