경남 함안 지역 두 비닐하우스에서 재배된 수박에 발생한 잎점무늬병의 원인 병원균 동정

이성광,안선민,김경희,박숙영 한국식물병리학회 2025 식물병연구 Vol.31 No.2

우리나라 수박(Citrullus lanatus) 재배면적은 약14,000 ha로, 이 중 비닐하우스를 활용한 온실 재배가 약 25-30%를 차지한다. 특히 겨울 수박 재배는 고소득 작물로, 특히 경남 함안군은전체 생산량의 70% 정도를 차지하고 있다. 2024년과 2025년 사이에 함안의 37개 온실 중 동쪽에 위치한 두 개의 온실에서 어린 잎에 반점이 나타나기 시작하였다. 검은 반점이 점차 동심원으로 확대되어 결국 마르거나 조기 낙엽으로 이 두 온실의 수박의 70% 이상에 영향을 미쳤다. 원인 병원균은 형태학적 및분자학적 분석을 통해 Cercospora cf. citrullina로 동정되었다. 병원균은 감자 한천 배지와 옥수수가루 한천 배지에서 균사 생장 및 포자 형성이 매우 느렸다. 병원성 분석 결과, 분리된 균주가 잎점무늬병의 원인 병원균임이 확인되었으며, 감염된 잎에서 병원균이 재분리되어 코흐의 가설을 충족하였다. 본 연구 결과는 향후 이 병에 대한 경종적 및 화학적 방제를 포함한 효율적인 방제 전략 개발에 기여할 것이다. The area dedicated to watermelon (Citrullus lanatus) cultivation in Korea spans approximately 14,000 hectares, with greenhouse cultivation accounting for about 25-30% of this total. Notably, winter watermelon cultivation is considered a high-income crop, and Haman-gun in Gyeongsangnam-do is a prominent production area, contributing approximately 70% of the total output. Between 2024 and 2025, leaf spots began to appear on young leaves in two greenhouses located on the eastern side of 37 greenhouses in Haman. The symptoms gradually progressed from spots to concentric circles, resulting in a disease that affected more than 70% of the watermelons in these two greenhouses. The causal pathogen was identified both morphologically and molecularly as Cercospora cf. citrullina. The pathogen exhibited very slow growth, and spore development was also slow under potato dextrose agar and cornmeal agar media. Pathogenicity assays confirmed that the isolates were the causal agents of leaf spot disease, and the fungus was reisolated from the infected leaves, thus fulfilling Koch’s postulates. Our findings will contribute to the development of effective control strategies for this disease, including methods for cultural and chemical controls in the future.

MS-HEMs: An On-line Management System for High-Energy Molecules at ADD and BMDRC in Korea

이성광,조수경,박재성,김광연,노경태 대한화학회 2012 Bulletin of the Korean Chemical Society Vol.33 No.3

A pioneering version of an on-line management system for high-energy molecules (MS-HEMs) was developed by the ADD and BMDRC in Korea. The current system can manage the physicochemical and explosive properties of virtual and existing HEMs. The on-line MS-HEMs consist of three main routines: management, calculation, and search. The management routine contains a user-friendly interface to store and manage molecular structures and other properties of the new HEMs. The calculation routine automatically calculates a number of compositional and topological molecular descriptors when a new HEM is stored in the MS-HEMs. Physical properties, such as the heat of formation and density, can also be calculated using group additivity methods. In addition, the calculation routine for the impact sensitivity can be used to obtain the safety nature of new HEMs. The impact sensitivity was estimated in a knowledge-based manner using in-house neural network code. The search routine enables general users to find an exact HEM and its properties by sketching a 2D chemical structure, or to retrieve HEMs and their properties by giving a range of properties. These on-line MS-HEMs are expected be powerful tool for deriving novel promising HEMs.

