위암수술 환자에서의 cp 개발과 cp적용에 따른 질 향상 활동에 관한 연구

임은주,황순휘,박도중,하광일,배현주,김형호 한국의료QA학회 2006 한국의료질향상학회지 Vol.13 No.2

Background : In an era of increasing medical costs, safe reduction in postoperative stay has become a major focus to optimize utilization of healthcare resources. The authors aimed to evaluate the clinical significance of the critical pathway(CP) for gastrectomy patients by implementing standardized postoperative management and electronic medical records. Method : From August 2006 to April 2007, critical pathways were introduced to inpatients and outpatients with gastric cancer. 60 consecutive patients undergoing distal gastrectomy were randomly divided into two groups; 30 CP group(A) and 30 non-CP group(B). Simultaneously, we also retrospectively reviewed the records of 438 patients(C:control group) who were able to be enrolled in CP program. We compared group(A) with (B), (C) in terms of hospital stay, complication rate, use of antibiotics and hospital costs. Patient satisfaction was surveyed by questionnaires. Result : There was no significant demographic difference between group(A) and (B). Of 30 patients in group(A), 5 drop-outs and 14 variances occurred. The mean postoperative hospital stays(Laparoscopy-assisted distal gastrectomy: LADG/Open distal gastrectomy: ODG) were 7.6/10.5 days for the group(A), 8.9/12.7 days for the group(B) and 12.6/14.5 days for the group(C) (p=0.02 in LADG). The total hospital cost of group(A) had a tendency to be less than that of group(B) and the amount of hospital cost per day in group(A) was significantly higher than that in group(B). The usage rates of the first generation antibiotics were 73.33%, 63.33%, and 59.2% in group(A), (B), and (C), respectively. Patients’ satisfaction had a tendency to be higher in the CP group than non-CP group. Conclusion : The mean hospital stay in LADG patients was shortened meaningfully and hospital cost per day was enlarged after introduction of clinical pathway. It is necessary to apply a number of patients to the critical pathway and to make an effort to reduce the variation and drop-out rates.

淨水場內 凝集濟 注入量 豫測을 爲한 自動制御에 關한 硏究

朱恩選,金永道 慶尙大學校生産技術硏究所 1997 生産技術硏究所論文集 Vol.13 No.-

In our country, there are much characteristics of water quality at all seasons. Therefore the optimum coagulant dosing rate and its accurate control are is needed above all. Here, to determine the coagulant dosing rate depending on raw water quality factors, we choose the multilayer perceptron, a sort of neural network method, as a model of automatic process control in the water treatment plant system. Its application to estimate and analyze the coagulant dosing rate has been performed not only by comparative analysis with other system's actual dosing examples and statistical method but also by the improvement of conventional dosing control devices. Its usefulness has been testifed through the above methodical consideration.

가토경골에 식립한 임플란트의 골형성 양상에 관한 방사선학적 고찰

도정주,김은경 단국대학교 치의학연구소 1994 논문집 Vol.6 No.2

The success of osseointegrated dental implants seems to be associated with the enclosure of the implant in a non-pathologic connective tissue or the formation of a direct bone implant interface. The purpose of this study was to examine radiographically the bone formation of several IMZ implants in rabbit's tibia. The results were as follows : 1. Radiographic findings at 3~4 weeks after implantation showed a tendency for loss of the peri-implant radiolucency of lateral aspect. 2. Radiographic findings at 4~6 weeks after implantation showed a tendency for loss of the peri-implant radiolucency of apical aspect. 3. Radiographic findings at 3 weeks after implantation showed an evident tendency for bone apposition along the cervical portion of the implant and complete bony union can be seen at 12 weeks.

악관절의 경두개 방사선사진에서 하악과두위 평가에 관한 연구

도정주,김은경 大韓口腔顎顔面 放射線學會 1992 Imaging Science in Dentistry Vol.22 No.1

Transcranial radiograph is widely used in the diagnosis of craniomandibular disorder because it can be used by the dentist with relative ease in spite of image distortion. But correct information can be obtained only when one know the image change by projection angulation. The author compared the condyle position in the 3 groups of transcranial radiographs(horizontal angulation - 0°, 5°, individualized) with that in the individualized corrected lateral tomogram by objective and subjective evaluation methods. The results were as follows: 1. Among 3 transcranial groups, the condyle position in individualized group showed the highest concordance rate with that in the tomogram group in objective and subjective evaluation methods. 2. Correlation coefficient between individualized transcranial group and tomogram group in objective evaluation method was highest(P≤0.01). 3. Image clarity in individualized transcranial group was worse than that of the other two transcranial groups.

