Hypophosphatasia 환아의 치료 증례

최병제,최형준,이제호,김기덕,박수정 大韓小兒齒科學會 1998 大韓小兒齒科學會誌 Vol.25 No.3

1. Hypophosphatasia 는 골조직 및 치아조직의 비정상적인 석회화를 나타내는 대사장애로, 특징적구강내 소견 인 우치의 조기탈락 양상으로 치과에서 조기진단이 가능하다. 2. 본 증례에서 상악궁 확장을 동반한 의치 제작으로 심미적, 기능적으로 양호한 결과를 얻었으며, 영구치열기 까지 장기적 관찰 및 치료가 필요할 것으로 사료된다. hypophosphatasia is a rare metabolic disorder which manifests characteristics such as abnormal mineralization of bone and dental tissues, diminished serum and tissue alkline phosphatase, and increased urinary secretion of PEA. It ingerited as an autosomal recessive or dominant trait and occurs in all races. In general, hypophosphatasia can be classified in 4 subtypes which are the perinatal, infantile, childhood, adult type depending upon the age at presentation and severity. In young children with Hypophosphatasia the long bones show irregular defects, and the skull showes poor calcification. In older children with premature closure of the skull sutures there may ve multiple lucent area called gyral or convolutional markings, described as resimbling beaten copper, presumably resulting from increased intracranial pressure,Examination of the jaws reveals a generalized lucency of the maxilla and mandible, the cortical bone and lamina dura are thin, and the alveolar bone may be deficient. Clinical features of Hypophosphatasia imclude premature loss of deciduous teeth, especially incisors, hypoplasia of aplasia of root cementum, enamel hypoplasia, irregular calcification of dentin, large pulp chamber, and resorption of marginal alveolar bone and roots. Our report involves a patient with a chief complaint of early loss of both Mx. and Mn. deciduous ncisors. after conducting a through clinical and radiographic examination this patient was referred to pediatrics under the suspicion of hypophosphatasia, the diagnosis proved to be correct and successful results were accomplished through a denture made to improve esthetics and function.

우리나라 산촌정주권의 유형과 연계개발모형

강병수,오덕성,최영일 忠南大學校 地域開發硏究所 1998 地域開發論叢 Vol.10 No.-

In order to develop natural resources of mountain village regardless of renewable or nonrenewable resources, it is one of very important approaches to connect between county center and residents' settlement in mountain village in terms of both equity and efficiency. There is no study on the linking mechanism between county center and residents' settlement in mountain village in terms of types of mountain villages including resource oriented development, tourist and resort types. This study focused on the improvement of social infrastructure for the vitalization of the mountain village development, and the comparison of three types of mountain villages. Finally, the study suggested the connection model between the county center and the residents' settlement in Korean mountain villages according to each three type.

북한이탈주민의 외상 후 스트레스 장애와 자연살해세포 활성

김병창,정성훈,임효덕,최종혁,전정희,전양환 大韓神經精神醫學會 2008 신경정신의학 Vol.47 No.5

Objectives : The objective of this study was to evaluate an association between posttraumatic stress disorder (PTSD) and altered immunity m North Korean defectors who were more likely to develop medical conditions and other stress-related psychiatric disorders. Methods : Twenty-four North Korean defectors with PTSD and twenty-two controls without PTSD were recruited from the resettlement and training center for North Korean defectors in South Korea. Peripheral T lymphocyte subsets, natural killer(NK) cells, NK cell activity and plasma hormones (ACTH and cortisol) were obtained from all subjects. We also applied the Hamilton Rating Scale for Depression (HAM-D) and Hamilton Rating Scale for Anxiety (HAM-A) for all subjects. Results : We found NK cell activity was relatively lower than number of NK cells in North Korean defectors with PTSD. Subjects with PTSD had higher HAM-D and HAM-A scores than controls. However, there were no statistical differences in ACTH. cortisol, CD3, CD4, CD8, CD4/CD8 ratio, CD19 and CD56 between the two groups. Conclusion : These findings suggest North Korean defectors with PTSD show higher levels of depression, anxiety and impaired or weak immune function in NK cells.

