組積造 外壁의 熱性能 分析

丘在牛 江原大學校 科學技術硏究所 1986 科學技術硏究 Vol.23 No.1

전기경련요법(Electroconvulsive Therapy)으로 치료한 초조발성 정신분열병(Very Early Onset Schizophrenia) 여아 1례 - 증 례 보 고 -

구재우,이문수,김승현 대한정신약물학회 2005 대한정신약물학회지 Vol.16 No.5

Very early-onset schizophrenia (VEOS) has a very rare prevalence, below 2 in one million children. Electroconvulsive therapy (ECT) is a controversial treatment modality that is only rarely performed on children and adolescents. There is a marked paucity of published data relating to the indications, use, clinical outcome and complications of ECT in this age group We reported a case of ECT in 11-year-old female patient with VEOS who displayed auditory and visual hallucinations, disorganized speech and behavior, and psychomotor agitation. The patient received 19 modified bilateral ECT through intravenous general anesthesia because of the unresponsiveness to risperidone, olanzapine, seroquel and amisulpride. During ECT, she remained on only risperdal 2mg/day. After 15 treatments, there was significant improvement in her psychotic features. After 19 treatments, her psychotic features disappeared and her social activity was much improved. ECT in the management of childhood schizophrenia could be an effective treatment option, especially at the failure of pharmacologic and psychotherapeutic treatment modalities.

한국인 우울 장애 환자에서 Brain-Derived Neurotrophic Factor(BDNF)의 유전자 다형성과 항우울제의 장기 치료 반응

구재우,이화영,백종우,강이헌,이민수,Koo, Jae-Woo,Lee, Hwa-Young,Paik, Jong-Woo,Kang, Rhee-Hun,Lee, Min-Soo 대한생물정신의학회 2006 생물정신의학 Vol.13 No.3

Objective : Since some studies have shown that the brain-derived neurotrophic factor(BDNF) has an important role in the pathophysiology of depression, this study investigated the relationship between BDNF genetic polymorphism and the long-term outcome of the antidepressant treatment. Method : One hundred and eight patients with major depressive disorder were evaluated for the long-term outcome(up to 3 years) of antidepressant treatment. The severity and improvement of depression were assessed with the Clinical Global Impression(CGI) Scale. The genotypes of BDNF 196A/G polymorphism in the patients were determined using Restriction Fragment Length Polymorphism(RFLP). Result : The genotypes of 128 patients were investigated and 95 patients of those have been evaluated for 3 years. No significant differences were noted comparing three-genotype groups for CGI scales at baseline, 4 weeks, 8 weeks, 1 year, 2 years and 3 years. Conclusion : This result shows that BDNF polymorphism investigated in this study was not associated with the long-term outcome of the antidepressant treatment. However, further studies with another BDNF polymorphism should be needed.

무선 자유시점 비디오 스트리밍에서 인기도 기반 전송 기기 선택 기법

구재우(Jae-Woo Koo),조영종(Young-Jong Cho),강경란(Kyungran Kang) 한국통신학회 2016 韓國通信學會論文誌 Vol.41 No.5

무선 디바이스를 이용한 실시간 자유시점 비디오 스트리밍에서 인기도를 기반으로 한 트래픽 감소 기법

구재우(Jae-woo Koo),조영종(Young-jong Cho),강경란(Kyungran Kang) 한국통신학회 2015 한국통신학회 학술대회논문집 Vol.2015 No.11

