Clinical Characteristics of Auricular Keloids Treated with Surgical Excision

박소영,오정훈,Guen-Ho Lee,Jung Mee Park,Sang-Gyun Jin 대한청각학회 2012 Journal of Audiology & Otology Vol.16 No.3

Background and Objectives: Differences in morphology of auricular keloids possibly contribute to distinct results of treatment. The aim of this study was to evaluate clinical characteristics of the auricular keloids according to the modified Chang-Park classification and to compare the results of treatment including recurrence rate between the subgroups. Subjects and Methods: Clinical data of 15 patients of auricular keloids were retrospectively reviewed. The keloids were classified according to modified Chang-Park classification. Clinical characteristics, the presence of recurrence, and the duration required for the recurrence were compared. Results: Eight out of 15 patients (53.3%) were single sessile type (type II), followed by 4 patients of pedunculated type, 1 patient of multiple sessile type, 1 patient of buried type, and 1 patient of mixed type, respectively. Recurrent keloids after previous surgeries were noted in 7 out of 15 patients and most of them (6 of 7, 85.7%) were sessile type. Three patients who underwent surgery at our department showed recurrence. Conclusions: The classification of auricular keloids according to morphologic patterns can assist surgeons in choosing the appropriate management.

습지생태공원의 갈대확장 조절 기술 개발

성기준 ( Ki June Sung ),이용민 ( Yong Min Yee ),정용현 ( Yong Hyun Chung ),박소영 ( So Young Park ) 한국환경보건기술학회(구 한국환경복원녹화기술학회) 2010 한국환경복원기술학회지 Vol.13 No.5

It is very difficult to control the expansion of reed at a wetland ecological park due to their aggressive reproduction capability. Therefore, proper topography and wetland hydrology should be provided before the construction of a wetland ecological park. Appropriate measures should be taken at the initial stages to prevent reed expansion. Field experiments were conducted at the newly constructed wetland ecological park for 15 months to develop methods to control the reproduction and expansion of Phragmites communis. A complete shading method had the best effect on the prevention of reed reoccurrence among other methods. Complete removal of the rhizomes controlled the reed growth to a greater extent than cutting the aboveground shoots. Water-level manipulation was also better than a half-shading method for the prevention of reed reproduction. These results indicated that soil properties and edge effects can influence the reed growth. Cutting only the aboveground shoots facilitates the growth of reed. These results suggest that reed control should be implemented repeatedly and an alteration in the wetland topography and hydrology may be more effective in the long term. Combination of treatments such as water-level management with shading should be considered to control the growth of reed. Adoptive management for created or restored ecosystem might be considered for accomplishment of its original purpose.

P-28 Autophagy Primes Neutrophils for Neutrophil Extracellular Trap Formation during Sepsis

박소영,( Sanjeeb Shrestha ),( Young-Jin Youn ),( Jun-Kyu Kim ),( Shin-Yeong Kim ),( Hyun Jung Kim ),( So-Hee Park ),( Won-Gyun Ahn ),( Shin Kim ),( Myung Goo Lee ),( Ki-Suck Jung ),( Yong Bum Park ),( Eu 대한결핵 및 호흡기학회 2017 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.124 No.0

Rationale: Neutrophils are key effectors in the host’s immune response to sepsis. Excessive stimulation or dysregulated neutrophil functions are believed to be responsible for sepsis pathogenesis. However, the mechanisms regulating functional plasticity of neutrophils during sepsis have not been fully determined. Objectives: We investigated the role of autophagy in neutrophil functions during sepsis in patients with community-acquired pneumonia. Measurements and Main Results: Neutrophils isolated from patients who survived sepsis showed an increase in autophagy induction, and were primed for NET formation in response to subsequent PMA stimulation. In contrast, neutrophils isolated from patients who did not survive sepsis showed dysregulated autophagy and a decreased response to PMA stimulation. The induction of autophagy primed healthy neutrophils for NET formation and vice versa. In a mouse model of sepsis, the augmentation of autophagy improved survival via a NET-dependent mechanism. Conclusions: These results indicate that neutrophil autophagy primes neutrophils for increased NET formation, which is important for proper neutrophil effector functions during sepsis. Our study provides important insight into the role of autophagy in neutrophils during sepsis.

