에어컨 냉각 팬용 브러쉬레스 DC 전동기의 역기전력 분석에 대한 연구

조정현,김지현,정정원,황흥식,이치우 경성대학교 공학기술연구소 2012 공학기술연구지 Vol.18 No.-

Compared to conventional dc motors having the combination of commutators and brushes, a brushless DC (BLDC) motor is one of the highly efficient motors due to its electrical commutation without a brush, and this feature allows the BLDC otor to be more suitable for an application requiring no maintenance due to mechanical wear between a commutator and a brush. Also, the BLDC motor has a few benefits over both a dc motor and an induction motor such as high dynamic response, high efficiency, logn life span, and low noise in wide speed-torque region. This paper investigates the variation of voltage induced in phase windings in a BLDC motor in several cases with respect to stack length, steel grade, and coil material. This study is numerically conducted and it is verified from the theoritical point of view by comparing the result of simulation with that of experimental measurement.

우울증 환자에서 성기능 장애

지익성,김영란,김정란 충남대학교 의학연구소 2001 충남의대잡지 Vol.28 No.2

There are several possible causes of sexual dysfunction in depressed disorder. However, patients will rarely report sexual problem spontaneously. Therefore, it is very difficult to determine a cause of sexual dysfunction in depressive patients, and the differential diagnosis must include primary sexual dysfunction, sexual dysfunction associated with general medical and psychiatric disorder, and sexual dysfunction associated with treatment for psychiatric disorder. Various strategies are recommended to manage antidepressant-induced sexual dysfunction in depression, including waiting, reducing the antidepressant dosage, use of drung holidays, use of adjunctive pharmacotherapy, and switching antidepressant. Use of an antidepressant with a low prevalence of sexual side effects, such as bupropion, nefazodone, and mirtazapine, may be the best way to avoid sexual dysfunction.

한국판 신체변형장애 척도개발을 위한 예비연구

김정란,지익성,신석철 大韓神經精神醫學會 1999 신경정신의학 Vol.38 No.4

연구목적 : 본 연구의 목적은 신체변형장애의 진단 및 심한 정도를 평가하는 자기 보고형 검사인 한국판 신체변형 장애 척도(BDDE-SR)를 개발하고 한국 청소년내의 신체 불만족에 대한 자료를 얻고자 하는데 있었다. 방 법 : 한국판 BDDE-SR을 대전 시내 남녀 고등학생 417명을 대상으로 설문을 하였고. 이 중 100명을 선정하여 6주 간격후 재검사를 하였다. 결 과 : 1) 전체 점수에 대한 검사-재검사 신뢰도(Pearson 상관계수)는 0.883(p〈0.001)으로 만족할 만한 신뢰도를 보였으며, 각 문항에 대한 검사-재검사 신뢰도는 통계적으로 유의하였다(Spearman 상광계수 범위:0.159∼0.761). 2) 내적 일치도는 Cronbach's α0.922(p〈0.01)로 높은 신뢰도를 보였다. 3) Varimax 회전에 의한 요인 분석의 결과, 5개의 요인을 추출하였는데, 제1요인은 고통과 당황인자, 제2요인은 자기 의식 및 부정적 평가 인자, 제3요인은 회피인자, 제4요인은 가리기 인자, 그리고 제5요인은 비교 인자였다. 4) 한국 청소년의 신체 불판족에 대한 자료에서, 전체 점수는 여학생 집단에서 52.4±24.8로 남학생집단의 37.7±20.6보다 유의하게 높았다. 남녀 고등학생을 합하여 가장 만족하지 못하는 신체부위는 허리-배(6.8%), 코(6.4%), 다리전체(6.0%), 치아와 눈(각각 5.9%) 순이었다. 결 론 : 이 결과들은 한국판 BDDE-SR이 신체변형장애의 평가를 위한 신뢰할 만한 도구임을 입증하는 것이며, 향후의 연구들에서 신체변형장애 환자군을 대상으로한 임상 자료를 얻고 한국판 BDDE-SR의 타당도 검증이 시행되어야 할 것으로 생각된다. Objective : The purposes of this study were to develop a Korean version of the Body Dysmorphic Disorder Examination-Self Report(BDDE-SR) and to get informations about the body dissatisfaction of the Korean adolescents. Method : A Korean version of the BDDE-SR was applied to 417 Korean high school adolescents. Retest was conducted with 6-week interval in 100 adolescents. Results : 1) Test-retest reliability of the total scores(Pearson's correlation coeffciency) was 0.883(p〈0.001) and test-retest reliabilities of each item also showed high correlation (Spearman's correlation coefficency range : 0.159-0.761). 2) Internal consistency by Cronbach's alpha of 0.922(p〈0.001) was very much high. 3) Five factors were extracted by factor analysis with the Varimax rotation. They were 'the distressing and embarrassment factor','the self-consciousness and negative self-evaluation factor','the avoidance factor','the camouflage factor', and'the comparison factor'. 4) The total score of BDDE-SR of girls was statistically higher(52.4±24.8) than that of boys(37.7±20.6). The most dissatisfied body part was abdomen (6.8%), nose (6.4%), entire leg (6.0%), teeth (5.9%) and eyes (5.9%) in all the subjects. Conclusion : These results indicate that a Korean version of the BDDE-SR is a reliable instrument for the assessment of Body Dysmorphic Disorder (BDD). The authors suggest that future researches should be directed to obtaining clinical of the patients with BDD and should test the validity of a Korean version of the BDDE-SR.

