유기수은의 신경독성에 대한 셀레늄의 보상작용

박정수,이효민,정용,신동천,노재훈,문영한,Park, J.S.,Lee, H.M.,Chung, Y.,Shin, D.C.,Roh, J.H.,Moon, Y.H. 대한예방의학회 1992 Journal of Preventive Medicine and Public Health Vol.25 No.1

This study was conducted to investigate the mechanism of protective effect by sodium selenite in methylmercuric chloride neurotoxicity, increasing intracellular $Ca^{2+}$concentration of the neuron. Methylmercuric chloride of 3mg/kg of body weight was administered simultaneously with sodium selenite of 5mg/kg and pretreatment of sodium selenite via intraperitoneal injection to rats. Also, effect of methylmercuric chloride($25{\mu}M,\;50{\mu}M,\;100{\mu}M$) and sodium selenite($200{\mu}M$) on free intrasynaptosomal $Ca^{2+}$ concentration were studied using the fluorescent $Ca^{2+}$ indicator fura -2 in vitro. After the treatment, at 6, 24, and 48 hours later, mercury in the cerebral cortex, liver and kidney tissues, succlnic dehydrogenase activities, adenosin-5'-triphosphate concentration, acetylcholinesterase activities, and intracellular $Ca^{2+}$ concentration in the cerebral cortex were determined in vivo. Cerebral synaptosomes of rats were incubated with methylmercuric chloride and sodium selenite in Hepes buffer for 10 minutes and free intrasynaptosomal $Ca^{2+}$ concentration were measured with fura-2 in vitro. The results were summarized as follows ; 1. The combined administration of $CH_3HgCl$ and $Na_2SeO_3$ and pretreatment of $Na_2SeO_3$ according to time significantly more increased in the cerebral cortex and decreased in the liver, kidney mercury concentrations compared to the administration of $CH_3HgCl$ only. 2. The combined administration of $CH_3HgCl$ and $Na_2SeO_3$ and pretreatment of $Na_2SeO_3$ increased more succinic dehydrogenase and acetylcholinesterase activities compared to the administration of $CH_3HgCl$ only. Particularly pretreatment of $Na_2SeO_3$ significantly more compared to the administration of $CH_3HgCl$ only. The concentration of adenosine-5'-triphosphate in $Na_2SeO_3$ treatment groups revealed a favourable effect compared to the administration of $CH_3HgCl$ only. 3. Intracellular $Ca^{2+}$ concentration in administration of $CH_3HgCl$ only was increased significantly more than control group in all test hours but was increased significantly more at 48 hours only after treatment in combined administration of $CH_3HgCl$ and $Na_2SeO_3$ and pretreatment of $Na_2SeO_3$ according to time interval more decreased significantly intracellular $Ca^{2+}$ concentration compared to the administration of $CH_3HgCl$ only. 4. Free intrasynaptosomal $Ca^{2+}$ concentration in the combined administration of $CH_3HgCl$ and $Na_2SeO_3$ was decreased ($24%{\sim}40%$) significantly more than the administration of $CH_3HgCl$ only. From the above results, the specific dosage of $Na_2SeO_3$ decreased increment of intracellular $Ca^{2+}$ concentration induced by administration of $CH_3HgCl$. These findings suggest the protective mechanism of $Na_2SeO_3$ on the neurotoxicity of $CH_3HgCl$.

COVID-19 유행이 서울시 초등학교·중학교 교사의 정신건강에 미치는 영향 설문조사

박정수,성현경,고호연,이승환,황건순,신선미,Park, Jeong-Su,Sung, Hyun Kyung,Go, Ho-Yeon,Lee, Seung Hwan,Hwang, Keon Soon,Shin, Seon Mi 대한예방한의학회 2020 대한예방한의학회지 Vol.24 No.3

Objectives : The study aimed to investigate the effect of the COVID-19 epidemic on the mental health of elementary and middle school teachers, especially hwabyung, depression, and anxiety. Methods : The participants were teachers of three elementary schools and one middle school in Seoul. The survey was self-reported by online. The questionnaire included hwabyung scale, CES-D, and GAD-7. Results : The survey conducted from November 5th to December 3rd, 2020. A total number of 81 teachers replied to the survey. The hwabyung prevalence was 27.2% by hwabyung symptoms score. The mean hwabyung characteristics score was 30.10±10.55, the mean hwabyung symptoms score was 18.32±12.26. The depression prevalence was 44.4%, mean CES-D was 15.85±11.51. The anxiety prevalence was 43.2%, mean GAD-7 was 5.05±4.53. Conclusions : The survey showed that teachers had a high score of hwabyung, anxiety, and depression in the COVID-19 epidemic. The teachers were in need of help to improve their mental health.

