퍼지 제어기를 이용한 차량의 자율주차 시뮬레이션

박재현,김승철,한창훈,박종오,임영도 東亞大學校 附設 情報通信硏究所 1998 情報通信硏究所論文誌 Vol.6 No.1

In a case of driving beginnners, it is very difficult to park a car perfectly because driver's knowledge makes more errors than intelligent mechanism when they are performed repeatedly. However skilled drivers be of experienced knowledge are able to park a car quickly. In this paper, we analyzed driving patterns of skilled drivers, designed the fuzzy controller to park based on it, and perform auto-parking simulation of a car using that controller.

Enhanced Maturation and Function of Dendritic Cells Using Hydrogel Coated Plate and Antigen Electroporation

Son, Cheol-Hun,Bae, Jae-Ho,Shin, Dong Yeok,Lee, Hong-Rae,Choi, Yung Hyun,Yang, Kwangmo,Park, You-Soo Informa Healthcare 2013 Immunological investigations Vol.42 No.4

<P>Dendritic cells (DCs) are potent antigen-presenting cells that can be matured <I>in vitro</I> from immature dendritic cells (iDCs) in the presence of several biological agents such as cytokine cocktail, CD40L, TNF-a and antigen loading, which are necessary and achieved using various protocols, such as lipofection, passive pulse or electroporation. However, these DCs maturation protocols may cause with a significant loss of cells because of cellular attachment and spreading during culturing. Some biomaterials that influence adhesion and development of cells have been used in cell culture techniques, and it was thought that they might be applied on the culture of DCs. In this study, we used polyHEMA, which is a hydrogel coating biomaterial that prevents DCs from adherence, and investigated whether hydrogel coating affects the maturation of iDCs. The efficiency in the generation of mDCs was improved through hydrogel coating procedure and a dendritic cell maturation marker, CD83, was significantly increased in hydrogel-coated culture condition. The antigen-loaded mDCs from electroporation were further expressed the CD83. The mDCs generated in the hydrogel-coated culture condition showed more, longer and thicker dendrites, and produced more amounts of cytokines such as IL-12 and IFN-γ. Therefore, it was suggested that the hydrogel-coated culture condition could improve function of mDCs.<fn><P>Cheol-Hun Son and Jae-Ho Bae contributed equally to this work.</P></fn></P>

Elevational Distribution of Breeding Bird Communities in Seoraksan National Park, Korea

( Hyun-su Hwang ),( Jae-kang Lee ),( Tae-kyung Eom ),( Ho-kyoung Bae ),( Dong-ho Lee ),( Jong-hwan Lim ),( Sung-cheol Jung ),( Chan-ryul Park ),( Shin-jae Rhim ) 한국산림과학회(구 한국임학회) 2020 한국산림과학회지 Vol.109 No.1

In this study, the elevational distribution of breeding birds in Seoraksan National Park, Korea was investigated. Forty-six species of birds were documented from line transect surveys taken from Seorakdong at 230 m above sea level (a.s.l.) to the Daechungbong summit at 1708 m asl. Birdspecies richness and diversity were highest in Seorakdong and lowest at the Daechungbong summit. As elevation increased, bird species richness and diversity decreased, with a humped-shape trend being observed between 700 m and 1200 m a.s.l. Stepwise analyses revealed that breeding bird species diversity indices were significantly negatively correlated with elevation (r² = 0.327, P < 0.001) and positively correlated with vegetational coverage (r² = 0.324, P = 0.046). Higher elevations supported fewer birds than low and intermediate elevations. Projections at the local scale, including data on behavior and habitat use by birds, will be necessary for optimal conservation and management of the bird communities in Seoraksan National Park.

