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Osteogenic Sarcoma의 소견을 보이는 난소의 원발성 Malignant Mixed Mesodermal Tumor
허만하(MH Huh),박두철(DC Park),하근수(KS Ha),배국환(KH Bae),강대경(DK Kang),정재훈(JH Chung) 대한산부인과학회 1971 Obstetrics & Gynecology Science Vol.14 No.4
난관에 발생한 malignant giant cell tumor와 구별이 불가능한 병변을 특징으로 하는 mixed mesodermal tumor 1예를 보고한다. A case of malignant ovarian mixed mesodermal tumor in a 42 years old Korean female (in a artificial menopause) is presented. The histology of the tumor is unique in that it reveals mesenchymal components histologically indistinguishable from primary osteogenic sarcoma of bone. Discussion and literature review are made in relation to the histogenesis and histopathological features of malignant Mullerian mesodermal tumor or ovary. This reprents the first reported case of malignant mixed mesodermal tumor or ovary in Korean literature.
허만하(Man Ha Huh),이선경(Sun Kyung Lee),설미영(Mee Young Sol),서강석(Kang Suek Suh),장희경(Hee Kyung Chang) 대한소화기학회 1993 대한소화기학회지 Vol.25 No.4
N/A The authors investigated 1,335 cases of colorectal carcinoma which were diagnosed with resected colon and rectum or fiberoptic biopsies from 1971 to 1990 in Pusan area. We analysed them statistically in epidemiological view point and obtained the following results. The time trends indicated that difference in the annual fluctuation of age-adjusted incidence rate of colorectal carcinoma durng last 20 years was statistically significant. In the sex ratio, the male incidence was higher than female ratio in the first term, but the incidences of both sex were similar in later term. The increase rate of the incidence of right colon carcinoma was similar to that of left colon carcinoma. The patient age at diagnosis ranged from 16 to 87 years. The mean was 47.8 (48.4 in male and 51.0 in female) iin first term and 53.0 (52.5 in male and 53.5 in female) in later term. The incidences of colorectal carcinoma in middle aged and old aged patients were increased with the time trend compared with that of young aged. The incidence rates of Dukes A and B in the first term were 4.1% and 17.3%, but those in the later term 4.6% and 35.8%, respectively. The increased rate of incidences of Dukes A and B stages were predominant in the left colon. From the above result, authors concluded that the epidemiological pattern of colorectal carcinoma among Korean in Pusan area showed a transition moving from ENDEMIC pattern to EPIDEMIC pattern of Haenszels epiderniological model for the colorectal carcinoma.
B형 만성활동성간염에 대한 Adenine Arabinoside 및 α - Interferon 의 치료효과
구자영(Ja Young Koo),박병채(Byung Chae Park),허만하(Man Ha Huh),이성숙(Sung Sook Lee),임창범(Chang Bum Lim),편도철(Do Chul Pyun) 대한소화기학회 1989 대한소화기학회지 Vol.21 No.1
N/A To evaluate and compare therapeutic efficacy of adenine arabinoside (Ara-A) and alpha interferon (alpha-INF), 59 patients with biopsy proven chronic active hepatitis B were randomized to receive Ara-A (15 mg/kg/day for 10 days) or alpha-INF (total dose: 108 million units) and followed up 6 months after completion of therapy.All patients were HBeAg positive. Clinical effects of Ara-A and alpha-INF on seroconversion of HBeAg and levels of serum alanine aminotransferase (ALT) were closely matched and compared with those of untreated control group (30 cases). Seroconversion of HBeAg in alpha-INF treated group (30 cases) was observed in 11 cases (36.7%), showing higher seroconversion rate as compared to Ara-A treated (6/29 cases, 20.7%) and to control patients (0/30 cases, 0%). There were no effects of Ara-A on ALT levels in the treated patients as compared with the untreated control patients. However, ALT levels in the interferon treated patients were remarkably (p<0.005, ALT levels at 6 months after treatment: 83.37±98.83 IU/L) reduced as compared with the level of pretreatment level (256.74 ± 175,83 IU/L). The present study, thus, indicates that Ara-A is not recommended as a first choice of therapy in the treatement for the patients with HBeAg positive CAH, but interferon may be recommended for those patients and further study will be necessary with prolonged follow up.
송기명(KM Song),이희동(IS Lee),오세량(SR Oh),허만하(MH Huh) 대한산부인과학회 1973 Obstetrics & Gynecology Science Vol.16 No.4
This is the first case, reported in Korea, of foreign-body granulomatous lesions confirmed clinically and pathologically, following the use of Lipiodol for the (hysterosalpingography), Literature review realted to foreign-body granulomas of the fallopian tubes, following the use of Lipiodol, are carried out.