고장 전류 특성을 고려한 HVDC 적용 방안

박정수,장길수,김찬기,Park, Jung-Soo,Jang, Gil-Soo,Kim, Chan-Ki 한국전기전자학회 2007 전기전자학회논문지 Vol.11 No.4

한국 전력 계통의 가장 큰 문제점은 수도권의 부하 집중으로서, 서울과 경기도를 비롯한 수도권의 부하량은 전체 전력 소비량의 약 40%를 차지하는 반면 이들 지역의 발전량은 전체 전력 발전량의 약 16%에 불과하다. 이러한 수도권의 전력 수급에서의 불균형은 수도권이 아닌 다른 지역에서의 전력 전송을 필요로 한다. 이러한 장거리 전력 전송은 유효 전력에서의 손실 증대, 국지적인 무효 전력 불균형으로 인한 송전 용량 제한, 고장 용량의 증대 등을 일으키게 된다. 이를 해결하기 위해 고려할 수 있는 가장 간단한 방법은 수도권 내의 발전소 신설 또는 대용량 송전 선로의 추가 설치이다. 그러나 수도권은 과도한 인적 물적 자원의 밀집으로 인하여 대규모 발전소 및 송변전 설비의 건설을 위한 토지 조달 등에 어려움이 있고 또한 인구 밀집 지역에서는 공해와 같은 환경적 문제와 혐오 시설 기피 등의 사회적 문제로 인하여 현실적으로 발전소 또는 송 변전 설비의 건설은 불가능한 실정이다. 따라서 대규모 설비의 건설에 의한 문제 해결 보다는 기존 설비의 활용도를 증대시키는 방향으로의 접근법이 요구된다. 본 연구에서는 기존 송전 선로의 활용도 증대를 고려한 HVDC의 적용 방안을 개발하고자 하며, 이를 위한 시뮬레이션 모델의 개발 및 해석을 다루고 있다. One of the most serious problems in KEPCO power system is the load centralization in the capital area. The load capacity in the capital area is almost 40% of the total load. However, the generation capacity in this area is just 16% of the total generation. The inequality, between the power demand and supply, in this area needs the power transmission from other regions. The simplest method to solve the problem is the installation of power plants or the addition of high-capacity transmission line in the metropolitan area. However, because of the concentration of human and material resources, there is a difficulty in the installation of the generation and transformer facility. As a result, instead of the installation of large scale facilities, the approach to maximize the application of existing facilities is required. In this research, we will develop a scheme with an HVDC installation for enhancing power transfer capability by utilizing the existing transmission lines.

천해에서 이동음원으로 측정한 해저면 후방산란의 통계적 특성

박정수,정문섭,장덕홍,최재영,심태보,Park, J.S.,Jurng, M.S.,Chang, D.H.,Choi, J.Y.,Shim, Tae-Bo 한국음향학회 1996 韓國音響學會誌 Vol.15 No.4

산란강도의 변동에 따른 통계적 특성은 능동소나의 성능에 영향을 미칠 뿐만 아니라, 주요 산란과정을 이해하는 측면에서 매우 중요하다. 본 논문에서는 천해에서 측정한 해저면 후방산란 신호의 통계적 특성 분석에 대한 내용을 기술하였다. 천천히 움직이는 30kHz의 실험용 소나로 해저면에 대한 자료를 수집하였다. 신호의 진폭변화에 대한 시${\cdot}$공간 상관함수를 계산하였다. 또한, 넓은 빔과 좁은 빔 신호의 포락선에대한 분포함수와 오경보 확률을 계산하고, 이론 모델과 비교를 시도하였다. 분석 결과에서 이동음원에 의한 해저면 후방산란 변동의 통계적 특성은 고정된 음원의 경우와 다른 특징을 나타냈다. Fluctuation statistics of scattering strength are not only important because they impact the performance of active sonar systems, but also because they may provide insight into the major scattering process. In this article, analysis of the statistical characteristics of bottom backscattering, measured in shallow water, are presented. The slowly moving experimental sonar was operated at 30kHz to gather data over the bottom. Spatial and temporal correlation functions of the signal amplitudes were measured. The distribution function and probability of false alarm function of the detected envelope of widebeam and narrowbeam signals were measured. An attempt was made to compare the results with existing theoretical models. The result suggests that the statistical characteristics of bottom backscattering fluctuation of moving source is differ from that of fixed source.