악성 흉선종 절제술 중의 성공적인 횡격막 신경 직접 재건술

이성광,김연수,박경택,장우익,류지윤,김창영,조성준,최현민 대한흉부외과학회 2009 Journal of Chest Surgery Vol.42 No.3

We performed nerve resection and reconstruction of the phrenic nerve in a 63-year-old female patient who underwent complete resection of a malignant thymoma. The left phrenic nerve was completely encased by the tumor for 2 cm. Thus, a 3 cm long piece of phrenic nerve with 5 mm margins of safety on each end was resected and it was directly anastomosed in an end-to-end fashion. At 11 months after reconstruction, fluoroscopy demonstrated adequate and symmetric motion of both hemidiaphragms, which indicated the restoration of phrenic nerve function. The pulmonary function test results were comparable to those obtained preoperatively at 30 months. There has been no evidence of recurrence at the recent follow up visits. 63세 여자 환자의 악성 흉선종 절제수술 시에 횡격막 신경의 절제 및 복원술이 시행되었다. 수술 소견상 좌측 횡격막 신경이 2 cm 정도의 길이로 종양에 완전히 둘러싸여 있어서 위아래로 5 mm 길이의 여유를 두고 3 cm 정도의 횡격막 신경을 절제하였으며 직접 단단 문합 하였다. 수술 후 11개월에 시행한 투시진단에서 양측 횡격막은 적절하고 대칭적인 움직임을 보임으로서 신경기능의 회복을 시사했다. 수술 후 30개월에 시행한 폐 기능 검사 결과는 수술 전의 소견과 유사하였다. 환자는 재발 없이 현재 외래 추적 관찰 중이다.

CO₂ 냉동시스템용 액상배관에서 PAG 및 POE 오일회수 특성에 관한 실험적 연구

이성광 대한설비공학회 2009 설비저널 Vol.38 No.12

신약설계를 위한 화합물 DB-chemical Database for Drug Design-

이성광,노경태,Lee, Seong-Gwang,No, Gyeong-Tae 한국과학기술정보연구원 2001 지식정보인프라 Vol.5 No.-

화학구조 D B는 그 목적에 다양하게 분류될 수 있는데, 유사한 약효를 검색하기 위한 유사도 검색(similarity search) DB와 유기합성을 위한 reaction DB, 실험이나 계산으로 얻은 물성을 모은 property DB, 생물학적 검증 데이터를 모은 activity DB등이 있다. 이러한 화학 D B는 신약을 설계하는 입장에서 볼 때, 앞에서 말한 다양한 D B로서의 목적을 모두 충족시킬 수 있는 유기적인 설계가 바람직하다.

On-line SPE-HPLC Method using Alumina Filtering to Selectively Extract Phenolic Compounds from Environmental Water

이성광 대한화학회 2010 Bulletin of the Korean Chemical Society Vol.31 No.12

A on-line SPE (solid phase extraction)-HPLC preconcentration method was developed for the determination of phenolic compounds at trace levels in environmental water sample. XAD-4 and Dowex 1-X8 were used as sorbent in the on-line SPE-HPLC method for the selective enrichment of nine phenolic compounds, which are included in the priority pollutants list of the US EPA. Also alumina prefiltering considerably reduced the amount of interfering peaks due to humic substances that could accumulated due to the preconcentration step and prevent quantification of polar phenolic compounds in environmental water samples. This method was used to determine the phenolic compounds in tap and river water and superiority to the US EPA 625 method in its enrichment factor, pretreatment time, recoveries,and detection limit. The limits of detection were in the range of 0.3 - 0.9 μg/L in tap water sample.

