소아 혈중 연농도에 관한 조사

이용환,이덕희,김진하,박인근,한태영,장세한 大韓産業醫學會 1995 대한직업환경의학회지 Vol.7 No.1

지리적 위치에 따라 소아들에 있어서 혈중 연농도에 차이가 있는지의 여부와 소아들의 혈중 연농도의 참고치 계산을 위한 기초자료를 얻기 위하여 6-8세의 도심지역 거주 소아 102명과 교외지역 거주 86명, 총 188명을 대상으로 조사하여 다음과 같은 결과를 얻었다. 1. 전체 소아들의 평균혈중 연농도는 산술평균이 7.24, 기하평균이 6.92 ㎍/100㎖이었으며 남자가 여자보다 통계적으로 유의하게 더 높았다(p<0.05). 2. 도심지역과 교외지역 거주 소아들의 혈중 연농도는 도심지역거주 소아가 남, 녀 모두에서 교외지역 거주 소아보다 통계적으로 유의하게 더 높았다(p<0.05). 3. 혈중 연농도에 따른 분포에서는 <5 ㎍/100㎖군에 조사대상자 188명의 17.02%가 분포되었고 도심지역(5.88%)보다 교외지역(30.23%)에서 더 많은 분포를 보였으며, 10 ㎍/100㎖이상 군에는 전체 소아의 12.23%가 분포하고 있었으며, 도심지역(20.59%)이 교외지역(2.33%)보다 더 많이 분포하고 있었다. 이상의 결과에서 볼 때 도심지역 거주 소아들에 대한 연폭로의 관리대책이 시급히 마련되어야 할 것으로 판단된다. The authors conducted this study to evaluate some differences in blood lead levels between inner-city and suburban children and obtain the basic data of the reference value of the blood lead concentrations in children. The subjects were composed of 102 children residing in inner-city and 86 children in suburban. Their age range were 6 to 8 years old and the obtained results were as follows; 1. The arithmetic means of the blood lead level in male and female, male, and female children were 7.24, 7.40, 7.08 ㎍/100㎖, and geometric means were 6.92, 7.08, 6.76㎍/100㎖, respectively. 2. The children residing in inner-city had the higher blood lead levels both male and female than suburban children with statistical significance(p<0.05) 3. Seventeen percent of the total subjects had lead concentrations < 5 ㎍/100㎖, and 5.88% of inner-city children and 30.23% of suburban children had this lead values. But in ≥10㎍/100㎖ group, the inner-city children(20.39%) were more distributed than suburban children(2.33%), and 12.33% of total subjects had this lead values.

경주지역 여고생의 초경과 체성장간의 관계

김준섭,권오구,박진석,오종수,박정현,박제식,안세한,이용환,서정호,신태섭,최영배,김덕수,이관,박수경 東國大學校醫學硏究所 2002 東國醫學 Vol.9 No.1

