결함 포용 정적 Shuffle-Exchange 네트워크

최홍인 한국정보과학회 2003 정보과학회논문지 : 시스템 및 이론 Vol.30 No.4

정적 shuffle-exchange 네트워크는 여러 응용 알고리듬에 적용되고 현재 많이 사용되는 다중 단계 네트워크에 비해 적은 하드웨어를 사용하는 등 많은 장점이 있으나 아직까지 어떤 병렬처리 컴퓨터에도 채택된 없었다. 그 이유 중에 하나는 결함 내성 기능이 없었기 때문이다.본 논문에서는 다중 결함 포용 정적 shuffle-exchange network를 소개한다. 본 논문에서 제시되는 결함 포용 정적 shuffle-exchange 네트워크는 k 결함을 제어하기 위해서 최소 2k의 추가 처리 요소들과 각 처리 요소들은 최대 4k의 추가 shuffle 링크를 필요로 한다. k 결함 내성을 가진 정적 shuffle-exchange 네트워크를m A static shuffle-exchange network is not only useful for several parallel applications but also use less hardware than the popular multi-stage network or hypercube. Even though it has a lot of advantages, it has never been used in any implemented parallel machine. One of the reasons is there has not been any techniques to make the network fault-tolerant.In this paper multiple fault-tolerant static shuffle-exchange networks are presented. In order to recover from k

Quantatitive analysis on the chemotaxis of Chlamydomonas reinhardtii towards bicarbonate using agarose-gel-based microfluidic device

최홍일,김영환,심상준 한국공업화학회 2016 한국공업화학회 연구논문 초록집 Vol.2016 No.0

Microalgae have garnered considerable attention for their ability to produce various products utilizing CO2. Despite the importance, various biological phenomena are still unknown. Here, we examined the chemotaxis of C. reinhardtii towards HCO3(-) using an agarose-based microfluidic device. The availability of the device was tested by previously studied chemicals: NH4Cl and CoCl2 are chemoattractants, while NaCl is neutral. We observed the chemotaxis of C. reinhardtii towards HCO3(-) for the first time and found the concentration for the strongest response. In circadian clock-related chemotaxis assay, the chemotaxis peaked in the middle of the night while the response was quite low during the daytime. Furthermore, we verified several factors influencing on CCM caused significant change in the chemotactic behavior. This study would provide a fundamental of HCO3(-)-induced chemotaxis and may promote the understanding of inorganic carbon utilization.

2P-380 Quantitation of the Chemotactic Response of a Green Microalga, Chlamydomonas reinhardtii, to Bicarbonate Using a Novel Microfluidic Device

최홍일,심상준 한국공업화학회 2017 한국공업화학회 연구논문 초록집 Vol.2017 No.1

Microalgae have garnered considerable attention for their ability to produce various products utilizing CO₂. Despite the importance, various biological phenomena are still unknown. Here, we examined the chemotaxis of C. reinhardtii towards HCO₃^- using an agarose-based microfluidic device. The availability of the device was tested by previously studied chemicals: NH₄Cl and CoCl₂ are chemoattractants, while NaCl is neutral. We observed the chemotaxis of C. reinhardtii towards HCO₃^- for the first time and found the concentration for the strongest response. In circadian clock-related chemotaxis assay, the chemotaxis peaked in the middle of the night while the response was quite low during the daytime. Furthermore, we verified several factors influencing on CCM caused significant change in the chemotactic behavior. This study would provide a fundamental of HCO₃^--induced chemotaxis and may promote the understanding of inorganic carbon utilization.

Venlafaxine 투여로 회복을 보인 공황장애와 범불안장애가 병발한 환자의 치료 1예

최홍,윤세창,Choi, Hong,Yoon, Se-Chang 대한불안의학회 2006 대한불안의학회지 Vol.2 No.1

Panic disorder is a relatively common psychiatric illness (life time prevalence 3.5%), and it is known that 91% of patients with panic disorder have at least one other psychiatric disorder. And patients with panic disorder, who have coexisting generalized anxiety disorder, tend to have more severe symptoms and less favorable outcome and respond less well to psychological and pharmacologic treatment. The authors report a 51-year old male who was previously diagnosed as panic disorder in the out-patient clinic, showed poor response to antipanic treatment. However, he showed great improvement after he was treated for panic disorder and comorbid generalized anxiety disorder. This case report showed that more effort to identify comorbid conditions is needed in panic disorder patients and the effectiveness of venlafaxine in the treatment of panic disorder with generalized anxiety disorder.

