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오재화,김우혁,최웅 朝鮮大學校 建設技術硏究所 2004 建設技術硏究 Vol.24 No.2
Recently, cities are to be a new limelight in developing countries. Because, They have performed important roles in promoting and spreading economic and social development of the country. This study is concerned with all cities in Korea, and has three main purposes. First one is to select the general analysis variables affecting urban growth from existing theoretical literatures. Second one is to identify the dominant factors and their changes for the growth of cities in Korea through the analysis of correlation with growth rate. It could be done by case study of growth trends of all existing cities for analysis period. The last one is to find out a formula to estimate the future growth of cities in Korea. The results of this study could offer much suggestions to establish the development strategies of cities in Korea.
조현이,정종철,김호성,최재욱,성대경,서지훈,김성범,이계혁 大韓顎顔面成形再建外科學會 2000 Maxillofacial Plastic Reconstructive Surgery Vol.22 No.1
Osteosarcoma is a primary malignant tumor arising most often in the long bone, but rare in jaw bone. Especially osteogenic sarcoma of the mandible is a rare tumor, comprising less than 0.5% of all head and neck tumors. Osteosarcoma occurs cheifly in young persons, and presenting very survival rates. Histopathologically this tumor can be classified three types, osteoblastic, fibroblastic, chondroblastic and classified from low grade to high grade by anaplasia or mitosis of the tumor cells. Sometimes, the exact diagnosis of osteosarcoma is difficult especially in low grade osteosarcoma, even if clinical or radiographical findings suggest to osteosarcoma. So suspcious to malignant bone tumor in clinical or radiological findings, biopsy should be taked from deep portion and multiple area, and sharing the patient history and radiographs with pathologist will assist in the development of the diagnosis. We report a case of low grade osteosarcoma on the mandible initially difficulty in accurate diagnosis. The patient visited our hospital for routine dental treatment but radiographic findings displayed ill-defined radiolucency with osteoid formation on the mandible. Final diagnosis was difficulty in initial biopsy but subsequent biopsy taked from deep portion presented infiltrative growth and mitosis of the tumor cell in some area with small osteoid bone formation, so we could reach final diagnosis as low grade sarcoma. We treated this patient with bloc resection of the mandible and immediate reconstruction with iliac corticocancellous block.
Jae Hyeok Choi,Jong Won Hong 대한수부외과학회 2022 대한수부외과학회지 Vol.27 No.3
Harlequin ichthyosis (HI) is a rare congenital disease that primarily affects the skin. Its complications include syndactyly, which can cause severe constriction. Surgical release is thought to be helpful, but the details remain unclear due to a lack of data. We share our 5-year experience of a patient with HI with successful outcomes from five syndactyly release operations involving division, local flap interposition, and full-thickness skin grafts. A visible decrease in the ulnar deviation of the metacarpophalangeal joints and a wider range of motion were noted. There were no complications, except for one case of donor site dehiscence that was resolved after minor revision. The surgical design must conform to the anatomical structure, as it can be easily mistaken due to masking of the skin. A suitable donor site is a flat, non-folding surface, such as the lateral thigh.
Choi, Hyeok-Jae,Ito, Takuya,Yokogawa, Masashi,Kaneko, Shingo,Suyama, Yoshihisa,Isagi, Yuji The Korean Society of Plant Taxonomists 2017 식물 분류학회지 Vol.47 No.1
The population status of Hydrangea luteovenosa Koidz. in Korea was investigated, with an emphasis on its genetic diversity. From field surveys, we obtained the only locality record for a wild population in Jeju Island, which contained 285 individuals in total. Genotyping was performed using five microsatellite markers for the all extant plants in Korea. Three Japanese populations were also genotyped for the comparative analyses. The genotyping result showed that the Jeju population consisted of only two multilocus genotypes, including identical heterozygous genotypes at two loci; it had been maintained mostly by vegetative reproduction; and although the Jeju population is geographically far from Japanese populations, all alleles observed in the Korean population were shared with Japanese populations, suggesting the possibility that H. luteovenosa in the Jeju Island had been recently migrated or introduced from Japan. Future ecological and genetic studies associated with negative effects of low genetic variation will be essential for determining the conservation direction of the threatened Korean population of this species.
Choi, Ji Na,Choi, Yun-Hyeok,Lee, Jeong-Min,Noh, Ill Chan,Park, Jae Won,Choi, Wahn Soo,Choi, Jung Ho Taylor Francis Health Sciences 2012 NATURAL PRODUCT RESEARCH Vol.26 No.24
<P>Trachelospermum jasminoides (Apocynaceae) has pharmacological effects that include anti-inflammatory, anti-bacterial and anti-viral activities, which have been observed from various studies. Of these pharmacological effects, the anti-inflammatory capacity of compounds from T. jasminoides is not yet known exactly. In this study, we investigated the compound that can be used for the suppression of lipopolysacchaide (LPS) stimulated inflammatory responses in macrophages among the five isolated compounds. β-sitosterol-β-D-glucoside (1) was found to reduce nitric oxide (NO) production from LPS-induced RAW 264.7 cells the most. In addition, compound 1 strongly inhibited the interleukin 6 (IL-6) activities of stimulated macrophages. Treatment of RAW 264.7 cells with compound 1 reduced secretion of inflammatory elements including tumour necrosis factor - alpha (TNF-α) and interleukin 1 beta (IL-1β). Thus, compound 1 may be a useful candidate for the development of new drugs to treat endotoxemia and inflammation accompanied by the overproduction of NO.</P>
Cytotoxic Isoquinoline Alkaloids from the Aerial Parts of Corydalis incisa
Choi, Sang-Un,Baek, Nam-In,Kim, Sung-Hoon,Yang, Jae-Heon,Eun, Jae-Soon,Shin, Tae-Yong,Lim, Jong-Pil,Lee, Jae-Hyeok,Jeon, Hoon,Yun, Mi-Young,Leem, Kang-Hyun,Park, Hee-Wook,Kim, Dae-Keun 대한약학회 2007 Archives of Pharmacal Research Vol.30 No.2
Three known isoquinoline alkaloids were isolated from the chloroform-soluble fraction of the methanolic extract of the aerial parts of Corydalis incisa (Papaveraceae) through repeated column chromatography. Their chemical structures were elucidated as corynoline (1), corynoloxine (2) and 6-oxocorynoline (3) using spectroscopic analysis. Compounds 1-3 exhibited cytotoxicity against human A549, SK-OV-3, SK-MEL-2 and HCT 15 tumor cells.