본 연구는 경주지역 1개 고등학교 3학년 여고생을 대상으로 초경 시작 전인 초등학교 4학년부터 고등학교 2학년까지의 키, 몸무게, 가슴둘레 수치와 초경 연령을 파악하여 여성의 초경이 빠를수록 체성장 속도의 변화가 있을 것이라는 가설을 기초로 두 요인간의 관련성을 파악하고자 시행되었다. 경주시 1개 여자고등학교 3학년생 총 317명에 대해 ㅊ경 나이, 초경시 심리 상태, 초경이 시작되었을 때의 상담 여부와 상담하였던 사람, 부모 신장과 초경전후의 식사 규칙성, 다이어트 경험, 수면시간, 스트레스, 음주/흡연 여부, 질병력 등에 대한 설문 조사를 시행하였고, 초등학교 4학년부터 고등학교 2학년까지의 키, 몸무게, 가슴둘레에 대한 정보는 건강기록부에서 확보하였다. 상기 대상자 중 건강기록부가 분실된 39명, 초경나이에 대해 응답하지 않았던 29명 및 결석 등으로 조사를 하지 못하였던 42명을 제외한 조사 대상자는 206명으로 선정하였다. 대상자들의 초경연령 평균값(Mean±SD)은 13.0±1.11이었고, 초등학교 4학년부터 고등학교 2학년까지의 초경 이후 신장 성장률은 감소하였으며, 초경연령이 빠른 군이 초등학교 때는 신장에 있어서 우위를 차지하나 고등학교에 오면서 신장은 비슷한 수준이 되었다. 초경후 1-2년 사이에 체중과 흉위의 증가율은 감소하였고, 초경연령이 빠른 군이 초등학교와 고등학교 사이에 체중과 흉위에서 모두 우위를 차지하였다. 본 연구의 결과는, 흔히 이차 성징의 시작 시점 혹은 사춘기의 시작 시점으로 보고있는 초경 연령이 청소년기의 성장과 밀접한 관련성이 있고, 특히 체중과 흉위의 성장 속도와 밀접한 관련성이 있음을 시사한다. To understand the onset of menarche in relation to changes in physical growth that take place during female adolescence, especially the changes in height and weight velocity. The 207 senior in one women high school of Kyongju were investigated in April 3 to 8, 2001. We collected the information, relation in the age at menarche, height & weight of parents, regularity of eating, and obesity diet, duration of sleeping, sickness & stress near age at menarche, by self-recording. The status of height, weight & chest circumference between the 4th grade of primary school and the junior of high school was collected by individual Health Record. The results were followed; The average age at menarche was 12.95±1.11 years old and the most frequent age of menarche is 13 years. After menarche, the velocity of height, weight and chest circumference were decreased. The most rapid group of menarche hold dominant position in height during elementary school. As time passed, they dont hold dominant position in height. The most rapid group of menarche get an advantage in the weight and the girth of chest after elementary school. The height of subjects is directly proportional to the height of their parents. These results suggest that the starting age at menestuation can be closely associated with physical growth and development.

주상 변압기의 고주파 모델에 관한 연구

한병덕(Han Byung-Duk),오정환(Oh Jung-Hwan),임태훈(Lim Tae-Hoon),김현종(Kim Hyun-Jong),임춘백(Lim Choon-Baek),김한수(Kim Han-Soo),김재철(Kim Jae-Chul) 대한전기학회 2000 대한전기학회 학술대회 논문집 Vol.2000 No.7

Anti-Helicobacter pylori Activity and Structure-Activity Relationships of Berberine Derivatives

Han, Yeong-Hwan,Lee, Kap-Duk,Lee, Dong-Ung Korean Chemical Society 2009 Bulletin of the Korean Chemical Society Vol.30 No.12

(Ln([20]DOTA)(NO₃)(H₂O)]²+(Ln=Pr³+, Sm³+, Gd³+, Dy³+) 착이온과 두자리 보조리간드(주게원자 ; N 혹은 O) 간의 화학평형

