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Xanthogranulomatous Appendicitis Mimicking Residual Burkitt’s Lymphoma After Chemotherapy
남수민,강정현,최성은,김유리,백승혁,손승국 대한대장항문학회 2016 Annals of Coloproctolgy Vol.32 No.2
The case of a 23-year-old female treated with aggressive high-dose therapy for Burkitt’s lymphoma is reported. A positron emission tomography and computed tomography scan after completion of chemotherapy revealed a residual hypermetabolic lesion in the right pelvic cavity. A pelvic magnetic resonance imaging scan showed circumferential wall thickening at the tip of the appendix. A laparoscopic exploration and appendectomy were performed, and a pathologic examination of the resected appendix revealed xanthogranulomatous appendicitis. This is a rare case of a xanthogranulomatous appendicitis mimicking remnant Burkitt’s lymphoma after completion of chemotherapy.
Synthesis of Two step Indole Derivatives in a Continuous Flow System
남수민,박찬필 한국공업화학회 2019 한국공업화학회 연구논문 초록집 Vol.2019 No.1
Indole derivatives are used as antibiotics in pharmaceuticals and have various physiological and biological characteristics such as antipyretic, anti-fungal and anti-inflammatory. In this study, the reaction proceeds in two steps. First of all, the first reaction is C3-formylation of indole in the microreactor. As a secondary reaction, the synthesis of Tri(indolyl)methanes(TIM) is carried out by acid catalyst reaction using Indole and Indole-3-carboxyaldehyde synthesized by C3-formylation of Indole. In the case of the first reaction, the microreactor optimized various parameters to obtain 76% yield in 10 minutes. However, the secondary reaction TIM synthesis is difficult to apply to the microreactor because the product is solid. In this study, the problem of solid formation in the Microreactor can be solved by generating product and disperse phase using mineral oil as a carrier phase during synthesis.
Clinicopathologic Analysis of Lateral Margin Measured by Whole-Mount Section in T3 Rectal Cancer
남수민,홍영기,최윤정,Jung Gu Kang 대한대장항문학회 2020 Annals of Coloproctolgy Vol.36 No.3
Purpose: Total mesorectal excision is a standard technique for rectal cancer. The whole-mount section can encompass the entire specimen, so it is a more appropriate for measuring circumferential margin than conventional section. We analyzed the clinical characteristics and prognosis based on lateral margins (LMs) measured by whole-mount sections. Methods: Medical records of patients who were operated on for T3 rectal cancer from 2005 to 2015 were reviewed retrospectively. A total of 154 patients were included. The slides of the whole-mount sections were re-reviewed by a single pathologist. Results: We divided the groups according to the length of the LM (1 mm, 1.5 mm, and 2 mm). There was significantly frequent lymphovascular invasion and N state was higher when LM was short in all groups. There were more micrometastasis in group LM ≤1 mm (53.3% ≤1 mm vs. 26.6% >1 mm, P=0.039), but not in other groups. When looking at local recurrence alone, there was no significant difference between groups, but the 5-year local recurrence-free survival was significantly worse when LM ≤2 mm (P=0.050). In each analysis based on 1 mm and 1.5 mm, overall survival was worse when LM was short. In all groups, disease-specific survival was worse when LM was short. Conclusion: As previously known, securing a margin less than 1 mm negatively affects the prognosis. When LM was divided by 1.5 mm, there was a significant difference in overall survival. There was a significant difference in disease-specific survival when divided by 2 mm in T3 rectal cancer. However, further studies with more patients are necessary to secure the result.
남수민,Dong Wook Kim,Kyu-Won Jung,Yoon Jung Choi,Jung Gu Kang 대한대장항문학회 2020 Annals of Coloproctolgy Vol.36 No.6
Purpose: Although most colorectal malignancies are adenocarcinomas from mucosa, various types of malignant and benign tumors can develop. Due to extremely low incidence, little research has been conducted. The purpose was to assess incidence and compare it according to demographic factors.Methods: Data from the Korea National Cancer Registry from 2007 to 2016 were used. The crude incidence, age-standard incidence rate (ASR) of colorectal nonadenocarcinomas were calculated.Results: Over 11 years, there were 267,142 patients with colorectal malignancies. The patients of 14,495 (5.43%) were diagnosed with nonadenocarcinoma. The ASR was 2.52 per 100,000 in men and 1.56 in women. Lesions were classified according to histologic categories; neuroendocrine tumor (NET) was the most common malignancy (10,919 [75.33%]). Nonadenocarcinoma was the most common in 40s and 50s (40 to 49 years, 3,530 [24.35%]; 50 to 59 years, 3,991 [27.53%]). Lymphoma was high (54.46%) in patients in teenagers. Proportion of NET decreased with age and that of carcinoma increased with age. Carcinoma, sarcoma, and lymphoma were more common among men and melanoma was more common among women. The most common site was the rectum (11,066 [76.34%]). Lymphoma occurred more frequently in proximal colon. Melanoma, gastrointestinal stromal tumor, and NET occurred mostly in rectum. A total of 10,155 patients (70.06%) were classified as having localized disease.Conclusion: This study is meaningful as it is the first study to examine incidence of colorectal nonadenocarcinoma. Differences in incidence of different lesions based on demographic factors were identified. This study will play a role in cancer prevention and diagnosis projects.
일시적인 갑상선중독증을 동반한 소아의 급성 갑상선주위염 1예
남수민,이미영,고장현,성기준,정춘희 대한내분비학회 2006 Endocrinology and metabolism Vol.21 No.2
Acute thyroiditis is a rare disease because of the sufficient supply of blood vessels and lymphatics in thyroid tissue, the high concentration of iodide in the thyroid tissue and the nearly completely isolated structure of the thyroid gland from the surrounding tissue via its capsule. The most common route of infection is from a pyriform sinus fistula and then the inflammation spreads from the sinus to the perithyroidal space. Computed tomography (CT) and magnetic resonance imaging (MRI) can show a low echogenic mass encircling thyroid gland and swelling of the perithyroidal tissue in acute suppurative thyroiditis. We experienced a case of acute perithyroiditis with thyrotoxicosis that developed in a 13-year old boy and he was diagnosed by the CT findings. The patient had complained of a low graded fever and neck swelling. The laboratory diagnosis and clinical course was like that of subacute thyroiditis, but the CT finding showed a show low echogenic mass encircling the thyroid glands and swelling of the perithyroidal tissue. Therefore, we diagnosed this patient with acute perithyroiditis. After treatment with antibiotics, he displayed clinical improvement and was discharged. (J Kor Soc Endocrinol 21:142~145, 2006) 본 환자의 증례는 영상 진단상 갑상선중독증을 동반한 급성 갑상선주위염으로 진단하였으며 이에 문헌고찰과 함께 보고하는 바이다.
LSTM을 활용한 골든크로스 사건 기반 주식 변동률 예측
남수민,김지은,이준기 한국컴퓨터정보학회 2023 韓國컴퓨터情報學會論文誌 Vol.28 No.8
The Golden Cross is commonly seen as a buy signal in financial markets, but its reliability for predicting stock price movements is limited due to market volatility. This paper introduces a time-invariant approach that considers the Golden Cross as a singular event. Utilizing LSTM neural networks, we forecast significant stock price changes following a Golden Cross occurrence. By comparing our approach with traditional time series analysis and using a confusion matrix for classification, we demonstrate its effectiveness in predicting post-event stock price trends. To conclude, this study proposes a model with a precision of 83%. By utilizing the model, investors can alleviate potential losses, rather than making buy decisions under all circumstances following a Golden Cross event.