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문태철(Tae Chul Moon),박정옥(Jeong Ok Park),정광원(Kwang Won Chung),손건호(Keun Ho Son),김현표(Hyun Pyo Kim),강삼식(Sam Sik Kang),장현욱(Hyeun Wook Chang),정규찬(Kyu Charn Chung) 대한약학회 1999 약학회지 Vol.43 No.1
Because of the potent effects of lipid mediators such as Prostaglandins (PGs), leukotriens (LTs) and platelet activating factor (PAF) on a variety of cells and tissues, they are considered as major contributors to the process leading to inflammation and allergy. To pursue the mechanism of anti-inflammatory activity of Lonicera japonica, we tested inhibitory effects of 7 flavonoids from Lonicera japonica on arachidonic acid cascade related enzymes, such as inflammatory phospholipase A2, cyclooxygenase-1 and 2, 5-lipoxygenase, in bone marrow-derived mast cells (BMMC), and lyso PAF- acetyltransferase in rat spleen nicrosomes. Anti-inflammatory activities of Lonicera japonica are thought to be attributed at least in part to the inhibition of arachidonic acid cascade releated enzymes by flavonoids such as apigenin, luteolin and quercetin.
일 종합병원의 간호인력 증원에 따른 입원환자 간호만족도
송충숙,서미숙,남수민,박선혜,오명순,한경화,박정옥,박미미,현명선,Song, Chung-Sook,Seo, Mi-Suk,Nam, Su-Min,Park, Seon-Hye,Oh, Myoung-Sun,Han, Kyeong-Hwa,Park, Jeong-Ok,Park, Mi-Mi,Hyun, Myung-Sun 한국가정간호학회 2009 가정간호학회지 Vol.16 No.2
Purpose: This study was to examine patient satisfaction related to an increase in nursing personnel staffing. Methods: The subjects of this study were 317 hospitalized patients in the general wards of a medical center in Kyungki Do. Data were collected at 2 and 8 months following an increase in nursing personnel in the hospital. Patient Satisfaction Scale developed by Lee(1986) and revised by Seo(2000) was used. The data were analyzed by descriptive analysis, t-test, ${\chi}2$ test, and one way ANOVA. Results: Although the patient satisfaction scores at 8 months were higher than the scores at 2 months, there were no significant differences in patient satisfaction between the two periods Among the patient satisfaction subscales, the scores of the education subscale at 8 months were marginally higher than at 2 months (t=-1.97, p=.050). Conclusions: Adequate nursing staffing is important in patient satisfaction and patient outcome. The results provide data that suggests a positive direction for nursing intervention and development of nursing professionals.
朴貞玉,金箕洪 우석대학교 의과대학 1969 우석의대잡지 Vol.6 No.1
In order to investigate the phagocytic and digestive activities of RES in X-irradiated mice with experimental infection of E. coli, the quantitative cultures of the blood, liver and spleen were carried out. Total number of 420 mice were divided into group 1, 2, 3, 4 and 5, consisting of 60, 70, 90 and 100 mice respectively. Whole body X-irradiation of 200R. in the group 2, 300R. in the group 3, 400R. in the group 4, and 500R. in the group 5, were given and thereafter 0.2ml. (8.4×10^(7)-1×10^(8)) of E. cloi, ATCC-0128, suspension was injected into the tail vein of each mouse 72 hours after irradiation. Seven mice of each group were respectively sacrificed at the 4th hour 1st, 2nd, 3rd, 4th, 5th, 6th, 7th and 8th day after inoculation respectively and quantitative cultures of blood, liver and spleen were carried out. 1. There was definitely high rate of mortality in the groups with X-irradiation comparing to that of non-irradiated group. The mortality rate rose up to 2.7, 3.8 and 4.2 times of non-irradiated group respectively in the group 3, 4 and 5. 2. The mortality rate within the first 4 hours after inoculation was slightly higher than theseafter 4 hours. In the former, most of the mice died immediately after injection. 3. At the 4th hour, the number of bacteria in the blood showed no significant differences between each group, and were rapidly decreased at the first day when bacteremia began to disappear in all but the group 5. The organism was completely disappeared at the 2nd day in the gronp 1 and 2 and at the 3rd day in the group 3,4 and 5. 