상한론의 '기기상충(其氣上衝)'과 '계지탕(桂枝湯)'에 대한 연구

이승준,김영목,Lee, Seung-Jun,Kim, Yeong-Mok 대한한의학방제학회 2012 大韓韓醫學方劑學會誌 Vol.20 No.2

In pathologically analyzing, 'Qi(氣)' is fall downed 'Zheng-Qi(正氣; Base energy of human body)' or 'Wai-Gan-Xie-Qi(外感邪氣; poisoned energy from outside of human body)'. And all extroverted symptoms from this 'Qi(氣)' is 'Shang-Chong(上衝)'. Also this symptom's basic mechanism is deficiency of 'Zhong-yang(中陽; basic active energy acting pivot)' by non-proper 'Xia-fa(下法; treatment way getting out focus to down side)' at early days of 'Tai-Yang-bing (太陽病; Primary stage symptoms when the cold energy of the outside tresspasses the external layer of body)'. And comparing herbs in medicines for treating 'Shang-Chong(上衝)' in Shang han lun with Japanese in Shang-han medical practitioner's view, there is 'Ping-Chong(平衝; Supress out bursting energy)''s effect when use 'Gui-zhi(桂枝; Cinnamomum cassia loureirii zeylanuicum)' for mass dosage. Based on these, 'Qi-Shang-Chong(氣上衝)' means all of the symptom's aspects which called 'Yang(陽)''s aspect that is extrovesity, dynamic and imminent by results of the experiment about Cinnamaldehyde which are the main ingredients of 'Gui-zhi(桂枝; Cinnamomum cassia loureirii zeylanuicum)' and clinical data of 'Gui-zhi-tang(桂枝湯)'.

국내 최초 도로터널 진출입로를 고려한 적정 다분할 굴착단면설계 사례연구

이승준,신현강,이현섭,김우선,정동호,Lee, Seung-Jun,Sin, Hyeon-Gang,Lee, Hyeon-Seop,Kim, U-Seon,Jeong, Dong-Ho 한국지반공학회 2011 지반 : 한국지반공학회지 Vol.27 No.5

중심과 편심축력을 받는 중공 프리캐스트 콘크리트 합성기둥의 압축강도

이승준,서수연,김강수,Lee, Seung-Jun,Seo, Soo-Yeon,Kim, Kang-Su 大韓建築學會 2015 大韓建築學會論文集 : 構造系 Vol.31 No.2

In this paper, in order to evaluate the applicability of KBC formula in calculating the strength of hollow-precast concrete (HPC) column for design purpose, a compressive capacity was evaluated through the concentric and eccentric test for the columns with various material strength and hollow size, respectively. Based on the test result, the suitability of code formulae was checked and the lateral confining effect of HPC composite column was also evaluated by using Mander's stress-strain relationship. Also, nonlinear sectional analysis process was performed. As a result, it was found that the strength of the HPC composite column could be suitably predicted by using KBC code formulae for design purpose. In the calculation of the compressive strength of the column by using Mander model considering the lateral confining effect of hoop, the confining effect of it in HPC was less than that in reinforced concrete column and changed corresponding to the concrete strength ratio between PC and CIP (Cast-In-Place). The effect decreases when the concrete strength of CIP is not less than that of PC. The flexural-compression capacity of HPC composite column can be suitably evaluated by using the effective strength of concrete.

미세부품가공을 위한 소형 초고속에어스펀들 개발

이승준,신인동,최수창,김용우,이종렬,이득우,Lee, Seung-Jun,Shin, In-Dong,Cha, Sao-Chang,Kim, Yong-Woo,Lee, Jong-Ryul,Lee, Deug-Woo 한국생산제조학회 2010 한국생산제조학회지 Vol.10 No.6

The development of high-speed spindle have been studied extensively for micro machining in advanced industrial countries. The research of miniaturized high-speed air spindle is important part which needs for the micro machining process of high quality. So, This study was to carry out results about design characteristics of miniaturized high-speed air spindle. We had designed 4type turbines and shaft. They were simulated in use the computer simulation programs. We made them as products. They measured RPM (revolutions per minute). As a result of experiments, there was a contrast among 4type Turbines. it reached 384,000rpm in 4.5bar of air pressure. And, We tried to compare the results of measurement whit the results of computer simulation.

