곰쓸개 복용 후 발생한 육안적 혈뇨와 신유두부 괴사증 1예

김우진,한민석,김수항,박인형,박진석,선제형,홍세인,박옥영,신정현,이숭,신병철 朝鮮大學校 附設 醫學硏究所 2006 The Medical Journal of Chosun University Vol.31 No.3

Renal papillary necrosis occurs most commonly in association with urinary tract infection, diabetes mellitus, sickle cell disease, vascular disease, and analgesic nephropathy. Clinical presentation may be related to symptoms of pyelonephritis such as flank pain, renal colic, hematuria, Proteinuria, recurrent fever. The necrotic tissue may be sloughed off, and the diagnosis can sometimes be made by finding piece of renal medullary tissue in the urine. Pyelography may demonstrate cavities and sinuses in the resion of papillae. Anuria & oliguria can lead to the acute renal failure, and especially prognosis and progress may be affect influenced by urinary infection. We report a case of renal papillary necrosis with ingestion of bear gallbladder. On pyelography, Persistent contrast is diagnostic clue of renal papillary necrosis. This case is not be related to urinary tract infection, but occurred acute renal failure. Expectant treatment was gone.

광주광역시 치매의 유병률과 위험인자의 도시-농촌 지역 비교

신일선,김재민,윤진상,김석재,양수진,김웅장,이승현,강순아,곽지영,이형영 大韓神經精神醫學會 2002 신경정신의학 Vol.41 No.6

연구목적 : 본 연구의 목적은 광주광역시의 도시 및 농촌 지역에 거주하는 노인에서 치매의 유병률과 위험인자를 조사하고자 하였다. 부가적으로 이 두 지역간에 치매의 유병률과 위험인자를 비교하고자 하였다. 방 법 : 광주광역시의 전형적인 도시와 농촌지역의 65세 이상의 노인(N=1,598)을 대상으로, 2단계의 역학연구를 수행하였다. 1차 선별 단계에서는 38명의 훈련된 연구보조원이 대상노인을 면담하여, 사회인구학적 특징을 조사하고 한국판 간이정신상태검사(Korean version of Mini-Mental State Examination ; MMSE-K)로 평가하였다. 2차 임상 진단 단계에서는 1차 단계에서 MMSE-K 점수가 24점 이하인 노인(N=431)을 대상으로, 전문연구팀의 임상적 평가를 통해 치매를 진단하고 원인질환별로 알쯔하이머병(Alzheimer's disease ; AD), 혈관성 치매(vascular dementia ; VaD) 및 기타 치매로 분류하였다. 대상노인에서 치매의 유병률을 측정한 후, 광주광역시 전체 노인의 연령보정 유병률을 산출하였다. 전체 대상에서 AD의 위험인자를 조사한 후, 도시와 농촌군으로 나누어 분석을 다시 시행하였다. 결 과 : 1차 및 2차 단계의 참가율은 각각 71.0%(N=1,134) 및 83.2%(N=410) 였다. 연구 참여 노인(N=1,134)에서 전체 치매, AD 및 VaD의 유병률은 최소 각각 9.7%, 5.2%, 1.8%였다. 광주광역시 전체 노인의 연령 보정 유병률은 각각 10.7%, 5.7%, 1.9%인 것으로 산출되었다. AD의 독립 위험인자는 고령, 여성, 무학이었다. 도시와 농촌에 따른 유병률의 차이는 파악되지 않았다. 그러나 AD의 위험인자는 지역에 따라 차이가 있었다. 도시 노인에게는 무학만이, 농촌 노인에게는 고령과 여성인 경우가 독립 위험인자였다. 결 론 : 광주광역시 노인에서 치매의 유병률은 높았고, 이는 국내 다른 지역에서 수행된 선행연구 결과와 유사하였다. 알쯔하이머형 치매의 위험인자는 도시와 농촌에 따라 다른 결과를 보였다. 본 연구 결과는 한국에서의 치매의 실태를 반영하며, 치매의 적절한 관리와 예방을 위해서는 지역성 특성이 고려되어야 함을 시사한다. Objectives : The purpose of this study was to investigate the prevalence rate and risk factors of dementia in an urban and a rural sample of older persons in the metropolitan Kwangju area, Republic of Korea. In addition, the prevalence rate and risk factors of dementia between the two samples were compared. Methods : A two-phase epidemiological study of residents aged 65 or over(N=1,598) was conducted in a highly developed, urban and a non-contiguous, poorly developed, rural area of metropolitan Kwangju. In the first(screening) phase, 38 trained research assistants collectively peformed in-home interviews for all participants. Detailed sociodemographic characteristics were gathered and the Korean version of Mini-Mental State Examination (MMSE-K) was administered. In the second (diagnosing) phase, diagnosis of dementia was established for those scoring 24 or less on the MMSE-K in the screening phase(N=431), and etiological types of dementia were classified to Alzheimer's disease(AD), vascular dementia(VaD) or miscellanous type by two teams of experts. Prevalence rate of dementia was determined in the participants, and age-standardized prevalence rate adjusted by age distribution in metropolitan Kwangju was estimated. For AD, the risk factors were investigated in all participants, and analyses were repeated for the urban and rural samples separately. Results : The participating rates in the first and second phases were 71.0%(N=1,134) and 83.2%(N=410), respectively. In the participants, the prevalence rates of dementia(all types), AD and VaD were 9.7%, 5.2% and 1.8%, respectively. The age-standardized prevalence rates were 10.7%, 5.7% and 1.9%, respectively. Aging, female gender and no education(complete lack of formal education) were identified as independent risk factors for AD. No difference between the urban and rural samples was observed in the prevalence rates of dementia(all types), AD and YaD. However, risk factors for AD differed between these areas. In the urban sample, no education was the only significant factor ; whereas, aging and female gender were identified as risk factors in the rural sample. Conclusion : A high prevalence rate of dementia was observed among old persons in metropolitan Kwangju, consistent with previous studies conducted in other Korean areas. The risk factor profi1es for AD differed between urban and rural settings. The results of this study reflect the current status of dementia in Korea and suggests that appropriate management and prevention strategies for dementia should be tailored toward the geographic settings.

