Reliability Considerations of Hybrid Power Systems for Critical Facilities

Choi, Se Jin · Ham, Young Hwan · Kim, Myung Chin 충북대학교 컴퓨터정보통신연구소 2008 컴퓨터정보통신연구 Vol.27 No.2

본문참고

강원도산 참당귀와 일본산 일당귀의 생리 활성 성분 탐색

함문선,김성수,홍종수,이진하,정을권,박영식,이현용 한국미생물생명공학회 ( 구 한국산업미생물학회 ) 1996 한국미생물·생명공학회지 Vol.24 No.5

참당귀와 일당귀를 에탄올로 추출하였고 이들 추출물들을 디에틸 에테르층과 물층으로 분획하였다. 두 개의 분획물들은 Ames mutagenicity test에서 MNNG(0.5 ㎍/plate)에 대한 강한 항돌연변이 효과를 나타내었다. 디에틸 에테르 분획물들은 MNNG의 돌연변이원성을 78%에서 80%까지 억제시켜 가장 강한 돌연변이 유발 억제효과를 보여주었다. 각각의 에탄올 추출물(1㎍/㎕)들은 사람의 다양한 암세포들의 성장을 억제시켰다. 특히, 디에틸 에테르 분획물들은 간암 세포의 생육을 90%에서 95%까지 억제시켜 가장 강한 항암효과를 보여주었다. 그러나 수층 분획물들은 암세포의 생육에 대하여 거의 억제활성을 나타내지 않았다. 에탄올 추출물들은 인체의 정상 간세포에 대하여 거의 세포독성을 나타내지 않았다. 참당귀의 디에틸 에테르 분획물들은 일당귀와 비교하여 20% 미만의 세포독성을 보여주었다. 참당귀와 일당귀 디에틸 에테르 분획물들의 0.5㎍/㎕ 첨가는 T세포와 B세포의 생육의 3~4배 정도 증가에 의한 면역활성을 보여주었다. 또한 참당귀의 디에틸 에테르 분획물(0.7㎍/㎕)이 ACE 활성을 98%까지 억제시켜 혈압을 조절할 수 있음도 증명되었다. TLC로부터, 두 개의 디에틸 에테르 분획물들은 참당귀와 일당귀의 활성 성분중의 하나로 알려진 umbelliferon을 함유함을 알 수 있었다. The ethanol extracts from Anglica gigas Nakai and Angelica acutiloba Kitagawa were fractionated to diethyl ether and aqueous partitions. Both partitions had strong antimutagenic effect on the MNNG (N-methyl-N-nitro-N-nitrosoguanidine) by Ames mutagenicity of MNNG with inhibition of 78~80%. The ethanol extracts from both species showed the inhibitory effect on the growth of several human cancer cell lines. Especially, the diethyl ether fraction from ethanol extracts was most effective on human hepatocellular carcinoma cells, inhibiting 90~95% of cell growth. However, the aqueous fractions had least inhibition activity on many cancer cells. There was little cytotoxicity on human normal liver cell by ethanol extracts. Diethyl ether fraction from Angelica gigas Nakai ethanol extract had cytotoxicity les than 20% on human normal liver cells, compared with that from Angelica acutiloba Kitagawa ethanol exract. The adding of 0.5 (g/ℓ) of diethyl ether fractions of Angelica gigas Nakai or Angelica acutiloba Kitagawa increased immune activity by enhacing human B and T cells up to three to four times. It was proven that diethyl ether fraction (0.7 g/ℓ) from Angelica gigas Nakai could control blood pressure by suppressing angiotensin converting enzyme activity up to 98%. From TLC, it was appeared that both of diethyl ether partitions had umbelliferon, known to one of active substances from Angelica gigas Nakai and Angelica acutiloba Kitagawa.

成犬의 象兒質 酸腐蝕이 齒隨에 미치는 影響

咸普慧,金永進 慶北大學校 齒科大學 1987 慶北齒大論文集 Vol.4 No.1

The purpose of this study was to evaluate the effect of 37% orthophosphoric acid on dog's dental pulp when the acid was applied to exposed dentin. The experimental group was that the 37% orthophosphoric acid was applied to the dentin exposed by cavity preparation for 60, 90 seconds, and copalite and zinc phosphate cement were placed as temporary restorations. The control group received the same treatment, except saline solution instead of acid has placed on exposed dentin. The specimens were routinely prepared and stained by Hematoxylin-Eosin. The results of this study were as follows: The vacuolization, derangement of odontoblastic layer under prepared cavity and no definite formation of secondary dentin without definite difference in each interval was observed at the control group. The formation of secondary dentin and thickening of the predentin were prominent in 60 sec. acid etching at 5 weeks, but were observed in 90 sec. acid etching group at 8 weeks. Severe hemorrhage and reticular degeneration were observed in both 60 sec. and 90 sec. etching group at the early stage, but recovered gradually with the fibrous pupal tissue according to time elapse.