平價切下에 依한 우리나라 國際收支 改善方案

崔炳德 건국대학교 상경대학 1986 商經論叢 Vol.- No.21

Factors That Affect Health Professionals’ Preparation of Advanced Directives in Korea

Byung Deog Hwang,Ryoung Choi,Jae Woo Park 보안공학연구지원센터 2015 International Journal of Bio-Science and Bio-Techn Vol.7 No.3

A survey was conducted among medical professionals including hospices, nurses, and administrative personnel who often heard the concept of AD and had many chances to observe related medical occasions to grasp their attitudes toward the preparation of AD. The logistic regression analysis was conducted to examine whether the objects agreed upon preparation of the form of AD and its effect on decisions about meaningless life-prolonging treatment. Factors affecting decisions about the preparation of AD included religion and education in the case of hospices, income and education in the case of nurses, and marriage, income, working experience, legislative institutionalization, and education in the case of administrative personnel. Factors affecting the decision of rejecting meaningless life-prolonging treatment (life-prolonging equipment) included working experience and the one who would make out the form in the case of hospices, income, and working experience in the case of nurses, and income and working experience in the case of administrative personnels. Factors affecting the decision of rejecting meaningless life-prolonging treatment (artificial nutrient supply) included working experience and the one who would make the form in the case of hospices, working experience in the case of nurses, and income and working experience in the case of administrative personnel. It turned out that there was a difference in the recognition of AD and meaningless life-prolonging treatment among medical professionals. Hence, it is vital to deliver accurate information on Advanced Directives, reduce differences among the members, and form a social consensus so that patients' right of autonomous choice and dignity can be guaranteed.

피혁제조 산업장의 작업환경실태에 관한 조사 연구

조윤숙,문덕환,김필자,안진홍,김영기,손병철,김대환,이창희,김휘동,이채언 인제대학교 백병원 2002 仁濟醫學 Vol.23 No.5

Objective: This study was aimed to prepare the fundamental data on the exposure level of physical agents and hazardous materials originated from in the leather manufacturing industry to identify potential factors capable of causing worker's health problems. Method and Materials: Subjects related to this study consist of 50 leather manufacturing factories located in Busan area from Feb. 1. 2000 to Dec. 31. 2001 Results: Potentially hazardous chemical substances and physical agents originated from the leather manufacturing industry were noise, dust, chromium, eight organic chemical substances, and three specific chemical substances, buffing and setting process were exceeded Threshold Limit Values-Time Weighted Average(85 dBA) recommended in American Conference of Governmental Industrial Hygienists. The exposure level for chromium in dyeing process was higher than that of other processes. Organic solvents capable of causing health problems were originated from the painting and coating process. Exposure level for chromium and organic solvents were not exceeded in each permissible exposure level established in Korea. Conclusion: As a result, a wide variety of hazardous materials related to occupation were originated from the leather manufacturing industry. The author suggests that more positive work environment management program should be required to identify factors relative to occupational health problems.

요로감염 선별검사에서 dipstick 요분석의 진단적 가치

최순덕,조한준,김기혁,조동영,유병연 대한가정의학회 2000 Korean Journal of Family Medicine Vol.21 No.6

Effects of Moxibustion to Zusanli(ST36) on Alteration of Natural Killer Cell Activity in Rats

Choi, Gi Soon,Han, Jae Bok,Park, Joon Ha,Oh, Sang Deog,Lee, Gi Seog,Bae, Hyun Su,Jung, Sung Ki,Cho, Young Wuk,Ahn, Hyun Jong,Min, Byung Il WHO COLLABORATING CENTRE FOR TRADITIONAL MEDICINE 2004 東西醫學硏究所 論文集 Vol.2004 No.-

