흰쥐 Kupffer 세포에 대한 Propofol의 작용

박세훈,지대림,성언기,김희선,송인환,박희영,김준수,이덕희,박대팔 대한마취과학회 2002 Korean Journal of Anesthesiology Vol.43 No.4

Background: Propofol has an antioxidant capacity and can be used for ischemia-reperfusion injury of the liver. However, the effects of propofol on the Kupffer cells have not been establisked. Methods: Kupffer cells were isolated and cultured from male Sprague-Dawley rats. The effects of propofol on the Kupffer cells were evaluated by a phagocytosis assay, TNF-α gene expression, and superoxide anion release after administering propofol in different concentrations on the cultured Kuprrer cells. Results: The latex bead phagocytosis by the Kupffer cells was suppressed when the Kupffer cells were exposed to propofol irrespective of concentrations. Higher propofol concentrations decreased the loss of Kupffer cells after latex bead phagocytosis. Propofol induced TNF-α mRNA expression in the Kupffer cells, but the mRNA expression level after 50㎍/ml of propofol decreased. The pattern of TNF-α mRNA expression induced by propofol was different to that induced by LPS: TNF-α mRNA was expressed continuously in the propofol-treated cells until 16 hours after exposure to propofol, whereas the level of TNF-α mRNA expression induced by LPS was evident after 2 hours and was not found thereafter. TNF-α production after propofol treatment was not higher than that of the control. Formazan presipitation did not show any qualitative differences between cells untreated or treated with propofol concentrations of 0.5, 5.0, and 50 ㎍/ml. Conclusions: These results showed that propofol might inhibit Kupffer cells. This suggests that propofol and be used for patients with ischemia-reperfusion injury of the liver. (Korean J Anesthesiol 2002; 43: 475~484)

Park's Vector Pattern의 왜곡률 분석에 의한 BLDC 모터의 권선 고장진단

이대성(Dae-Seong Lee),김준영(Jun-Yong Kim),양철오(Chul-Oh Yang),송명현(Myung-Hyun Song),박규남(Song, Kyu-Nam Park) 대한전기학회 2013 대한전기학회 학술대회 논문집 Vol.2013 No.7

아파트 단위평면의 구성면적변화에 따른 거주후 평가(POE)에 관한 연구

송대호,장승재,박춘근 동아대학교 공과대학 부설 한국자원개발연구소 1995 硏究報告 Vol.19 No.2

The study is presented the model by Stepwise Multiple Regression Analysis, practiced Post Occupancy Evaluation with factor which is to be considered for the change of constituent area after grasping change of constituent area. Apartment unit plan composition is classified in private space, public space, supporting space. The results are as follows: Total constituent area ratio of the existing plan was 39.5 : 40.8 : 19.7 and dwelling consciousness one was 36.4 : 44.0 : 19.6. Compared private space with public space, public area requested increase rather than private area. The Multiple Regression formula between each factor and the constituent area is represented to by HY(Cl)=0.3118+0.52483(C2)+0.28383)C3)+0.10922(C6), but estimate ability of this formula comes into 53.3%.

老朽아파트 再建築에 따른 住居環境評價에 관한 硏究

송대호,박춘근 東亞大學校 建設技術硏究所 1997 硏究論文集 Vol.21 No.1

This study is related to the rational improvement plan according to the dwelling environment estimation factors when deteriorated apartment complexes is reconstructed. The results is follows : (1) External environment in this deteriorated apartment complexes is proved generally very bad condition with physical worn out condition of the building. Especially, it is proved that parking lot and green space, dust facilities, etc are lacked commonly. (2) When we synthesize the recognition degree to the dwelling environment. It made an analysis that dwellers have been estimate the most factors at the green space and physical facilities or deterioration of the building and EV-stairway, dwellers' demands are changing to apartment complexes environment from the investment worth concept at house basis in the past. (3) As reconstructed, in preference on improvement of deteriorated apartment complex, It values middle story type above ratio of capacity increase in higher story type and higher density type. And Unit residence has to connect a green tract of land and open space. Also convenient facilities has to expand. Finally, there is limit that estimate basic factors about dwelling environment established inclusively in this study, unsatisfying with exactly the solve of cause in the factors. So, it is required that the study (which can receive variety changing factors) is continuing for accumulating this estimation data.

