분지각이 작고 일시 개화성이 우수한 숙근 안개초 ‘드림송’ 육성

정동춘(Dong-Chun Cheong),최창학(Chang-Hak Choi),송영주(Young-Ju Song),김정만(Jeong-Man Kim),이진재(Jin-Je Lee) 한국원예학회 2014 원예과학기술지 Vol.32 No.4

‘Bristol Fairy’ 유래의 결실되는 아조변이체인 ‘Gyp99’의 실생계통으로 밝은 백색 겹꽃에 소화가 큰 ‘Gyp06-11’로부터 2008년 특성이 우수한 ‘Gyp08-2’ 계통을 선발하여 2009-2010년 2년 동안 특성평가 및 특성검정을 통해 ‘Dream Song’을 육성하였다. ‘Dream Song’의 초형은 직립형이고, 잎 모양은 피침형, 소화는 꽃잎수가 많고 암술이 2개인 백색겹꽃으로 꽃잎은 도란형, 꽃잎 끝 모양은 약간 둥근형, 꽃받침 모양은 컵형인 ‘Dream Song’ 고유의 특성을 가진다. 또한 소화의 일시개화성이 우수하고 절화수명이 매우 길며, 분지각이 작고 흰가루병에 강하고 총체벌레와 잎굴파리 등 충해에도 강해 재배적 가치가 높은 특성을 가진다. 준고냉지 여름절화 작형에서 ‘Dream Song’ 개화는 ‘Bristol Fairy’보다 17일 늦고 절간장과 화경장이 길었으며, 측지 분화가 많고 줄기가 굵었다. 또한 소화가 크고 야간 기온 22℃, 7일 이상의 고온조건에서도 기형화 발생이 없었다. ‘Dream Song’ is a cultivar of Gypsophila paniculata developed by the Jeollabuk-do Agricultural Research & Extension Services in 2010 for cut-flower production. This hybrid was bred from 121 seedlings collected from an open-pollinated population of ‘Gyp06-11’. It has novel morphological characteristics of upright plant type, lanceolate leaves, double florets with a few bright white-colored petals of obovate shape, truncate petal tips, and cup-shaped calyces. Furthermore ‘Dream Song’ has desirable cultivation characteristics including narrow branching angle, and moderate resistance to powdery mildew, thrips and leaf miners. Moreover it produces more primary branches, and longer internodes and flower stalks than reference cultivar ‘Bristol Fairy’ during summer cultivation in a subalpine area (500 m over the sea level). Flowering in ‘Dream Song’ is delayed by about 17 days as compared to ‘Bristol Fairy’. ‘Dream Song’ produces normal flowers with 2 pistils and an average of 10.4 stamens, with fewer malformed flowers than ‘Bristol Fairy’.

접합부의 비선형 거동을 고려한 강뼈대 구조물의 고등해석과 최적설계

최세휴,박문호,송재호,임청권,Choi, Se Hyu,Park, Moon Ho,Song, Jae Ho,Lim, Cheong Kweon 한국강구조학회 2003 韓國鋼構造學會 論文集 Vol.15 No.6

The advanced analysis and optimal design of semi-rigid frame were presented. Advanced analysis can predict the combined nonlinear effects of connection, geometry, and material on the behavior and strength of semi-rigid frames. The Kishi-Chen power model was used to describe the nonlinear behavior of semi-rigid connections. Geometric nonlinearity was determined using stability functions. On the other hand, material nonlinearity was determined using the Column Research Council (CRC) tangent modulus and parabolic function. The direct search method proposed by Choi and Kim was used as optimization technique. The member with the largest unit value evaluated using the LRFD interaction equation was replaced one by one with an adjacent larger member selected from the database. The objective function was assumed as the weight of steel frame, with the constraint functions accounting for load-carrying capacities, deflections. inter-story drifts, and ductility requirement. Member sizes determined by the proposed method were compared with those derived using the conventional LRFD method. 본 논문에서는 접합부의 비선형을 고려한 강뼈대 구조물의 고등해석과 최적설계를 수행하였다. 고등해석은 접합부의 비선형, 기하학적 비선형 및 재료적 비선형을 고려한다. 접합부의 비선형은 Kishi와 Chen이 제안한 3가지 매개변수를 가지는 파워모델을 사용하여 고려하였다. 기하학적 비선형은 안정함수를 사용하여 고려하였으며, 재료적 비선형은 CRC 접선 탄성계수와 포물선 함수를 사용함으로서 고려하였다. 최적화 기법으로는 Choi와 Kim이 제안한 직접탐색법을 사용하였다. 직접탐색법은 LRFD의 상관방정식으로 계산된 값중에서 최대값을 가지는 부재의 크기를 단계별로 증가시키는 방법이다. 목적함수는 구조물의 중량을 사용하였으며, 제약조건식은 구조시스템의 하중-저항능력, 처짐, 층간 수평변위 및 연성요구 조건을 고려하였다. 제안된 방법에 의한 설계결과를 LRFD방법과 비교하였다.