Moxibustion is one of the major healing techniques in Oriental medicine. It has been widely used in many diseases such as rheumatoid arthritis, Hashimoto disease, breech presentation, etc. However, till now, effects of moxibustion on natural killer (NK) cell activity and relations between sympathetic nerve system (SNS) and the immune alteration induced by moxibustion wert not well studied. This study was designed to evaluate effects of moxibustion on NK cell activity and the Intervention of SNS in the alteration of NK cell activity induced by moxibustion. Splenic NK cell cytotoxicity was measured in a standard 4-hour ^(51)Cr release assay. We measured the NK cell cytotoxicity after moxibustion stimulation for 1, 3, 5 and 7 days, and also measured the NK cell cytotoxicity after 3 and 7 days burn stimulation with similar temperature. Interleukin (IL)-2, -4 and interferon (INF)-γ in serum were measured by rat IL-2, -4 and INF-γ ELISA test kit. To evaluate the effects of sympathectomy on alteration of NK cell cytotoxicity, 6-hydroxydopamine (6-OHDA: 50 mg/kg) was used. We showed that NK cell activity of moxibustion stimulation group incrcased at the 3rd day, and declined at the 7th day in comparison with that of the control group. In thc moxibustion stimulation group, NK cell activity was significantly higher than the sham group at the 3rd day. On the contrary, in the burn stimulation group, NK cell activity was significantly higher than that of the sham groups at 3rd and 7th days. INF-γ level after 3 days in the moxibustion stimulation group was significantly higher than that of the sham group. IL-2 Ievel among groups were not different. IL-4 was not detected in serum with this method. Sympathectomy abolished the NK cell activity alteration induced by moxibustion. The results suggest that moxibustion modulates NK cell activity, along with INF-γ, and SNS is mediating these effects.

Impacts of initial temperature and cylindrical obstacles on the dispersing flammable limits of accidental methane releases in an LNG bunkering terminal

Choi, Byung Chul,Park, Kweon-Ha,Doh, Deog-Hee Elsevier 2018 Journal of hazardous materials Vol.355 No.-

<P><B>Abstract</B></P> <P>This paper presents a numerical study on the dispersing flammable limits with respect to the initial methane releases at <I>T</I> <SUB>CH4,0</SUB> = −50 and −150 °C in the crosswind of ambient air according to the arrangement of (a) No Tank, (b) Tank I, (c) Tank II, and (d) Tank I and II on the ground. To provide a better physical insight on the dispersion behaviors of the methane releases, the spatial distributions of the quasi-averaged methane concentration and flow fields were mainly analyzed using 3-D large eddy simulations. Consequently, the results of both the parameters can be summarized in that the vortex characteristics of the rotating direction and vorticity generated by the interactions not only between the crosswind and cylindrical obstacles but also between the crosswind and releasing methane flows played important roles in determining the dispersing flammable limits depending on the mixing characteristics.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Dispersing flammable limits of accidental methane releases were investigated. </LI> <LI> The lean flammable limits (LFLs) were compared for <I>T</I> <SUB>CH4,0</SUB> = −50 and −150 °C. </LI> <LI> The effect of cylindrical obstacles on the gas dispersion was compared. </LI> <LI> The LFLs distributions were analyzed with the vortical flow structure. </LI> </UL> </P>

Factors Influencing Suicide Dimensions in the Elderly

Byung Deog Hwang,Jae Woo Park,Ryoung Choi 보안공학연구지원센터 2016 International Journal of Bio-Science and Bio-Techn Vol.8 No.1

This correlational study provides basic data concerning important factors influencing suicide dimensions among the elderly by determining the characteristics of health behavior among the elderly and analyzing their association with suicide. This study used primitive data from “The 6th Korea National Health and Nutrition Examination Survey, the 1st year (2013)” conducted by the Ministry of Health and Welfare and Centers for Disease Control and Prevention. A total of 2,458 study subjects aged over 55 participated in this study. Statistical analysis of the study data was performed using SPSS 21.0. Frequency analysis was performed on the sociodemographic characteristics of the subjects, and a Chi-squared test was used to examine the correlations between the study variables in relation to the sociodemographic characteristics of the subjects. Logistic regression analysis was performed to determine the odds ratio for the correlation analysis. The results of this study were as follows. First, variations in suicide dimension factors according to elderly classifications and the presence of chronic diseases showed statistically significant differences in relation to the presence of economic activities, the presence of a spouse, and overall health behavior factors. Second, of all the main factors that affect suicide dimensions, the presence of a spouse, subjective health status, restriction of physical activities, and stress level were shown to have statistically significant effects. To reduce the suicide dimensions of the elderly, it will be necessary to help them escape chronic diseases, increase their physical functions with regular physical activities and health status maintenance, and manage their depression, which is the first stage of the suicide dimension. This can only be accomplished by developing social programs based not only on individual efforts but also on an accurate understanding of the elderly population.