인위적 진화의 세계

이재원(Lee, Jae-Won) 동남어문학회 2012 동남어문논집 Vol.1 No.33

This writing is an attempt to examine the logic behind artificial evolution in the early writing of Lee Kwang-su. According to his account, human civilization is the result of artificial evolution. By defining human personality as abilities of artificial evolution, he tried to change the way of basic understanding human being. He presented in the existence which comes true the essence of the human being which is such the civilized person. At logic of his artificial evolution, the problem of civilization was converted with creation of individual all who have the desire toward civilization. He looked at the situation and position of korean society from the viewpoint of world history and admitted the differential temporality which is dividing between korean society and western civilization. The Lee’s ideas of artificial evolution serves as alternative way to jump over the differential temporality. In the early writing, the methods of the artificial evolution are reform of education system, reading literature and revolution. Through this method, Lee tried to prepare ‘Civilized people’ and ‘shared commitment to social values’ that are practical foundation of artificial evolution.

Lovastatin을 생산하는 식용버섯 선발과 HMG-CoA reductase 저해 효과

이재원,이수민,곽기섭,이지윤,최인규,Lee Jae-Won,Lee Soo-Min,Gwak Ki-Seob,Lee Ji-Yoon,Choi In-Gyu 한국미생물학회 2006 미생물학회지 Vol.42 No.2

국내에서 식용버섯으로 이용되고 있는 8종 균주의 자실체와 균사체로부터 콜레스테롤 합성을 저해하는 lovastatin 생산과 고지혈증 억제활성을 탐색하였다. TLC 분석으로 lovastatin생산 유무를 검색한 결과 자실체와 균사체의 추출물에 대해 Rf값이 표준물질콰 같은 약 0.46에서 뚜렷한 밴드가 형성됨을 확인하였다. 자실체로부터 lovastatin 추출을 위한 용매로는 water/acetonitrile/methanol (5:2.5:2.5)을 사용하였을 매 가장 효과적인 lovastatin 생산량을 보였다. Lovastatin 생산량은 자실체 중에서는 Pleurotus ostreatus가 0.98 mg/g (dry biomass)으로 가장 높은 생산량을 나타냈고 균사체 배양액 추출물에 대해서도 P. ostreatus가 21.90 mg/L로 높은 생산량을 나타냈다. 3-Hydroxy-3-methylglutaryl-CoA (HMG-CoA) reductase 저해활성에서는 자실체에서 P ostreatus가 67.8%, 균사체에서 P. ostreatus와Laetiporus sulphureus가 각각 37.2%, 29.1%의 저해활성을 보였다. L. sulphureus는 lovastatin 생산량에 비해 높은 저해활성을 나타내서 lovastatin 이외의 다른 고지혈증 억제물질을 GC/MS로 분석한 결과 대사산물로 분비되는 식물성 sterol 물질인 campesterol과 gamma-sitosterol이 검출되었다. This research was performed to determine the production of lovastatin and its HMG-CoA reductase activity produced by fruit bodies and mycelial liquid cultures of domestic edible mushrooms (8 fungal strains). By deter-mining TLC analysis for the confirmation of the presence of lovastatin, all the extracts from fruit bodies and mycelial liquid culture showed same Rf value (0.46), whick was identical to that of the standard lovastatin. In order to extract lovastatin from fruit body, the mixture of water/acetonitrile/methanol was chosen as the most effective solvent. Extracts from fruit body and mycelial liquid culture of pleurotus ostreatus produced the high-est lovastatin 0.98 mg/g based on dry biomass, and 21.90 mg/L, respectively. In the inhibition rate of 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) reductase, the highest was obtained in P. ostreatus as 67.8% among fruit bodies, and the rates of mycelial liquid culture extracts from P. ostreatus and Laetiporus sulphureus were 37.2% and 29.1%, respectively. Unusually L. sulphureus showed high inhibition rate with low content of lovastatin due to the contribution of campesterol and gamma-sitosterol with hypocholesterolemic activity as metabolites.

Ti-15V-3Al합금의 시효거동과 열처리에 따른 고온 기계적 특성

이재원,이백희,이규환,김영도,Lee Jae Won,Lee Back-Hee,Lee Kyu Hwan,Kim Young Do 한국재료학회 2004 한국재료학회지 Vol.14 No.1