Doritaenopsis 뿌리배양으로부터 고빈도의 Protocorm-like Body(PLB)형성

박소영,오성래,백기엽,Park, So-Young,Oh, Sung-Rae,Paek, Kee-Yoeup 한국식물생명공학회 2003 식물생명공학회지 Vol.30 No.3

Root cluster section culture, showing high efficient Protocorm-like body (PLB) formation capacity, were established in Doritaenopsis hybrids. Three types of root were obtained from excised shoots in 1/2MS medium containing different concentrations of NAA; \circled1normal roots, \circled2multiple roots and \circled3abnormal root clusters. Those were placed on 1/2MS medium supplemented with 0.5 mg/L thidiazuron for PLB regeneration. PLB regeneration rate was greater in root cluster section cultures (77.8%) compare to normal root tip cultures(30%). Number of PLBs regenerated from root cluster sections were counted over 11 per explant (5.3 per normal root tip).High frequency of PLB regeneration was achieved in root cluster section culture. This result can be used as an efficient method for clonal proliferation of Doritaenopsis hybrids.

대구치의 근심 경사 정도에 따른 치주 상태의 비교 연구

박소영,최승환,이수정,장문택,김형섭,Park, So-Young,Choi, Seoung-Hwan,Lee, Su-Jeong,Chang, Moon-Taek,Kim, Hyung-Seop 대한치주과학회 2002 Journal of Periodontal & Implant Science Vol.32 No.1

The aim of this study was to compare periodontal conditions around mesially tipped molars by a tipping degree. Patients who had been consecutively treated at the Department of Periodontology, Chonbuk National University Hospital from October 1999 to August 2001 were assessed with radiographs taken at their molar regions. Of all molars investigated, 142 molars of 116 patients tipped mesially more than 10 degrees to the line perpendicular to an occlusal plane were selected for the study. The tipped molars were divided into 2 groups with a reference to a tipping degree, i.e., 66 slightly tipped(group 1 : <$30^{\circ}$) and 76 severely tipped molars (group 2 : ${\geq}30^{\circ}$). Probing depth(PD), plaque retention index(PRI) at mesial surfaces of tipped molars and tooth mobility(TM) were recorded at the clinical examination. Tipping degree(TD) and alveolar bony defect(ABD) at the mesial surface of the molars were measured in a radiograph. The results showed that no statistical differences were found between groups in all measured variables. In Pearson correlation analysis performed in the same group, a positive relationship was shown between PRI and PD in the group 1 and, in the group 2, between PRI and PD as well as PRI and ABD(p < 0.01). However, no statistically significant relationship was found between TD and all other variables in both groups. Within limitations of this study, it may be concluded that tipping degree did not seem to influence periodontal conditions, i.e., PD, ABD and TM of mesially tipped molars per se, but plaque presence/absence seemed to mainly affect the periodontal conditions of the tipped molars.

Fructan 생성 S. salivarius의 인공치태 억제효과

박소영,박은혜,오종석,양규호,Park, So-Yung,Park, Eun-Hae,Oh, Jong-Suk,Yang, Kyu-Ho 대한소아치과학회 2003 大韓小兒齒科學會誌 Vol.30 No.1

구강 질환으로 중요한 치아우식증은 구강 세균 중 Streptococcus mutans가 주 원인균이며, 치면에 부착, 증식 및 산생성 과정을 거쳐 치아우식을 유발한다. Streptococcus salivarius는 사람의 구강에 정상적으로 존재하는 세균이다. 본 연구에서는 소아의 구강으로 부터 분리된 9주의 S. salivarius의 특성과 S. mutans 및 Streptococcus oralis에 대한 영향을 연구하여 다음과 같은 결과를 얻었다. 1. 비커 와이어 검사에서 S. mutans 배양시 형성된 인공치태 무게는 204.9 mg이었으나, S. mutans와 분리된 S. salivarius의 혼합 배양시 형성된 인공치태 무게는 1.9 mg에서 20.6 mg으로 S. mutans 단독 배양시와 큰 차이가 있었다(p<0.05). 배양 후 생균수 검사에서는 큰 차이가 없었다. 2. M17 액체배지에서 배양된 분리균주의 배양 상청액을 가한 비커 와이어 검사에서 형성된 인공치태 무게는 평균 117.1 mg인데 반해, 5% 자당이 함유된 M17 액체배지에서 배양된 분리균주 배양 상청액을 가한 비커 와이어 검사에서는 평균 47.7 mg이었다. 3. 분리된 S. salivarius의 배양 상청액을 thin layer chromatography를 실시한 결과, 분리균주가 형성한 중합체는 프럭탄 (fructan)이었다. 4. 비커 와이어 검사에서 프럭탄의 일종인 inulin과 levan 모두 S. mutans의 인공치태 형성을 억제하지 못하였다. 이상의 결과를 종합하면 프럭탄을 생성하는 S. salivarius는 S. mutans의 인공치태 형성을 억제하였다. S. mutans is the most important causative bacteria of dental caries among the oral bacteria. S. salivarius is a normal inhabitant in the human oral cavity. Nine strains of S. salivarius in this study were isolated from the oral cavities of children and identified, and their effect on S. mutans and S. oralis was studied. 1. The mean weight of produced artificial plaque on the wires in the beaker was 204.9 mg in the culture of S. mutans only, whereas being reduced to 1.9 mg through 20.6mg in the combined culture of S. mutans and each S. salivarius isolate (p<0.05). The viable cell didn't show the difference between them after culturing. 2. When S. mutans was cultured in the media containing culture supernatant of each S. salivarius isolate in M17 broth, the mean weight of produced artificial plaque was 117.1 mg on the wires, whereas being 47.7 mg in the media containing culture supernatant of each S. salivarius isolate in M17 broth containing 5% sucrose. 3. The polymer produced by S. salivarius isolates was on the thin layer chromatography. 4. Inulin and levan didn't inhibit the formation of artificial plaque by S. mutans in the beaker test. These results suggested that fructan-producing S. salivarius isolates inhibited the formation of artificial plaque by S. mutans.

