뇌혈관질환 환자의 후유증의 개선에 대한 Propentofylline(HWA 285)의 임상 연구

최영빈,박정욱,한시령,양동원,나정호,김범생 최신의학사 1994 最新醫學 Vol.37 No.6

자궁내막암의 임상병리학적 고찰

한병수(BS Han),이학희(HH Lee),송준(J Song),박찬용(CY Park) 대한산부인과학회 1992 Obstetrics & Gynecology Science Vol.35 No.4

Significant advance in our knowledge of endometrial cancer have occured in the past decade. The incidence of the disease has risen in most western, industrial countries, and better understanding of the pathologic subtypes has evolved the relationship between exogenous estrogen use and endometrial cancer has been well documented. We have studied clinico-pathologic subtypes has evolved the relationship between exogenous estrogen use and endometrial cancer has been well documented. We have studied clinico-pathological correlation of endometrial carcinoma in 20 patients from July, 1975 to June, 1989 at Department of Obstetrics and Gynecology in National Medical Center. The mean age of endometrial cancer was 52 and mean parity was 2.3 Fifteen cases (75%) were postmenopausal, 4 cases (20%) were menopausal and 1 case (5%) was premenopausal. Pathologic subtypes were adenocarcinoma (60%), adenoacanthoma (20%), papillary adenocarcinoma (10%) and adenosquamous cell carcinoma (10%) in order of frequency. Abnormal vaginal bleeding was encountered in 90%, commonly postmenopausal, 75% lower abdominal pain in 15% and vaginal discharge in 10%, respectively. Risk factors were hypertension (20%), infertility (20%), obesity (15%), estrogen use (10%), diabetes millitus (5%) and hyperlipidemia (5%). Associated pelvic pathologies were myoma uteri (25%), adenomyosis (20%), endometrial hyperplasia (15%) and ovarian cyst(10%), respectively. A great number of patient (90%) was stage Ib. Concordance rate between clinical and surgical stage was 80%. Thirteen cases (65%) were treated by TAH and BSO, 4 cases (20%) by TAH, BSO with selective lymphadenectomy, 3 cases (15%) by TAH, BSO with radiation.

자발성 두개강내 출혈에 대한 임상적 분석 : from Jan. - '80 to Sep. - '87

한대희,오창완,이선호,최길수,심보성 대한신경외과학회 1989 Journal of Korean neurosurgical society Vol.18 No.7-12

The authors analyzed 619 patients with spontaneous intracranial hemorrhage which had been diagnosed by brain CT scan. The following results were obtained; 1) The causes, in descending order of frequency, were aneurysm, hypertension, arteriovenous malformation, tumor, Moyamoya disease, blood dyscrasia and infarction. 2) The peak incidence age was in the 5th and 6th decades, but arteriovenous malformation cases showed peak incidence in the 3rd decade. 3) The peak incidence season was spring, but arteriovenous malformation cases showed even distribution around the year. 4) Of the 619 cases, 445 cases(71.9%) were treated operatively. Of them, 321 cases(51.9%) were treated radically, removing the cause of hemorrhage. 5) Regarding the frequent site of hemorrhage, SAH was present in 94% of aneurysm cases, ICH in 99% of hypertension cases and 85% of arteriovenous malformation cases, and SDH in 80% of blood dyscraesia cases. 6) Aneurysm cases showed best prognosis and hypertension cases showed most serious prognosis. 7) Cases with intraventricular hemorrhage showed poor prognosis.