전신마취 후 발생한 악성고열증 환자의 치료 경험

이근무,정승환,이정한,정순호,최영균,김영재,신치만,박주열,이영민 白中央醫療院 2005 仁濟醫學 Vol.26 No.1

Malignant hyperthermia is the disorder of calcium regulation within skeletal muscle associated predominantly with anesthesia. It is triggered by volatile anesthetics and depolarizing neuromuscular blocking agents. We experienced a case of malignant hyperthermia. 50 years old female patient was transferred to our emergency room that she was developed tachyarrhythmia and high fever. She was taken arthroscopic examination under the general anesthesia with enflurane and succinylcholine. We suspected malignant hyperthermia and promptly treated her with dantrolene sodium. She was developed disseminated intravascular coagulopathy and acute renal failure then we were intensive care to her. She was discharged without sequela. We experienced successful management of malignant hyperthermia.

노년기에 처음으로 발생한 조증 삽화

신석철,김정란,지익성 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.1

It has been known that mania in the elderly was a uncommon condition, but the incidence of first admissions for mania tends to increase with advancing age. The etiology of late-onset mania appears to be more heterogeneous, which including identifiable causes, especially brain diseases. The psychopathology of late-onset mania is often attenuated and less severe than in the young. Lithium remains the primary medication in mania in the elderly. However, certain anticonvulsants (valproic acid and carbamazepine) have a number of advantages, including a more tolerable as patients with secondary mania due to neurological and other medical disorders. We report a case of first-episode mania in 73-year old woman, who was treated with valproic acid for 2 weeks to attain stabilizing her symptoms.