Elevational Distribution of Breeding Bird Communities in Seoraksan National Park, Korea

Hwang, Hyun-Su,Lee, Jae-Kang,Eom, Tae-Kyung,Bae, Ho-Kyoung,Lee, Dong-Ho,Lim, Jong-Hwan,Jung, Sung-Cheol,Park, Chan-Ryul,Rhim, Shin-Jae Korean Society of Forest Science 2020 한국산림과학회지 Vol.109 No.1

In this study, the elevational distribution of breeding birds in Seoraksan National Park, Korea was investigated. Forty-six species of birds were documented from line transect surveys taken from Seorakdong at 230 m above sea level (a.s.l.) to the Daechungbong summit at 1708 m asl. Birdspecies richness and diversity were highest in Seorakdong and lowest at the Daechungbong summit. As elevation increased, bird species richness and diversity decreased, with a humped-shape trend being observed between 700 m and 1200 m a.s.l. Stepwise analyses revealed that breeding bird species diversity indices were significantly negatively correlated with elevation (r² = 0.327, P < 0.001) and positively correlated with vegetational coverage (r² = 0.324, P = 0.046). Higher elevations supported fewer birds than low and intermediate elevations. Projections at the local scale, including data on behavior and habitat use by birds, will be necessary for optimal conservation and management of the bird communities in Seoraksan National Park.

Distribution of the Fairy Pitta (Pitta nympha) in the South Korea: A focus on protected areas

Gil-Pyo Hong(홍길표),Jae-Hoon Kim(김재훈),Seul-Gi Seo(서슬기),So-Yeon Cho(조소연),Bo-Yeon Hwang(황보연),Jong-Hyun Park(박종현),Seung-Yeon Lee(이승연),Ga-Young Kim(김가영),Wan-Hee Nam(남완희),Ha-Cheol Sung(성하철) 한국조류학회 2021 한국조류학회지 Vol.28 No.2

국내 팔색조(Pitta nympha) 분포 현황을 알아보고자 전국 국립공원 등 보호지역 중심으로 총 19개 지역을 조사하였고, 전문가 네트워크를 통해 자료를 보강하였다. 전국 19개 지역을 조사한 결과 북한산, 지리산 등 내륙지역 7개 국립공원에서는 팔색조가 확인되지 않았고, 경남 거제, 남해, 해남, 장흥 고흥 등 남해안과 인접한 12개 지역에서 팔색조 서식이 확인되었다. 또한 전문가 네트워크를 통해 수집한 팔색조 출현 위치 정보 82건을 분석한 결과, 전국 8개 광역지자체 모두 팔색조 서식이 확인되었고, 내륙지역(26.8%)보다 해안지역(73.2%)에서 더 많이 출현하였다. 연구 결과를 종합해보면, 우리나라의 팔색조는 주로 제주도와 남해안 지역을 중심으로 많이 분포하며, 그 보다 적은 개체수가 내륙 지역에 넓게 분포하고 있는 것으로 나타났다. The present study investigated the current distribution of Fairy Pitta (Pitta nympha) in South Korea. A total of 19 study areas, including protected areas such as national and provincial parks in South Korea were surveyed, and additional data obtained from an expert network. According to the results, Fairy Pitta was absent in seven inland national parks, including Mt. Bukhan and Chiri parks. Fairy Pitta inhabited 12 areas near the southern coast of South Korea, including Geoje, Namhae, Haenam, Jangheung, Goheung, and Gyeongnam Province. The analysis results of 82 datasets obtained from experts with regard to the locations where Fairy Pitta have been spotted showed that the bird inhabits all the eight metropolitan regions in South Korea, and is more frequently spotted in coastal areas (73.2%) than in inland areas (26.8%). The findings demonstrate that Fairy Pitta is mainly distributed in Jeju Island and the southern coast of South Korea, and is distributed in inland areas at relatively lower numbers.