Crystallization of High Purity Ammonium Meta - Tungstate for Production of Ultrapure Tungsten Metal

Choi, Cheong Song,Kim, Jun Hyung,Lee, Choul Ho 한국화학공학회 2000 Korean Journal of Chemical Engineering Vol.17 No.6

The growth mechanism of Ammonium Meta-Tungstate (AMT) crystal was interpreted as two-step model. Growth rates of AMT crystals were measured in a fluidized bed crystallizer. The effects of temperature, supersaturation and crystal size on the crystal growth were investigated. The contribution of the diffusion step increased with the increase of temperature, crystal size and supersaturation. The nucleation kinetics from measurements on the width of the metastable region of Ammonium Meta-Tungstate (AMT) was also evaluated. The crystal size distribution from a programmed cooling crystallization system was predicted by the numerical simulation of a mathematical model using the kinetics of nucleation and crystal growth. It was also observed that the shape of AMT crystals was changed during the growth period.

Efficacy of the Arbekacin and Teicoplanin Combination on Glycopeptide Intermediate Staphylococcus aureus in a Rabbit Model of Endocarditis

Cho, Cheong Ho,Choi, Jun Yong,Han, Sang Hoon,Lee, Han Sung,Choi, Suk Hoon,Chin, Bum Sik,Choi, Hee Kyoung,Jeoung, Su Jin,Kim, Myung Soo,Kim, Chang Oh,Kim, Chang Ki,Yong, Dongeun,Song, Young Goo,Lee, Ky 대한감염학회 2008 감염과 화학요법 Vol.40 No.2

목적 : 동물 모델을 이용하여 GISA에 의한 심내막염에서 teicoplain과 arbekacin 병용 요법의 치료 효과를 알아보고자 하였다. 재료 및 방법 : 토끼 심내막염 모델을 이용하여 GISA 에 의한 심내막염에서 teicoplanin과 arbekacin 병용 요법의 효과를 단독 요법의 효과와 비교하였다. GISA 균주는 Mu50 균주를 사용하였고, 기존 문헌과 동일한 방법으로 토끼를 이용하여 동맥판 심내막염 모델을 사용하였다. 항생제 치료는 균을 주사한지 20시간 이후에 시작하였다. Teicoplanin은 40 mg/kg를 1회 근육 주사한 후에 20 mg/kg의 용량을 12시간 마다 4일간 투여하였다. Arbekadn은 5 mg/kg를 12시간 마다 4일간 근육 주사하였다. 마지막 항균제 투여 20시간 이후에 토끼 대동맥판의 증식(vegetation)을 채취하였다. 항균제를 투여하지 않은 대조군, teicoplanin 단독 치료군, arbekacin 단독 치료군, teicoplanin과 arbekacin 병용치료 군간의 증식의 무게(gram) 당 log_10)CFU의 차이를 비교하였다. 결과 : Teicoulanin과 arbekacin 병용 치료군에서 teicoplanin단독 치료군, 혹은 arbekacin 단독 치료군에 비해 증식의 무게(gram)당 log_10)CFU 값이 유의하게 낮았다(P<0.05). 결론 : 동물 모델에서 GISA에 의한 심내막염에 대한 teicoplanin과 arbekacin 병용 치료의 효과가 teicoplanin이나 arbekacin 단독 치료에 비해 우월하였다. Background : There have been no reports to evaluate the usefulness of combination therapy with glycopeptide and arbekacin in endocarditis by in vivo model. Materials and Methods : We investigated the efficacy of the arbekacin and teicoplanin combination on glycopeptide intermediate Staphylococcus aureus (GISA) in rabbit model of endocardits. GISA Mu50 strain was used for the experiment. The rabbit model of aortic valve endocarditis as described previously was used. Treatment was started 20h later inoculation with teicoplanin alone (at 20 mg/kg of body weight intramuscularly every 12 hours for 4 days after loading dose of 40 mg/kg of body weight intramuscularly), arbekacin alone (5 mg/kg of body weight intramuscularly every 12h for 4 days), or teicoplanin plus arbekacin. Results : The results of therapy for experimental endocarditis due to Mu50 showed that teicoplanin and arbekacin combination was more effective than the administration of both drugs alone in reducing the log_10)CFU/g of aortic vegetation (P<0.05). Conclusion : The combination of teicoplanin and arbekacin was more effective against GISA (Mu50) than both drugs alone in vivo endocarditis model.