축척법에 의한 화약 폭풍과 분석

박정수,김성호,이근득,이재민,Park, Jung-Su,Kim, Sung-Ho,Lee, Keun-Deuk,Lee, Jai-Min 한국군사과학기술학회 2005 한국군사과학기술학회지 Vol.8 No.4

To analyze a blast effect of developed explosives, three different kinds of aluminized tastable explosives and melted cast explosive TNT were used. Conventional explosive TNT was used as a reference. Each tested explosive charge of 340mm diameter spherical type was initiated at the charge center with DXD-65(${\sim}750g$) booster and RP-87 EBW detonator. Thirteen piezo type pressure sensors were located at a range from 4 to 50m away from the charge. From the blast wave profiles, we calculated a peak blast pressure and impulse of the explosion. The calculated pressures and in pulses were converted to TNT Equivalent Weight(TEW) factor by the scaling ]aw method. The average TEW factors based on the blast pressure of TX-01, TX-02, TX-03, TX-04 were 1.298, 1.05, 1.266, 1.274 and the average TEW factors based on impulse were 1.504, 1.686, 1.640, 1.679. From the results, we concluded that TEW factors based on blast pressure and based on impulse of aluminized explosives were superior to TNT. This results are owing to the high contents of aluminum in formulations.

한의사 의료기기 사용과 관련된 판례 및 기존 연구 분석과 경향 변화

박정수,오기창,권상혁,추홍민,김정상,Park, Jeongsu,Oh, Kichang,Kwon, Sanghyuk,Chu, Hongmin,Kim, Jungsang 대한한방내과학회 2021 大韓韓方內科學會誌 Vol.42 No.6

Objectives: The aim of this study was to examine the debate on the use of medical devices between Western Medicine and Korean Medicine, as this is one of the greatest conflicts in Korea's medical profession. Judicial precedents and interpretations of authority serve as regulations because medical affairs law states that Korean Medicine practices are ambiguous. Method: We conducted a search in the Korean RISS, OASIS, and DBPIA databases using several keywords associated with medical devices, Korean Medicine, and Korean Medicine Doctors. The search period was until November 5 2021. The retrieved papers were classified according to the selection and exclusion criteria by checking the title, abstract, and text. For precedents, searches were done regarding comprehensive legal information, etc., and in the case of non-disclosure precedents, we requested access to the precedents by web-court requests. Results: A total of 80 documents were found as a result of the search, and 13 publications were included in the study. The selected publications were classified and analyzed by this research team into Korean medicine, Western medicine, and legal or state agency research. In the existing literature and judgments, the arguments that played a major role changed depending on the time the judgment was made. "Social conventions", "curriculum", "academic principles", and "health and hygiene dangers" were the key arguments. Conclusions: Further studies will be needed that can comprehensively arrange the existing literature and clinical results, and continuous study will be needed to verify that the use of medical devices by Korean medicine doctors is helpful for prognosis and accurate treatment of their patients.

모델링기법을 이용한 A₂O 하수처리공정에서 주요 공정관리에 관한 연구

박정수,김성덕,도현승,Park, Jung Soo,Kim, Sung Duk,Seung, Dho Hyon 한국방재안전학회 2020 한국방재안전학회 논문집 Vol.13 No.2