70 N급 하이드라진 추력기의 촉매대 길이에 따른 압력 불안정 특성

정훈,김종현,구재우,김정수,배대석 한국항공우주학회 2014 한국항공우주학회 학술발표회 논문집 Vol.2014 No.11

70 N급 하이드라진 추력기 개발모델의 압력 불안정 특성 고찰을 위한 지상연소시험을 수행하였다. 순도 99.09 wt%의 단일추진제급 하이드라진이 연소시험용 추진제로 선정되었고, 촉매대에는 이리듐/알루미나 촉매를 충전하였다. 개발모델의 추력실 길이변화가 연소 불안정성에 미치는 영향을 규명하기 위해, 2.79, 2.95, 그리고 3.13 m의 특성길이를 갖는 추력실에 대한 성능평가가 수행되었다. 개발모델에서 4~50 Hz 범위의 저주파 불안정 특성이 발생됨을 관찰하였다. 또, 시험모델에서 발현되는 압력 불안정성은 추력실의 길이변화 보다는 추진제 공급특성에 지배적으로 영향을 받는 것이 확인되었다. A ground hot-firing test (HFT) was performed to make a close examination against the pressure instability for the 70 N-class hydrazine thruster under development. Monopropellant grade hydrazine with 99.09 wt% of purity was adopted as a propellant for the HFT, and catalyst bed was filled with iridium coated granular alumina catalyst. For the investigation into the effects of catalyst-bed length on combustion instability, an evaluation test for the development models (DM) was carried out on three kinds of thrust chambers having the characteristic length of 2.79, 2.95, and 3.13 m. It is confirmed through the test that low frequency instability, which ranges over 4~50 Hz, appears in the DM and the instability of test models are significantly affected by the propellant supply characteristics rather than variation of the chamber length.

조현병 환자의 자살 : 최근 연구결과에 대한 고찰

이호선,이건석,구재우,박선철 대한조현병학회 2015 대한조현병학회지 Vol.18 No.1

The suicide risk of patients with schizophrenia is about 8.5-fold greater than that of the general population. Since 4-13% of patients with schizophrenia commit suicide, and 25-50% attempt suicide at least once during their lifetime, suicide can be a main cause of their higher mortality rate as compared with that of the general population. While evidence suggests that previous depressive disorders, previous suicide attempts, drug misuse, agitation or motor restlessness, fear of mental disintegration, poor adherence to treatment, and recent loss of another person are associated with the increased risk of suicide in schizophrenia, hallucinations have been associated with decreased suicide risk. Despite there being at least modest evidence suggesting that antipsychotics protect against suicidal risk, clozapine has been shown to be the most favorable second-generation antipsychotic for preventing suicide in patients with schizophrenia. In addition, selective serotonin receptor inhibitors can ameliorate suicidal ideation in schizophrenia. Furthermore, individual psychosocial interventions and psychotherapy, and reducing stigma, can be integral strategies for the prevention of suicide in schizophrenia. Further study is needed to identify the epidemiological characteristics and clinical correlates of suicide in Korean patients with schizophrenia, and provide an effective strategy for its prevention in Korea.

주거용 건축물의 소음방지계획에 관한 연구 ( Some Measures of Noise Control for the Urban Residential Building Design )

이경회,김정태,구재우 대한건축학회 1983 建築 Vol.27 No.6

본 연구는 주거용 건축물을 대상으로 현재 서구,일본 한국등의 소음방지 대책을 비교 검토하며 주거용 건축물의 소음방지 계획에 대한 기본적인 대책을 제시하여 건축 실무자들에게 도움을 주고 주거환경의 개선을 도모하는데 그 목적이 있다.

주기성 사지운동증에 따른 수면다원검사 상 수면 변수들의 변화

최종배,최재원,이유진,구재우,정도언,Choi, Jongbae,Choi, Jae-Won,Lee, Yu-Jin,Koo, Jae-Woo,Jeong, Do-Un 대한수면의학회 2017 수면·정신생리 Vol.24 No.1