4. The rate of positive cultures of the liver was roughly parallel to the dose of irradiation. The organism could not be isolated in the group 1 at the 4th day but contineously recovered in some mice of all X-irradiated groups up to the 8th day. 5. The number of viable organism isolated from the hepatic tissue is also roughly in parallel with the dose of irradiation. In all groups, markedly decreased number of organism could be observed at the first day comparing to the 4th hour. The number of organism was markedly increased at the 5th day in the group 2, at the 4, 5 and 6th day in the group 3 and from 2nd to 8th day in the group 4 and 5 in some of the mice which showed positive culture. 6. The rate of positive cultures for the splenic tissue was parallel roughly with the dose of irradiation. The organism was completely disappeared at the 3rd day in the non·irradiated group while at tile 4th day in the irradiated groups. 7. The number of viable organism in the splenic tissue is also roughly parallel with the dote of irradiation. At the first day a remarkable decrease in the number of organism was observed in comparison with that of the 4th hour in all groups and number was contineously decreased there after. In summery, it would appear that the phagocytic actvity of RES to E. coli in the circulating blood is not significantly affected by X-irradiation of less than 500 R. In the liver, the digestive activity seems to be affected considerablely by dose of 200 R or more. Increased number of viable organism in the splenic tissue was observed with the dose of 300 R or more but completely disappeared after the 3rd day. This would suggest that the spleen shows rather rapid recovery of the normal function of RES from X-irradiation impairment,
金銀花(Lonicerae Flos) Ethyl Acetate 分割의 過酸化脂質生成抑制에 關한 硏究
鄭圭燦,朴貞玉,裵基哲,權東烈,白錫煥 영남대학교 자원문제연구소 1990 資源問題硏究 Vol.9 No.-
The inhibitory effects of Lonicerae Flos' fractions ( benzene, CHCl₃, EtOAc and MeOH fraction. respectlvely ) on microsomal lipid peroxidation were comparatively studied and furthermore each components of EtOAc fraction has been examined. It is found that G component of EtOAc fraction inhibited most strongly for lipid peroxidatlon. Among the EtOAc fractions, G component was identified to be luteolin. Also, EtOAc fraction showed particularly strong increment against superoxide dismutase activlty
Flavonoids from the Aerial Parts of Lonicera japonica
Son, Kun Ho,Park, Jung Ok,Chung, Kyu Chan,Chang, Hyeun Wook,Kim, Hyun Pyo,Kim, Ju Sun,Kang, Sam Sik 영남대학교 약품개발연구소 1993 영남대학교 약품개발연구소 연구업적집 Vol.3 No.-
Seven flavonoids were isolated from the aerial parts of Lonicera japonica. Their structures were characterized as hydnocarpin 1, quercetin 2, ochnaflavone 3, ochnaflavone 4'-O-methylether 4, astragalin 5, isoquercitrin 6, and rhoifolin 7 by chemical and spectroscopic evidences.
김종욱,박정옥,김재웅,최영화,이승호 영남대학교 의과대학 1987 Yeungnam University Journal of Medicine Vol.4 No.2
25세 경산부에서 성교후 특별한 원인을 찾을 수 없는, 질후벽중앙부의 열상으로 shock에 빠진 1예와 29세 경산부에서 성교후 질후궁륭부 열상 및 골반복막 일부 열상의 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다. Two cases of vaginal injury due to coitus are presented. One is the case of the laceration of midportion of posterior vaginal wall with shock and the other one is the laceration of posterior vaginal fornix and pelvic peritoneum. They are all in multiparity. And a review of literature on vaginal injury due to coitus is made briefly.
최영하,박정옥,박완석,이태형,이승호 영남대학교 의과대학 1989 Yeungnam University Journal of Medicine Vol.6 No.1
본원 산부인과에서 산전 초음파 검사에 의해 거대 태아 경부 낭종으로 진단, 중절시킨 임신 22주 태아의 부검 결과 낭포성 히그로마로 판명되어 이에 문헌 고찰과 함께 보고하는 바이다. Fetal cystic hygroma is a rare congenital malformation of the lymphatic system appearing as a single or multicolulated fluid-filled cavity, most often in the neck. A case of fetal nuchal cystic hygroma was diagnosed by ultrasonography at 22 weeks of gestation and the diagnosis was confirmed at autopsy. We present the case with a brief review of literature.