Titanium alloys are the one of promising candidate materials for medium high temperature parts in the aircraft, automobile, petrochemistry and electrochemistry because of their high strength with low density in medium high temperature. In this study, the effects of aging and heat treatments on the mechanical properties of Ti-15-3 alloy in medium high temperature, which was $400^{\circ}C$, were studied. Solid solution treatment was performed at $8000^{\circ}C$ of $\beta$ phase region for 1 h and the alloy was quenched in water. The alloy was aged at $5000^{\circ}C$ of $\alpha$ and $\beta$ two-phase region for 1, 2, 4, 8, ... and 100 h to increase the mechanical property. The $\beta$ single phase was observed at all parts of specimens in Ti-15-3 alloy after ST. As the aging at $500^{\circ}C$, fine precipitates of a phase was generated from matrix of $\beta$ phase and the microstructure was consisted of weaving structure such as Widmanstiitten a phase. The most suitable aging time is 24h in$ 400^{\circ}C$. At this time, strength is 1164 MPa and elongation is about 12%. In room temperature, elongation of Ti-15-3 alloy aged at $500^{\circ}C$ for 16 h is poor (=3%) in spite of high tensile strength (1458 MPa).

사상의학초본권(四象醫學草本卷)과 동의수세보원(東醫壽世保元)에 나타난 이제마(李濟馬)의 사상의학관(四象醫學觀)에 관한 비교고찰(比較考察)

이재원,송일병,Lee, Jae-won,Song, Il-byung 사상체질의학회 1999 사상체질의학회지 Vol.11 No.2

Purpose: This studied by the comparative method the view of Lee Je-ma's Constitutional Medicine expressed Sasang ChobonGuen and Dongyi Suse Bowon. 2. Method: I studied the view of Lee Je-ma's Constitutional Medicine classified broadly 'General view of life' and 'Constitutional view of life expressed SangChonbonGuen and Dongyi Suse Bowon. 3. Results & Conclusion: Sasang ChobonGuen gathered 'Seongmoung-Ron', 'Sadan-Ron', 'Hwakchoong-Ron', 'Byeonjeong-Ron' and a part of 'Jangbu-Ron' of Dongyi Suse Bowon. It is insufficient the explanation of 'CheonGi', but the fundamental spirit is same. The study of Soyangin is done earlier, the studies of Soeumin, Taeumin, Taeyangin is done later.

Safety Guide_기고문 - 조명의 역사 및 향후 발전방향

이재원,Lee, Jae-Won 한국제품안전협회 2010 제품안전 Vol.195 No.-

산화ㆍ환원처리된 $UO_2$ 분말의 분쇄특성 연구

이재원,이정원,Lee Jae-Won,Lee Jung-Won 한국자원리싸이클링학회 2002 資源 리싸이클링 Vol.11 No.4

핵연료 원료인 $UO_2$ 분말을 사용해 원자로에서 연소된 사용후 핵연료 소결체를 모의 제조하여 1회 산화ㆍ환원처리하여 분말로 만든 후, 건ㆍ습식 attrition 분쇄에 따른 분말의 특성 및 소결성을 조사하였다. 분쇄에 의한 분말의 평균입자크기는 건식분쇄의 경우에는 1 $mu extrm{m}$ 이하인 미분말이 쉽게 생성되었으나, 습식분쇄에서는 그 이상의 분말만이 생성되었다. 그리고 분쇄분말의 비표면적은 건식분쇄한 경우가 습식분쇄한 경우 보다 높았다. 분말의 미세구조는 건식분쇄에 의해서는 느슨한 응집체가 형성되었으며, 습식분쇄 분말은 압분성이 낮은 불규칙적이고 각진 입자형태를 나타내었다. 건식분쇄에 의해서 압분체 밀도는 크게 증가하며 소결체 요구 조건을 만족하는 이론밀도의 95%이상이 되고 평균 결정립 크기가 8 $\mu\textrm{m}$이상인 소결체를 얻을 수 있었다. The characteristics of dry and wet milled powder prepared by 1 cycle OREOX (oxidation and reduction of oxide fuels) treatment were investigated using the simulated spent fuel pellet. Sintered pellets simulating spent nuclear fuel burned in reactor were fabricated from $UO_2$ powder using as a starting material in fabrication of nuclear fuel. The 1 cycle OREOX-treated powder was prepared by only one path of oxidation md reduction of the simulated pellet. Powder having average particle size of less than 1 $\mu\textrm{m}$ could be easily obtained by dry milling, but not be achieved by wet milling. And, specific surface area of dry milled pow-der was higher than that of wet milled powder. Dry milled powder formed loose agglomerate, while wet milled powder showed the shape of irregular and angular particles. Dry milled powder provided higher green density, resulting in higher sintered density of higher than 95% TD and average grain size of larger than 8 $\mu\textrm{m}$ satisfying the standard specification of sintered pellets.