복부대동맥류 환자에서의 수술 후 사망의 위험인자 분석

이성광,전희재,박경택,윤영철,한일용,이양행,조광현 대한흉부외과학회 2010 Journal of Chest Surgery Vol.43 No.6

배경: 최근에 경피적 대동맥 스텐트 삽입술의 비약적인 발전으로 외과적 수술이 감소하고는 있으나,여전히 근치를 위한 치료로 인정되고 있다. 저자들은 지난 6년 8개월간 시행한 복부 대동맥류의 수술성적 및 그 예후에 미치는 영향인자에 대해 분석하여 보았다. 대상 및 방법: 2001년 5월부터 2005년6월까지, 2007년 4월부터 2009년 11월까지 복부 대동맥류로 수술 받은 환자 36명을 대상으로 하였다. 수술의 적응은 파열, 60 mm 이상의 최대직경, 내과적으로 조절 안되는 고혈압이나 통증이 있는경우 등이었다. 결과: 환자들의 평균 나이는 69.67±6.97세(57∼84세)였고, 남자가 32명(89.2%), 여자가 4명(10.8%)이었다. 신동맥 하부부터 장골동맥 위까지 진행된 경우는 8명(22.2%), 장골동맥까지 진행된 경우는 28명(77.8%)이었다. 진단 당시 대동맥이 파열되어 있었던 환자들은 13명(36.1%)이었다. 대동맥의 평균 최대직경은 73.7±13.3 mm (60∼100 mm)였다. 수술은 대부분 정중 복부절개를 통한복강 내 접근으로 시행하였고, 응급수술은 10명의 환자(27.8%)에서 시행하였다. 전체 환자 중 3명이사망하여 전체 사망률은 8.3%였고, 파열된 환자의 사망률은 23.1%, 파열되지 않은 환자의 사망률은0%였다. 수술 후 합병증으로는 창상감염 3예, 패혈증 2예, 신부전 2예, 폐렴 1예씩 있었다. 사망에 영향을 주는 인자로는 수술 전 불안정한 활력징후 수혈, 또는 실신이 있었던 경우, 과거력 상 당뇨병이있는 경우, 동맥류가 파열된 경우와 응급수술 등이 있으며, 합병증 중 패혈증, 신부전이 발생한 경우와 술중 심폐소생술을 시행한 경우가 통계적으로 의미 있었다(p<0.05). 결론: 파열된 복부대동맥류에 대한 응급수술은 여전히 높은 사망률을 보이나, 파열되지 않은 복부대동맥류의 수술은 비교적 안전하게 진행할 수 있다. 비록 경피적 대동맥 스탠트 삽입술이 최근의 치료 경향이나 파열되지 않은동맥류의 계획된 수술은 시술과 관련된 부작용이나 반복된 검사의 불편함을 줄이고 좋은 결과를 얻을 수 있을 것으로 생각한다. Background: Despite the rapid expansion of percutaneous endovascular repair, open surgical repair is still recognized as an option to achieve a cure. We retrospectively analyzed over a 6 year period the surgical outcomes,the complications and the mortality-related factors for patients with abdominal aortic aneurysms. Material and Method: We analyzed 36 patients who underwent surgery for abdominal aortic aneurysms between May 2001 and June 2005, and between April 2007 and November 2009. The indications for surgery were rupture, a maximal aortic diameter >50 mm, and medically intractable hypertension or pain. Result: The mean patient age was 69.67±6.97 years (range: 57 to 84 years). Thirty two patients (88.9%) were males and 4 patients (11.1%) were females. Extension to the iliac artery existed in 28 patients (77.8%). Thirteen patients (36.1%) had ruptured aortic aneurysms. The mean maximal diameter of the aorta was 73.7±13.3 mm (60 to 100 mm). Surgery was performed by a midline laparotomy and 10 patients (27.8%) underwent emergency surgery. The mortality rate was 8.3%; the mortality rate for the patients with ruptured aneurysms was 23.1% and the mortality rate for patients with unruptured aneurysms was 0%. The postoperative complications included wound infection (3 cases), sepsis (2 cases),renal failure (2 cases) and pneumonia (1 case). Unstable vital signs, pre-operative transfusion, ruptured aneurysm,emergency surgery, comorbidity (DM and syncope) and complications (sepsis and renal failure) were the statistically significant mortality-related factors (p<0.05). Conclusion: Emergency surgery for ruptured aortic aneurysms continues to have high mortality, but the unruptured cases are repaired with relative safety. Even though endovascular aortic repair is the trend for abdominal aortic aneurysms, an elective operation of the unruptured aneurysms could decrease the procedure’s morbidity and the inconvenient for repeat evaluation with good surgical results.