韓忠勳,李南昊,鄭德商,卞種轍,李又煥 濟州大學校 基礎科學硏究所 1999 基礎科學硏究 Vol.12 No.1

2-hydroxy-3-hydroxymethyl-5-methylbenzaldehyde(HHMMB)와 ethylenediamine 혹은 1, 3- diaminopropane의 축합반응에 의해 6-배위 칸막이 리간드 H₄L[A]와 H₄L[B]를 각각 얻은 후에 거대비고리 리간드 착물, Cu(H₂L[A])·H₂O, Cu(H₂L[B])·H₂O, CuFe(L[A])(NO₃)·4H₂O, CuFe(L[B])(NO₃)·4H₂O, [CuGd(H₂L[A])(NO₃)₂](NO₃)·2CH₃OH, [CuGd(H₂L[B])(NO₃)₂](NO₃)·2CH₃OH를 합성하였다. 2, 6-diformyl-p-cresol(DFPC)로부터 합성한 Ln-거대고리([20]DOTA)착물, [Ln([20]DOTA)(NO₃)(H₂O)](NO₃)·χH₂O{Ln(Ⅲ)=Pr, Sm, Gd, Dy}를 methanol용매에 2일 정도 정치함으로써 [Ln([20]DOTA)(NO₃)(CH₃OH]²+ 을 얻을 수 있다. 이 lanthanide[20]DOTA착물에서 배위된 CH₃OH이 주게원자가 N 혹은 O인 두자리 보조리간드, La(=0-phenylenediamine, 1, 10-phenanthroline, ethylenediamine, oxalic acid, malonic acid, acethylaceton)에 의해 치환될 때 평형상수(K)를 25℃ μ=0.1M NaClO₄에서 분광학적 방법으로 결정하였다. 보조리간드의 pKa는 o-phenylenediamine <1, 10-phenanthroline < ethylenediamine, oaxlic acid < malonic acid < acethylacetone이며, 이때 평형상수, K는 ethylenediamine < 1, 10-phenanthroline < o-phenylenediamine, acethylacetone < malonic acid < oxalic acid 경향으로 변하였다. Macroacyclic transition metal complexes such as Cu(H₂L[A])·H₂O, Cu(H₂L[B])·H₂O, CuFe(L[A])(NO₃)·4H₂O, CuFe(L[B])(NO₃)·4H₂O,[CuGd(H₂L[A])(NO₃)₂](NO₃)·2CH₃OH,[CuGd(H₂L[B])(NO₃)₂](NO₃)·2CH₃OH were prepared from the correponding hexadentate compartmental ligands, H₄L[A] and H₄L[B], which were obtained by the condensation of 2-hydroxy-3-hydroxymethyl-5-methylbenzaldehyde (HHMMB) and ethylenediamine or 1, 3-diaminopropane. Ln-macrocyclic([20]DOTA) complex, [Ln([20]DOTA)(NO₃)(H₂O)] (NO₃)₂·χH₂O{Ln(Ⅲ)=Pr, Sm, Gd, Dy}, which had been synthesized from 2, 6-diformyl-p-cresol(DFPC), was placed in methanol for 2 days, and (Ln([20]DOTA)(NO₃)(CH₃OH)]²+ was formed. The equilibrium constants (K) for the substitution of coordinated CH₃OH in the Ln-[20]DOTA complexes by various bidentate auxiliary ligands, La(=0-phenylenediamine, 1,10-phenanthroline, ethylenediamine, oxalic acid, malonic acid, acethylacetone) were determined by spectroscopic method at 25℃ and 0.1M NaClO₄. The pKa of auxiliary ligands is in the order of o-phenylenediamine < 1, 10-phenanthroline < ethylenediamine, oaxlic acid < malonic acid < acethylacetone, however the equilibrium constant(K) has shown the trend of ethylenediamine < 1, 10-phenanthroline < ethylenediamine oxalic and < malonic acid < acethylacetone, however the equilibrium costant(K) has shown the trend of ethylenediamine < 1, 10-phenanthroline < o-phenlenediamine, acethylacetone < malonic acid < oxalic acid.

Assessment of Pregnancy Outcome in IUGR Fetuses, using the Doppler Flow Velocimetry of the Umbilical and Middle Cerebral Arteries

( Han Gu Cho ),( Hwan Kyu Park ),( Beom Seok Choi ),( Sung Nam Cho ),( Jong Duk Kim ) 대한산부인과학회 1995 대한산부인과학회 학술대회 Vol.75 No.-

정상 소아들의 혈중 연 농도와 지능지수와의 관련성

이덕희,이용환,김진하,박인근,한태영,장세한 고신대학교 의과대학 1995 고신대학교의과대학부설연구소논문집 Vol.1 No.-

초등학교 교사의 체육과 지도 능력에 대한 연구

김덕천,김정식,박문환,박기호,한철언 순천향대학교 기초과학연구소 1997 순천향자연과학연구 논문집 Vol.3 No.2

This research intends to suggest a guideline for physical education by evaluating teaching abilities of both experienced male teachers and novice male and female teachers in elementary school. A survey was conducted for this purpose and the questionnaire is made up of total 38 questions with Likert's five scale of measurement. The self administration method is used and the data is processed in SAS package(Window ver 6.11). The followings are the results of the research : First. Experienced teachers are superior to novice male and female teachers in every factor except for that of faculty. Second. Novice female teachers excel in the factor of faculty, instruction and knowledge while novice male teachers in factor of research, attitude and effort. Third. The reciprocal factors in elementary school teachers' physical education are as follows : the factor of research is related to that of attitude and knowledge : the factor of attitude is that of knowledge and effort : the factor of faculty is that of knowledge. Fourth. The result of analysing teaching abilities of physical education by the factor and the group, and analysing the factor and the group's reciprocal action with two - way ANOVA appeared significantly as follows : the factor relation was in the order of attitude, effort, faculty, instruction, research, knowledge, and the group relation was in the order of experienced teachers, novice female teachers, novice male teachers. Fifth. As a result of analyzing teaching abilities of the physical education by the group, novice female male teacher as well as experienced teachers were worthy of notice. Novice female teachers were shown in the order of instruction, research, knowledge, faculty, effort, attitude, and novice male teachers were in the order of knowledge, attitude, research, effort, faculty. Experienced teachers were in the order of knowledge, research, faculty, instruction, effort, attitude. Sixth. The result of analysing teaching abilities of physical education by the factor with one - way ANOVA was that attitude, instruction, and effort were not significant, but research, faculty, and knowledge appeared as noteworthy factors.

