『오륜전비언해(伍倫全備諺解)』역주(譯註) (12)

柳在元 ( Jae Won Yoo ),鄭蓮實 ( Yon Sil Jeong ),趙娟廷 ( Youn Jung Cho ) 한국외국어대학교 중국연구소 2012 中國硏究 Vol.55 No.-

Sayeokwon(司譯院), the national institute of foreign languages, was established for the purpose of good diplomatic relations with China in Chosun dynasty. It made lots of teaching materials for teaching Chinese, one of which was Wulunquanbeiyanjie(伍倫全備諺解). It is usually said that "Logeoldae(老乞大) & Paktongsa(朴通事): L&P" were the most widely used textbook, but we have the historical records that Wulunquanbeiyanjie was regarded as an important material by the officers of Sayeokwon and was also used as a teaching material in the mid 1500s. The value of Wulunquanbeiyanjie is as high as that of a series of L&P. The following three properties of Wulunquanbeiyanjie as a textbook can be referred. It fits with the purpose of teaching spoken Chinese in that period. It shows the adequacy and precision in phonetic notation. It contains various factors concerning Chinese language in its contents. Wulunquanbeiyanjie has just been used as a studying material of early modern Korean mainly by Korean linguists. It was not noticeable in studying Chinese so far. This book has translated the Chinese text in terms of Chinese linguistic, which not only could provide the basic material for syntax and vocabulary studying but also could be used in studying of modern spoken Chinese.

《오륜전비언해(五倫全備諺解)》역주(譯註)(3)

구준,유재원(역) ( Jae Won Yoo ),정연실(역) ( Yon Sil Jeong ),조연정(역) ( Youn Jung Cho ) 한국외국어대학교 외국학종합연구센타 중국연구소 2007 中國硏究 Vol.39 No.-

만성 위염전

최지호(Ji Ho Choi),문찬일(Chan Il Moon),김주현(Ju Hyun Kim),김필운(Pill Woon Kim),이승원(Seung Won Lee),정연실(Yon Sil Jung),양동경(Dong Kyung Yang),지현규(Hyeon Gyoo Ji),박현철(Hyun Cheul Park) 대한소화기학회 1997 대한소화기학회지 Vol.30 No.4

Gastric volvulus or torsion is a rare disease which is caused by a rotation of the stomach above 180. Clinical featres are abrupt abdominal pain at the acute state and indigestion at the chronic state associated with a closed loop obstruction. The diagnosis is confirmed by barium study and endoscopy with clinical features. Acute gastric volvulus is a surgical emergency but chronic volvulus in a 75 year. old man who complained of indigestion and early satiety. The stomach volvulus was diagnosed by gastrofiberscope and upper gastrointestinal barium study and it was treated by conservertive management. (Korean J Gastroenterol 1997; 30:537-540)

만성 위염전 1예

양동경,김필운,문찬일,이승원,정연실,지현규,최지호,김주현,박현철 大韓消化器病學會 1997 大韓消化器病學會誌 Vol.30 No.4

방사성요드 치료를 받은 그레이브스병 환자에서 예후와 연관된 인자

박혜영,강문호,김홍규,이성광,정연실,공희상 대한내분비학회 1999 Endocrinology and metabolism Vol.14 No.4

Background: Prediction of therapeutic response to radioactive iodine (RAI) in Graves disease is poorly understood. Although thyrotropin binding inhibitor immunoglobulin (TBII) level is a strong index for relapse after antithyroid drug treatment, conflicting results are described regarding its prognostic significance in Graves disease treated with RAI. This study is to evaluate possible prognostic factors including TBII wbich affect the outcome of RAI therapy in Graves disease. Methods: Two hundred and one patients with Graves disease who were followed for over 12 months after RAI treatment were studied retrospectively. The subjects were divided into hypothyroid, euthyroid and hyperthyroid groups, based on the thyroid function evaluated at 12 months after RAI therapy. We evaluated the association of clinical parameters including patients age, goiter size, degree of hyperthyroidism and TBII index with outcome of RAI treatment. Results: In Graves disease, response rate to RAI was 70.1% (hypothyroid 22.4% and euthyroid 47.7%) until 12th month. The mean age of hypothyroid group was 40±11 years, significantly older than that other groups (euthyroid: 33±12, hyperthyroid: 35±13, p$lt;0.05). Initial level of thyroid function, duration of antithyroid drug treatment prior to RAI, goiter size and dosage of RAI were not significantly different between the groups. There were 61 patients who had both TBII tests before and after RAI. Twelve had negative TBII and 49 had positive TBII before RAI admini-stration. The rate of unremitted hyperthyroidism after RAI therapy was significantly lower in patients with negative TBII than in those with positive TBII prior to RAI treatment( 0% versus 46.9%, p$lt;0.05). Conclusion: Graves patients with positive TBII prior to RAI therapy were associated with lower therapeutic response to RAI than those with negatve TBII. And old age was associated with the development of early hypothyroidism after RAI therapy. These results suggest these factors be also considered in the treatment of Graves diseaseth RAI (J Kor Soc Endocrinol 14:679-687, 1999).