뇌수막종에 대한 임상적 고찰

한종우,김정훈,이선호,김현집,한대희,심보성,최길수 대한신경외과학회 1989 Journal of Korean neurosurgical society Vol.18 No.5

The authors analyzed the surgical treated meningioma patients admitted to department of neurosurgery of Seoul National University Hospital between January, 1978 and December, 1987. The following results were obtained: 1) Meningioma was the most common in the 5th decade (46 cases, 37.7%) and the male to female ratio was 1:2.1 2) The pathologic types were meningothelial type (94 case, 77.0%), transitional type, fibroblastic type and angioblastic type in order of frequency. 3) Convexity represented the single most common site of tumor (36 cases, 29.5%), followed by the parasagittal-falx, sphenoid wing, and cerebellopontine angle (CPA) in order of frequency. 4) The most common initial presentation was ⅡCP sings and the mean duration of symptom was 22.5 months. 5) The most common CT finding was high density in PCT and strong homogeneous enhancement in ECT. Hypervascularity was seen in 83 cases (70.3%) on the angiography. 6) The total removal was done in 73.8% of patients and the postoperative mortality rate was 4.1%. 7) At the time of the analysis, 15 cases(12.3%) had shown evidence of recurrence, and the mean duration of recurrence was 3.18 months. 8) The follow up result was excellent in 75 cases(61.5%), good in 28 cases(23.0%), fair in 8 cases(6.6%), and poor in 6 cases(4.9%) and dead in 5 cases(4.1%).

자간전증 산모에서 증가된 혈장 호모시스테인의 위험인자로서의 임상적 유용성 연구

신봉식(BS Shin),김범영(BY Kim),최익준(IJ Choi),장우섭(WS Jang),조현구(HG Jo),이교원(KW Lee),송혜섭(HS Song),한종설(JS Han),김성도(SD Kim) 대한산부인과학회 1998 Obstetrics & Gynecology Science Vol.41 No.10

Objective: This study was designed to determine whether homocyst(e)ine is elevated in nulliparous pregnant women with preeclampsia, and to evaluate a clinical usefulness of elevated plasma homocyst(e)ine with preeclampsia as a risk factor. Methods: Of 40 nulliparous pregnant women studied from October, 1997 to March, 1998, 20 had preeclampsia (severe: 9, mild: 11; 13 early onset preeclampsia of 20) and 20 were normal pregnant controls. We measured plasma homocyst(e)ine levels by high performance liquid chromatography , and folic acid and vitamin B12 concentrations by radioimmunoassay at the time of their delivery. Results: Mean (standard deviation) plasma homocyst(e)ine levels in the two groups, 20 nulliparous women with preeclampsia and 13 nulliparous women with early onset preeclampsia, were significantly higher than in the 20 nulliparous women without preeclampsia, respectively (12.61±3.06 versus 6.63±1.72 μmol/L, P<0.05; 12.71±3.41 versus 6.63±1.72 μmol/L, P<0.05). Folic acid and vitamin B12 concentrations were not significantly different between two groups, respectively (folic acid, 6.86±2.96 versus 8.17±3.26 nmol/L; vitamin B12, 237.8±73.1 versus 277.4±68.9 pmol/L). Mean (standard deviation) plasma homocyst(e)ine levels were not significantly different between severe and mild preeclampsia(13.79±3.23 versus 11.65±2.68 μmol/L). Conclusion: Homocyst(e)ine levels are elevated in nulliparous pregnant women with preeclamsia at the time of their delivery and might be useful to predict the preeclampsia as a risk factor. Further studies are required to determine what role homocyst(e)ine may play in the etiology of preeclampsia, and to investigate how to prevent preeclampsia.

주상변압기 열적 특성 향상을 위한 복합절연 시스템 적용

이병성(BS Lee),송일근(IK Song),이재봉(JB Lee),김동명(DM Kim),한상옥(SO Han) 대한전기학회 2002 대한전기학회 학술대회 논문집 Vol.2002 No.7

Determination of Anaerobic Capacity - Reliability and Validity of Sprint Running Tests

( Corinna Wawer ),( Oliver Heine ),( Hans-georg Predel ),( Md Da-sol Park ),( Bs Woo-hwi Yang ) 한국운동생리학회(구 한국운동과학회) 2020 운동과학 Vol.29 No.2