자연기흉의 개흉술 적응과 수술성적에 관한 연구

이재원,김근호,Lee, Jae-Won,Kim, Geun-Ho 대한흉부심장혈관외과학회 1987 Journal of Chest Surgery (J Chest Surg) Vol.20 No.1

The records of 268 patients, who were diagnosed as spontaneous pneumothorax during the period 1975 to 1984, treated at the department of thoracic and cardiovascular surgery, Hanyang University Hospital, were reviewed retrospectively to evaluate the effect of surgical intervention on each indications. Of these,.61 patients [22.8%] were taken operation to treat the pneumothorax after closed thoracostomy. We have classified the 61 patients to evaluate the therapeutic effect on each indications. And the therapeutic effect is based on the chest tube indwelling days. The results were as follows: 1. The chest tube indwelling days of the group who were taken closed thoracostomy only was average 14.13*9.17 days [range 5-66 days], and that of the group who were finally taken the thoracotomy after closed thoracostomy was 21.85*12.30 days [range 5-55 days]. 2. The indications of thoractomy were thoracoscopic findings, recurrence and continuous air leakage. 3. The chest tube indwelling day of the group who was taken thoracotomy by thoracoscopic findings was average 11.67*6.51 day, that was relatively short compared to those of the other groups. 4. The continuous air leakage group after closed thoracostomy was subdivided into three subgroups, continuous air leakage in 1st attack, thoracoscopic findings in 1st attack, and recurrence. 5. Of these, the chest tube indwelling day of the subgroup, who was taken operation by thoracoscopic findings, was 21.33e8.26, that was relatively short compared with those of the other subgroups. We use the thoracoscope as excellent diagnostic tool to detect the operation indication in the spontaneous pneumothorax patients. And we gain the benefits to shorten the chest tube indwelling days and admission days, and also to protect the recurrence.

심실중격결손증을 동반한 관상동정맥루 -치험 1예-

이재원,이홍섭,김창호,Lee, Jae-Won,Lee, Hong-Seop,Kim, Chang-Ho 대한흉부심장혈관외과학회 1986 Journal of Chest Surgery (J Chest Surg) Vol.19 No.2

Congenital coronary arteriovenous fistula is uncommon disease, and was first described by Krause in 1865. About 20% of the cases, it associates additional congenital heart diseases. A 5-year-old female patient was diagnosed as coronary AV fistula with VSD, and was taken surgical correction under cardiopulmonary bypass. VSD was small and subarterial in type, and the fistula was dilated as adult thumb tip size at its distal portion. VSD was closed directly through the pulmonary arteriotomy and the aneurysmal dilation was opened vertically, then it was obliterated using 5-0, 6-0 prolene continuous suture fashioning into a long slender tube. Postoperative course was uneventful.

다발성 원발성 식도종양 1례 보

이재원,강정호,지행옥,Lee, Jae-Won,Gang, Jeong-Ho,Ji, Haeng-Ok 대한흉부심장혈관외과학회 1987 Journal of Chest Surgery (J Chest Surg) Vol.20 No.2

A 51 year-old male was admitted with the chief complaints of swallowing difficulty and pain on neck and upper chest for 2 months prior to admission: He was taken biopsy under esophagoscopy, and the result was squamous cell carcinoma. Preoperatively we studied the esophagogram and chest CT. On these, we found the main appreciable mass at midesophagus easily. But, we missed the upper cervical unexpected mass. So we performed the esophagectomy and lymph node dissection from upper clavicle level to the esophagogastric junction by thoracic approach as wide as possible, and cervical esophagostomy and feeding gastrostomy also. At that evening we reviewed the studied films in detail, and we found another mass lesion at C4-C6 level of cervical esophagus. We performed the 2nd operation e.g. cervical esophagectomy on next morning without hesitation. Between these two masses, there was almostly normally looking skip area grossly. The squamous cell carcinoma of the esophagus could be multicentric in character and may have skip area. But, we heard little reports until now. The two masses could be different in origin or be same probably by submucosal spreading. Anyway, it was an alarming case to the surgeon not to neglect the another possible lesions in squamous cell type. Postoperative course was uneventful, he took G-tube feeding with no problems on 7th postoperative day. Now he took the postoperative irradiation at out patient department.

국제학술회의 참관기-제6차아시아 심혈관외과학회

이재원,Lee, Jae-Won 한국과학기술단체총연합회 1998 과학과 기술 Vol.31 No.5

지난2월18일부터 3일간 일본 동경 게이오플라자 호텔에서 아시아의 심혈관 학자들이 참석한 가운데 제6차 아시아 심혈관학회의 학술발표가 열렸다. 대회 첫날엔 서울대 서경필교수가 한국의 심혈관외과 현황에 대한 브리핑을 했고 한국측에서 11개의 논문이 발표되었다. 필자인 울산의대 서울 중앙병원 이재원 교수는 「대동맥 판막 치환후 좌심실근 비후의 변화」라는 논문을 발표해 큰 관심을 모았다.