상악동 편평세포암종에 대한 상악절제술의 치료 결과

정한신(Han Sin Jeong),손영익(Young Ik Son),정만기(Man ki Chung),민진영(Jin Young Min),오재원(Jae Won Oh),홍상덕(Sang Duk Hong),이현석(Hyun Seok Lee),백정환(Chung Hwan Baek) 대한두경부종양학회 2006 대한두경부 종양학회지 Vol.22 No.1

Background and Objectives: Maxillectomy is the mainstay of treatment for malignant tumors of the maxillary sinus(MS). Nevertheless, few have been reported on the surgical outcomes of maxillectomy for malignant tumors of MS in Korean literature. Based on our clinical experience, the authors aimed to present the treatment outcomes of maxillectomy for squamous cell carcinomas(SCC) of MS. Subjects and Methods: We reviewed the medical records of 26 cases of maxillectomies with see of MS, who were treated from 1995 to 2004 at Samsung Medical Center. Most patients(73.1%) were locally advanced stage(T3 or T4a) at initial presentation. Total maxillectomy was performed in 18 cases, which is the most frequent procedure(69.2%). We analyzed the treatment outcomes of see of MS and several variables includeing tumor stage and resection margin to identify predictors for treatment failure after maxillectomy. Follow-up duration ranged from 7 to 89 months with a mean of 33 months. Results: Treatment failure occurred in 7 cases(26.9%), among which 3 were salvaged. Three of 26 maxillectomies(11.5%) showed the positive or close(less than 5mm) resection margin in their posterior resection sites; however it did not coincide with the site of recurrence after radiation therapy. Among patients who had been followed up for more than 6 months, disease-free 3 year survival rate was 100.0% in T1 and T2, 76.2% in T3, 60% in T4a, and 69.6% in total. Conclusion: Even though most of see of MS were detected at locally advanced stage, maxillectomy with or without postoperative radiation therapy for resectable MS see(T1-T4a) provided the acceptable treatment outcome(70%, 3Y disease-free survival rate).

Jejunal varix bleeding with extrahepatic portal vein obstruction after pylorus-preserving pancreatoduodenectomy

Seung Duk Lee,Sang-Jae Park,Hyun Boem Kim,Sung-Sik Han,Seong Hoon Kim,Tae Suk You,Young-Kyu Kim,Seong Yeon Cho,Soon-Ae Lee,Young Hwan Ko,Eun Kyung Hong 한국간담췌외과학회 2012 한국간담췌외과학회지 Vol.16 No.1

We present 2 patients showing afferent jejunal varix bleeding around hepaticojejunostomy caused by extrahepatic portal vein obstruction after pylorus-preserving pancreatoduodenectomy (PPPD). The case 1 was a 58-year-old woman who had recurrent anemia and hematochezia 3 years after undergoing PPPD. On the portography, the main portal vein was obliterated and collaterals around hepaticojejunostomy were developed. After percutaneous transhepatic balloon dilatation and stent placement through the obliterated portal vein, jejunal varices had disappeared and thereafter no bleeding occurred for 32 months. The case 2 was a 71-year-old man who had frequent melena 7 years after PPPD. Portal stent insertion was first tried, but failed due to severe stenosis of the main portal vein. Therefore, meso-caval shunt operation was attempted in order to reduce the variceal flow. Although an episode of a small amount of melena occurred one month after the shunt operation, there was no occurrence of bleeding for the next 8 months. For the treatment of jejunal varices, a less invasive approach, such as the angiographic intervention of stent insertion, balloon dilatation, or embolization is recommended first. Surgical operations, such as a shunt or resection of the jejunal rim, could be considered when noninvasive approaches have failed. (Korean J Hepatobiliary Pancreat Surg 2012;16:37-42)