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      • KCI등재

        감즙염색이 직물의 태에 미치는 영향

        고은숙,이혜선 한국의류학회 2003 한국의류학회지 Vol.27 No.8

        In this study, a change of hand of fabrics dyed with persimmon juice was measured using Kawabata Evaluation System. Using cotton fabrics, linen fabric and silk fabric used frequently for persimmon juice dyeing, we examined the changes of physical properties and hand according to persimmon juice dyeing and washing. The dynamic characteristics of hand were measured tensile, shear, bending, compression, surface properties, thickness and weight. Linearity of load-extention and tensile resilience were increased in all kinds of fabrics after dyeing. Tensil energy decreased in cotton fabric 2(gauze), cotton fabric 3(muslin) and linen fabric. Shear stiffness and hysteresis of shear increased in most of fabrics. Bending rigidity of the bending property and hysteresis of bending, linearity of compression of the compression property, compression energy and compression resilience increased in all kinds of fabrics after dyeing. Thickness and weight increased much in all kinds of fabrics after dyeing. In the primary hand value, stiffness and anti-drape stiffness increased in all ind of fabrics after dyeing. The fullness and softness, crispness, scrooping felling and flexibility with soft feeling decreased. As the stiffness after persimmons dyeing increase, it was suitable for clothes material of summer.

      • KCI등재

        유아교사관련 학위논문의 경향 분석

        고선미,박은혜 이화여자대학교 교육과학연구소 2000 교육과학연구 Vol.31 No.3

        본 연구는 유아교사관련 논문을 연구문제별로 그 내용과 변인을 분석함으로서 현재까지 이루어진 유아교사에 관한 연구 동향의 기초 자료를 제공하고 앞으로 유아교사 관련 논문의 바람직한 연구방향을 함께 제시하는 것을 목적으로 하였다. 1974년부터 1999년 2월까지 발표된 석·박사 학위논문 중 유아교사와 관련된 총 292개 논문의 연구문제 976개를 분석한 결과 다음과 같은 결과를 얻었다. 첫째, 교사교육에 영향을 주는 요인과 교사의 행동이 연결된 연구가 가장 많았으나 교사교육과정에 대한 연구는 미흡하며 교사교육과정에 영향을 주는 요인과 교사교육과정 및 교사의 행동이 모두 연결된 연구는 거의 이루어지지 않았다. 둘째, 유아교사에 관한 학위논문에서 사용된 연구 변인은 개인적 변인이 기관 변인보다는 조금 더 많이 사용되었다. 개인적 변인은 인구통계학적인 외적 요인에 편중되어 있으며, 기고나 변인은 설립유형 및 기관유형 등에 편중되어 있었다. The purpose of this study was to analyze the trends in master´s thesis and doctoral dissertations in the area of early childhood teacher education.292 master´s thesis and doctoral dissertations published between 1972 and 1999 were analyzed according to Yarger and Smith(1990)´s category.Data were processed with a frequency and percentage were calculated.The results are as follows.First, most of the research were conducted to investigate the area of antecedent conditions, outcomes, or antecedent conditions,-outcomes relationships.But, much fewere research were done on the area of process.Special trends in the research questions in terms of period were not found.The second, personal research variables are more used than institutional research variables.Among the personal research variables, career, academic career, age, marriage status were the most frequently used.Among the institutional variables, kinds of establishments (public/private), the kinds of institution (kindergarten/ nursery/ day care center elementary school), the number of children, the number of class were most frequently used.