MR 감쇠기가 설치된 모멘트골조의 연쇄붕괴 저항성능

이승준,김진구,민경원,Lee, Seung-Jun,Kim, Jin-Koo,Min, Kyung-Won 대한건축학회 2011 대한건축학회논문집 Vol.27 No.2

In this paper the progressive collapse resisting capacity of steel moment frames with MR dampers was evaluated. Parametric studies were carried out using a steel beam-column sub-assemblage with varying natural period and yield strength. The effect of dampers with varying damping coefficients installed in the sub-assemblage was evaluated after sudden removal of the column. Then the progressive collapse potential of a 15-story steel moment frame installed with MR dampers was evaluated by nonlinear dynamic analysis. According to the parametric study the vertical displacement generally decreased as the friction force of MR damper increased, and the dampers were effective both in elastic and elasto-plastic systems. The nonlinear dynamic analysis results of the 15-story analysis models showed that the decrease in vertical deflection of the structure with 9m span length, which showed larger deflection, was more predominant than that of the structure with 6m span length.

해양환경 하에서 Ni-Cr계 자용성 합금 코팅된 ALBC3 합금의 캐비테이션 특성 평가

이승준,김성종,Lee, Seung-Jun,Kim, Seong-Jong 해양환경안전학회 2013 海洋環境安全學會誌 Vol.19 No.5

본 연구에서는 ALBC3 합금에 Ni기 자용성 합금으로 내마모성 및 내캐비테이션 특성을 향상시키기 위하여 용사코팅 후 열처리를 실시하여 캐비테이션 특성을 평가하였다. 본 연구 결과, 자용성 합금 코팅층이 높은 경도를 나타내어 내마모성이 우수할 것으로 판단되나, 다공질의 조직으로 인해 열악한 내캐비테이션 특성을 나타냈다. 따라서 열처리 조건의 최적화가 중요하며, 본 조건에서는 열처리 온도를 높여 자용성 합금 내 B와 Si의 유동성을 증가시킴으로써 기공이나 결함을 제거하여 특성개선 효과를 기대할 수 있을 것으로 판단된다. In this study, cavitation characteristics of a thermal spray coating were evaluated in order to improve durability and cavitation resistance. For a coating material, a Ni-based self-fluxing alloy was thermal-sprayed over a ALBC3 alloy substrate and subsequently modified by heat treatment.The resulted self-fluxing coating layer had relatively high hardness compared to the base material, and thus would be expected to exhibit good durability. However, the cavitation characteristics were deteriorated due to the intrinsic porous structure of the coating. Therefore, it is essential to optimize heat treatment condition during thermal spraying coating process for self-fluxing alloy, and in this research the increase in heat treatment temperature is thought to increase the fluidity of B and Si in the self-fluxing alloy and to remove pores or defects, leading to the characteristics enhancement.

소아복통(小兒腹痛)의 병인병리(病因病理)에 관(關)한 문헌적(文獻的) 고찰(考察)

이승준,박은정,김덕곤,정규만,Lee Seung-Jun,Park Eun-Jeong,Kim Deok-Gon,Jeong Gyu-Man 대한한방소아과학회 1991 대한한방소아과학회지 Vol.5 No.1

소아안신탕(小兒安神湯)이 STRESS를 유발한 흰쥐의 적출심장(摘出心臟)에 미치는 영향

이승준,이진용,김덕곤,Lee Seung-Jun,Lee Jin-Yong,Kim Deok-Gon 대한한방소아과학회 2000 대한한방소아과학회지 Vol.14 No.2