급성 심근경색후 생존심근 진단에서 Dobutamine 심초음파도와 Thallium 심근스캔의 정확성 비교

이근,강덕현,송재관,이철환,최기준,홍명기,김재중,박성욱,박종훈,박승정 대한순환기학회 1998 Korean Circulation Journal Vol.28 No.2

진폐진행정도에 따른 혈청내 구리와 아연 농도의 변동

박정래,박종욱,이수일,이철호,오차재,김창원,조병만,김돈균 大韓産業醫學會 2000 대한직업환경의학회지 Vol.12 No.3

목 적 : 진폐증은 분진으로 인해 인체의 면역기전이 작용하여 폐섬유화가 진행되는 질환으로, 인체의 면역기전에 작용하는 구리와 아연은 진폐증의 병리적인 진행과정인 폐섬유화에 관여한다. 본 연구의 목적은 초기진폐증 유소견자와 진행된 진폐증 환자의 혈청 구리와 아연의 농도를 정상인과 비교함으로써 체내 구리와 아연의 농도가 진폐증의 섬유화의 진행정도에 따라 변동함을 밝히고, 이를 이용하여 폐섬유화의 진행정도를 추정할 수 있는 지표를 제시하고자 한다. 방 법 : 진폐정밀기관에 내원한 초진내 원자 100명과 진폐요양기관에 입원한 진폐증 환자 100명을 선정한 후 흥부사진소견을 ILO 분류법의 진폐진행정도에 따라 각각 세 군(Stage Vl, V2, V3 & Stage Pl, P2, P3)으로 구분한 후 각 군의 혈청구리와 아연의 농도를 비교분석하였다. 대조군으로는 폐결핵, 심근경색, 뇌경색을 경험한 적이 없는 일반인 100명을 선정하였다. 결 과 : 초진내 원자군의 혈청 구리농도는 섬유화의 진행단계에 따른 유의한 차이를 보였으며, Stage V3에서 가장 높았다. 입원환자군에서는 혈청 구리농도가 대조군과 유의한 차이를 보이지 않는데 (p=0, 152), 이는 입원환자의 불량한 영양상태와 건강상태 때문인 것으로 추정된다. 초진내원자군과 입원환자군의 혈청 아연농도는 섬유화의 진행에 따라 통계적인 차이를 보였으며, Stage V2와 Stage P2, P3에서 각각 대조군에 비해 유의하게 낮았다. 혈청 아연과 구리농도의 비또한 양군에서 섬유화의 진행에 따라 의미있게 높았는데, 섬유화가 현저히 진행된 단계 (Stage V3, Stage P2, P3)에서 대조군과 의미있는 차이를 보였다. 결 론 : 초진내 원자와 입원환자의 혈청 Cu/zrl 비는 섬유화의 진행정도가 현저할수록 대조군에 비해 유의하게 높게 나타났다. 진폐증 환자들의 혈청 Cu/zn 비는 진폐증의 폐섬유화의 진행정도를 추정함에 있어 상당히 유용한 지표로 이용될 수 있으며, 폐섬유화의 진행과정에서의 혈청 구리와 아연의 작용기전을 이용한 치료방법의 마련에도 도움이 될 것으로 판단한다. Objectives : Copper and Zinc, the trace elements of a living body, take a part in immunologic mechanism and induce the pulmonary fibrosis which is the pathologic progress of pneumoconiosis. This study was performed to assist the identification of the pathologic process of pulmonary fibrosis in pneumoconiosis. Methods : The subjects of thls study was 200 diagnosed persons as pneumoconiosis, of whom 700 persons was the visitors in the outpatients departments of pneumoconiosis and 100 admissive pneumoconiosis patients. The serum copper and zinc are measured and compared. Results : The mean serum copper concentration of visitor group was significantly higher than that of control group, and that of stage V3 subgroup of visitor group was highest because of their advanced fibrosis. But, there was not the difference of serum copper concentration between patient and control group. We thought that the reason was poor nutritional and health status of the patient. The mean of serum zinc concentration of visitor and patient control was lower than that of control group. As the degree of pulmonary fibrosis was more severe from stage Vl, V2, V3 of visitor to stage Pl, P2, P3 of patient, the mean of serum zinc concentration was lower. The ratio of serum copper/zinc of visitor and patient was higher than that of control, and that of patient was higher than that of visitor. Those results showed that the ratio of serum copper/zlnc ratio more greatly expressed the degree of progression of pneumoconiosis than only copper or zinc concentration by adjustment of nutritional and health status of the patient. Conclusions : As above study results, the degree of pulmonary fibrosis of pneumoconiosis could be estimated by means of serum copper/zinc ratio.

