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      • KCI등재

        Blake`s Milton : 계시적 전통과 상상력의 회복 Prophetic Tradition and Renovation of Imagination

        정규환 한국밀턴학회 1993 중세근세영문학 Vol.3 No.-

        Blake, amongst the Romantic poets, is the most self-conscious poet of his being in the mainstream of prophetic tradition. Blake sees the last poet-prophet in Milton, who has succeeded to the legitimate Christ inheriting the line of the prophets of Old Testament. Milton, therefore, is to Blake the greatest poet surpassing even Chaucer and Shakespeare. Blake willingly receives the influence from Milton. The conviction that the prior prophet is not a suppressor but a liberator for the successor underlies his wholehearted acceptance of Milton. Rereading Paradise Lost, he makes Milton through Milton take off the errors done in his intellectual and domestic life. Harold Bloom argues that "strong poets make poetic history by misreading one another, so as to clear imaginative space for themselves." With Blake, however, this is not to the point His attitude toward Milton is never passive submission. Blake's prophetic thinking and insights of man and the world steer clear of Milton's. He criticizes Milton with no reservation. For his trenchant criticism does not aim at Milton the unparalleled poet-prophet; but at his erroneous States-a poet partly eclipsed by the stock models of classical literature, a reactionary with his conservative theology. Hence evolves his revisionist reading of Milton. Blake dedicates himself to the improvement of civilization through rejuvenating human imagination His revolutionary vision derives from the inexhaustible sources of faith in human ability to pass through the trial of the continual self-annihilation, which enlivens humanity stripping it of age-old, worn and hampering wear of values and thoughts. In composing and reading literature Blake finds the most mighty means of renovating human mind and spirit The issues Blake handles in Milton run from psychological dimension to sociopolitical and historical one. Blake's poetic imagination encompassing this multi-dimensional field spreads over the concentric circles, across which waves of alternating direction radiate and converge ceaselessly.

      • KCI등재후보
      • KCI등재후보
      • KCI등재후보

        고용량 131I 투여환자 퇴원이후 환자 간병인과 환자 가옥의 피폭선량 측정

        정규환,이현국,조운갑,이재기 대한방사선과학회 2010 방사선기술과학 Vol.33 No.2

        고용량 방사성요오드 131I 투여환자의 퇴원 이후 환자 가족이나 간병인, 가옥에 대한 외부피폭 방사선량을 개인선량계인 OSL(Optically Stimulated Luminescence dosimeter) 선량계를 사용하여 평가하였다. 3.37~5.55GBq(100~150mCi)의 131I을 투여한 환자가 2박3일 또는 3박4일의 입원 기간이 지난 후 요양을 위하여 가정으로 귀가 한 후부터 5일에서 8일 동안 간병을 담당한 사람이 피폭한 방사선량과 집안 내 주요 지점에서의 누적공간방사선량인 주변선량을 OSL 선량계를 이용하여 측정하였다. 고용량 치료 환자의 가족이나 간병인, 집안 내 주요 지점에서의 누적피폭방사선량은 1mSv의 1/10 수준인 0.1mSv 내외로 측정되어 원자력법에서 정하고 있는 일반인에 대한 선량한도를 초과하지 않는 것으로 평가되었다. 소수의 표본임에도 불구하고 환자 주변인에 대한 측정값의 표준편차가 0.087mSv로 크지 않았음을 볼 때 모집단인 전체 환자가족의 피폭 방사선량도 표본집단의 결과와 큰 차이를 보이지 않을 것으로 유추할 수 있어 환자의 입원 치료기간을 현재보다 단축하는 방안을 추가로 검토하거나 연구할 필요가 있을 것으로 보인다.

      • Running Title: Effects of Preoperative Oral Carbohydrate-rich Solution

        정규환,강기수,김미연,송현주,정유남,한상훈,강민숙,고민조,김소혜,김덕자,김민정,김은정,김지숙,양영미 한국정맥경장영양학회 2017 한국정맥경장영양학회 학술대회집 Vol.2017 No.-

