태권도 옆차기 동작의 우수자와 비우수자간의 운동학적 비교 분석

이호진,한재희,김륜건,홍예은,우상연 순천향대학교 기초과학연구소 2022 순천향자연과학연구 논문집 Vol.28 No.1,2

The purposes of this study were to analyze the kinematic variations between skilled and unskilled individuals and obtain the data needed to improve effective side kick skill in Teakwondo. We used a video analysis program to collect performance time, changes in movement of the center of the body, angle, and angular velocity. The results were as follows : 1) in unskilled cases, side kick motion occurred for more time than in unskilled cases, 2) to make a stronger kick, the skilled group increased the joint speed of the legs and unskilled athletes have smaller angles than experienced athletes. As a result, the total performance time of side kicks was shorter for skilled people and was consistent with other previous studies. The angle of the knee joint and hip joint had a great influence on the side kick.The range of motion of the hip and knee joints should be increased so that the desired hitting point can be quickly reached.

다중 이용시설의 실내 공기 중 휘발성 유기화합물질(VOC)의 농도에 관한 연구

이기한,최여진,김기현 경희대학교 2003 環境硏究 論文集 Vol.12 No.-

As a means to investigate the status of indoo ollution Korea, we collected and analyzedmajor aromatic volatile compound (VOC) from diverse indoor facilities located all across Seoul city. The concentrations of major aromatic VOc inc uding benzene, toluene, ethylbenzene, xylene (commonly called, BTEX), and styrene were measured during the period covering Sept. through Nov. 2003. the results of our study generally indicated that the VOC levels in most indoor facilities are high enough to be distinguished from outdoor environments. Moreover, such pollution was generally dominated by significantly enhanced concentrations of toluene. Powever, it was found that relative dominance of VOC tend to vary greatly among different indoor conditions.

성인 엉덩관절을 이루는 구조에 대한 형태학적 연구

원예연,장준섭,정인혁,한대용,한창동,서진석 아주대학교 의과학연구소 1999 아주의학 Vol.4 No.1

With 77 hip joints of Korean adults available, anatomical study was carried out to clarify morphological variations of the acetabular labrum, the acetabular articular cartilage, the penetrating sites, the purchasing lengths of transacetabular screws including dangerous neurovascular structures, and the theoretical safe space of the acetabular fossa. The results were as follows; 1. The posterior superior region of the acetabulum through which the screw could be inserted more than 50 ㎜ in length was the safest region. However, depending on the insertion angle, the screw could penetrate the psoas muscle with an average 30 ㎜ of intervening space. 2. The average purchasing length of the screws penetrating the mid point (B) of the articular surface which was located on the inferior portion of the line (AB) connecting the anterior superior iliac spine and the center of the acetabulum: the mid points (C and D) of the articular surface which was located on the anterior and posterior portion of the line (CD) perpendicular to the line AB; and the mid point (G) of the articular surface which was located on the posterior inferior portion of the acetabular articular surface, was more than 20 ㎜. The screws penetrating the point "C" had a risk to damage the bladder and the screws penetrating the points "D" and "G" had a risk to endanger gluteal neurovascular bundles. 3. The screw placed in the anterior superior region of the acetabulum could be directed toward the external iliac vessels. The perpendicular bony thickness of this region averaged 13 ㎜. The topographical relationship of the external iliac artery and vein was variable and classified into 6 types. 4. At the center of the acetabulum, the most vulnerable structure was the obturator neurovascular bundle and the average thickness of bone at this point was measured as 6.5 ㎜. 5. The thickness of the compact bone became wider from the inner side to the outer side of the lunate surface. 6. The posterior inferior portion of the acetabular fossa would be a danger area when we used the screws for infernal fixation of the acetabular fracture through the acetabular fossa. 7. The morphological variations of the acetabular labrum which were measured differently at different locations should be considered during reading magnetic resonance images. 8. The anterior, anterosuperior and posterosuperior portion of the acetabular labrum might be easily torn because the labrum was attached to the bone-like "seating on a flat bony surface." 9. The shape of the articular cartilage was classified into 5 types according to the position of both ends. The above data in this study revealed new findings which should be considered at the times of diagnosis and operation of the hip joint together with morphological characteristics of Korean adult hips.

7,12-Dimethylbenz(a)anthracene(DMBA)에 의해 유발된 생쥐 피부종양의 특성

장예진,한상철,김완종 순천향대학교 기초과학연구소 1996 순천향자연과학연구 논문집 Vol.2 No.2

Skin tumor of hairless mouse (Mus musculus) induced by 7,12-dimethylbenz(a)anthracene (DMBA) was observed by light and electron microscopes. On histologic examination, it was revealed that the tumor type was the squamous cell carcinoma. The skin tumor tissue had the thick epidermis and was more keratinized than the case of normal skin. Electron microscopy of the tumor cells, in comparison with normal cells, showed a number of cytoplasmic processes and a cytoplasmic bridge between adjacent cells. Also, the ratio of heterochromatin to euchromatin was high in the tumor cell. There were plentiful free ribosomes and numerous mitochondria in the cytoplasm, suggesting the use of for rapid proliferation. At the dermal-epidermal junction, the basal lamina of tumor cells showed the intermittent discontinuities, through which their cytoplasmic processes penetrate, indicating invasion or metastasis of the tumor cells.