      • 정서유발단어에 대한 주의이동시 뇌신경망의 활성 양상

        김연희,장은혜,고명환,신승훈,양경혜,손진훈 한국뇌학회 2002 한국뇌학회지 Vol.2 No.2

        본 연구는 fMRI를 사용하여 정서유발단어에 의한 주의이동과 관련한 뇌신경망을 규명하기 위하여 12명의 오른손잡이 여대생을 대상으로 수행하였다. fMRI 실험을 위한 뇌활성화 과제는 예비실험을 통하여 선정된 행복, 슬픔, 위협에 해당하는 각각 36개씩의 단어와 각 단어의 짝을 이루기 위한 중성단어를 이용하여 변형된 Posner 패러다임을 블록디자인으로 고안하였다. fMRI 영상은 1.5T Simens Vision scanner를 사용하여 실시하였으며, single-shot EPI 기법으로(TR/TE:3840/40ms, flip angle: 90, FOV: 220, 64x64 matrix, Slice thickness: 6mm) 이미지를 얻었고 피험자의 반응시간을 기록하였다. 자료분석은 SPM-99 소프트웨어를 사용하였다. 정서유발단어는 중성단어에 비하여 반응시간이 의미있게 빨라 효과적인 주의이동이 일어났음을 알 수 있었다. 정서유발단어와 중성단어에 의한 뇌활성화 상태를 감산분석한 결과, 좌측 상두정엽, 양측 후두엽 및 소뇌에서 뇌활성화를 보였고, 이들 영역은 정서유발단어에 의한 주의이동시 특징적으로 활성이 일어나는 뇌영역임을 보여주었다. 또한 여러 가지 정서가를 가진 단어에 의해 유발되는 주의의 정도가 특징적인 신경망의 활성과 관련되어 있음을 알 수 있었다. The purpose of this study is to delineate the neural network related to the shift of attention and its modulation by emotion-provoking words using functional MRI (fMRI). Twelve right-handed normal female volunteers participated in fMRI study. Their mean age was 24 years and the mean modified Edinburgh score was +90. Emotion-provoking words representing happy, sad, threatened, and neutral emotional valences respectively were chosen by the assessment of 60 normal volunteers using semantic differentiation and Mannequin scales. The activation tasks were designed using modified Posner's paradigm to have 4 blocks of each emotional and control periods, Imaging was conducted on a 1.5T Siemens Vision scanner. Single-shot echoplanar images (TR/TE = 3840/40 ms, flip angle = 90, FOV = 220, matrix = 62 ? 64, slice thickness = 6㎜) were acquired in 20 contiguous slices parallel to the AC_PC line as well as conventional T1-weighted images. Response times were obtained during the scanning, Imaging data were realigned, coregistered, normalized, smoothed, and statistically analyzed in group using SPM-99 software. The results showed that emotional valence of word stimuli produced the effect of attentional engagement. The left superior parietal, inferior frontal, bilateral occipital lobes and cerebellum were main area of modulation of attentional network by emotional words stimuli. The different extent of brain activation induced by different emotion-provoking words were determined.

      • 多樣한 黃芩藥鍼製劑의 安全性 및 效能에 關한 硏究

        김호경,마진열,전원경,윤수영,강은정,주혜정,고병섭 한국한의학연구원 1997 한국한의학연구원논문집 Vol.3 No.1

        In order to detect the safety and effect of various aqua-acupunctures from Scutellariae Radix, the modifications of boiling, filtration and dilution were employed for the manufacture of aqua-acupunctures. We injected 0.2cc of aqua-acupunctures into Joksamri(足三里) of rat, repeatedly. we compared subacute toxicity of them with saline group, distilled water(D.W.) group, acupuncture group and control group. The results were summarized as follows: 1. The groups were all healthy and alive, and there was no special abnormality in physical condition and autopsy. And there were not any toxic symptoms in repeating application of aqua-acupunctures to the rat, including changes of body weight, organ weight, haematological examination and serum biochemical test. 2. There was slight change of body weight in acupuncture group : We could see significance after 3 days (p<0.05) and after 7 days (p<0.001) in body weight loss. After 9 days, all tested groups were suppressed in body weight increment. 3. Result of organ weight: In Palking aqua-acupuncture(D-2 group), saline group and acupuncture group there were some statistical significance. Especially, acupuncture group revealed significant result in liver and spleen than aqua-acupunctures. From this result, we could suggest that the efficacy of acupuncture was preceded herbal medicine. 4. In serum biochemical test, we examined glucose(GLU), triglyceride(TG) and cholesterol(CHOL). In comparison with control group, the diluted 10 times of hwanggum aqua-acupuncture (× 10 group) was recognized significant decrease of glucose, but the diluted 100 times of Hwanggum aqua-acupuncture (× 100 group), D-2 group, saline group were confirmed significant increment. There was not any meaningful change of CHOL in all of tested group, excepting the acupuncture group was exhibited statistically significant decrease(p<0.05). In TG level all tested group except complex injection of standard compound (CPA group) and HG, there were significant value in statistically. The diluted solution was more significant decrease than Hwanggaum aqua-acupuncture(HG). The mutual relationship of components of aqua-acupuncture tended to decrease level of TG, regardless of its concentration. In acupuncture group, we gained some interesting result in meaningful decrease in TG. 5. Haematological examination showed significant increment of gramulocytes(GR) in all tested groups except Hwanggum aqua-acupuncture. And the diluted solutions of HG expressed very high increment of them(p<0.001). The GR and Mean Corpuscular Volume(MCV) of acupuncture group showed statistical significance.

      • KCI등재

        Association Between Gut Regulatory Hormones and Post-operative Weight Loss Following Gastrectomy in Patients With Gastric Cancer

        Hye-Kyung Jung,Chung Hyun Tae,Hye Ah Lee,Ko Eun Lee,Chang Mo Moon,Seong Eun Kim,Ju Young Seoh,Joo-Ho Lee 대한소화기 기능성질환·운동학회 2022 Journal of Neurogastroenterology and Motility (JNM Vol.28 No.3

