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옥경선,김광하,박도윤,이현정,전혜경,백동훈,이봉은,송근암 거트앤리버 소화기연관학회협의회 2016 Gut and Liver Vol.10 No.4
Background/Aims: Magnifying endoscopy with narrow band imaging (ME-NBI) is a useful modality for the detailed visualization of microsurface (MS) and microvascular (MV) structures in the gastrointestinal tract. This study aimed to determine whether the MS and MV patterns in ME-NBI differ according to the histologic type, invasion depth, and mucin phenotype of early gastric cancers (EGCs). Methods: The MS and MV patterns of 160 lesions in 160 patients with EGC who underwent ME-NBI before endoscopic or surgical resection were prospectively collected and analyzed. EGCs were categorized as either differentiated or undifferentiated and as either mucosal or submucosal, and their mucin phenotypes were determined via immunohistochemistry of the tumor specimens. Results: Differentiated tumors mainly displayed an oval and/or tubular MS pattern and a fine network or loop MV pattern, whereas undifferentiated tumors mainly displayed an absent MS pattern and a corkscrew MV pattern. The destructive MS pattern was associated with submucosal invasion, and this association was more prominent in the differentiated tumors than in the undifferentiated tumors. MUC5AC expression was increased in lesions with either a papillary or absent MS pattern and a corkscrew MV pattern, whereas MUC6 expression was increased in lesions with a papillary MS pattern and a loop MV pattern. CD10 expression was more frequent in lesions with a fine network MV pattern. Conclusions: ME-NBI can be useful for predicting the histopathology and mucin phenotype of EGCs.
옥경화(Kyung Hwa Ok),김영호(Young Ho Kim) 한국정보과학회 1991 한국정보과학회 학술발표논문집 Vol.18 No.1
본 논문은 기존의 3차원 하이퍼큐브(Hypercube)에 중앙 노드(Center Node)를 추가시킨 계층구조외 하이퍼큐브(HHC)를 제안한다. 제안된 계층 구조는 중앙 노드가 첨가된 3차원 큐브를 기본 큐브로 하여, 차원이 높아짐에 따라 중앙 노드들을 연결하여 이루어진다. 중앙 노드를 제외한 임의의 노드는 외부 간선 (External Edge)를 가지고 있지 않아 모든 노드의 기본 큐브를 벗어난 외부 통신은 중앙노드를 통한다. 제안된 계층 구조의 하이퍼큐브는 통신하드웨어 구성이 기존의 하이퍼큐브보다 간단하고, 계층 구조(Hierarchical Structure)를 이루며, 직경(Diameter)감소의 특성을 보인다.