Genetic Algorithm을 적용한 Fuzzy DEA에 관한 연구

최홍,손소영 한국경영과학회 2000 한국경영과학회 학술대회논문집 Vol.- No.1

DEA has been effectively applied to various areas which need the evaluation of relative efficiency. We propose a DEA model based on fuzzy LP combined with Genetic Algorithm in order to consider uncertain synergy effects due to M&A of exiting organization. We apply the suggested approach to forecasting the efficiency of merged academic departments in a university in Korea. We expect that our approach can be utilized to effectively realign existing departments.

정신분열병환자의 우울증상 및 인지장애와 BDNF Val66Met 유전형과의 연관성

최홍,이정구,김민철,정성수,이찬홍,박성우,김영훈 대한정신약물학회 2007 대한정신약물학회지 Vol.18 No.3

Objective: We investigated the association of serum brain-derived neurotrophic factor (BDNF) levels and its genotypic distribution with depressive and cognitive symptoms in patients with schizophrenia. Methods: The subjects were 207 patients who met the DSM-IV criteria for schizophrenia and 100 normal subjects. We evaluated psychotic, depressive, and cognitive symptoms using the Brief Psychiatric Rating Scale, 17 Hamilton's Rating Scale for Depression, and the Korean version-Mini Mental Status Examination in schizophrenic patients. The serum level of BDNF was analyzed with ELISA and the genotypic distribution of BDNF was examined in all subjects. Results: No statistically significant differences were detected in genotype or serum level of BDNF between the patients with schizophrenia and normal subjects, between depressed and nondepressed patients, or between the patients with and without cognitive impairments. The frequency of Met alleles was high in the depressive schizophrenic patients with cognitive impairments (P < 0.05). Conclusion: Met alleles are associated with depression in schizophrenic patients with cognitive impairments, but serum BDNF concentration is not related to the presence of depression or cognitive impairments. 본 연구에서 저자들은 정신분열병 환자의 우울증상 및 K-MSE점수와 BDNF 유전형 및 혈청 농도와의 연관성에 대해 알아보고, 환자와 대조군에서 BDNF 유전형과 혈청 BDNF의 농도의 상관관계를 알아보고자 하였다. DSM-Ⅳ 진단기준에 부합하는 207명의 정신분열병 환자군과 10명의 정상 대조군을 대상으로 BPRS, 17 항목 HAM-D 및 K-MSE를 사용해서 정신병적 증상과 우울증상 및 인지기능을 평가하고 BDNF Val6Met유전형을 분석하였다. 정신분열병 환자군과 정상 대조군에서 BDNF 유전형 분포와 혈청 농도 사이에는 유의한 차이가 없었다. 우울 증상을 동반한 정신분열병 환자군과 동반하지 않은 환자군 사이에도 BDNF 유전형 분포와 혈청 BDNF의 농도는 유의한 차이가 없었고, K- MMSE 점수가 25점이상인 환자군과 K- MMSE점수가 25점 이하인 환자군 사이에서도 BDNF 유전형 분포와 혈청 BDNF의 농도는 유의한 차이는 없었다. 그러나 K- MMSE 점수가 25점 이하인 환자군에서 우울증상이 있는 군이 그렇지 않은 군보다 Met 대립유전자 빈도가 높았다(p<0.05). 본 연구의 결과에 의하면 정신분열병 환자의 우울증상과 인지기능저하 각각에 따른 BDNF Val6Met 세 가지 유전형(V/V, V/M, M/M) 분포와 대립유전자(V, M)의 빈도는 연관성이 보이지 않았다. 또한 만성 정신분열병 환자의 우울증상과 인지기능저하에 따른 혈청 BDNF 농도에는 차이가 없었다. 그러나 K-MSE점수가 25점 이하인 정신분열병 환자들 중에서 우울증상이 있는 군이 없는 군보다 Met 대립유전자 빈도가 더 높았다.