편도절제술을 받는 소아에서 수술 후 오심 및 구토에 대한 Propofol과 Ondansetron의 예방적 효과

김영재,구봉근,이정한,이근무,정순호,최영균,신치만 白中央醫療院 2005 仁濟醫學 Vol.26 No.1

Objective: To examine the prophylactic effect of ondansetron and propofol against postoperative nausea and vomiting(PONV) in children undergoing tonsill ectomy Methods and Materials: Sixty children(aged 3-11 years) who underwent tonsillectomy received antiemetics (ondansetron group; ondansetron 0.1mg/kg, propofol group; propofol 0.5mg/kg) or not (control group) at the end of surgery. Anesthesia was induced with ketamine(1mg/kgiv) and rocuronium(0.5mg/kg) and maintained by inhalation anesthesia with 2-3vol% sevoflurane in 50% N_(2)O/O_(2). Premedication was given as atropine 0.01mg/kg iv. Ketorolac(1mg/kg) was injected for postoperative analgesia immediate after induction. They were monitored the incidence of PONV at operation room, postanesthetic care unit(PACU) and admission room. Results: No significant differences were observed in the total incidence of PONV among the groups. But ondansetron and propofol group made a difference(p<0.05) in the incidence of PONV at operation room compared with control group. Conclusion: In children undergoing tonsillectomy, ondansetron(0.1mg/kg) and propofol(0.5mg/kg) may have a prophylactic effect against PONV at operation room.

복식자궁전적출술과 인공슬관절 치환술 환자에서 정맥내 자가통증조절이 수술 후 진통에 미치는 효과

최영균,남현옥,이정한,이근무,정순호,김영재,신치만 白中央醫療院 2005 仁濟醫學 Vol.26 No.1

Objective: Intravenous patient-controlled analgesia(IV PCA) is gaining wide spread popularity in the management of postoperative pain control. The purpose of this study is to evaluate the severity of pain after TAH and TKRA through comparing visual analogue scale(VAS) of pain of each patients who received identical IV PCA protocol, and to improve our IV PCA protocol. Methods: TAH group includes twenty female patients who were scheduled for TAH. TKRA group includes twenty female patients who were scheduled for TKRA. Each group received fentanyl 50㎍ about 30minutes before the end of surgery, followed by IV PCA with fentanyl 1500 ㎍, ketolorac 300mg, ondansteron 8mg, normal saline 56㎖(total 96ml, basal infusion rate 1㎖/hr, bolus dose 1㎖, lockout time 10 minutes). VAS scores were recorded at 1, 6, 12, 24, 48 hours postoperatively. Total bolus doses and patients' satisfaction were checked after the end of analgesia. Results: VAS scores of TKRA group were significantly higher than those of TAH group at 12, 24, 48 hours postoperatively. VAS scores of both group progressively decreased(P<0.05). Patients' satisfaction score showed no significant difference between two groups. Total bolus dose of TKRA group was significantly higher than that of TAH. Conclusion: The postoperative pain of TKRA was more severe than that of TAH. TKRA group needed more profound postoperative pain control than TAH group. We should consider the increase of early postoperative period analgesic doses to acquire optimal pain control of both group.

전기경련요법에서 remifentanil이 혈역학에 미치는 효과

정순호,이상은,임세훈,이정한,이근무,최영균,김영재,신치만 白中央醫療院 2005 仁濟醫學 Vol.26 No.1

Objective: Electroconvulsive therapy (ECT) is often associated with transient hypertension and tachycardia. Acute hemodynamic change may produce serious complications. Remifentanil is a potent ultra short acting opioid and has been found to reduce blood pressure and heart rate. The goal of this study was to evaluate effects of remifentanil on seizure duration, recovery parameters and hemodynamic changes during ECT. Methods: Ten ASA Ⅰ, Ⅱ patients enrolled in this prospective, randomized trial, each receiving more than four electroconvulsive therapy. Patients were randomized to receive placebo, group P (propofol 1mg/kg+0.9% normal saline 1ml, n=10), and propofol with remifentanil, group R (propofol 1mg/kg+remifentanil 1ug/Kg n=10). Supplemental dose of propofol was given as required to achieve loss of consciousness. We recorded hemodynamic parameters, seizure duration, and recovery parameters. Results: Seizure duration and recovery parameters were similar in group R and group P. Blood pressure and Hear rate after ECT were significantly lower in group R. Conclusions: Remifentanil(1ug/kg) attenuated the acute hemodynamic response to ECT under propofol anesthesia without adversely affecting the duration of seizure activity and recovery profile. Adjunctive use of remifentanil may be good alternative regimens for ECT.