        Background/AimsPost-operative weight loss in patients with gastric cancer lead to a poor quality of life and long-term survival. This study aims to evaluate the effects of gut regulatory hormones on post-operative weight loss in patients with subtotal gastrectomy for gastric cancer. MethodsThis prospective study was conducted for 12 months post-surgery in 14 controls and 13 gastrectomy patients who underwent subtotal gastrectomy for gastric cancer. Serum plasma ghrelin, glucagon-like peptide-1, gastric inhibitory peptide-1, peptide YY, insulin, and homeostatic model assessment for insulin resistance responses to a standardized test meal were recorded at multiple time points before and after gastrectomy at 4 and 12 months. ResultsThe mean weight difference between the pre-operative state and the 4-month period was significantly reduced to 6.6 kg (P = 0.032), but significant weight reduction was not observed from 4 months to 12 months. The plasma levels of glucagon-like peptide-1, gastric inhibitory peptide-1, and peptide YY were significantly increased 4 months postoperatively compared to the pre-operative state (all P = 0.035); however, pre-operative levels and relative changes over a period of 0-4 months of hormones were not correlated with body weight changes. Only the pre-operative ghrelin at peak had a negative correlation with changes in weight reduction in the 4 months after surgery (ρ = −0.8, P = 0.024). ConclusionsSignificant weight reduction was common after subtotal gastrectomy for gastric cancer with a negative correlation pre-operative plasma ghrelin levels. Incretin hormones are modestly but significantly increased after subtotal gastrectomy; however, these changes did not affect the weight changes.

      • SCOPUSKCI등재

        Serum 25-hydroxyvitamin D as a predictor of hospitalization-free survival in predialysis and dialysis patients with chronic kidney disease: a single-center prospective observational analysis

        ( Eun-jung Ko ),( Bo Hye Kim ),( Hye Yun Jeong ),( Sung Un Soe ),( Dong Ho Yang ),( So-young Lee ) 대한신장학회 2016 Kidney Research and Clinical Practice Vol.35 No.1

        Background: Vitamin D has pleiotropic effects important for the proper functioning of multiple organ systems. We investigated whether serum 25- hydroxyvitamin D [25(OH)D] levels influenced hospitalization-free survival in patients with chronic kidney disease (CKD). Methods: In this prospective study, serum levels of 25(OH)D were measured in 210 patients with CKD in the winter of 2009. Data regarding hospitalizations were collected over the subsequent 3 years. Results: Vitamin D deficiency, as defined by a serum 25(OH)D level below 15 ng/ mL, was observed in 76.7% of the patients. The mean 25(OH)D serum level was 13.6 ± 7.8 ng/mL in predialysis patients (n ¼ 62) and 11.3 ± 6.7 ng/mL in dialysis patients (n ¼ 148). During the follow-up, 107 patients (28 predialysis and 79 dialysis) were hospitalized because of infectious (33.6%) or cardiovascular diseases (23.4%). Predialysis and dialysis groups were divided into 2 subgroups based on the median 25(OH)D serum level. KaplaneMeier analysis revealed that the risk of hospitalization was significantly lower in both predialysis and dialysis patients with above-median serum 25(OH)D levels (log-rank test; P ¼ 0.043 and 0.002, respectively). Multivariate Cox proportional hazards models also demonstrated that the risk of hospitalization was significantly lower for patients with higher serum 25(OH)D levels in both the predialysis (hazard ratio, 0.963; 95% confidence interval, 0.93e0.99) and dialysis groups (hazard ratio, 0.955; 95% confidence interval, 0.91e0.99). Conclusion: A lower serum 25(OH)D level predicted poorer hospitalization-free survival in both predialysis and dialysis CKD patients.

      • SCISCIESCOPUS

        Roles of Aluminum Hydroxide and Monophosphoryl Lipid A Adjuvants in Overcoming CD4<sup>+</sup> T Cell Deficiency To Induce Isotype-Switched IgG Antibody Responses and Protection by T-Dependent Influenza Vaccine

        Ko, Eun-Ju,Lee, Young-Tae,Kim, Ki-Hye,Lee, Youri,Jung, Yu-Jin,Kim, Min-Chul,Lee, Yu-Na,Kang, Taeuk,Kang, Sang-Moo American Association of Immunologists 2017 Journal of Immunology Vol. No.

        <P>Vaccine adjuvant effects in the CD4-deficient condition largely remain unknown. We investigated the roles of combined monophosphoryl lipid A (MPL) and aluminum hydroxide (Alum) adjuvant (MPL+Alum) in inducing immunity after immunization of CD4 knockout (CD4KO) and wild-type (WT) mice with T-dependent influenza vaccine. MPL+ Alum adjuvant mediated IgG isotypeswitched Abs, IgG-secreting cell responses, and protection in CD4KO mice, which were comparable to those in WT mice. In contrast, Alum adjuvant effects were dependent on CD4(+) T cells. MPL+ Alum adjuvant was effective in recruiting monocytes and neutrophils as well as in protecting macrophages from Alum-mediated cell loss at the injection site in CD4KO mice. MPL+Alum appeared to attenuate MPL-induced inflammatory responses in WT mice, likely improving the safety. Additional studies in CD4-depleted WT mice and MHC class II KO mice suggest that MHC class II+ APCs contribute to providing alternative B cell help in the CD4-deficient condition in the context of MPL+Alum-adjuvanted vaccination.</P>

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