老朽아파트 再建築에 따른 住居環境評價에 관한 硏究

송대호,박춘근 동아대학교 건설기술연구소 1997 硏究報告 Vol.21 No.1

This study is related to the rational improvement plan according to the dwelling environment estimation factors when detoriorated apartment complexes is reconstructed. The results is follows: (1) External environment in this detoriorated apartment complexes is proved generally very bad condition with physical wornout condition of the building. Especially, it is proved that parking lot and green space, dust facilities, etc are lacked commonly. (2) When we synthesize the recognition degree to the dwelling environment. it made an analysis that dwellers have been estimate the most factors at the green space and physical facilities or deterioration of the building and EV·stairway, dwellers' demands are changing to apartment complexes environment from the investment worth concept at house basis in the past. (3) As reconstructed, In preference on improvement of deteriorated apartment complex, It values middle story type above ratio of capacity increase in higher story type and higher density type. And Unit residence has to connect a green tract of land and open space. Also Convenient facilities has to expand. Finally, there is limit that estimate basic factors about dwelling environment established inclusively in this study, unsatisfying with exactly the solve of cause in the factors. So, it is required that the study (which can receive variety changing factors) is continuing for Oaccumulating this estimation data.

濟州道 食品 수요豫測을 위한 調査硏究

朴吉淳,宋大鎭 제주대학교 1974 논문집 Vol.6 No.-

In this survey we tried to find out how habit, income, and the price of foodstuffs affected the eating habits of the people in Je Ju Do so that the most economical and efficient plan of foodstuffs distribution could be carried out. The results are as follows : 1) The rate of consumption of several foodstuffs (banana, dried persimon, canned fish, canned meat etc. ) decreased markedly when their price doubled. But the rate of consumption of other foodstuffs (soy sauce, bean paste, hot bean paste etc. ) only decreased slightly when their price doubled. 2) when we asked what foodstuffs the people would eat if their food budget was increased 50%, the highest percentage responded that they would eat more rice cakes. Others mentioned rice, barley, wheat flaur, broad, apple, mandarin oranges, pears, eggs, milk, etc. But the increase of these foodstuffs was only slight. The consumption of wine was reduced. 3) The frequency of consumption for some foodstuffs was small while for others it was large.

사비의 교정에 있어서 내시경의 이용

박대환,김태모,이재욱,송철홍,한동길,안기영 大韓成形外科學會 1998 Archives of Plastic Surgery Vol.25 No.1

Owing to the complexity of the deviated structures and the septal deformities accompanying the external nasal deformities, the complete correction of the deviated nose is regarded as a difficult one. The approach to the nasal bone and osteotomy in classic corrective rhinoplasty is almost blind technique, where the results depends on the feeling by surgeon's hand. To overcome these drawback, endoscopic-assisted corrective rhinoplasty and septoplasty performed for 8 cases of deviated nose between January 1996 and May 1997. Average follow-up period was 10 months. All patients were evaluated by symmetrical nasal pyramid, recurrence of the bony deflection and septal deviation. The postoperative courses were satisfactory in most of cases with few complications. It appears that endoscopic control during corrective rhinoplasty and septoplasty is a big step toward obtaining better results in bony and cartilage resection with extreme precision under monitor control and magnification. This technique is not an open approach but permits one to see more of the nasal skeleton and bony septum what is causing deformity, and the immediate effect of the corrective measures used. The use of endoscope in corrective rhinoplasty will provide expanded field of vision, direct manipulation of lesions, and better aesthetic an6 functional results.

내시경을 이용한 관골궁골절 정복술

박대환,이재욱,장경수,송철홍,한동길,안기영 大韓成形外科學會 1998 Archives of Plastic Surgery Vol.25 No.1

Although the zygomatic arch can be employed as a key landmark to the accurate alignment of a displaced zygoma fracture, it has been traditionally avoided because of the need for a bicoronal incision. Exposure of the zygomatic arch by means of the conventional bicoronal incision has several possible disadvantages, including an increased risk of blood loss, alopecia, loss of sensation posterior to the incision, and traction palsy of the facial nerve. Endoscopic-assisted exposure of a zygomatic arch can largely obviate the disadvantages of a bicoronal incision and yield this site accessible to reduction and internal fixation in the routine treatment of displaced zygoma fractures. 9 cases of endoscope-assisted open reduction of zygomatic arch fracture and 3 cases of internal fixation of a moderately displaced zygoma fracture are presented. To accomplish this technique, a rigid 4 mm, 30 degree down-angled endoscope, trocar and cannula, endoscopic forehead lift instrument were used. The postoperative courses were satisfactory with few complications. The use of endoscope in the treatment of zygoma reduction provided an expanded field of vision, direct manipulation of lesions, minimal postoperative scar. In particular, exposure and fixation of the zygomatic arch were performed without the need for a bicoronal incision.