목 적 : 이 연구에서는 PLMS 지수의 변화에 따라 수면다원검사 상 나타나는 수면 변수들과 주간 졸림 증상의 변화가 있는지 살펴보고, PLMD의 바람직한 진단 기준으로서의 PLMS 지수에 대해 알아보고자 하였다. 방 법 : 총 4195명 환자들에 대해 수면다원검사를 시행한 기록을 조사하여, 17세 이상이고, 원발성 불면증, 수면무호흡증, 기면병, 렘수면 행동장애가 없는 666명의 대상 환자들을 선택하였다. 대상 환자들의 PLMS 지수에 따라 5 이하인 그룹(1 그룹)과, 5에서 15 사이인 그룹(2 그룹), 15를 초과하는 그룹(3그룹)의 세 그룹으로 나누어 비교하였다. 각 그룹별로 연령, 성별, Epworth 졸림 척도, 수면 효율, 입면 후 각성시간, 수면 잠복기, 1단계 수면분율, 2단계 수면분율, 3단계 수면분율, REM 수면분율 등의 변수를 비교하였다. 결 과 : 세 그룹은 연령과 성별에서 통계적으로 의미 있는 차이를 보였다. 수면 효율, WASO, 3단계 수면분율에서 1그룹과 2, 3그룹은 의미 있는 차이를 보였고, 2그룹과 3그룹 사이에는 차이가 없었다. 수면 잠복기와 Epworth 졸림척도에서 1그룹과 3그룹이 의미 있는 차이가 있었고, 2그룹과 3그룹 사이에는 차이가 없었다. 연령을 제어 변수로 설정하고 편상관분석을 실시한 결과 PLMS 지수는 수면 효율, WASO와 의미 있는 상관관계를 나타냈다. 결 론 : 이 연구 결과를 통해 PLMS 지수에 따라 수면다원검사 상 수면 변수의 변화가 있음을 알게 되었다. 또한 변화된 중요 수면 변수에서 2그룹과 3그룹이 차이가 없는 것으로 나타나서, PLMS 지수가 5 이상을 PLMD라고 진단했던 예전 진단 기준을 좀더 옹호하는 결과인 것으로 나타났다. Objectives: Periodic limb movement disorder (PLMD) has been debated with regard to its clinical significance and diagnostic criteria. The current diagnostic criterion for PLMD in adults has been changed from periodic limb movement index (PLMI) > 5/hour to PLMI > 15/hour by the International Classification of Sleep Disorders (ICSD). In this study, we aimed to investigate the changes in polysomnographic sleep variables according to PLMI and to determine the relevance of the diagnostic criterion for PLMD. Methods: Out of 4195 subjects who underwent standard polysomnography, we selected 666 subjects (370 males and 296 females, aged $47.1{\pm}14.8$) who were older than 17 years and were not diagnosed with primary insomnia, sleep apnea, narcolepsy, or REM sleep behavior disorder. Subjects were divided into three groups according to PLMI severity: group 1 ($PLMI{\leq}5$), group 2 (5 < $PLMI{\leq}15$), and group 3 (PLMI > 15). Demographic and polysomnographic sleep variables and Epworth sleepiness scale (ESS) were compared among the three groups. Results: There were significant differences among the three groups in age and gender. Sleep efficiency (SE) and stage 3 sleep percentage in group 1 were significantly higher than those in groups 2 and 3. The wake after sleep onset (WASO) score in group 1 was significantly lower than those in groups 2 and 3. However, there were no significant differences in SE, stage 3 sleep percentage, or WASO between groups 2 and 3. Sleep latency (SL) in group 1 was significantly lower than that in group 3, but there was no difference in SL between group 2 and group 3. ESS score in group 1 was significantly higher than that in group 3, but there was no difference between group 2 and group 3. Partial correlation analysis adjusted by age showed that PLMI was significantly related to SE and WASO. Conclusion: This study suggests that PLMI influences polysomnographic sleep variables. In addition, we found the individuals who did not have PLMD but had PLMI > 5 were not different in polysomnographic sleep variables from the individuals who had PLMD according to the current criterion. These results raise questions about the relevance of the current diagnostic criterion of PLMD.

메탄-공기 예혼합화염의 구조변이에 대한 수치적 연구

최현아(Hyun Ah Choi),구재우(Jae Woo Koo),박재문(Jae Moon Park),배성훈(Seong Hun Bae),김정수(Jeong Soo Kim) 한국추진공학회 2014 한국추진공학회 학술대회논문집 Vol.2014 No.12

본 연구에서는 메탄-공기 예혼합화염을 해석하기 위한 수치해석기법과 해당 기법을 적용하여 전산 모사한 결과로 나타나는 네 가지 화염구조를 제시한다. 해석에는 상용코드 ANSYS-Fluent를 사용하였고 예혼합연소 해석에는 G-equation model을 적용하였다. 해석기법의 타당성 검증을 위해 실험에서 얻은 슐리렌 이미지와 비교하였다. 해석을 통해 점화원에서 생성된 화염이 반구화염, 평면화염 그리고 튤립화염의 순으로 전파되는 것을 확인하였고, 결과를 바탕으로 각각의 화염구조에 대해 분석하였다. A numerical method for the analysis of CH₄-Air premixed flame is presented with the scrutiny into the flame structure and propagation behavior. The continuity, momentum, energy and mass fraction equation with standard k-ε turbulence model were solved with ANSYS-Fluent. It is confirmed with comparison to experimental results that flame structure changes in the order of hemispherical, flat and tulip flame. The detailed analysis on each flame structure is conducted using vectors and contours.