신경교세포 및 RAW 264.7 세포에서 Protein kinase의 활성에 의한 유도성 Nitric oxide synthase의 발현

박상철,노삼길,배소현,박지선,이충재,허강민,석정호,이재흔 충남대학교 의학연구소 2003 충남의대잡지 Vol.30 No.2

NO(nitric oxide) plays an important role as neurotransmitter or cytokine, and pathologic factor for some diseases by the large amount production with iNOS(inducible NO synthase) expression in macrophages or glial cells. The expression of iNOS is regulated by various cytokines, protein kinases and transcription factors. In this experiment, to investigate the roles of progein kinase and NF-kB for iNOS expression, the effects of PMA(phorbol 12-myristate 13-acetate), cAMP, and various protein kinase inhibitors on LPS(lipopolysaccharide)-induced iNOS mRNAN expression and nuclear NF-kB binding complex were examined in C6 glial cells and RAW 264.7 cells. In C6 glial cells, iNOS mRNA expression by LPS was induced from 1 hour and peak at 3 hour after treatment. In RAW 264.7 cells, the mRNA was observed from 3 hour and peak at 6 hour. PMA enhanced markedly LPS-induced iNOS mRNA expression and NF-kB binding complex in C6 glial cells, but did not much influence on LPS-induced iNOS mRNA expression in RAW 264.7 cells, in spite of increased LPS-induced NF-kB binding complex at 30 min. cAMP(dibutyryl cAMP) did not much influence on LPS-induced iNOS mRNA expression, by increased LPS-induced NF-kB binding complex in C6 glial cells. However, in RAW 264.7 cells, cAMP increased slightly LPS-induced iNOS mRNA expression without change of NF-kB binding complex. Staurosporine did not influence on LPS-induced iNOS mRNA expression and NF-kB binding complex in C6 glial cells, but in RAW 264.7 cells, decreased LPS-induced iNOS mRNA expression and NF-kB binding complex. Ro-31-8220 did not much influence on LPS-induced iNOS mRNA expression and NF-kB binding complex in C6 glial cells, but in RAW 264.7 cells, decreased significantly LPS-induced iNOS mRNA expression in spite of increased LPS-induced NF-kB binding complex for 3hours. G 6976 did not much influence on LPS-induced iNOS mRNA expression with decreased NF-kB binding complex in C6 glial cells, but in RAW 264.7 cells, decreased iNOS mRNA expression without influence on LPS-induced NF-kB binding complex. Genistein did not influence on LPS-induced iNOS mRNA expression and NF-kB binding complex in C6 glial cells, but in RAW 264.7 cells, decreased LPS-induced iNOS mRNA expression inspite of increased NF-kB binding complex. These results suggest that LPS-induced regulation of iNOS expression or NF-kB activity in C6 glial cells, might be different from RAW 264.7 cells through various protein kinases or other factors.