디자인 발상에 있어서 Morphing System의 유효성에 관한 기초연구

송홍권,박대순 한국디자인과학학회 1999 디자인과학연구 Vol.2 No.-

오늘날 디자인은 도구를 만들고 환경을 쾌적하게 만드는데 국한되는 것이 아니다. 이것을 만들어내는 디자이너는 물론 판매를 하는 기업에까지도 사회적, 도덕적 책임을 요구한다. 그러므로 디자인 작업은 고도의 과학적이고 혁신적인 연구와 끊임없는 창조 작업의 연속이어야 하고, 인간사회 전반에서 요청 되고있는 다변화된 욕구 충족 요구를 신속히 반영할 수 있는 과학적 접근 방법을 필요로 하게되었다. 따라서, 본 연구의 목적은 디자인 개발과정에 있어서 새로운 형태접근인 Morphing System 울 이응한 정량분석 방법론에 있다. 본 연구는 다음과 같은 가설을 전제로 하였다. 첫째: 우리가 영화의 특수 효과에서나 볼 수 있었던 몰핑(Morphing)이 디자인 발상과정에 있어서 새로운 형태 창조나 소비자의 새로운 Trend분석에 활용할 수 있는 기초자료가 될 수 있을 것이다. 둘째: 몰핑(Morphing)의 이미지 변환기법을 이용하면 두 이미지(Image) 또는 오브젝트(Object) 간에 새로운 형태를 만들어내므로 디자인적인 접근이 가능하다. 따라서, 디자이너가 새로운 형태에 접근함에 있어 보다 신속하고 다양한 디자인형태를 제시할 수 있으므로 최소의 시간을 투자하여 최대의결과를 유출할 수 있을 것이다. 이러한 형태 접근을 위한 Morphing System은 2개의 프로토타입(Prototype)만을 가지고도 다양한 형태를 유추할 수 있다. 디자이너가 아이디어창출을 하는데 있어서 많은 유효성을 가져다준다. 따라서, 본 논문의 목적은 Morphing System을기반으로 한 컴퓨터 지원 시스템 개발에 필요한 기초연구에 있다. These days design cannot only confine to make tools and better environmental conditions, Not only designers but corporations that manufacture there products need social and moral responsibilities about them. Design process could be scientific Inventive studios and continuous creative working which needs scientific approaches based on various social, cultural conditions. This study proposes more effective and scientific analyses on Morphing system for design process. It could bea basic hypothesis to analysis trend of new forms and consumers. Also, this is based on making a new shape between two images or objects. Therefore, designer can flow out the best products with minimum economi-cal time. This accessing to Morphing system will locate in prototype original point and develop the concept on the same core level without wasting time to create the same shape. consequently, this study is based on the development of computer supporting system with a morphing system base.

미세혈관 협심증 환자의 임상상 및 지표에 관한 연구

박상호,온영근,김현정,이태훈,길효욱,김현건,박수진,송해정,한대희,방덕원,신원용,이내희,김성구,권영주 순천향의학연구소 2003 Journal of Soonchunhyang Medical Science Vol.9 No.1

Background : Microvascular angina or syndrom X is heterogenous and encompasses different pathogenetic entities. Several studies suggest that microvascular angina have good prognosis and occurs predominantly in postmenopausal women. Lipoprotein (a), total cholesterol, LDL-cholesterol, HDL-cholesterol, triglyceride, homocystein, CRP and fibrinogen are the independent risk factor of acute coronary syndrome and are the chief underlying cause of atherosclerosis. We investigated clinical characteristics and markers in patients with microvascular angina. Methods : We studies 23 patients diagnosed with microvascular angina and 16 control group with negative treadmill exercise test and no significant coronary angiogram. We investigated clinical characteristics in patients group and evaluated symptom during a follow-up period of 4.2± 2.5 month. Exercise time in treadmill exercise test was compared between patients and control group. We assessed the level of markers, such as lipoprotein (a), total cholesterol, LDL-cholesterol, HDL-cholesterol, triglyceride, homocystein, CRP and ESR in two groups. Results : There is no difference in age between two groups. Patients group had a tendency to increase in female, hypertension, DM, and smoking history, but there was no statistical significance difference. Exercise duration time was significantly decreased in patients with microvascular angina (p<0,05). Serum lipoprotein (a), total cholesterol, LDL-cholesterol, HDL-cholestrol, Triglyceride, ESR, Fibrinogen and Homocystein value were no significant difference between microvascular angina and control group. Only CRP was significantly high in patients with microvascular angina (p<0.05). Conclusion : There was no statistical significance difference in age, sex, hypertension, DM and smoking history between two groups but patients group had a tendency to increase the prevalence in hypertension, DM and smoking history, female. Also, Symptom improvement and disappearance in follow-up was presented in 11 patients of 19(57.9%). Exercise tolerance was worse in patients group than control group. CRP value was significantly higher in patients group than control group. There was no statistical significance difference in lipoprotein (a), total cholesterol, LDL-cholesterol, HDL-cholesterol, triglyceride, homocystein, ESR and Fibrinogen between two groups.