F-144 Factors associated with outcome of patient with acute respiratory failure on pumpless extracorporeal interventional lung assist_pilot study

박소영,( Yousang Ko ),( Seung Hyeun Lee ),( Hong Mo Kang ),( Myung Jae Park ),( Yong Bum Park ) 대한결핵 및 호흡기학회 2016 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.121 No.-

Introduction: Pumpless interventional lung assist (iLA) have been advocated in patients suffering from severe acute respiratory failure . However, there is few evidence about factors with outcome of patient with acute respiratory failure using iLA. We evaluated effect and prognostic factor of the iLA in patients with acute respiratory failure Method: We evaluated retrospectively our experience with iLA between March 2013 and August 2016. iLA was implemented patients from multiple etiologies with severe hypercapnea(pH< 7.1 and PCO2 >70mmHg). Laboratory parameters,ventilator parameters, hemodynamic parameter and adverse events were recorded serially. Our primary outcome was ICU mortality. Results: Between March 2013 and August 2016, we enrolled 11 patients with severe respiratory failure, 2 patients had prone pone positioning using iLA and they all survived in ICU. iLA lead to an acute and moderate increase in arterial oxygenation (PaO2/FiO2 ratio 2hr after initiation of iLA (150 ±25 mmHg) compared with pre iLA(110 ± 20.2 mmHg). Hypercapnia was promptly reversed within 2hr (PaCO2, 35.9±12.4 mmHg) in comparison with before (75.9±23.4 mmHg , p < 0.05], which allowed a more protective ventilator strategy. In our study, ICU mortality is 36.4 %, SOFA score and lactate clearance were significantly related with ICU mortality. Conclusions: iLA might provide a sufficient rescue measure with easy handling properties in patients with severe hypercapnic respiratory failure. Also, prone position during iLA is safe and could be improved outcome.

경북 일부지역 중학생의 소금 섭취 관련 행동변화단계에 따른 식행동 조사

박소영,이경아,Park, So-Young,Lee, Kyung-A 한국식품조리과학회 2014 한국식품조리과학회지 Vol.30 No.6

The purpose of this study was to investigate the salt-related dietary behaviors according to the stage of change model in middle school students from the Gyeongsangbuk-do area. Data were collected from, a total of 253 male and 210 female middle school students through. Self-reporting questionnaire. By stage of salt-related dietary behaviors, the 'Pre-contemplation stage' was comprised of 57.3%, the 'Contemplation stage' of 12.2%, the 'Preparation stage' of 7.4% and the 'Action stage' of 23.2% of students. There were significant differences in the stage of change according to the experience with salt-related nutrition education (p<0.05), wherein differences according to gender and parent's education were not observed. In the salt-related dietary behaviors, there were significant differences according to gender (p<0.05), pocket money (p<0.01), and the stage of change (p<0.001). Males had higher salt-related dietary behavior scores than females, while students who had more pocket money also had higher scores, and the action group had lower scores than the other groups. Among the 10 items of salt-related dietary behaviors, only 4 showed above the average score (2.92/5.00), including behaviors of liking kimchi, completely consuming snacks and instant foods, and drinking the broth of soups. The salt-related dietary score of males was higher than females, while the action group's score was lower than the other stages.