구강점막에 발생한 섬유성 과증식의 처치

함선영,송창규,박세희,김진우,조경모 大韓齒科保存學會 2009 Restorative Dentistry & Endodontics Vol.34 No.4

구강점막은 흡입되거나 압력을 받아, 병적이진 않으나 임상적으로 뚜렷한 변화를 일으키는 수많은 상황에 놓이게 된다. 협점막과 혀는 치아가 상실되었거나 여분의 공간이 존재하는 부위에서 돌기가 형성될 수 있다. 점막이 여분의 공간으로 압력을 받거나 흡입되어 섬유성 과증식이 발생하게 되는 것이다. 이번 증례보고에서는 구강점막의 섬유성 과증식의 처치에 대해 기술하고자 한다. 섬유성 과증식은 구강점막에 가해진 습관성 압력이나 흡입에 의해 형성될 수 있다. 섬유성 과증식의 치료는 단순 절제술과 원인을 제거하는 것이다. 또한 습관 조절이 재발을 방지하기 위한 중요한 요소가 된다. There are a number of situations where the oral mucosa can be sucked or pressed to produce relatively banal but clinical distinctive changes. The labial and buccal mucosa and tongue may develop protuberances in areas where a tooth is missing or extra space is present. The mucosa is pressed and sucked into theses paces, thus leading to the development of a fibrous hyperplasia. This case report describes the management of fibrous hyperplasia in oral mucosa. Fibrous hyperplasia can be formed by habitual pressure or suction in oral mucosa. Treatment of fibrous hyperplasia consists of simple excision and, if feasible, elimination of the cause. And habit control is a important factor for preventing recurrence.

운동 유발성 횡문근 융해를 동반한 요로결석 2례

허진,최원혁,조진혁,함영희,홍정범,정성규,김현,허동 고신대학교 의과대학 2010 고신대학교 의과대학 학술지 Vol.25 No.2

Two men were admitted to hospital with flank pain, hematuria, which was diagnosised as ureteral stone. Elevation of aspartate aminotransferase (AST) without typical pattern of toxic hepatitis was observed. Careful history taking, several laboratory tests, abdominal and pelvis computered tomography was done. Findings from theses examinations supported the clinical diagnosis of ureteral stone complicated of exercised induced rabdomyolysis. Early recognization of rhabdomyolysis in clinical setting is important, because clinical manifestations have ranged from asymtomatic elevation of creatine kinase to acute renal failure which is a life threating medical emergency. Authors report two cases of exercised induced rhabdomyolysis initially admittied as ureteral stone managed with hydration

몇가지 사시나무속 수종 수피의 추출성분

함연호,배영수,김진규,이상극 한국목재공학회 2002 목재공학 Vol.30 No.1

사시나무속의 현사시, 이태리포플러 및 양황철나무 수피를 아세톤-물(7:3)로 추출한 후 농축하고 헥산, 클로로포름, 에틸아세테이트 및 수용성으로 분획하여 동결건조하였다. 각 추출물은 메탄올 수용액 및 에탄올-헥산 혼합액을 사용하여 Sephadex LH-20 칼럼크로마토그래피로 화합물을 분리한 후 TBA 및 6% 초산으로 전개하는 셀룰로오스 박층크로마토그래피로 단리 여부를 확인하였다. 단리된 화합물의 구조는 ^1H, ^l3C 및 2D-NMR과 질량분석에 의하여 결정되었다. 사시나무속 수종의 추출성분은 주로 flavonoid와 salicin 파생물로 구성되어 있으며 세 종류의 수종에서 모두 15개의 화합물이 분리되었다. 현사시나무에서는 (+)-catechin, naringenin, eriodictyol, sakuranetin, aromadendrin, taxifolin, sakuranetin-5-O-β-D-glucopyranoside, neosaturanin, p-coumaric acid, salireposide와 aesculin이 단리되어 가장 많은 종류의 화합물을 포함하고 있었으며 이태리포플러에서는 (+)-catechin, salireposide, populoside와 salicortin이, 양황철나무에서는 (+)-catechin, padmatin, quercetin, salireposide, populoside와 salicortin이 단리되었다. The bark of P. alba ×glandulosa, P. euramericana and P. nigra ×maximowiczii F_1, several Populus trees, were collected, extracted with acetone-H_2O(7:3, v/v), fractionated with hexane, chloroform and ethylacetate, and freeze dried to give some dark brown powder. Each fraction of the powder was chromatographed on a Sephadex LH-20 column using a series of aqueous methanol and ethanol-hexane mixture as eluents and then identified by thin layer chromatography using TBA and 6% acetic acid as developing solvents. The structures of the isolated compounds were characterized by ^1H, ^13C and 2D-NMR tools including mass spectrometry. Most of the compounds were flavonoids and salicin derivatives as follows: (+)-catechin, taxifolin, aromadendrin, eriodictyol, naringenin, sakuranetin, sakuranetin-5-O-β-D-glucopyranoside, neosaturanin, salireposide, p-coumaric acid, and aesculin from P. alba ×glandulosa, (+)-catechin, salireposide, populoside and salicortin from P. euramericana and (+)-catechin, quercetin, padmatin, salireposide, populoside and salicortin from P. nigra ×maximowiczii F_1.