It has long been known that SOAT is effective for sudden palpitation occurring unexpectedly in Oriental Medicine. However, effect of SOAT on the isolated heart has not been studied yet. The purpose of this study is to investigate the effect of SOAT on hemodynamics and ECG of isolated rat hearts induced by electrical stimulation using Langendorff perfusion apparatus for nonworking heart. SOAT extract was manufactured by water-alcohol precipitated method. Sprague-Dawley rats weighting $120{\sim}150g$ were used for the experiments, Subject animals were divided into four groups, which are consisted of 1) control(Group orally administered by normal saline 1ml for 14days), 2) sample A(Group orally administered by SOAT extract 1ml for 14days), 3) sample C(Group injected by SOAT extract 0.5ml after stimulation, 4) sample C(Group injected by SOAT extract 1ml after stimulation. To evluate the effects of SOAT on hemodynamics and ECG of isolated rat heart induced by stimulation, heart rate, left ventricular pressure, systolic power, diastolic power, coronary artery perfusion volume and ECG were measured using Langendorff apparatus in both stimulation mode(5 volts, 450 beats/min) and arrythmic mode(5 volts, 420 beats/min including 60 beats/min) The results obtained are as follows : 1. After receiving stressful electrical stimuli, isolated heart showed the heart rate, left ventricular pressure, systolic power, diastolic power, coronary artery perfusion volume were all decreased temporarily, but perfusion continued longer recovery to the control state appeared. However, the coronary artery perfusion volume diminished continuously. 2. The heart rates did not change significantly with both stimulation mode and arrhythmic mode, among experimental groups. 3. The left ventricular pressure showed with both stimulation mode and arrhythmic mode, the significant changes(p<0.05) especially in the injection sample group. In case of stimulation mode, low concentration injection group(0.5ml) was more significantly increased rather than high concentration group(1ml) and in case of arrhythmic mode, high density group(1ml) was so increased than the other(0.5ml). 4. For the systolic power and diastolic power, no significant changes were noticed in the stimulation mode, but in the arrhythmic mode of injection sample groups, significant change(p<0.05) was noticed in both systolic power and diastolic power. Specially the high concentration group(1ml) showed more significant increase than the low concentration group. 5. For the coronary artery perfusion volume, no significant change difference among sample groups was observed in both the stimulation mode and the arrhythmic mode. 6. For the ECG recordings, arrhythmia was induced by electrical stimulus of arrythmia mode and after the stimulus was removed, irregular wave appeared temporarily, but as perpusion continued, recovery to the control state was abtained like the stimulation mode. According to the above results, SOAT significantly changed the hemodynamic data from the electrically stressed, isolated hearts of connected Langendorff perfusion apparatus and we propose SOAT has the direct effects on the muscular function of heart.

중소규모 사업장의 남성 흡연 근로자에서 직무스트레스와 금연의지와의 관련성

이승준(Seung-Jun Lee),박신구(Shin-Goo Park),김환철(Hwan-Cheol Kim),이동훈(Dong-Hoon Lee),김기웅(Gi-Woong Kim),임종한(Jong-Han Leem),전성환(Seong-Hwan Jeon),허용석(Yong-Seok Heo) 대한직업환경의학회 2012 대한직업환경의학회지 Vol.24 No.1

일개 병원의 의료인에서 투베르쿨린 검사와 QuantiFERON-TB Gold 검사를 이용한 잠복결핵의 진단과 치료 전후의 변화

이승준 ( Seung Jun Lee ),김현식 ( Hyeon Sik Kim ),마정은 ( Jung Eun Ma ),이상민 ( Sang Min Lee ),함현석 ( Hyun Seok Ham ),조유지 ( Yu Ji Cho ),정이영 ( Yi Yeong Jeong ),김호철 ( Ho Cheol Kim ),이종덕 ( Jong Deok Lee ),김선주 ( Sun 대한결핵 및 호흡기학회 2007 Tuberculosis and Respiratory Diseases Vol.62 No.4