악성 거대 난소 점액성 종양 1예

신형도,박형진,김홍곤,한원철 圓光大學校 醫科學硏究所 1999 圓光醫科學 Vol.15 No.1

Mucinous tumor are cystic tumors with loculus lined with mucin-secreting epithelium constitute approximately 8-10% of primary epithelial ovarian tumors. Of all mucinous neoplasms, 75-85% are benign. It is often reach very large size particularly with the benign counterpart being reported on occasion to have exceed 100 lbs. Malignancy develops in 5-10% of benign mucinous cysts. About 15-20% of neoplasms are bilateral. We experienced a huge ovarian mucinous tumor of 155 ㎏. measured 42 × 30 × 28 ㎝ in size, and the volume of cystic contents was about 10 L in a nulligravida 36-year-old woman. Pathologic diagnosis was moderately differentiated mucinous cystadenocarcinoma of right ovary. So, we presented with a brief review of literatures.

악성 신경교종에서 기관형적 배양후 형성된 미세종양 구상체의 초미세구조적연구

신형진,정천기,박인성,정영섭,정희원,한대희 대한신경외과학회 1993 Journal of Korean neurosurgical society Vol.22 No.3

The present study investigated not only the feasibility of organotypic spheroid culture system taken from human malignant gliomas but also the similarities and differences between surgical specimens and cultured spheroids using light microscopy electron microscopy, and flow cytometric examination. Surgically resected tumor specimens from eighteen human malignant gliomas were minced and explanted into agarose-coated culture wells. After three to five days these microtumor fragments emerged as spheroids and could be maintained as organotypic spheroids for more than eight weeks. Measurements of the spheroids showed that they decreased during the initial two to three weeks and afterwards remained unaltered over a specific period of time. This growth pattern of the spheroids was consistent with the condition of tumors in vivo suggesting the linkage of cell proliferation and loss. Light microscopic and electron microscopic studies of the spheroids demonstrated that morphological structures were similar to those of the original tumor tissue in vivo and histopathologic characteristics of the original tumor were maintained over a long culture period. The spheroids contained connective tissues, blood vessels, macrophages and neutrophils maintaining a three-dimensional architectural resemblance to the original tumors. Of three pairs of the surgical and spheroid specimen examined by the flow cytometry, one showed a change of ploidy pattern and two contained increased fictions of proliferating cells. It is concluded that this microtumor spheroid system can maintain the characteristics of the original tumors and may serve as an alternative to the in vivo xenograft model for the research of brain tumor biology, invasion and immunology while providing a valuable technique for the evaluation of new therapies such as biological response modifiers.

무다짐 콘크리트 製造方法에 관한 實驗的 硏究 : 普通强度 領域의 노출콘크리트 壁體를 中心으로 Focused on the Normal Strength Range for Exposed concrete Wall

신형존,정채진 국립7개대학공동논문집간행위원회 2004 공업기술연구 Vol.4 No.-

The construction technique of exposed concrete wall without any defect has known one of the difficult task to the engineers who worked in the civil and building construction field. For this reason, the self compacting concrete technique has been widely applied especially for the very thine concrete wall construction. The objective of this study is to provide the reference date on the manufacturing method for self compacting concrete which has self compacting capability without segregation. The mixing proportion tests for flowing concrete which uses superplasticizer are carried out using W/C ratio between 55~44% which represents the normal compressive strength range 210~280kgf/cm². The experiment results show as follows. 1. Within the normal compressive strength range, the suitable W/C ratio was under 45% in the case of only superplasticizer used for the manufacturing self compacting concrete. 2. The suitable slump flow range was 60cm ± 5cm in the case of the W/C ratio 44%. 3. The suitable S/A ratio was 46% in term of flow and compressive strength in the case of the W/C ratio 44%. 4. There is a little difference between vibrating compaction and self compacting method in term of compressive strength.

