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이은,조현주,홍수종,이진아,성흥섭,유진호 대한소아청소년과학회 2017 Clinical and Experimental Pediatrics (CEP) Vol.60 No.5
Purpose: Macrolide resistance rate of Mycoplasma pneumoniae has rapidly increased in children. Studies on the clinical features between macrolide susceptible-M. pneumoniae (MSMP) and macrolide resistant-M. pneumoniae (MRMP) are lacking. The aim of this study was to identify the macrolide resistance rate of M. pneumoniae in Korean children with M. pneumoniae penupmonia in 2015 and compare manifestations between MSMP and MRMP. Methods: Among 122 children (0–18 years old) diagnosed with M. pneumoniae pneumonia, 95 children with the results of macrolide sensitivity test were included in this study. Clinical manifestations were acquired using retrospective medical records. Results: The macrolide resistant rate of M. pneumoniae was 87.2% (82 of 94 patients) in children with M. pneumoniae pneumonia. One patient showed a mixed type of wild type and A2063G mutation in 23S rRNA of M. pneumoniae. There were no significant differences in clinical, laboratory, and radiologic findings between the MSMP and MRMP groups at the first visit to our hospital. The time interval between initiation of macrolide and defervescence was significantly longer in the MRMP group (4.9±3.3 vs. 2.8±3.1 days, P=0.039). Conclusion: The macrolide resistant rate of M. pneumoniae is very high in children with M. pneumoniae pneumonia in Korea. The clinical manifestations of MRMP are similar to MSMP except for the defervescence period after administration of macrolide. Continuous monitoring of the occurrence and antimicrobial susceptibility of MRMP is required to control its spread and establish strategies for treating second-line antibiotic resistant M. pneumoniae infection.
이은,이준무,Lee, Eun,Lee, Joon-Moo 대한약침학회 2005 Journal of pharmacopuncture Vol.8 No.1
Effects of Samhwangsasimtang aqua-acupuncture at gansoo($B_{18}$) and chungwan($CV_{12}$) on antihyperlipidemic and antioxidant were investigated in rat fed high fat diet. Concentrations of triglyceride, free fatty acids, lipoprotein and glucose in plasma showed a tendency to decrease in the aqua-acupuncture groups. In plasma lipid composition, total cholesterol and LDL- cholesterol showed a tendency to decrease in aqua-acupuncture groups, however the values of HDL-cholesterol showed no significantly different in the treatment groups. Concentration of thiobarbituric acid reactive substances(TBARS) in plasma and liver showed a low in the aqua-acupuncture groups. The values of glutathione peroxidase(GSH-Px) and catalase(CAT) activity showed a tendency to increase in aqua-acupuncture groups. However the values of superoxide dismutase(SOD) activity showed no significantly different in the treatment groups.
이은 대한에이즈예방협회 2004 레드리본 Vol.61 No.-
1980년대 이후로 에이즈가 전 인류의 보건문제로 떠오르면서 우리나라에서도 감염자 수가 급격히 늘어나게 되었다. 전국적으로는 1999년에 이미 1000명, 2002년엔 2000명을 넘어섰으며 2004년 9월 현재에는 2,994명의 에이즈 감염자가 확인되었다. 광주광역시는 서울과 부산에 비해 그 수는 적지만 1987년 첫 환자 발생 후 계속적으로 늘어나고 있고, 모든 연령층에서 발생하고 있으며 성생활과 밀접한 관련이 있다는 것을 고려한다면 그 관리와 예방이 무엇보다도 중요하리라 본다.
근위축성 측삭 경화증에서 Riluzole과 한방 병행치료에 대한 고찰
이은,고흥,박병욱,Lee, Eun,Ko, Heung,Park, Byung-Wook 대한한방내과학회 2001 大韓韓方內科學會誌 Vol.22 No.2
We had one female ALS patient. The patient was diagnosed with ALS by EMG and Symptoms. We diagnosed the patient as Jinshang(筋傷) and Pishenyangxu(脾腎陽虛). We gave Shaoyaogancao-tang jiami(芍藥甘草湯加味) and Sijunzi-tang he Lizhong-tang jiami(四君子合理中湯加味) based on the differentiation of symtoms. We report the changes of the ALS patient's disphagia, lalopathy, and hypotonia after two months treatment with Riluzole and oriental medical treatment.