간섭계 기반 분광편광타원계를 이용한 박막두께 측정

김청송(Cheong Song Kim),최인호(InHo Choi),헤리저데헌거흐 사이드(Saeid Kheiryzadehkhanghah),최석현(Sukhyun Choi),황국현(Gukhyeon Hwang),김대석(DaeSuk Kim) 대한기계학회 2020 대한기계학회 춘추학술대회 Vol.2020 No.8

최근 국내 반도체 DRAM 및 NAND flash 메모리 제조 기술 고도화로 인하여 wafer 상단에 수 나노 스케일 수준의 박막증착 및 패턴 제작이 이루어지고 있으며, 이에 공정라인에서 제작되는 시편을 검사/계측하기 위한 기술에 대한 필요성이 요구되는 추세이다. 반도체 생산 제조 공정라인의 검사/계측 기술로 활용되는 ellipsometry 기술은 산란을 이용한 비파괴성 광학적 측정 기술로, 시편에 의해 변화된 편광정보(Ψ, △)를 획득하고, 이를 분석하여 제작 시편의 물성 및 박막 두께, 나노 패턴의 3D 형상을 계측하는 기술이다. 현 반도체 산업계에서 제작되는 wafer의 균일도는 기업의 수율과 관계하므로 측정속도에 대한 솔루션의 필요성이 크게 증대되고 있는 상황이며, 이에 기존 ellipsometry 기술이 지닌 기계적 메커니즘 및 전기 변조 장치 등의 구동부로 인한 초 단위 이상의 측정속도 제한 문제를 극복하기 위하여 본 연구팀은 2016년 마하젠더 scheme의 분광편광타원계측 기술을 제안한바 있다. 이는 간섭편광변조모듈로부터 발생된 분광편광간섭신호를 시스템 알고리즘을 통해 분광편광위상정보(△)를 20Hz 이상 고속으로 획득 가능하다. 본 연구팀은 최근 간섭편광변조모듈을 일체형 마이켈슨 간섭계로 구성함에 따라, 측정 반복능을 ±1˚ 수준의 외란에 강인성을 지닌 시스템으로 성능을 크게 개선하였다. 아래 figure(a)의 Blue, Red line은 각각 reference(bare wafer), SiO2 30nm를 제안된 시스템으로 획득된 간섭spectrum이고, figure(b)의 Blue, red line은 각각 간섭계 기반 분광편광타원계와 상용 ellipsometer를 이용하여 측정된 분광편광위상정보(△)이다. SiO2 30nm 측정결과를 통해 간섭계 기반 분광편광타원계는 측정 반복능 뿐만 아니라, 측정에 사용된 전체파장에 대해서 상용장비 수준의 높은 정확도가 확보됨을 검증하였다. [그림 본문 참조]

Biochemistry , Molecular Biology : Floral Nectary - specific Gene NTR1 Encodes a Jasmonic Acid Carboxyl Methyltransferase

(Yang Do Choi,(Jong Joo Cheong,(Ing Yu Hwang,(Jong Seob Lee,(Sang Ik Song,(Min Kyun Kim,(Song Yion Yeu,(Choon Kyun Jung,(Yeon Jong Koo,(Jong Tae Song,(Hak Soo Seo 한국응용생명화학회 2001 Journal of Applied Biological Chemistry (J. Appl. Vol.44 No.3

NTR1 gene of Brassica campestris L.ssp.perkinensis encodes a floral nectary-specific methyltransferase. In this study, the NTRl cDNA was expressed in E. coli to examine the enzymatic characteristics of the protein product. The GST-NTR1 fusion protein was p

치료 경험이 없는 HIV 감염자에서의 항바이러스제 일차내성 분석 : 한국HIV/AIDS 코호트 연구

송준영,이진수,정혜원,최희정,이진서,이재갑,엄중식,정희진,정문현,김우주 대한감염학회 2009 감염과 화학요법 Vol.41 No.4

Primary anti-retroviral resistance is considered one of the major problems of HIV treatment. Contrary to reports from western countries, prior Korean studies have reported a relatively low primary resistance rate (less than 5%). Based on Korean HIV/AIDS cohort data, we estimated the primary resistance rate among treatment-na¨ıve HIVinfected patients. According to the results, the primary resistance rate was higher (8.8%) than reported previously in Korean studies. However, the major PI mutation was not found.