β-Carotene 이 혈중 효소활성도에 미치는 영향

이상한,우기민,조만희,장예진,김창세,김현철 순천향의학연구소 1997 Journal of Soonchunhyang Medical Science Vol.3 No.2

This study was carried out in order to observe the effects of ethanol and β-carotene on the cholesterol, Triglyceride, LDL-cholesterol, HDL-cholesterol, glutathione peroxidase and catalase activities. The normal white S.D rats were classified into 4 group: 0.9% NaCl administration and 20% ethanol administration were referred to as group A, 20% ethanol and 50% β-carotene mixture administration was group B and 50% β-carotene administration was group C for the 30 day-feeding experiment. The results were obtained as following: 1. The blood lipid concentration was most highly increased in group A, was almost normal in group B, but significantly decreased in goup C. 2. The blood antioxidant enzyme activities were significantly decreased in group A, but significantly increased in goup B and C. 3. The blood β-carotene concentration were significantly decreased in group A, and slightly decreased in group B. Surprisingly it was increased in group C.

인간의 혈장아포지단백 A-I에 특이성을 지닌 단일클론항체 A-I30의 light chain의 가변부위를 coding하는 cDNA의 클로님

이상한,우기민,조만희,장예진,김창세,김정경 순천향의학연구소 1997 Journal of Soonchunhyang Medical Science Vol.3 No.2

I prepared a monoclonal antibody (mAb) A-l30 to HDL apolipoprotein A-l with the ultimate goals of expressing the valuable immunodiagnostic single-chain Fv (scFv) in Escherichia coli. The binding specificity of mAb A-l30 was determined by Western blot analysis. From the hybridoma cell line secreting mAb A-l30, poly(A)+ RNA was prepared and used as a template for cDNA synthesis and cloning. The nucleotide sequence analyses revealed that the variable regions of the heavy and light chains were members of mouse heavy chain subgroup ⅡA and κ light chain subgroup Ⅱ, respectively. Comparison of the nucleotide sequences with mouse immunoglobulin genes listed in the GenBank data base showed that the cDNAs have not been previously reported.

사람의 혈장 아포지단백질 A-I에 대한 단일클론항체 A-I4-18의 생성 및 특성 분석

장예진,이상한,김동연,조만희,우기민 순천향의학연구소 1998 Journal of Soonchunhyang Medical Science Vol.4 No.1

본 연구는 사람의 고밀도 지단백질을 구성하는 아포지단백질 A-I에 특이적인 single-chain Fv를 클로닝하여 대장균 세포에서 발현시킬 목적으로, 먼저 단일클론항체 A-I4-18을 제조하였으며 이항체의 특성을 분석하였다. 아포지단백질 A-I을 BALB/c 생쥐에 면역한후 얻어진 비장세포를 Sp2/O myeloma세포주와 융합한 후 융합세포를 생쥐의 복강내에 주입하였으며, 복수를 채취하여 protein A Sepharose CL-4B크로마토그래피법으로 단일클론항체를 분리하였다. Isotyping결과 heavy chain은 subgroup IIa이며 κ형의 light chain을 나타내었으며 항원과의 결합특이성은 ELISA와 Western blotting법으로 확인하였다. Indirect ELISA법으로 얻어진 해리상수 (Kd)값은 8.33x10의 마이너스8승이었다.

Thermoplasma acidophilum의 20S Proteasome에 의한 ATPase-활성적 단백질분해에 관한 연구

우기민,장예진,조만희,김창세,김완종,조성호,이상한 순천향의학연구소 1999 Journal of Soonchunhyang Medical Science Vol.5 No.1

The eukaryotic 26S proteasome is an ATP/ubiquitin-dependent proteolytic complex consisting of the 20S core particle and 19S ATPase complex. However, because of its complexity and unstable properties, this study was carried out to present more simple and stable model for the ATP-activated proteolytic complex in prokaryotes which can take the place of the eukaryotic 26S proteasome. For this purpose, recombinant Thermoplasma 20S proteasome (T20S) and Methanococcus MS4, a sequence homolog of one ATPase subunit in the 19S ATPase complex, were successfully isolated from Escherichia coli (E. coli). The α and β subunits of T20S expressed in E. coli could assemble for themselves, and showed the peptide-hydrolyzing activity. Whereas both T20S and R20S (the 20S complex from rabbit skeletal muscle) had the highest peptidase activity against Suc-LLVY-AMC, a good substrate for chymotrypsin-like peptidase activity, the specific activity of T20S was slightly lower than that of R20S. In addition, several reagents such as KCI, SDS, and ovalbumin were shown to have different effects on the peptidase activities between T20S and R20S. When the ATPase activity of the purified MS4 were assayed , the Km for ATP was about 0.5 mM, and casein could stimulate the activity more than 2 fold without the change in Km. This result implicates that protein-activated ATPase may induce the conformational change of casein, and therefore suggests that MS4 ATPase may activate the proteolytic activity of the 20S proteasome via accelerating the recognition and translocation of the protein substrates.