청소년쉼터 근무환경이 서비스 질에 미치는 매개경로 효과분석

최홍일 ( Hong Il Choi ),이상균 ( Sang Gyun Lee ) 가톨릭대학교 사회복지연구소 2011 사회복지리뷰 Vol.16 No.-

본 연구는 청소년쉼터의 근무환경이 직무만족과 직무스트레스를 매개변인으로 하여 서비스 질에 미치는 영향에 관하여 알아보고자 한 연구이다. 이를 위해 전국 45개단기 청소년쉼터에 근무하는 145명 실무자들을 대상으로 근무환경과 직무만족도, 직무스트레스, 서비스질의 수준에 대해서 자기보고식 척도 설문지를 사용하여 전수조사 하였다. 분석은 매개효과 검증을 위한 경로분석과 매개효과의 유의성 검증으로 진행되었다. 연구결과 청소년쉼터 근무환경은 직무스트레스와 직무만족을 통해 서비스 질에 이르는 경로를 완전매개 하는 것으로 나타났다. 다시 말해 청소년쉼터 근무환경이 서비스 질에 영향을 미침에 있어서 직원들이 체감하는 직무스트레스와 직무만족이 중요한 연결고리로 작용 한다는 것이다. 이를 통하여 청소년쉼터에서 제공하는 서비스 질의 개선을 위해서는 청소년쉼터 실무자들이 근무하는 환경의 수준 향상을 통하여 실무자들의 직무스트레스를 낮추고 직무에 대한 만족도를 높여야 함 알 수 있다. This study was conducted in order to investigate whether the direct path from youth shelter`s environment to service quality level was in any way mediated by job satisfaction and job stress. The participants in this study were 145 practitioners from 45 short-term youth shelters. This study was using self-report questionnaires including working environment, job satisfaction, job stress, and service quality level. Data were analyzed to identify the factors using path analysis for mediation effect. The result revealed that youth shelter`s environment significantly predicted service quality level through job satisfaction and job stress as a mediating factor. The member of staffs who are conscious of job stress and job satisfaction is connection with youth shelter work environment that is effect on quality of service. Implication of this study is to provide higher quality of work environment to practitioners in order to improve the level of service quality by reducing practitioner`s job stress and increase job satisfaction.

DEA를 이용한 공대 학과별 효율성 비교 연구

최홍,손소영,Choi Hong,Sohn So-Young 한국공학교육학회 1999 공학교육연구 Vol.2 No.1

본 연구의 주목적은 현재 연세대학교 공과대학 내에 속해 있는 14개 학과를 대상으로 DEA를 이용한 다양한 각도의 효율성 평가를 실시하여 각 학과들의 운영상의 상태와 문제점을 규명하고 이에 대한 개선책을 제시하는데 있다. 더 나아가 학부제라는 대학 내의 조직적인 변화에 대해 제도 도입의 효율성을 극대화시키기 위해서, 여러 가지 가상 시나리오에 따른 각 학부 및 학과의 효율성의 추이를 살펴보고 이를 통해 최적의 학부 형태를 선택하는데 필요한 초석을 다지고자 한다. DEA (Data Envelopment Analysis) is applied to evaluate performance of 14 academic departments at the college of engineering in Yonsei University. Various input and output variables are used to identify operational inefficiency and to suggest some strategic improvement. Additionally, we analyze organizational changes of some existing departments to be merged under several scenarios. Our study results are expected to effectively provide constructive directions for reconfiguration of academic departments.

Quantitative analysis of chemotactic response towards bicarbonate and CO₂ fixation efficiency in Chlamydomonas reinhardtii

최홍일,노혜진,심상준 한국공업화학회 2019 한국공업화학회 연구논문 초록집 Vol.2019 No.0

Microalgae utilize carbon dioxide (CO₂) and bicarbonate (HCO3-) as carbon sources through CO₂ concentrating mechanism. In this study, we demonstrated the relationship between the extent of chemotactic response towards HCO3- and CO₂ fixation efficiency of the wild-type and mutants of Chlamydomonas reinhardtii CC125 in a microfluidic device. The movement of the microalgae was quantitatively evaluated by the degree of skewness and asymmetry of distribution. The results showed that the well-growing mutants had a tendency towards higher HCO3- concentration. In addition, the correlations between the chemotactic response and both the growth (△OD) and the photosynthetic efficiency (Y(II)) showed high linearities. This result implies that chemotaxis can be used as a strategy for high-throughput screening to identify microalgal strains with high CO₂ fixation efficiency.

센서 네트워크를 이용한 실내 흡연감지 모니터링 시스템

최홍의(HongEui Choi),김철(Chul Kim),유효상(HyuSang Yoo),이상호(Sangho Lee),안병구(Beongku An) 한국통신학회 2015 한국통신학회 학술대회논문집 Vol.2015 No.11