항갑상선제 투여 중 발생한 간 손상

이기영,이윤정,홍순홍,정성권,이화은,서찬종,정연실,이성광,김홍규,박혜영,강문호 대한내분비학회 2000 Endocrinology and metabolism Vol.15 No.4·5

갑상선 유두암 환자에서 뇌전이 2 예

이기영,박혜영,강문호,김홍규,김종호,이정구,정연실 대한내분비학회 1999 Endocrinology and metabolism Vol.14 No.4

Papillary carcinoma, the commonest thyroid malignancy, has an indolent clinical course and carries a good prognosis. Metastasis usually occurs to regional lymph nodes, including cervical and upper mediastinal nodes. Distant metastasis is uncommon, lung and bone being the commonest sites. Brain metastasis from papillary thyroid cancer is rare, with a frequency of less than 1% in several reported series and an extremely poor prognosis. The first case was a 74-year-old female patient with papillary cancer who took total thyroidectomy followed by 131I therapy 1 month later. Two days after 131I therapy, she developed headache, vomiting and left hemiplegia. Brain MRI and 131I whole body scan showed solitary brain metastasis in right parietal lobe. After a few weeks her condition improved enough to maintain her usual daily activity despite mild motor weakness. The second one, a 64-year-old female patient presented with headache and vomiting. Two years previously, she had taken total thyroidectomy and 131I ablation therapy after diagnosis of thyroid papillary cancer. Eight months before, she had undergone radical neck dissection because of relapse in cervical lymph nodes. Brain MRI revealed multple metastatic lesions including cerebellum. This patient did not report for follow-up after 2 months of discharge(J Kor Soc Endocrinol 14:745-751, 1999). 131

항갑상선제 투여 중 발생한 간 손상

이기영,이윤정,박혜영,강문호,김홍규,이성광,정연실,홍순홍,정성권,이화은,서찬종 대한내분비학회 2000 Endocrinology and metabolism Vol.15 No.4

Background: Propylthiouracil (PIV) and methimazole (MMI) were widely used for the treatment of hyperthyroidism. Hepatic injury caused by these agents is a rare but serious complication. This study is to investigate the clinical features of hepatotoxicity from antithyroid drugs. Methods: We reviewed 17 cases of hepatic injury during treatment with antithyroid drugs in patients with hyperthyroidism. Included were 6 cases we experienced and 11 cases reported in Korean literature from 1986 to 1999. We analyzed the clinical features of hepatic injury. Results: Of 17 cases of hepatic injury, 12 were PTU cases and 5 MMI cases. The mean age of PTU cases was 40 years with 6/12 patients over 40 years old and 2/5 MMI cases were over 40 years old. The dose of PTU was 300 mg/d or more in 10/12 cases (83%) and the dose of MMI was 30 mg/d in 3/5 cases (60%). The hepatic injury occurred within 3 months in 8/12 PTU cases (67%) and within 2 months in 4/5 MMI cases (80%). The duration of hepatic injury tended to be longer in MMI cases than in PTV cases (median; 80 vs 41 days, p=0.102). In PTU cases, the duration of hepatic injury was correlated with the duration of drug use before hepatic injury (p$lt;0.05). All of 8 biopsied cases who took PTU had predominantly hepatocellular necrosis. Two biopsied cases who took MMI had cholestatic jaundice and nonspecific abnormality, respectively. Biochemical findings of all MMI cases were compatible with cholestatic jaundice. As to the treatment of hyperthyroidism after hepatic injury, 4/12 PTU cases were treated with RAI therapy, 5 with MMI and one with surgery, and treatment was unknown in two. On the other hand 3/5 MMI cases interestingly entered into spontaneous remission after hepatic injury and 2/5 had RAI therapy. Hepatic dysfunction recurred in each one whom treatment by changing to MMI or PTU was tried on. Conclusion: Most of hepatic injury during treatment with antithyroid drugs developed within two to three months of drug use. The hepatic injury related to PTU was mainly cytotoxic whereas that related to MMI was cholestatic. Since there is a cross-reaction between PTU and MMI in hepatotoxicity, RAI therapy or operation shoud be considered as an alternative treatment of hyperthyroidism after hepatic injury (J Kor Soc Endocrinol 15:554-560, 2000).