‘숙명역사관’뮤지엄 아이덴티티 개선을 위한 마케팅, 디자인 전략 수립 -특별 기획전, 홍보, 기프트 샵을 중심으로-

박민지,박한빛,서예원,이진민,장미정,이성애 숙명여자대학교 산업디자인연구소 2017 숙명디자인학 연구 Vol.24 No.-

본 연구는 디자인과 마케팅이 이분법적으로 나누어질 수 없음을 인식하고, 디자인과 마케팅을 융합하여 스페이스 디자인 마케팅을 통한 뮤지엄아이덴티티를 구축하는 일련의 프로세스를 제안하는데 목적이 있다. 본 연구는 2017년 3월~6월 총 15주간 숙명여자대학교 환경디자인과 ‘브랜드·스페이스·마케팅’수업에 서 진행된 결과물로서 작업물을 정리하였다. 본 연구의 범위는 4개(物, 事, 人, 場)의 주제 중, 장소(場)를 중심으로 ‘숙명역사관’의 그래픽, 제품, 공간을 개발하는 브랜드 매뉴얼과 연관하여 한정한다. 이에 본 연구는 ‘숙명역사관’이 가지고 있는 역사적 컨텐츠와 가치를 통해 현재 상황과 문제점을 분석하였다. 그 결과 ‘숙명역사관’의 다양한 마케팅 전략을 제시하고 이에 따른 디자인 전략과 해결 방안을 통해 디자인과 마케팅의 융합을 꾀하였다. 아울러 SWOT 분석을 통해 로고, 명함부터 새로 기획하는 숙명역사관 기프트샵, 인테리어디자인, 디스플레이, 공간연출과 그 안의 제품디자인에 이르기까지 일관성과 통일성을 추구했다. 끝으로 본 연구는 뮤지엄아이덴티티 구축을 위한 창의적 디자인 프로세스를 고찰하며, 이를 바탕으로 개발 매뉴얼을 총체적으로 정리함에 있어서 뮤지엄 브랜딩의 기초 자료로 활용될 것으로 기대된다.

알코올 및 베타 카로틴이 혈액 성분에 미치는 영향에 관한 연구

조만희,우기민,김창세,장예진,이상한,조성호 순천향의학연구소 1997 Journal of Soonchunhyang Medical Science Vol.3 No.2

Human take in many kinds of foods, and also are exposed to various chemicals which may be harmful. Especially, some food and chemicals may give rise to free radicals during metabolism in the tissues. These free radicals, such as superoxide. hydroxy radical and hydrogen peroxide, induce oxidations of the macromolecules, which can cause a variety of damages in the body. But human have anti-oxidative mechanisms well developed against these damages. Anti-oxidants such as vitamines A, C, E, and β-carotene are believed to have a major role in these mechanisms acting as a cofactor of anti-oxidative system. On the basis that alcohol is one of the most common chemicals that induce oxidative damages in liver, this study was carried out to elucidate biochemical changes of blood after alcohol administration as well as to investigate the effects of β-carotene on the alcohol-injected Sprague-Dawley rats. The following results were obtained from this study. At first, the number of WBC after one week were lowest in the alcohol-treated group. But, β-carotene treatment by oral injection was shown to diminish the increasing rate of WBC in the alcohol-treated group. Second, RBC was increased all the time in all groups tested with alcohol and/or β-carotene. It is of interest that there was a sudden increase of RBC in the alcohol-treated group. Third, Hb was increased in the alcohol-treated groups on the second week. On the other hand, the groups of β-carotene treatment showed more higher rate of increase in Ht and MCV. It is of note worthy that these effects were maximized in the group of β-carotene treatment followed by diet with cheese for a week. Finally, alcohol had little or no effect on MCH and MCHC, although β-carotene showed atypical effects. These results made it clear that alcohol can cause damages in liver, resulting in inflammation and increase of RBC. Also β-carotene is believed to protect liver from oxidative effects by alcohol. In according to these results, it is suggested that diet of anti-oxidants such as Vt. A, B, C, E, and β-carotene is strongly recommended to prevent certain diseases caused by oxidative damages.