Resilon을 이용한 근관충전 시 레진계열의 근관실러와 자가-접착 레진시멘트에 따른 미세누출

함선영,김진우,신혜진,조경모,박세희 大韓齒科保存學會 2008 Restorative Dentistry & Endodontics Vol.33 No.3

The purpose of this study was to compare the apical microleakage in root canal filled with Resilon by methacrylate-based root canal sealer or 2 different self-adhesive resin cements. Seventy single-rooted extracted human teeth were sectioned at the CEJ perpendicular to the long axis of the roots with diamond disk. Canal preparation was performed with crown-down technique using Profile NiTi rotary instruments and GG drill. Each canal was prepared to ISO size 40, .04 taper and 1 ㎜ short from the apex. The prepared roots were randomly divided into 4 experimental groups of 15 roots each and 5 roots each for positive and negative control group. The root canals were filled by lateral condensation as follows. Group 1: Gutta-percha with AH-26, Group 2: Resilon with RealSeal primer & sealer, Group 3: Resilon with Rely-X Unicem, Group 4: Resilon with BisCem. After stored in 37℃, 100% humidity chamber for 7 days, the roots were coated with 2 layers of nail varnish except apical 3 ㎜. The roots were then immersed in 1% methylene blue dye for 7 days. Apical microleakage was measured by a maximum length of linear dye penetration after roots were separated longitudinally. One way ANOVA and Scheffe' s post-hoc test were performed for statistical analysis. Group 1 showed the least apical leakage and there was no statistical significance between Group 2, 3, 4. According to the results, the self adhesive resin cement is possible to use as sealer instead of primer & sealant when root canal filled by Resilon. 본 연구의 목적은 Resilon을 이용한 근관충전시 methacrylate-based root canal sealer와 자가-접착 레진시멘트의 사용에 따른 치근단 미세누출을 비교해 보는 것이다. 70개 단근치를 ProFile NiTi rotary instrument와 GG drill을 이용해 근관성형 하였다. 치근을 4개의 실험군 (n = 15)과 2개의 대조군 (n = 5)으로 분류하여 측방가압법으로 충전하였다. <1군: GP + AH-26, 2군: Resilon + RealSeal primer&sealant, 3군: Resilon + Rely-X Unicem 4군: Resilon + Biscem> 7일간 1% 메틸렌블루 용액에 침적 후 수직절단하여 치근첨부터 색소의 침투도를 측정하였다. 1군에서 가장 적은 미세누출값이 측정되었고, 2, 3, 4군 간의 통계적 유의성은 없었다. 이번 연구의 결과에 따르면, 자가-접착 레진시멘트는 Resilon을 이용한 근관충전시 sealer로 사용이 가능하리라 생각된다.