해안 저질토중 중금속과 유기물질의 오염에 관한 연구

최형일,정경훈,김인수,송영일 조선대학교 환경연구소 1994 環境公害硏究 Vol.11 No.-

The contents of heavy metals and total organics in bottom mud of the Mokpo marine have been investigated. This area was divided into three regions; Daebul, Mokpo, and Sanjung, and sampling sites region were selected by eight sites. Marine bottom mud mere investigated three times during this study and twenty-four samples are taken from eight sampling sites. Analytical species were Cdmium, Copper, Lead, zinc, Arsenic and total organics. The Heavy metals were analyzed by atomic absorption spectrophotometry, also total organics were analyzed by gravimetry. The major resurts of the studies were as follows: 1. The contents of the heavy metals and total organics in marine bottom mud were Cadium 0.272 mg/kg, Copper 3.384 mg/kg, Lead 9.647 mg/kg, zinc 10.031 mg/kg, Arsenic 0.636 mg/kg, Total organics 5.99 wt%. 2. The Zinc was higher than any other heavy metals in the marine bottom mud. The mean contents of heavy metals in Sanjung region was the lowest. 3. Lead and Arsenic species were influenced by the pollutants influxed from Youngsan River, and Cadium and Copper were less than it's contents of the natural soils. 4. The total organics in the marine bottom mud was exceedingly increased as the contrasted with the small particle size of the marine bottom mud, and the corelation coefficients between heavy metals and total organics were high. (0.5<r<0.8)

전국 10개 종합병원 중환자실 환자의 직장내 Vancomycin-resistant Enterococci(VRE) 보균율, 보균의 위험요인 및 유전적 다양성 조사

정희진,송준영,엄중식,김우주,최선주,최정현,이혁,정문현,이광미,신동현,손보라,최종성,우흥정,권정아,이경원,최강원,박승철 대한감염학회 2002 감염 Vol.34 No.5

Disease burden of hospitalized community-acquired pneumonia in South Korea : Analysis based on age and underlying medical conditions

Choi, Min Joo,Song, Joon Young,Noh, Ji Yun,Yoon, Jin Gu,Lee, Saem Na,Heo, Jung Yeon,Yoon, Jae Won,Jo, Yu Mi,Cheong, Hee Jin,Kim, Woo Joo Williams & Wilkins Co 2017 Medicine Vol.96 No.44

<▼1><P>Supplemental Digital Content is available in the text</P></▼1><▼2><P><B>Abstract</B></P><P>Pneumonia is a leading cause of hospitalization and mortality worldwide. Despite recognition of the importance of community-acquired pneumonia (CAP) in adults, limited epidemiologic information is available in South Korea. This study aimed to evaluate the disease burden of hospitalized CAP in adults aged ≥19 years and its epidemiologic trend using Health Insurance and Review Assessment (HIRA) data.</P><P>This is a retrospective study using the HIRA database from year 2009 to 2013. We estimated the incidence rate and direct medical cost of hospitalized CAP in adults aged ≥19 years in South Korea. These were further analyzed with respect to age and underlying medical conditions.</P><P>During 2009 to 2013, 1216,916 hospitalizations were recorded. On average, the annual age-adjusted incidence rate of hospitalized CAP was 626 per 100,000 persons, with the rate increasing with age. When stratified by age- and risk groups, elderly people ≥75 years showed the highest incidence rate of hospitalized CAP over 5-year study periods. With respect to the risk groups based on underlying medical conditions, incidence rate ratios were 2.04 to 5.86 for the high-risk group versus the low-risk group and 1.28 to 5.49 for the moderate-risk group versus the low-risk group. Overall, mean direct medical cost for hospitalized CAP was 1851 USD per capita during the 5-year period: 1263 USD in the low-risk group, 2353 USD in the moderate-risk group, and 2841 USD in the high-risk group.</P><P>This study shows that the incidence and medical cost of hospitalized CAP were consistently high over the 5-year study period. In particular, elderly people and adults with underlying medical conditions were at increased risk for hospitalized CAP.</P></▼2>