악관절의 경두개 방사선사진에서 하악과두위 평가에 관한 연구

도정주,김은경 단국대학교 치의학연구소 1992 논문집 Vol.4 No.-

Transcranial radiograph is widely used in the diagnosis of craniomandibular disorder because it can be used by the dentist with relative ease in spite of image distortion. But correct information can be obtained only when one know the image change by projection angulation. The author compared the condyle position in the 3 groups of transcranial radiographs(horizontal angulation-0°, 5°, individualized) with that in the individualized corrected lateral tomogram by objective and subjective evaluation methods. The results were as follows : 1. Among 3 transcranial groups, the condyle position in individualized group showed the highest concordance rate with that in the tomogram group in objective and subjective evaluation methods. 2. Correlation coefficient between individualized transcranial group and tomogram group in objective evaluation method was highest(P≤0.01). 3. Image clarity in individualized transcranial group was worse than that of the other two transcranial groups.

실험적 치은염에서 dextranase 함유 구강 세정액의 양치 효과

손은주,김도만,정현주 전남대학교 치의학연구소 2001 구강과학 Vol.13 No.3

A novel glucanhydrolase from a mutant of Lipomyces starkeyi(KSM 22) has been shown effective in hydrolysis of mutan, reduction of mutan formation by Streptococcus mutans and removla per-formed sucrose-dependent adherent microbial film and Lipomyces starkeyi KSM 22 dextranase has been strongly bound to hydroxyapatitie. These in vitro properties of Lipomyces starkeyi KSM 22 dextranase are desirable for its application as a dental plaque control agent. This study was performed to determine oral hygiene benefits and safety of dextranase(Lipomyces starkeyi KSM 22 dextranase)-containing mouthwash in human experimental gingivitis. This 3-week clinical trial was placebo-controlled double-blind design evaluating 1U/㎖ dextranase mouthwash and 0.12% chlorhexidine mouthwash. A total 39 systemically healthy subjects, who had moderate levels of plaque and gingivitis were included. At baseline, 1, 2 and 3 weeks, subjects were scored for plaque(Silness and Lo¨e plaque index and plaque severity index), gingivitis (Lo¨e and Silness gingival index), and at baseline and 3 weeks of experiment, subjects were scored for plaque(Turesky-Quigley-Hein's plaque index and plaque severity index), tooth stain(Area and severity index system by Lang et al). Additionally, oral mucosal examinations were performed and subjects questioned for adverse symptoms. Two weeks after pre-experiment examinations and a professional prophylaxis, the subjects provided with allocated mouthwash and instructed to use 20-ml volumes for 30s twice daily without toothbrushing. All the groups showed significant increase in plaque accumulation since 1 week of experiment. During 3 weeks' period, the dextranase group showed the least increase in plaque accumulation of Silness and Lo¨e plaque index, compared to the chlorhexidine and placebo groups, but chlorhexidine group showed the least increase in plaque accumulation by Turesky-Quingley-Hein's plaque index. As for gingival inflammation, all the groups showed significant increase during 3 weeks of experiment. The groups showed significant increase during 3 weeks of experiment. The dextranase group also showed the least increase in gingival index score, compared to the chlorhexidine as well as the placebo groups. Whereas the tooth stain was increased significantly in the chlorhexidine group, compared to the baseline score and the placebo group since 3 weeks of mouthrinsing. It was significantly increased after 3 weeks in the dextranase group, still less severe than the chlorhexidine group. As for the oral side effect, the dextranase group showed less tongue accumulation, bad taste, compared to the chlorhexidine group. From these results, mouthrinsing with Lipomyces starkeyi KSM 22 dextranase was comparable to 0.12% chlorhexidine mouthwash in inhibition of plaque accumulation and gingival inflammation and local side effects were if anything less frequent and less intense than chlorhexidine in human experimental gingivitis. All data had provided positive evidence for Lipomyces starkeyi KSM 22 dextranase as antiplaque agent and suggested that further development of dextranase formulations for plaque control are warranted.

Isoquinolinium Dichromate에 의한 Alcohol류의 산화반응 속도론과 메카니즘

최선도,박영조,이은주 三陟大學校 産業科學技術硏究所 2003 産業科學技術硏究論文集 Vol.8 No.2

Isoquinolinium dichromate[(C_(9)H_(7)NH)₂Cr₂O_(7)] was synthesized by the reaction of isoquinoline with chromium(VI) trioxide in water. isoquinolinium dichromate[(C_(9)H_(7)NH)₂Cr₂O_(7)] structure was verified by IR. EA and ICP. The oxidation of benzyl alcohol by isoquinolinium dichromate[(C_(9)H_(7)NH)₂Cr₂O_(7)] in carious solvents showed that the reactivity increased with the increase of the dielectric constant s order: cyclohexen < chloroform < acetone < acetonitrile. In the presence of acid, isoquinolinium dichromate [(C_(9)H_(7)NH)₂Cr₂O_(7)] oxidized the substituted benzyl alcohols in N,N-dimethylformamide. The Hammett reaction constant p was -0.69 at 303K. The observed experimental data was used to rationalize the hydride ion transfer in the rate-determining step.