홍삼류의 섭취가 비만과 혈중 지질의 상호관계에 미치는 영향

박화진,이정희,이소진,함혜선,조현정,임창률,유영빈,박기현 대한의생명과학회 2000 Journal of biomedical laboratory sciences Vol.6 No.4

비만은 동맥경화의 위험인자로서 혈중에 triglyceride의 농도를 종가시키고, 상대적으로 HDL-Cholesterol의 농도를 감소시킴과 동시에 수축기 혈압을 상승시킨다. 본 연구에서 홍삼제품류를 4년 또는 5년 동안 복용해 온 건강한 사람 (ginseng군)과 홍삼제품을 복용하지 않은 건강한 사람 (control군)을 대상으로 하여 신체 계측치로부터 비만지수를 구하고 이것과 혈중의 triglyceride (TG)농도, TG/HDL-Cholesterol ratio 및 수축기 혈압과의 상호관계를 연구한 바, ginseng군에서는 대조군에 비해 혈중의 TG 농도가 일정하게 유지되었고, TG/HDL-Cholesterol ratio 및 수축기 혈압도 일정하게 유지되었다. 이러한 현상은 ginseng군에서 기호품으로 alcohol을 섭취하거나, 흡연을 한 경우에도 상관없이 일정하게 유지 되었다. 이 결과는 홍삼제품류를 장기 복용하면 비만의 저하 및 고혈압 또는 동맥경화의 위험인자가 억제될 수 있고, 결론적으로 비만, 고혈압 및 동맥경화를 예방할 수 있을 것으로 추정한다. Obesity is the risk fcactor of atherosclerosis and not only increases triglyceride concentration in blood but also decreases relatively the ratio of TG to HDL-Cholesterol in blood. In case of obesity, systolic blood pressure is also increased in responding the increase of TG in blood. Index of obesity in red ginseng-taking group (ginseng group) was lower as compared with non-red ginseng-taking group (control group). The TG concentration, the ratio of triglyceride to HDL-cholesterol in blood and systolic blood pressure were decreased in the subjects of ginseng group compared with that in control group. It is inferred that long-term intake of ginseng products may help to prevent the risk of atherosclerosis and obesity.

건강질단 질병 유소견자들의 순천향구미병원 외래이용에 영향을 미치는 요인

김진석,우극현,함정오,유재영,최태성,하봉구,윤성용 순천향의학연구소 2002 Journal of Soonchunhyang Medical Science Vol.8 No.1

Background ; The purpose of routine health screening of employee is not only to detect worker's disease at early stage but also to provide early appropriate health service. But, majority of patients who diagnosed by routine health screening haven't underwent health service utilization. Soonchunhyang Kumi Hospital had been provide total occupational health service in kumi industrial estate including health screening, worker interview at workplace by occupational nurses and doctors. Object ; We want to know how much proportion of patient who are diagnosed by routine health screening had visited Soonchunhyang Kumi hospital out-patient clinic and factors influencing such health care service utilization. Method ; Initial study subject were 189 workers who had proved to have hypertension, diabetes mellitus, hyperlipidemia in routine health screening which performed during year of 2000. Among those, 160 workers who had finished questionnaire were selected for final study subject. We investigate whether they had visited health services or not, if they had, what kind of health care facility they visited, and other factors which influencing their health service utilization. Result ; Among 160 workers, 59(36.9%) had visited Soonchunhyang Kumi hospital, 47(29.4%) had visited other health care facility, and 54(33.8%) had not went to any health care facility. Factors which influencing Soonchunhyang Kumi hospital utilization is sex, job, staff's support to hospital visit during worktime, history of medical consultation about health screening result.

졸참나무 수피의 추출성분

김진규,이상극,함연호,배영수 江原大學校 森林科學硏究所 2002 Journal of Forest Science Vol.18 No.-

졸참나무 수피를 채취하여 아세톤:물(7:3, v/v) 혼합용액으로 추출하고 유기용매를 제거한 후 hexane, CH₂Cl₂, EtOAc 및 수용성으로 분획하여 등결건조하였다. 그 중에서 EtOAc용성 분획물을 MeOH 수용액 및 EtOH-hexane 혼합용액을 사용하여 Sephadex LH-20 칼럼크로마토그래피를 수행하여 (+)-catechin, ellagic acid, taxifolin, taxifolin-3-O-β-D-glucopyranoside를 단리하였다. 단리된 화합물의 구조는 ¹H, ^(13)C-NMR spectrum으로 구조를 구명하였다. The bark of Quercus serrata Thunb were collected, extracted with acetone-H~O(7: 3, v/v), fractionated with hexane, methylene chloride and ethylacetate, and freeze dried to give some dark brown powder. The ethylacetate soluble mixture was chromatographed on a Sephadex LH-20 column using a series of aqueous methanol and ethanol-hexane mixture as eluents. The isolated compounds from &. serrata were (1- 1-catechin, ellagic acid taxifolin and taxifoiin-3-O-ll-D-glucop~anos~de. The structures of isolated compounds were characterized by ¹H, ^(13) C-NMR spectroscopy.