배경: 결핵의 완전 퇴치를 위해서는 잠복결핵의 진단 및 치료를 통해 활동성 결핵으로 진행되는 것을 예방하는 것이 중요하다. 최근 QuantiFERON-TB Gold 검사가 잠복결핵의 진단을 위한 방법으로 승인되어 사용되고 있다. 본 연구에서는 지역 3차 종합병원에 근무하는 의료인을 대상으로 투베르쿨린 검사와 QuantiFERON-TB Gold 검사를 통해 잠복결핵을 진단하고, 잠복결핵을 치료한 후 투베르쿨린 검사와 QuantiFERON-TB Gold 검사의 변화를 알아보고자 하였다. 방법: 2006년 경상대학교 병원에 근무중인 의료인 중 48명의 지원자(의사 14명, 간호사 34명, 남:여=11:37, 평균연령=29.9±5.5세, 평균근무기간=74.9±64.3개월)를 대상으로 하였다. QuantiFERON-TB Gold 검사와 투베르쿨린 검사를 시행하여 의료인에서 잠복결핵을 진단하고 두 검사의 일치율을 알아보았다. 그리고 QuantiFERON-TB Gold 검사가 양성인 지원자를 대상으로 Isoniazid(INH, 300 mg/day)와 Rifampin(RFP, 600 mg/day)을 3개월간 투약한 후 다시 투베르쿨린 검사와 QuantiFERON-TB Gold 검사를 시행하여 잠복결핵 치료 전후 두 검사의 변화를 확인하고 경결의 양성 기준에 따른 투베르쿨린 검사와 Quanti FERON-TB Gold 검사의 일치율을 알아보았다. 결과: 48명의 지원자 중 투베르쿨린 검사는 경결 양성 기준을 10 mm 이상으로 하였을 때 19명(39.6%)에서 양성, QuantiFERON-TB Gold 검사는 8명(16.7%)에서 양성이었으며 두 검사의 일치율은 77.1%, κ값은 0.468이었고, 투베르쿨린 검사의 경결 양성 기준을 15 mm로 설정하면 두 검사의 일치율은 83.3%, κ값은 0.500이었다. 1명의 활동성 결핵 환자를 제외한 QuantiFERON-TB Gold 검사가 양성인 7명의 지원자에서 잠복결핵 치료 후에도 투베르쿨린 검사와 QuantiFERON-TB Gold 검사는 계속 양성이었다. 이들에게서 시행한 투베르쿨린 검사의 평균 경결은 잠복결핵 치료 전 19.1±9.7 mm, 치료 후 43.6±25.1 mm이었다. 결론: 이번 연구의 결론으로는 투베르쿨린 검사와 QuantiFERON-TB Gold 검사로 잠복결핵의 치료반응을 평가하는 것은 부적절하다고 판단되며 향후 이에 대한 더 많은 연구가 필요할 것으로 사료된다. Background: The QuantiFERON-TB Gold assay and tuberculin skin test (TST) have been useful test for diagnosing latent tuberculosis infections (LTBI). However, there are few reports on the efficacy of the QuantiFERON-TB Gold assay and TST in evaluating the response after the treatment of LTBI. This study examined the changes in the TST and QuantiFERON-TB Gold assay before and after a treatment for latent tuberculosis in health care workers (HCWs) at a local tertiary hospital. Methods: A cohort of volunteers working as nurses and doctors who underwent a TST and QuantiFERON-TB Gold assay was established. The volunteers positive for the QuantiFERON-TB Gold assay had been treated with 3 months of isoniazid (INH) and rifampin (RFP). After completing treatment, the TST and QuantiFERON-TB Gold assay were repeated. Results: Of the 48 participants (14 doctors, 34 nurses, M: F=11:37, mean age=29.9±5.5 years, mean employment period=74.9±64.3 months), 19 (39.6%) tested positive to the TST (mean induration=19.1±9.7 mm) and 8 (16.7%) were QuantiFERON-TB Gold assay. Among them, one had active pulmonary tuberculosis. Seven volunteers were consistently positive to both the TST and QuantiFERON-TB Gold assay after being medicated with INH and RFP for 3 months. Conclusion: TST and QuantiFERON-TB Gold assay are unsuitable for evaluating the treatment response of LTBI because they were consistently positive both before and after the anti-tuberculosis medication. (Tuberc Respir Dis 2007; 62: 270-275)