본 연구에서는 A₂O 공정을 적용하여 운영중인 하수처리시설의 운영데이타를 바탕으로 현재 운영중인 하수처리장의 효율성을 통계적기법을 이용하여 분석하였으며, GPS-X 공정모델프로그램을 활용하여 최적의 운영조건을 도출하였다. 하수처리장의 운영인자는 기초통계분석과 상관관계분석, 일원분산분석을 실시하였다. 기초통계 분석결과 연구대상 하수처리장의 유입량은 여름철에 가장 높게 분석되었으며, 다른 계절에 비해서 유입량의 변동성이 가장 크게 나타났다. 다원변량 분석의 결과 유출 T-N 및 NH₄⁺-N은 C/N비와 통계적으로 유의한 수준이 도출되지 않았다(p-value : > 0.05). A₂O하수운영의 각 영향인자중에서 질소 성분의 제거는 유입 수온, HRT, SRT, DO에 주로 영향을 받고, BOD의 경우 모든 운영 인자, COD는 항목은 HRT, SRT, DO 운영인자에 영향을 받았다. GPS-X를 A₂O 공정의 이용한 시뮬레이션에서 매개변수는 최대 침전 속도, 종속영양미생물 수율(무산소성), 인 반포화계수, 종속영양미생물 사멸율, 종속영양미생물 최대 성장률, 독립영양미생물 최대 성장률, 최대 침전 속도로 나타나 이러한 매개변수가 시뮬레이션에 주요 영향을 미치는 인자로 확인되었다. The efficiency of sewage treatment was ananlyzed selecting a sewage treatment plant in Gyeonggi-do where A₂O process was applied. Statistical techniques based on the operation data of the sewage treatment were used. The main factors directly affecting the efficiency of the treatment process were analyzed using a GPS-X model. The correlation analysis and one-way ANOVA were performed. The T-N and NH₄⁺-N values of the effluent did not generate statistically significant level (p-value:>0.05) when compared with C/N ration values. Removel of nitrogen components form sewage treatment plants were affected by temperature, HRT, SRT and DO. In the case of BOD, all operating factors were affected, while COD was affecte by factors of HRT, STR and DO. In simulations using GPS-X, the parameters that greatly influence was included the maximum sedimentation rate, the dependent nutrient microbial yield (anoxic), the phosphorus saturation coefficient, the dependent nutrient microbial killing rate, the dependent nutrient microbial maximum growth rate, and the independent trophic microorganisms. The maximum growth rate and the maximum setting rate were identified.

한의 교의 사업에 대한 학생 만족도 연구

박정수,신선미,고호연,고재언,성현경,Park, Jeong-Su,Shin, Seon Mi,Go, Ho-Yeon,Ko, Jae-Un,Sung, Hyun Kyung 대한한방소아과학회 2018 대한한방소아과학회지 Vol.32 No.1

Objectives It is important to maintain health for students. The School Health Law is enacted in Korea to carry out the school health project like Korean Medicine Doctor's student Health and Wellness program. The purpose of this study was to examine the student's satisfaction of the program. Methods The school project was conducted in 19 schools in Seongnam city from May 2016 to December 2016. This school program was consisted of health counseling, necessary treatment, health related lectures, and vocational education about Korean medicine. A satisfaction questionnaire was conducted to gather information about overall satisfaction of the program and the program details such as health counseling, treatment, and health lectures. Results A total of 1,713 students and faculty members participated and 164 of those students completed the satisfaction survey. The overall mean score for the teaching activities was $8.54{\pm}1.76$, satisfaction of health counseling was $8.57{\pm}1.74$, treatment satisfaction was $8.39{\pm}1.83$, satisfaction with the health lectures was $8.23{\pm}1.96$ (range 3~10), and the need for continuity of the program was $8.43{\pm}1.91$ (range 1~10). One of the main benefit from the program was that students were able to get necessary treatment as soon as possible (51.2%). Conclusions We found that Korean medicine is suitable for the program. However, the large-scale prospective study will be needed for validation of the findings.

구매속성에 따른 기업의 사회적 책임활동이 소비자의 식품 구매의도에 미치는 영향

박정수,심기현,Park, Jung-Soo,Sim, Ki Hyeon 한국식품영양학회 2014 韓國食品營養學會誌 Vol.27 No.5

This study investigated the effects that corporate social responsibility (CSR) had on the credibility and image of a food corporation by analyzing the purchasing intention and food purchases of consumers. This analysis was undertaken in an attempt to establish a marketing strategy that meets consumer demands, and the results showed that all CSR activities undertaken by the food corporation had a positive effect on the reliability and image of the corporation and on consumers' purchase intention. The results indicate that the ethical aspect of the CSR activities had the greatest effect while their charitable aspect had the least effect on the reliability and purchase intention of the customers regarding the food corporation. Thus, it appears that establishing of suitable ethical doctrines and guidelines for corporate management by food corporation is effective in emphasizing the ethical aspects of their policies through transparent management by means of fair trade.

태풍 강수 특성 및 K-water 물 관리 태풍 대응체계 소개

박정수,Park, Jeong-Su 한국수자원학회 2016 물과 미래(한국수자원학회지) Vol.49 No.8