        Background: Bowel preparation in elective colon surgery typically requires two days of diet restriction and administration of laxatives. However, studies now show that this may no longer be a strict protocol for colorectal surgery. Aside from patients experiencing the discomfort of NPO, there are reported benefits regarding intake of liquids until at least two hours prior to surgery such as decrease in insulin resistance, without additional postoperative surgical complications. Purpose: This study aims to show the benefits of oral rehydration solution administration two hours prior to surgery for patients undergoing elective colectomy, particularly postoperative insulin resistance. Methods: This is a randomized controlled trial. All patients undergoing elective colectomy is included and randomized to the control arm or treatment arm. The control arm consists of the standard bowel preparation and one day of NPO, while the treatment arm consists of the standard bowel preparation and allowing carbohydrate-rich oral rehydration solution intake until 2 hours before surgery. The insulin, glucose, cortisol and triglyceride levels is determined right after induction, 6 hours, 24 hours, and 48 hours post-op, and compared. The Homeostatic Model Assessment - Insulin Resistance (HOMA-IR), insulin, glucose, cortisol, and triglyceride levels will be determined and compared between the two groups. Also, pre- and postoperative satisfactions of patients were assessed using questionnaires. Results: Total number of enrolled patients was 77. Of 77 patients, 4 patients have retrieved previous consent and operation schedules of two patients were cancelled. Of 71 patients, samples of ten patients were analyzed incompletely. There was time effect on both groups. However, there was no significant in the difference of HOMA-IR according to groups and time (Repeated-Measure ANOVA) although the graph looked like showing some differences (p=0.516). Cortisol and TG were also not significant, respectively (p=0.706, p=0.241). Patients who had drunk ORS preoperatively have satisfied (p<0.001) Conclusions: Preoperative oral carbohydrate-rich solution had a limited effect on postoperative Insulin-resistance in patients undergoing colectomy. Satisfaction was higher in patients group who had drunk ORS preoperatively.

      • KCI등재

        Comparative analysis of mortality and progression to end-stage renal disease between surgically induced and medical chronic kidney disease: A study using the National Health Insurance customized database

        정규환,박석우,김하성,이정국,정창욱 대한비뇨의학회 2023 Investigative and Clinical Urology Vol.64 No.4

        Purpose: We aimed to compare the mortality rate and the risk for progression to end-stage renal disease (ESRD) and cardiovascular disease (CVD) between patients who underwent surgery for localized renal cell carcinoma (RCC) and those with chronic kidney disease (CKD) without surgery by investigating the National Health Insurance Service. Materials and Methods: The surgical group (CKD-S) included patients who underwent radical or partial nephrectomy for RCC from 2007 to 2009. Grades of surgical CKD were classified according to the estimated glomerular filtration rate (eGFR) measured at a health screening within 2 years after surgery. The nonsurgical group (CKD-M) was graded according to the eGFR in the 2009–2010 health screenings. We performed 1:5 propensity score matching for age, gender, diabetes, hypertension, Charlson comorbidity index, smoking, alcohol consumption, baseline eGFR, and body mass index. Results: A total of 8,698 patients (CKD-S, n=1,521; CKD-M, n=7,177) were analyzed. The CKD-M group was at higher risk for progression to ESRD (hazard ratio [HR] 1.90, 95% confidence interval [CI] 1.04–3.44, p=0.036) and CVD (HR 1.17, 95% CI 1.06–1.29, p=0.002) than the CKD-S group. In the group of patients with grade 3 disease or higher, the CKD-M group was at significantly higher risk for progression to ESRD (HR 2.21, 95% CI 1.47–3.31, p<0.001), CVD (HR 1.32, 95% CI 1.20–1.45, p<0.001), and overall mortality (HR 1.50, 95% CI 1.21–1.86, p<0.001). Conclusions: The risk for progression to ESRD, CVD, or mortality in patients with CKD-S may be lower than in patients with CKD-M.

      • KCI등재

        Endoscopic Botulinum Toxin Injection for Refractory Enuresis Based on Urodynamic Assessment

        정규환,임영재,장관,서준교,박관진 대한배뇨장애요실금학회 2021 International Neurourology Journal Vol.25 No.3

        Purpose: This study aimed to determine the urodynamic characteristics of refractory enuresis and explored whether those characteristics can be managed through differential endoscopic injections with botulinum toxin. Methods: In total, 27 patients with nonmonosymptomatic enuresis who showed no response after conservative treatment for more than 12 months were included. The patients then underwent a videourodynamic study and received a differential endoscopic injection of botulinum toxin on the same day. Reduced capacity, detrusor overactivity, and bladder neck widening were the 3 major abnormal findings assessed during the filling phase, while sphincter hyperactivity was the only abnormality assessed during the emptying phase. An intravesical or intrasphincteric injection of botulinum toxin was attempted according to the videourodynamic study findings. Follow-up was conducted at 1, 3, 6, and 12 months after treatment. Results: The median age was 10 years (range, 7–31 years). Although 19 and 8 patients had a preoperative diagnosis of overactive bladder or dysfunctional voiding, respectively, the urodynamic diagnosis was different in more than half of the patients. Those showing detrusor overactivity benefited from intravesical botulinum toxin injection, whereas those with only sphincter hyperactivity benefited from both intravesical and intrasphincteric injections. Treatment resistance to botulinum toxin seemed to be attributable to bladder neck widening. Time had no apparent effect on efficacy, which persisted 6 months after the injection. More than 80% of the patients maintained the benefits of the injection after 1 year. Conclusions: Videourodynamic studies were useful for identifying the reasons underlying refractory nonmonosymptomatic enuresis and helpful for determining the appropriate site of botulinum toxin injection.

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