성인에서 비만에 대한 자가 평가

황재경,김홍규,공희상,윤효중,황용하,이기영,정연실,이성광,박혜영,김갑환,최원철,강문호 대한비만학회 2002 The Korean journal of obesity Vol.11 No.4

연구배경 : 일반인들의 비만에 대한 자가평가는 객관적인 기준에 의하기보다는 주관적인 것으로, 이는 체중조절에 대한 부적절한 노력을 이끌 가능성이 있다. 본 연구는 우리나라 성인을 대항으로 비만에 대한 자가평가와 체질량지수를 기준으로 정의한 객관적인 비만도 사이의 차이를 알아보고, 비만에 대한 인식에 영향을 주는 사회환경적 요인을 규명해 보고자 하였다. 방법 : 가천의대 길병원의 건강증진 센터에 내원하여, 건강검진을 받은 561명 (남 341 : 여 220) 의 성인을 대상으로 하였다. 체질량지수 20미만, 20 ~ 24.9, 25 ~ 29.9, 30이상 (kg/㎡)에 따라 네 군으로 분류하였고, 설문조사 상 자신의 체형에 대한 인식 (마른 편, 적당, 비만, 매우비만)과의 일치도를 살펴보았다. 결과 : 대상자의 연령은 37±13세, 남녀 비는 1.5:1, 체질량지수는 22.7±3.2 kg/㎡, 복부-둔부 둘레비는 0.85±0.07이었다. 체질량지수 (20미만, 20 ~ 24.9, 25 ~29.9. 30이상 (kg/㎡))를 기준으로 한 경우와 자가평가 (마른편, 적당, 비만, 매우 비만)에 대한 일치도는 각각 56%, 52%, 49% 그리고 89% (kappa=0.26)이었다. 그리고 , 체질량수 25 kg/㎡ 이상인 비만인 남성의 44%가 자신을 비만하지 않다고 평가하고 있었으며, 체질량지수 25 kg/㎡ 미만인 여성의 43%가 자신을 비만하다고 인식하였다. 비만에 대한 자가 평가가 적절한 군과 그렇지 않은 군 사이에 연령, 교육 수준, 거주지역 등에 의미 있는 차이는 관찰되지 않았다. 결론 : 우리 나라 성인에서 객관적인 비만도와 일반인의 자가 평가 사이에는 상당한 차이가 있다는 것을 알 수 있었다. 남성의 경우에는 자신의 비만에 대한 인식이 부족하였고, 여성의 경우에는 비만하지 않은 경우에도 자신을 비만하다고 과평가하는 비율이 높았다. 따라서, 일반인들을 객관적으로 비만 기준으로 정확히 평가하고, 올바른 신체이미지를 가질 수 있도록 교육하는 것이 필요함을 알 수 있었다. Background : Obesity has become a matter of great public concern in Korea with its increasing prevalence in recent years. People should properly recognize themselves whether to be obese or not before seeking medical attention. However self assessment of obesity may be erroneously subjective and misleading. This study is to investigate the possible discrepancy between self-assessment of obesity and obesity defined by BMI in Korean adults. Materials And Methods : Five hundred sixty one adult subjects (341 men and 220 women) who took a routine health examination in Gachon Health Center were included in this study. We analyzed the data obtained from health examination and a questionnaire including self-assessment of obesity categorized as underweight, normal, obese and severely obese. Body mass index (BMI) ≥ 25 kg/㎡ is defined as obese, BMI ≥ 30 kg/㎡ as very obese and BMI <20 kg/㎡ as underweight. Results : The age of the subjects was 37±13 years, male to female ratio 1.5:1, the BMI 22.7±3.2 kg/㎡, and the WHR 0.85±0.07. The concordance rates between self-assessment of obesity and obesity defined by BMI were 56%, 52%, 49% and 89% (kappa=0.26) respectively in underweight, normal, obese and very obese. 44% of men with obesity (BMI ≥25 kg/㎡) assessed themselves to be non-obese, whereas 43% of non-obese women (BMI ≥25 kg/㎡) assessed themselves to be obese. There were no differences in age, education level, and residential area between the groups who correctly assessed their obesity and did not. Conclusions : There were significant discrepancies between self-assessment of obesity and obesity defined by BMI in Korean adults. Significant proportion of men with obesity underestimated their obesity, while significant proportion of non-obese women overestimated their fatness. These results suggest that public education be required to provide the proper definition of obesity and avoid the misleading in its management.