PURPOSE: A number of physiological diagnostics were developed. However, the timeline-related diagnostics of maximal anaerobic glycolytic capacity remain unclear. The objective of this study was to evaluate the reliability and validity of a sprint running test to assess the anaerobic capacity. METHODS: The study was divided into three parts. Sixty-one male (24±4 years, 181.0±4.3 cm; 78.5±5.9 kg) and twelve female (25±3 years, 167.0±0.6 cm, 60.4±5.7 kg) sports students participated in this study. Twenty-five subjects (13 males, 24±2 years, 181.0±0.5 cm, 78.5±5.9 kg; 12 females, 25±3 years, 167.0±0.6 cm, 60.4±5.7 kg) performed incremental step tests at running track and several linear sprints on a running track (LSRT) with different time durations (8, 10, 12, and 14 seconds)(part I) on different days. Twenty-five male subjects (24±3 years, 180.7±6.7 cm, 84.6±8.8 kg) conducted a 10 or 12 second sprint running on a non-motorized treadmill (NMT)(part II). In part III, twenty-three male subjects (24±2 years, 181.4±5.8 cm, 74.5±7.4 kg) ran a 10 second LSRT and NMT on consecutive days. Capillary blood samplings were taken before (Lac_r) and after the sprint running for ten minutes at one minute intervals to find out maximal lactate concentration after exercise and to calculate the maximum lactate production rate (LPRmax). RESULTS: For all parts reliability for LPR_max was proven (Part I: 8 seconds: ICC: r=.89; 10 seconds: ICC: r=.82; 12 seconds: ICC: r=.92; 14 seconds: r=.84, respectively; Part II: 10 seconds: ICC: r=.76; 12 seconds: ICC: r=.79). To analyze validity for LPR_max, Part III was conducted and proven valid (ICC: r=.96, p=.074). CONCLUSIONS: We demonstrate that LSRT and NMT reliably determine anaerobic capacity and can be used as a valid tool for physiological performance diagnostics.

뇌혈관조영술 소견상 잠재성인 뇌혈관기형

왕규창,조병규,한대희,이선호,김현집,지제근,심보성,최길수 대한신경외과학회 1989 Journal of Korean neurosurgical society Vol.18 No.7-12

본 교실에서는 뇌혈관조영술 소견상 나타나지 않은 잠재성 뇌혈관기형 17예를 경험하여 이들에서 특징적인 임상 소견을 관찰할 수 있었으며 특히 MRI가 본 질환의 진단과 관리에 있어 큰 도움이 되었기에 문헌고찰과 함께 이를 보고하는 바이다. Authors report 17 cases of angiographically occult vascular malformation of the brain experienced from July 1978 to February 1989. In 11 cases the diagnosis was confirmed by the operative and pathological findings and in the other 6 cases the clinical course and the radiological findings suggested the diagnosis. All the cases had the evidences of hemorrhage. Five of those had episodes of repeated hemorrhage. The characteristic findings of magnetic resonance imaging improved the sensitivity and specificity of diagnosis. Case summary and illustrative cases were presented with the review of literature.

항-HLA-B62+B75 항체에 의한 신생아 동종면역성 혈소판감소증 1례

이진석,박범수,박현진,선용한,송은영,박명희,한규섭 大韓輸血學會 2002 大韓輸血學會誌 Vol.13 No.2

조산 및 만삭임신에서의 Shake Test

이학희(HH Lee),한병수(BS Han),박홍식(HS Park),조성진(SJ Cho) 대한산부인과학회 1992 Obstetrics & Gynecology Science Vol.35 No.11

Foam test is a rapid, simple, econological test which has been devised to determine whether surfactant is present in amniotic fluid. the test depends on the ability of the pulmonary surfactant to generate stable foam in the presence of ethanol. We analysed each 23 and 25 sample of amniotic fluid in preterm and term by foam test. The results were as follows; 1. The result were 3 negative, 2 intermediate and 28 positive in preterm and all positive in term. 2. Infants of 43 pregnant women with positive test were free of respiratory distress. 3. 3 negative and 2 intermediate test were false negative. 4. There was no correlation between false negative and Apgar score of 1 minute.