저칼슘식이 생쥐 하악골에서 파골세포의 Tartrate저항성 산성인산분해효소 활성에 대한 세포화학적 연구

박은주,임도선,김현만,고재승 대한구강해부학회 1994 대한구강해부학회지 Vol.18 No.1

The present study was carried out to exanine the morphological changes and TRACP (Tartrate resistant acid phosphatase) activity in the resorption of mandibular bones of mouses resulted, established by low calcium diet. Mice were divided into two groups; one was the calcein group for fluorescent microscopy, the other was the non-calcein group for light and electron microscopy. After calcein injection, mice(ICR) were fed either a low calcium diet (0.01% Ca, 0.75% P) or control diet (0.1% Ca. 0.75% P). Non-calcein group were also fed a low calcium diet or control diet. Mice were sacrificed on 3, 7 and 14 days. For fluorescent microscopy study, fixed undecalcified alveolar bones were embedded in Epon 812, and ground sectioned to study the new bone formation after calcein injection. For the TRACP histochemical study, fixed decalcified alveolar bones were incubated in p-NPP (p-nitrophenyl phosphate) media. For the transmission electron microscopic study, incubated alveolar bone were post fixed in OsO_(4), embedded with Epon 812 for the study of TRACP localzation and activity. The observed results were as follows. 1. Low calcium diet induced bone resorption in buccal and lingual sides of alveolar bone, while the lingual side of alveolar bone was not resorbed in the control group. Bone resorption increased over the period of low calcium diet. 2. The alveolar bone proper of the lingual alveolar bone continued to deposit new bone of the periodontal side even after the low calcium diet. 3. After low calcium diet TRACP activity increased in the cytoplasm of osteoclast, extracellular ruffled border. TRACP activity was also found at the eroded bone matrix after bone resorption, and in the cytoplasm of detached osteoclast. In the immature osteoclast enzyme activity was confined in rER. No enzyme activity was found in the osteoblast.

압축 비디오시퀀스 편집을 위한 동적 매크로블럭 비트할당 MPEG-2 비트율 제어

金柱到,李根泳 성균관대학교 1998 학술회의지원논문목록집 Vol.1998 No.-

본 논문에서는 MPEG-2를 이용한 압축에서 이미 압축되어 있는 영상 시퀀스의 하나 또는 여러개의 GOP(Group of Picture)를 새로운 GOP로 교체하는 편집응용에 필수적인 사용비트량의 정합을 위한 새로운 비트율 제어방법을 제안하였다. 이전영상의 양자화값을 영상전체에 동일하게 적용하여 목표비트에 근접할떄까지 반복적으로 영상을 부호화하고 각 슬라이스의 사용비트량을 기록한다. 영상단위의 양자화값 변화로는 목표비트를 더이상 맞추지 못하므로 기록된 비트량을 이용하여 목표비트에 가장 근접하도록 슬라이스별 양자화값을 조절한 후 최종적으로 각 매크로블럭의 활동도를 참고하여 매크로블럭의 양자화값을 결정하였다. 실제영상에 적용하였을 경우 MPEG-2 Test Model 5에 비해 유사한 PSNR을 보였고 목표비트에 대한 비트에러량은 각 영상당 대략 수 내지 수십비트 이내로 줄임으로써 제안알고리듬의 유효성을 보였다. In this paper, we propose a new Bit-Rate control algorithm based on bit usage matching to substitute encoded GOP(s) for new GOP(s) in MFEG-2 bitstream. It iteratively encodes current picture according to quantization value of previous picture and records bit-usage of each slice until nearly target bits are used. With target bits falling in two output bits, quantization value of slice should be changed to alleviate output bit error. We use recorded bit-usage information to decide which slices should be encoded with one quantization value and others with another. As every macroblock has different activity, we change macroblock quantization value using slice quantization value and activity value. The simulation results demonstrate that the fluctuation of the output bits can be kept within few -several tens of bits while maintaining the quality of the reconstructed pictures at a relatively stable level.

경증 천식 환아에서 비염의 동반이 하기도 호산구 염증에 미치는 영향

한지은,이미현,송도영,강임주 대한 소아알레르기 및 호흡기학회 2004 소아알레르기 및 호흡기학회지 Vol.14 No.2