Quartz 자극에 의한 iNOS 발현의 자가조절

김경아,남혜윤,문제혁,정진숙,임영,정치경 大韓産業醫學會 2001 대한직업환경의학회지 Vol.13 No.4

목적 : Rat2 섬유모세포에서 α-quartz에 의해 유도된 NOS의 조절기전을 알아보기 위하여 본 연구가시도 되었다. 방법 : Rat2 세포에 있어서 α-quartz 자극에 의한 NO와 H₂O₂의 분비 및 iNOS의 발현을 관찰하였고, iNOS 억제제인 L-NIL과 H₂O₂ 억제제인Catalase를 전처리하고 마찬가지로 NO와 H₂O₂분비 그리고 iNOS의 단백발현 정도를 western blot-ting을 이용하여 관찰하였다. 결과 : o-quartz는 Rat2 세포에서 iNOS에 의한NO와 H₂O₂의 분비를 유도하였다. L-NIL은 R3t2세포에서 D-quartz에 의한 H₂O₂의 분비와 iNOS발현을 완전히 억제하였다. Catalase로 전처리 하였을 때 o-quartz로 유도된 iNOS에 의하여 생산증가된 H2Oa가 iNOS를 억제하는 autoinhibitorypathway가 차단되어 결과적으로 H₂O₂의 분비와 iNOS의 발현이 증가하였다. 결론 : Rat2 세포에서 α-quartz에 의하여 유도된iNOS는 H₂O₂의 분비를 촉진하고 이 H₂O₂는 iNOS기능을 조절하는 자가조절기전에 중요한 역할을 하는 것으로 생각된다. Objectives : This study was performed in order to investigate the molecular mechanism regulating nitric oxide synthase (NOS) induced by α-quartz in Rat2 fibroblast. Methods : α-quartz-induced nitric Oxide (NO) anti H₂O₂ formation anti α-quarts-induced iNOS protein expression in Rat2 fibroblast were monitored. With iNOS inhibitor (L-N6- (1-iminoethyl) lysine hydrochloride, L-NIL) or antioxidant (catalase), we observed NO and H₂O₂ formation and iNOS protein expression in Rat2 fibroblast stimulated with α-quartz. Results : α-quartz stimulated iNOS-induced NO and H₂O₂ formation in Rat2 fibroblast. L-NIL inhibited H₂O₂ formation and iNOS protein expression by α-quartz in Rat2 fibroblast. Pretreatment with catalase blocked the autoinhibitory pathway of iNOS by iNOS-induced H₂O₂ therefore H₂O₂ and NO production and iNOS protein expression were increased in Rat2 fibrobalst stimulated with α-quartz Conclusion : α-quartz-induced iNOS Stimulated H₂O₂ formation in Rat2 fibroblast. INOS-induced H₂O₂ by α-quartz plays an important role in the autoinhibition pathway for regulating the iNOS function in Rat2 fibroblast

동일한 혈관 내에 발생한 이식형 약제 주입기 카테터의 위치이상

오대석,김영재,김명훈,조광래,임세훈,이정한,이근무,정순호,신치만 仁濟大學校 白病院 2010 仁濟醫學 Vol.31 No.-

저자들은 56세 여성 환자의 왼쪽 쇄골 하 정맥에 시행한 이식형 약제주입기 카테터의 삽입 후 발생한 비정상 위치에 대한 증례를 보고하고자 한다. 카테터의 끝은 환자의 늘 어진 가슴, 체위, 신체의 움직임, 카테터의 유동성 등의 영향으로 천자된 정맥 내에서 견인되고 뒤쪽으로 이동하였다. 환자는 어떠한 증상도 호소하지 않았지만 비정상 위치의 카테터는 심각한 합병증을 유발할 수 있기 때문에 제거되었다. 따라서 시술자는 약제주입기 삽입 전에 환자의 신체 상태와 단순 흉부 촬영상을 확인하고 카테터의 비정상 위치가 발생할 수 있는 위험 징후를 알아차려야 하겠다.