SNS를 통한 사회적 관계 형성과 청소년의 삶의 만족

박소영,조성희,Park, So-Young,Cho, Sung-Hui 한국디지털정책학회 2015 디지털융복합연구 Vol.13 No.2

청소년들의 삶의 만족도가 매우 낮은 상황에서 SNS 이용 증가로 인한 사회적 관계 형성은 중요해지고 있다는 인식 하에서 본 연구는 SNS를 통해 형성된 교량적 사회적 자본과 결속적 사회적 자본, 실질적 정치사회 참여가 청소년들의 삶의 만족에 미치는 영향을 살펴보고자 했다. 이를 위해 한국청소년정책연구원이 2012년 실시한 2012년 청소년의 소셜미디어 이용실태 데이터 중 주요변수에 모두 응답한 4,708명의 자료를 최종분석에 사용하였다. 연구결과 여학생에 비해서 남학생의 삶의 만족이 높고, SNS를 통해 형성된 교량적 사회적 자본과 결속적 사회적 자본, 정치사회참여의 수준이 높을수록 삶의 만족이 증가했으며, 세 변수들의 상대적 영향력은 결속적 사회적 자본, 정치사회참여, 교량적 사회적 자본의 순으로 더 큰 영향력을 갖는 것으로 나타났다. 연구결과를 바탕으로 청소년의 삶의 만족도를 증가시키기 위한 논의가 이루어졌다. The degree of adolescents' life satisfaction is very low and the formation of social relationship through SNS is getting important to adolescents. This study aimed to examine if bridging social capital and bonding social capital through SNS and political-social participation affect the life satisfaction of adolescents. Using 2012 Adolescents Social Media Usage Survey of National Youth Policy Institute, this study analyzed 4708 data by Multiple Regression. The results showed that the life satisfaction of male adolescents was higher than that of female adolescents. And the higher the level of bridging social capital and bonding social capital through SNS and political-social participation was, the higher the level of adolescents' life satisfaction. On the basis of the results, practical suggestions to increase the life satisfaction of adolescents were discussed.

산마늘 다신초 증식과 인경형성에 효율적인 생물반응기 배양방식

박소영,이위영,안진권,권영진,박혜진,Park, So-Young,Lee, Wi-Young,Ahn, Jin-Kwon,Kwon, Young-Jin,Park, Hae-Chin 한국식물생명공학회 2004 식물생명공학회지 Vol.31 No.2

본 실험은 산마늘의 산초 증식과 인경 형성에 적합한 생물반응기 배양방식과 인경 형성시 배양방식에 따른 당 대사를 구명하고자 실시되었다. 다신초 증식에는 생물반응기에 망을 걸고 배지에 절편체를 접하게 배양한 RC와 MRC (13-15개)에서 가장 좋은 결과를 얻었다. 인경형성과 비대에는 간헐적으로 배지를 공급해준 E&FS에서 93.4%의 인경형성이 이루어졌고 크기에 있어서도 균일하였다. RC와 MRC에서 형성된 인경은 뿌리가 무성하였으며 인경의 크기도 균일하지 않았다. 배양방식별로 수확한 인경내 유리당 함량은 전반적으로 E&FS.에서 낮았던데 반해 전분 함량은 높았다. 배지내 sucrose, glucose와 fructose는 인경 비대 시기에 감사되었는데 이는 첨가한 sucrose가 가수분해 되기도 전에 glucose나 fructose와 함께 식물체로 바로 이용됨을 보여주는 것이었다. A suitable bioreactor culture system for shoot proliferation and bulblet formation of Allium victorialis var. platyphyllum Makino was established. Uptake of soluble carbohydrates in different bioreactor culture systems was also analyzed during the entire culture period. Optimal conditions for multiple shoot formation were determined in raft culture (RC) and modified raft culture system (MRC) (13-15 per explant) in which the explants were placed on a net contacting liquid medium. For bulblet formation and enlargement, 93.4% of shoot clumps formed bulblets at the basal part. Furthermore, they were uniform in size when cultured with ebb & flood system (E&FS). Bulblets harvested from RC and MRC showed vigorous rooting, however, their growth was not uniform. Whereas soluble carbohydrate contents in the bulblets cultured in E&FS were low, starch content was high. Sucrose, glucose and fructose concentrations in the medium of E&FS culture system decreased as bulblet formation and enlargement proceeded, suggesting that external sucrose is taken up to by the cells before it is hydrolyzed.