최소분산 프로세서를 사용한 정합장 처리에서 신호단편 수에 따른 바이어스의 영향

박재은,신기철,김재수 韓國海洋大學校 附設 海洋科學技術硏究所 2001 硏究論文集 Vol.10 No.2

적응 정합장처리에서 어레이의 센서 수보다 부족한 신호단편 수로 표본 공분산 행렬을 구성할 경우 행렬 계수의 부족으로 행렬의 역변환에 문제가 발생된다. 이를 해결하기 위해 표본 공분산행렬의 대각성분에 일정한 값을 더하거나 고유분해와 같은 기법을 사용하나, 그 결과로 프로세서 출력에서는 바이어스가 발생된다. 본 논문은 고정음원에서 신호단편의 수에 따른 적응 프로세서 출력의 바이어스와 음원 위치 추정결과를 고찰하기 위해 표본 공분산행렬의 대각성분에 일정한 값을 첨가하는 방법으로 최소분산 기법을 사용하여 수치실험과 실측 자료를 분석하였다. 그 결과 센서 수보다 많은 신호단편을 사용하는 것이 바이어스가 적으며, 음원 위치 추정에서도 좋은 성능을 보였다. When using a sample covariance matrix data in paucity of snapshots, adaptive matched field processing will have problem in inverting covariance matrix due to the rank deficiency. The general solutions are diagonal loading and eigenanalysis methods, but there is a significant bias in the power output. This paper presents a quantitative study of bias of power output and the performance of source localization through the simulation and the measured data analysis in fixed source case using the diagonal loading method for the minimum variance processor. Results show that the bias in power output is reduced and the performance of source localization is improved when the number of snapshots is greater than the number of array sensors.

해조류 에탄올 농도별 추출물의 항돌연변이원성 및 항균성

박제석,오명철,오창경,현재석,김봉오,김수현 濟州大學校工科大學産業技術硏究所 1996 尖端技術硏究所論文集 Vol.7 No.2

톳. 미역 및 다시마의 에탄올 농도별 추출물이 MMS. ICR191 및 sodium azide에 의해 유도되는 돌연변이원성의 억제효과 및 E. coli, B. subtilis 및 S. serevisiae에 대한 항균효과를 검정하였다. 톳의 90% 에탄올 추출물은 MMS와 ICR191에 대한 항돌연변이 원성이 각각 70 및 95% 이상으로 매우 높았으나, sodium azide에 대한 항돌연변이원성은 없었다. 미역의 에탄올 농도별 추출물은 30∼90% 에탄올 추출물에서 50% 이상의 항돌연변이 효과를 보았으나 MMS와 sodium azide에 대한 항돌연변이 효과는 없었다. 다시마의 30∼90% 에탄올 추출물의 ICR191에 대한 항돌연변이 효과는 70% 이상이었으나, MMS와 sodium azide에 대한 효과는 없었다. 에탄올 농도별 톳의 추출물들에 대한 항균성 검색 결과 70과 90% 추출물들이 E. coli와 B. subtilis에 대하여 뚜렷한 항균효과는 미역 추출물 보다 다시마의 추출물이 더욱 요과적이었다. 미역 추출물은 50% 추출물만이 S. cerevisiae에 대한 성장저지효과를 나타낸 반면, 다시마 추출물은 90% 에탄올 추출물에서는 시험된 모든 공시균주에 대하여, 그리고 70% 에탄올 추출물에서는 E. coli와 B. sutilis에 대하여 높은 성장저지효과를 나타내었다. Desmutagenic against MMS-, ICR191- and sodium azide-induced mutations, and antimicrobial effects against Escherichia coli, Bacillus subtilis and Saccharomyces cerevisiae by the extracts from Hizikia fusiforme. Laminaria japonica and Undaria pinnatifida with ethanol of a different concentrations were investigated. Desmutagenic effects against MMS and ICR191 of 90% ethanol extracts from Hizikia fusiforme were up 70 and 95%. respectively. no against sodium azide. Desmutagenic effects against ICR191 of 30∼90% ethanol extracts from Undaria pinnatifida and Laminaria japonica were up to 50 and 70%. respectively. but no against sodium azide and MMS. Antimicrobial effect of 70 and 90% ethanol extracts from Hizikia fusiforme had potent antimicrobial activities against E. coli and B. subtilis. Ethanol extracts from Laminaria japonica showed more effective antimicrobial effects than those from Undaria pinnatifida. Only 50% ethanol extract from Undaria pinnatifida showed growth inhibition effect against S. cerevisiae. Seventy percent ethanol extract from Laminaria japonica showed growth inhibition effect against all strains tested. while 90% ethanol extract showed against E. coli and B. subtilis.