OP-1을 투여한 동종이식과 혈관 분포된 조직을 이용한 주 골연골의 재건

신영진,신유식,김형수 大韓成形外科學會 2001 Archives of Plastic Surgery Vol.28 No.3

Sr· 페라이트의 자기특성에 미치는 Al₂O₃의 영향에 관한 연구

신용진,서강수,정병두,김형진 明知大學校 産業技術硏究所 1991 産業技術硏究所論文集 Vol.10 No.-

In this thesis, We have measured the effect of Al₂O₃ to the magnetic properties of Sr-ferrite. The specimens have been composed of SrO and Fe₂O₃. Ratios of 1:5.4 to 1:5.8 have been chosen for SrO and Fe₂O₃. As additives, We used 1wt%, 2 wt% and 3 wt% of Al₂O₃. Sintering was carried out at 1250℃ . From experiments on the magnetic properites of specimen, the results are as follows; 1) For SrO : Fe₂Op3 = 1 : 5.4 and 1 : 5.8, we got similar coercivity and residual flux density, but for 1 : 5.6, decrease sharply. 2) For the additive Al₂O₃, coercivity is increased and residual flux density is decreased with Al₂O₃ respectively. Good basic composition region of nonstoichiometric Sr-ferrite has been appeared on the n=5.4 and n=5.8, but in the case of Al₂O₃ addition, We have confirmed good magnetic properties on the n=5.8.

苛性소다 處理에 依한 밀짚의 飼料價値 增進 硏究

辛炯泰,金贊昊,金鍾奭,宋永祿,林泰鎭 成均館大學校 1982 論文集 Vol.32 No.-

Nylon bag dry matter digestibility (NBDMD, %), nylon bag organic matter digestibility (NBOMD, %) and chemical compositions were analysed to evaluate the nutritive values of 5 varieties of NaOH-treated wheat straws (Jangkwang, Wonkwang, Suwon 210, Suwon 211, Naemil) by using Korean native male goats. Three grams of dried samples by grinding with 2.45㎜ Wiley mill screen were put into a bag 9×14㎠ made of 100 mesh nylon. These bags were put into the ventral sac of the rumen and taken out at the end of 72 hours. They were washed, dried in an oven at 105℃ for 24 hours and weighed “NBDMD” (%) and ashed in an muffle furnace at 600℃ or 24 hours and weighed “NBOMD”(%). The results which were obtained with this experiment were as follows: 1. Nylon bag dry matter digestibility (NBDMD, %) and nylon bag organic matter digestibility (NBOMD, %) of NaOH-treated wheat straws were highly significant different (p<0.01) in different levels of NaOH treatment and of different varieties of wheat straws. 2. The relationship between total mean NBDMD (%, Y_1) of 5 varieties of wheat straws and NaOH concentration (%, X) at 72 hours rumen incubation was: Y_1=34.57+3.56X(r=0.92^**) 3. The relationship between total mean MBOMD (%, Y_2) of 5 varieties of wheat straws and NaOH concentration (%, X) at 72 hours rumen incubation was: Y_2=32.02+2.46X(r=0.92^**) 4. The orders of NBDMD(%) and NBOMD(%) for 5 varieties of wheat straws were Suwon 210, Suwon 211, Naemil, Jangkwang, Wonkwang and Suwon 211, Suwon 210, Naemil, Jangkwang, Wonkwang, respectively. 5. The optimum level of NaOH for improving NBDMD(%) from 5 varieties of wheat straws, on the basis of Blaxter et al. (1961), was 6% NaOH.

대뇌실질에 발생한 포도낭미충증 -증례 보고-

김상진,김진용,박상근,고원규,신형식,황용순 대한신경외과학회 1999 Journal of Korean neurosurgical society Vol.28 No.9

쇼트볼의 형상이 피로수명에 미치는 영향

신용승,정성균,강진식,김태형 서울産業大學校 2000 논문집 Vol.51 No.2

To improve fatigue properties, usually the shot peening process is used in the industrial world. In order to achieve optimum, repeatable and reliable shot peening process, the important shot peening parameters must be controlled. The first item needed to achieve high quality shot peening is to keep shot balls in a good quality. This paper discusses of shape of commonly used shot ball. Also, discussed is shot ball Shape's effect of Fatigue Life.