위늑막루에 의한 농흉의 치험 −1예 보고−

이성광,이양행,전희재,윤영철,황윤호,박경택,최창수 대한흉부외과학회 2010 Journal of Chest Surgery Vol.43 No.3

Gastropleural fistula is a rare complication of prior lung surgery, gastric ulcer, trauma and malignancy. A 62 year old female patient who had received surgical repair of a perforated gastric wall 10 years prior, underwent open pleural decortication. At 4 days after surgery, food residuums were noticed at the chest bottles. Hence, an emergency esophagogram was done. The esophagogram revealed a gastropleural fistula. The patient received a total gastrectomy, intra-abdominal diaphragmatic repair and massive thoracic saline irrigation through a previous thoracic wound. The patient was discharged 11 days after surgery without other morbidity. 위늑막루는 이전의 폐수술 병력, 위궤양의 합병증, 외상, 악성종양 등에 의해 일어날 수 있는 흔하지 않은 합병증이다. 10년전에 위장천공의 외과적 봉합술을 받았던 62세 여자 환자로 좌측 농흉이 발생하여 개흉하에 흉막 박피술을 시행하였다. 수술 후 4일째, 음식물이 흉관을 통해서 배액 되어서 응급 위식도 조영술을 시행하였다. 위식도 조영술상 위늑막루를 발견하였다. 환자는 위전절제술 및 횡경막 봉합을 시행하고, 이전의 흉부창상을 통해 흉강을 세척하였다. 특별한 문제 없이 수술 후 11일째 퇴원하였다.

개흉술이 필요했던 다발성 외상환자에 대한 임상적 고찰

이성광,정성운,김병준 대한흉부심장혈관외과학회 1998 Journal of Chest Surgery Vol.31 No.8

Background: Multiple trauma patients have rapidly increased due to traffic accidents, industrial disasters, incidental accidents, and violence. Multiple trauma can involve injuries to the heart, lung, and great vessels and influence the lives, necessitate prompt diagnosis and treatment. Most of the thoracic injuries can be managed with conservative method and simple surgical procedures, such as closed thoracostomy, but in certain cases open thoracotomy is necessary. Materials and methods: The author analyzed the surgical result of 70 cases of open thoracotomy after multiple organ injury including thoracic organ. Results: The most common type of thoracic lesion was hemothorax with or without pneumothorax and diaphragmatic rupture was the second. Sixty percent of the patients were associated with bone fractures, 42.9% with abdominal injuries, and 37.1% with head injuries. The modes of operation were ligations of torn vessels for bleeding control(48.6%), repair of diaphragm(35.7%), and repair of lung laceration(25.7%) in this order of frequency and additional procedures were splenectomy(14.3%), hepatic lobectomy (8.6%) and repair of liver lacerations(5.7%). Postoperative complications were atelectasis (8.6%), wound infection (8.6%), and pneumonia(4.3%). Postoperatively six patients died(The mortality rate was 8.6%) and the causes of death were respiratory failure(2), acute renal failure(2), sepsis(1), and hypovolemic shock(1).

심장자창의 수술치험례: 8례 보고

이성광,박동식,김종원 대한흉부심장혈관외과학회 1973 Journal of Chest Surgery (J Chest Surg) Vol.6 No.2

8 cases of the heart wound which had been successfully operated on were reported. These wounds were caused by knife in 6 cases, by traffic accident in one case and by explosion in one case, and clinically classified as Hemothorax type in 4 cases, acute Tamponade type in 3 cases and combined type in one case. Some important problems for the diagnosis and treatment of stab wound of the heart were also discussed.